Mus musculus

173 known processes

Ctsh

cathepsin H

(Aliases: AL022844)

Ctsh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leukocyte mediated immunity GO:0002443 174 0.517
lymphocyte mediated immunity GO:0002449 139 0.450
adaptive immune response GO:0002250 155 0.242
immune effector process GO:0002252 321 0.190
negative regulation of immune system process GO:0002683 209 0.157
oxidation reduction process GO:0055114 342 0.142
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.138
angiogenesis GO:0001525 201 0.130
leukocyte mediated cytotoxicity GO:0001909 62 0.122
innate immune response GO:0045087 157 0.117
cytokine production GO:0001816 319 0.114
response to lipopolysaccharide GO:0032496 128 0.111
respiratory tube development GO:0030323 167 0.108
t cell mediated immunity GO:0002456 50 0.107
regulation of defense response GO:0031347 233 0.104
mapk cascade GO:0000165 281 0.097
Human
cellular protein catabolic process GO:0044257 155 0.092
protein activation cascade GO:0072376 19 0.088
cellular ketone metabolic process GO:0042180 84 0.087
macromolecule catabolic process GO:0009057 281 0.085
positive regulation of transferase activity GO:0051347 167 0.083
regulation of protein kinase activity GO:0045859 232 0.082
reactive oxygen species metabolic process GO:0072593 84 0.082
regulation of cytokine production GO:0001817 266 0.081
t cell activation GO:0042110 289 0.080
fatty acid metabolic process GO:0006631 121 0.078
positive regulation of protein modification process GO:0031401 299 0.077
regulation of transferase activity GO:0051338 263 0.075
cellular macromolecule catabolic process GO:0044265 206 0.075
regulation of leukocyte mediated immunity GO:0002703 104 0.069
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.069
antigen processing and presentation of exogenous antigen GO:0019884 26 0.068
defense response to bacterium GO:0042742 119 0.068
positive regulation of innate immune response GO:0045089 80 0.068
activation of immune response GO:0002253 138 0.067
regulation of mapk cascade GO:0043408 248 0.067
positive regulation of defense response GO:0031349 124 0.065
leukocyte differentiation GO:0002521 342 0.065
cellular lipid metabolic process GO:0044255 323 0.065
amine metabolic process GO:0009308 45 0.065
positive regulation of protein phosphorylation GO:0001934 242 0.062
t cell mediated cytotoxicity GO:0001913 26 0.062
cellular amino acid metabolic process GO:0006520 103 0.061
defense response to other organism GO:0098542 197 0.061
positive regulation of mapk cascade GO:0043410 170 0.060
regulation of secretion by cell GO:1903530 249 0.060
positive regulation of programmed cell death GO:0043068 218 0.060
negative regulation of cell proliferation GO:0008285 296 0.059
lipid biosynthetic process GO:0008610 179 0.059
response to molecule of bacterial origin GO:0002237 143 0.058
inflammatory response GO:0006954 244 0.055
cellular response to extracellular stimulus GO:0031668 81 0.055
cellular amine metabolic process GO:0044106 44 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.054
myeloid cell differentiation GO:0030099 233 0.053
wound healing GO:0042060 157 0.053
cellular response to molecule of bacterial origin GO:0071219 83 0.052
vesicle organization GO:0016050 60 0.051
monocarboxylic acid metabolic process GO:0032787 191 0.050
epithelial cell proliferation GO:0050673 174 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.050
cellular response to lipid GO:0071396 145 0.049
lipid catabolic process GO:0016042 69 0.048
antigen processing and presentation GO:0019882 47 0.048
blood vessel morphogenesis GO:0048514 285 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
cation transport GO:0006812 399 0.047
regulation of epithelial cell proliferation GO:0050678 141 0.047
response to oxidative stress GO:0006979 123 0.047
maintenance of location GO:0051235 89 0.046
regulation of secretion GO:0051046 274 0.046
t cell differentiation GO:0030217 174 0.045
hormone metabolic process GO:0042445 86 0.044
regulation of inflammatory response GO:0050727 147 0.044
cellular response to lipopolysaccharide GO:0071222 77 0.044
cellular response to nutrient levels GO:0031669 64 0.044
lipid transport GO:0006869 98 0.044
membrane organization GO:0061024 245 0.044
regulation of membrane potential GO:0042391 192 0.044
activation of mapk activity GO:0000187 59 0.043
vacuole organization GO:0007033 38 0.043
regulation of cellular catabolic process GO:0031329 242 0.042
regulation of system process GO:0044057 200 0.042
regulation of kinase activity GO:0043549 249 0.041
regulation of response to wounding GO:1903034 189 0.041
cell activation involved in immune response GO:0002263 126 0.041
heterocycle catabolic process GO:0046700 280 0.041
male gamete generation GO:0048232 285 0.040
Rat
regulation of protein serine threonine kinase activity GO:0071900 157 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
lung development GO:0030324 164 0.039
myeloid cell activation involved in immune response GO:0002275 34 0.038
regulation of cell activation GO:0050865 289 0.038
alpha beta t cell activation GO:0046631 91 0.038
organic anion transport GO:0015711 137 0.038
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.037
glucose homeostasis GO:0042593 128 0.037
small molecule biosynthetic process GO:0044283 132 0.037
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.037
humoral immune response GO:0006959 57 0.037
regulation of adaptive immune response GO:0002819 90 0.037
olfactory learning GO:0008355 2 0.037
lymphocyte proliferation GO:0046651 164 0.037
erk1 and erk2 cascade GO:0070371 77 0.036
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
negative regulation of cell activation GO:0050866 111 0.035
protein secretion GO:0009306 111 0.035
positive regulation of apoptotic process GO:0043065 217 0.035
reactive oxygen species biosynthetic process GO:1903409 8 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
jnk cascade GO:0007254 72 0.035
carbohydrate metabolic process GO:0005975 230 0.034
striated muscle tissue development GO:0014706 293 0.034
positive regulation of protein kinase activity GO:0045860 144 0.034
peptidyl amino acid modification GO:0018193 336 0.033
negative regulation of intracellular signal transduction GO:1902532 167 0.033
regulation of leukocyte differentiation GO:1902105 159 0.033
endocytosis GO:0006897 168 0.033
cellular response to biotic stimulus GO:0071216 92 0.032
protein catabolic process GO:0030163 221 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
b cell activation GO:0042113 161 0.032
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.032
response to steroid hormone GO:0048545 56 0.032
peptidyl tyrosine phosphorylation GO:0018108 143 0.031
regulation of cell migration GO:0030334 219 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
regulation of erk1 and erk2 cascade GO:0070372 71 0.031
regulation of lymphocyte proliferation GO:0050670 117 0.031
apoptotic signaling pathway GO:0097190 306 0.031
cellular protein complex assembly GO:0043623 116 0.031
stress activated protein kinase signaling cascade GO:0031098 81 0.030
positive regulation of cellular catabolic process GO:0031331 148 0.030
positive regulation of cytokine production GO:0001819 174 0.030
aromatic compound catabolic process GO:0019439 286 0.029
regulation of map kinase activity GO:0043405 120 0.029
regulation of hormone levels GO:0010817 211 0.029
regulation of intracellular transport GO:0032386 159 0.029
positive regulation of secretion GO:0051047 130 0.028
regulation of lymphocyte mediated immunity GO:0002706 84 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.028
carboxylic acid catabolic process GO:0046395 51 0.028
nitrogen compound transport GO:0071705 271 0.028
ear development GO:0043583 200 0.028
regulation of proteolysis GO:0030162 164 0.028
lipid localization GO:0010876 126 0.028
positive regulation of map kinase activity GO:0043406 84 0.027
antigen processing and presentation of peptide antigen GO:0048002 29 0.027
positive regulation of secretion by cell GO:1903532 114 0.027
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.027
neuronal action potential GO:0019228 54 0.027
respiratory system development GO:0060541 190 0.027
monosaccharide metabolic process GO:0005996 106 0.026
carbohydrate homeostasis GO:0033500 128 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
positive regulation of protein catabolic process GO:0045732 60 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
myelination GO:0042552 74 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
cellular homeostasis GO:0019725 240 0.026
reactive nitrogen species metabolic process GO:2001057 0 0.026
entry into host cell GO:0030260 15 0.026
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.026
regulation of peptidase activity GO:0052547 96 0.026
positive regulation of kinase activity GO:0033674 155 0.025
negative regulation of leukocyte differentiation GO:1902106 51 0.025
nucleotide metabolic process GO:0009117 332 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
learning or memory GO:0007611 148 0.025
leukocyte activation involved in immune response GO:0002366 126 0.025
negative regulation of phosphorylation GO:0042326 166 0.025
glycerolipid metabolic process GO:0046486 122 0.025
regulation of hydrolase activity GO:0051336 246 0.025
regulation of cellular protein catabolic process GO:1903362 61 0.025
hexose metabolic process GO:0019318 98 0.024
purine containing compound metabolic process GO:0072521 311 0.024
metal ion homeostasis GO:0055065 189 0.024
developmental maturation GO:0021700 193 0.024
immune response regulating signaling pathway GO:0002764 125 0.024
Human
positive regulation of nervous system development GO:0051962 221 0.024
cytoplasmic transport GO:0016482 234 0.024
anatomical structure homeostasis GO:0060249 145 0.024
Human
response to organic cyclic compound GO:0014070 198 0.024
spermatogenesis GO:0007283 284 0.024
Rat
negative regulation of inflammatory response GO:0050728 61 0.024
sphingolipid catabolic process GO:0030149 7 0.024
intracellular protein transport GO:0006886 204 0.023
positive regulation of jun kinase activity GO:0043507 30 0.023
positive regulation of protein transport GO:0051222 93 0.023
negative regulation of protein modification process GO:0031400 163 0.023
regulation of cellular response to stress GO:0080135 159 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
interferon gamma production GO:0032609 67 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
organic hydroxy compound transport GO:0015850 93 0.023
lateral inhibition GO:0046331 1 0.023
regulation of homeostatic process GO:0032844 182 0.023
cell killing GO:0001906 67 0.023
carboxylic acid biosynthetic process GO:0046394 86 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
acute inflammatory response GO:0002526 41 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
Human
regulation of protein catabolic process GO:0042176 108 0.022
positive regulation of immune effector process GO:0002699 107 0.022
regulation of cell cycle GO:0051726 281 0.022
lipid modification GO:0030258 65 0.022
leukocyte proliferation GO:0070661 172 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
immunoglobulin mediated immune response GO:0016064 69 0.022
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.021
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.021
autophagy GO:0006914 45 0.021
cation homeostasis GO:0055080 212 0.021
cell adhesion GO:0007155 329 0.021
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.021
sensory perception GO:0007600 245 0.021
multicellular organismal signaling GO:0035637 91 0.021
homeostasis of number of cells GO:0048872 210 0.021
positive regulation of jnk cascade GO:0046330 46 0.021
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.020
circulatory system process GO:0003013 197 0.020
small molecule catabolic process GO:0044282 71 0.020
transmembrane transport GO:0055085 412 0.020
cellular ion homeostasis GO:0006873 165 0.020
blood coagulation GO:0007596 76 0.019
muscle tissue development GO:0060537 308 0.019
transition metal ion transport GO:0000041 38 0.019
regulation of leukocyte proliferation GO:0070663 121 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
tissue homeostasis GO:0001894 115 0.019
Human
regulation of body fluid levels GO:0050878 162 0.019
branching morphogenesis of an epithelial tube GO:0048754 159 0.019
regulation of protein transport GO:0051223 163 0.019
lymphocyte activation involved in immune response GO:0002285 93 0.019
action potential GO:0001508 78 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
cell cell adhesion GO:0098609 41 0.019
response to nutrient levels GO:0031667 109 0.019
myeloid leukocyte activation GO:0002274 83 0.019
positive regulation of response to wounding GO:1903036 66 0.019
skin development GO:0043588 220 0.019
regulation of protein localization GO:0032880 231 0.019
cytokine secretion GO:0050663 72 0.019
negative regulation of molecular function GO:0044092 258 0.019
organic acid catabolic process GO:0016054 51 0.019
cell type specific apoptotic process GO:0097285 268 0.019
glycosyl compound catabolic process GO:1901658 206 0.018
skeletal system development GO:0001501 356 0.018
steroid metabolic process GO:0008202 119 0.018
immune response activating signal transduction GO:0002757 116 0.018
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.018
positive regulation of inflammatory response GO:0050729 47 0.018
gland development GO:0048732 330 0.018
epidermis development GO:0008544 187 0.018
regulation of neuron projection development GO:0010975 169 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
transmission of nerve impulse GO:0019226 76 0.018
tissue remodeling GO:0048771 102 0.018
cognition GO:0050890 149 0.018
regulation of cell motility GO:2000145 236 0.018
norepinephrine secretion GO:0048243 2 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.018
calcium ion transport GO:0006816 159 0.018
cellular response to organonitrogen compound GO:0071417 145 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
interleukin 6 production GO:0032635 58 0.017
myeloid cell homeostasis GO:0002262 114 0.017
stem cell differentiation GO:0048863 268 0.017
positive regulation of stress activated mapk cascade GO:0032874 48 0.017
ceramide metabolic process GO:0006672 31 0.017
positive regulation of epithelial cell proliferation GO:0050679 68 0.017
negative regulation of transferase activity GO:0051348 85 0.017
single fertilization GO:0007338 82 0.017
leukocyte apoptotic process GO:0071887 71 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
response to growth factor GO:0070848 198 0.017
positive regulation of cellular protein catabolic process GO:1903364 34 0.017
regulation of blood pressure GO:0008217 93 0.017
negative regulation of mapk cascade GO:0043409 65 0.017
bone remodeling GO:0046849 53 0.017
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.017
regulation of protein secretion GO:0050708 82 0.017
t cell proliferation GO:0042098 120 0.017
positive regulation of adaptive immune response GO:0002821 61 0.017
cellular response to starvation GO:0009267 57 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
cellular response to external stimulus GO:0071496 88 0.016
blood circulation GO:0008015 195 0.016
cellular response to hydroperoxide GO:0071447 4 0.016
divalent metal ion transport GO:0070838 172 0.016
sphingolipid metabolic process GO:0006665 45 0.016
response to extracellular stimulus GO:0009991 127 0.016
nucleoside metabolic process GO:0009116 246 0.016
glycosphingolipid catabolic process GO:0046479 5 0.016
anion transport GO:0006820 177 0.016
cellular response to epidermal growth factor stimulus GO:0071364 4 0.016
muscle cell differentiation GO:0042692 261 0.016
positive regulation of proteolysis GO:0045862 85 0.016
negative regulation of protein activation cascade GO:2000258 3 0.015
regulation of innate immune response GO:0045088 91 0.015
response to acid chemical GO:0001101 111 0.015
multi multicellular organism process GO:0044706 109 0.015
response to organonitrogen compound GO:0010243 246 0.015
cytokine production involved in immune response GO:0002367 34 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
negative regulation of hypersensitivity GO:0002884 3 0.015
regulation of retina development in camera type eye GO:1902866 3 0.015
interleukin 8 production GO:0032637 4 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
regulation of neuron differentiation GO:0045664 281 0.015
negative regulation of map kinase activity GO:0043407 34 0.015
complement activation GO:0006956 16 0.015
ion transmembrane transport GO:0034220 361 0.015
positive regulation of cell activation GO:0050867 158 0.015
triglyceride metabolic process GO:0006641 51 0.015
cellular chemical homeostasis GO:0055082 215 0.015
eosinophil migration GO:0072677 3 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
chemotaxis GO:0006935 247 0.015
muscle cell development GO:0055001 133 0.015
regulation of organelle organization GO:0033043 289 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
male gonad development GO:0008584 88 0.014
muscle system process GO:0003012 141 0.014
regulation of mast cell activation GO:0033003 21 0.014
development of primary male sexual characteristics GO:0046546 88 0.014
regulation of leukocyte apoptotic process GO:2000106 56 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
negative regulation of lymphocyte activation GO:0051250 91 0.014
gliogenesis GO:0042063 141 0.014
lymphocyte differentiation GO:0030098 242 0.014
exocytosis GO:0006887 121 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
male sex differentiation GO:0046661 109 0.014
organic acid biosynthetic process GO:0016053 86 0.014
interleukin 8 secretion GO:0072606 3 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
regulation of interleukin 6 production GO:0032675 55 0.014
fat cell differentiation GO:0045444 160 0.014
neuron death GO:0070997 154 0.014
regulation of muscle tissue development GO:1901861 97 0.014
myeloid leukocyte mediated immunity GO:0002444 42 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
hindbrain development GO:0030902 128 0.014
keratinocyte proliferation GO:0043616 21 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
organ regeneration GO:0031100 2 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
sequestering of metal ion GO:0051238 19 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
renal protein absorption GO:0097017 1 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
regulation of b cell activation GO:0050864 81 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
stress activated mapk cascade GO:0051403 80 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
hemostasis GO:0007599 78 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
oligosaccharide catabolic process GO:0009313 2 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
actin cytoskeleton organization GO:0030036 220 0.013
regulation of keratinocyte proliferation GO:0010837 15 0.013
sensory perception of sound GO:0007605 97 0.013
regulation of cell projection organization GO:0031344 206 0.013
learning GO:0007612 98 0.013
axonogenesis GO:0007409 274 0.013
organelle assembly GO:0070925 177 0.013
lytic vacuole organization GO:0080171 21 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
endomembrane system organization GO:0010256 147 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
Human Rat
regulation of interleukin 8 secretion GO:2000482 2 0.013
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.013
placenta development GO:0001890 140 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
regulation of t cell mediated immunity GO:0002709 34 0.013
carboxylic acid transport GO:0046942 100 0.013
t cell activation involved in immune response GO:0002286 43 0.013
astrocyte cell migration GO:0043615 3 0.013
negative regulation of cytokine production GO:0001818 84 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
regulation of t cell activation GO:0050863 170 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
glycolipid metabolic process GO:0006664 25 0.013
hormone secretion GO:0046879 128 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
negative regulation of defense response GO:0031348 77 0.012
phospholipid metabolic process GO:0006644 87 0.012
leukocyte homeostasis GO:0001776 79 0.012
cellularization GO:0007349 1 0.012
negative regulation of epithelial cell proliferation GO:0050680 64 0.012
protein ubiquitination GO:0016567 171 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
protein localization to organelle GO:0033365 185 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
skeletal muscle organ development GO:0060538 163 0.012
neuron apoptotic process GO:0051402 142 0.012
locomotory behavior GO:0007626 195 0.012
nucleoside catabolic process GO:0009164 206 0.012
regulation of anatomical structure size GO:0090066 178 0.012
regulation of protein stability GO:0031647 52 0.012
regulation of phospholipase a2 activity GO:0032429 3 0.012
positive regulation of cell death GO:0010942 224 0.012
myotube cell development GO:0014904 60 0.012
regulated secretory pathway GO:0045055 32 0.012
thymocyte migration GO:0072679 2 0.012
fertilization GO:0009566 127 0.012
positive regulation of endocytosis GO:0045807 42 0.012
negative regulation of complement activation GO:0045916 3 0.012
molting cycle GO:0042303 90 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
monosaccharide transport GO:0015749 58 0.012
nuclear transport GO:0051169 139 0.012
toll like receptor signaling pathway GO:0002224 38 0.012
cellular lipid catabolic process GO:0044242 52 0.012
telencephalon development GO:0021537 186 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
carbohydrate catabolic process GO:0016052 32 0.012
unsaturated fatty acid biosynthetic process GO:0006636 15 0.012
organelle localization GO:0051640 179 0.012
divalent inorganic cation transport GO:0072511 178 0.012
phagosome maturation GO:0090382 4 0.012
regulation of protein maturation GO:1903317 96 0.012
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
hexose transport GO:0008645 56 0.011
sterol transport GO:0015918 38 0.011
acute inflammatory response to antigenic stimulus GO:0002438 12 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
dna metabolic process GO:0006259 303 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
alcohol metabolic process GO:0006066 116 0.011
metanephric glomerular epithelial cell development GO:0072313 2 0.011
defecation GO:0030421 1 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
germ cell development GO:0007281 185 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.011
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.011
protein autoprocessing GO:0016540 2 0.011
negative regulation of proteolysis GO:0045861 74 0.011
negative regulation of t cell proliferation GO:0042130 38 0.011
positive regulation of apoptotic cell clearance GO:2000427 3 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
regulation of ossification GO:0030278 112 0.011
sulfur compound metabolic process GO:0006790 100 0.011
kidney development GO:0001822 213 0.011
Rat
amide transport GO:0042886 138 0.011
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
actin filament organization GO:0007015 113 0.011
regionalization GO:0003002 337 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
pattern recognition receptor signaling pathway GO:0002221 47 0.011
striated muscle cell development GO:0055002 125 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
keratinocyte differentiation GO:0030216 48 0.011
b cell mediated immunity GO:0019724 71 0.011
synapse organization GO:0050808 125 0.011

Ctsh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.781
inherited metabolic disorder DOID:655 0 0.781
disease of anatomical entity DOID:7 0 0.207
nervous system disease DOID:863 0 0.207
immune system disease DOID:2914 0 0.133
lysosomal storage disease DOID:3211 0 0.099
retinal disease DOID:5679 0 0.077
retinal degeneration DOID:8466 0 0.077
sensory system disease DOID:0050155 0 0.077
eye and adnexa disease DOID:1492 0 0.077
eye disease DOID:5614 0 0.077
central nervous system disease DOID:331 0 0.060
integumentary system disease DOID:16 0 0.035
brain disease DOID:936 0 0.032
lipid storage disease DOID:9455 0 0.032
sphingolipidosis DOID:1927 0 0.032
hemolytic anemia DOID:583 0 0.031
hemolytic uremic syndrome DOID:12554 0 0.031
normocytic anemia DOID:720 0 0.031
anemia DOID:2355 0 0.031
hematopoietic system disease DOID:74 0 0.031
metal metabolism disorder DOID:896 0 0.020
neurodegenerative disease DOID:1289 0 0.018
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
skin disease DOID:37 0 0.012