Mus musculus

0 known processes

Fkbp3

FK506 binding protein 3

(Aliases: FKBP-3,25kDa,FKBP25)

Fkbp3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male gamete generation GO:0048232 285 0.477
spermatogenesis GO:0007283 284 0.221
protein modification by small protein conjugation or removal GO:0070647 207 0.178
establishment of organelle localization GO:0051656 122 0.151
dna metabolic process GO:0006259 303 0.139
generation of precursor metabolites and energy GO:0006091 103 0.122
regulation of ion transport GO:0043269 215 0.119
positive regulation of cell death GO:0010942 224 0.105
positive regulation of apoptotic process GO:0043065 217 0.101
germ cell development GO:0007281 185 0.085
forebrain development GO:0030900 302 0.075
translation GO:0006412 93 0.075
synaptic transmission GO:0007268 329 0.074
macromolecule catabolic process GO:0009057 281 0.071
muscle adaptation GO:0043500 39 0.070
negative regulation of molecular function GO:0044092 258 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.065
positive regulation of cellular amine metabolic process GO:0033240 5 0.064
nucleoside metabolic process GO:0009116 246 0.064
regulation of transmembrane transport GO:0034762 128 0.064
regulation of endopeptidase activity GO:0052548 89 0.062
purine nucleotide metabolic process GO:0006163 302 0.060
blood circulation GO:0008015 195 0.059
learning or memory GO:0007611 148 0.058
transmembrane transport GO:0055085 412 0.058
cognition GO:0050890 149 0.056
protein neddylation GO:0045116 1 0.055
positive regulation of apoptotic signaling pathway GO:2001235 95 0.054
organelle localization GO:0051640 179 0.054
regulation of ion transmembrane transport GO:0034765 119 0.053
anatomical structure homeostasis GO:0060249 145 0.051
regulation of proteolysis GO:0030162 164 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.047
apoptotic signaling pathway GO:0097190 306 0.047
energy derivation by oxidation of organic compounds GO:0015980 77 0.047
regulation of cellular catabolic process GO:0031329 242 0.046
mitochondrion organization GO:0007005 134 0.046
spermatid development GO:0007286 108 0.045
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
regulation of muscle system process GO:0090257 80 0.044
protein catabolic process GO:0030163 221 0.043
positive regulation of programmed cell death GO:0043068 218 0.042
cation transport GO:0006812 399 0.042
muscle cell differentiation GO:0042692 261 0.041
regulation of transporter activity GO:0032409 57 0.040
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.039
glycosyl compound metabolic process GO:1901657 246 0.038
regulation of peptidase activity GO:0052547 96 0.038
ribonucleoside metabolic process GO:0009119 245 0.037
development of primary sexual characteristics GO:0045137 143 0.037
protein processing GO:0016485 163 0.036
dna replication GO:0006260 52 0.035
organelle fission GO:0048285 170 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.035
nucleotide metabolic process GO:0009117 332 0.034
cell division GO:0051301 120 0.034
regulation of heart contraction GO:0008016 77 0.033
trna processing GO:0008033 11 0.033
nucleobase containing compound transport GO:0015931 27 0.033
cellular ketone metabolic process GO:0042180 84 0.032
positive regulation of ion transport GO:0043270 65 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
microtubule based process GO:0007017 236 0.031
ion transmembrane transport GO:0034220 361 0.031
sperm individualization GO:0007291 1 0.030
protein maturation GO:0051604 176 0.030
purine containing compound metabolic process GO:0072521 311 0.030
regulation of binding GO:0051098 111 0.029
cellular amine metabolic process GO:0044106 44 0.029
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
rna interference GO:0016246 2 0.028
ras protein signal transduction GO:0007265 77 0.028
amine metabolic process GO:0009308 45 0.027
heart process GO:0003015 94 0.027
neurotransmitter transport GO:0006836 76 0.026
double strand break repair GO:0006302 48 0.026
response to organic cyclic compound GO:0014070 198 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
telencephalon development GO:0021537 186 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.025
calcium ion transmembrane transport GO:0070588 85 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
regulation of cell cycle GO:0051726 281 0.025
muscle tissue development GO:0060537 308 0.024
regulation of translation GO:0006417 71 0.024
regulation of hydrolase activity GO:0051336 246 0.023
muscle system process GO:0003012 141 0.023
rna splicing GO:0008380 54 0.023
spermatid differentiation GO:0048515 115 0.023
mitotic cell cycle GO:0000278 195 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
atp metabolic process GO:0046034 75 0.022
cell fate commitment GO:0045165 210 0.022
positive regulation of proteolysis GO:0045862 85 0.022
cellular amino acid metabolic process GO:0006520 103 0.022
histone h4 k20 trimethylation GO:0034773 2 0.022
microtubule cytoskeleton organization GO:0000226 157 0.021
cation transmembrane transport GO:0098655 266 0.021
gonad development GO:0008406 141 0.021
detection of abiotic stimulus GO:0009582 60 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
positive regulation of endopeptidase activity GO:0010950 43 0.020
regulation of blood circulation GO:1903522 93 0.020
actomyosin structure organization GO:0031032 56 0.020
positive regulation of organelle organization GO:0010638 128 0.020
purine nucleoside monophosphate metabolic process GO:0009126 81 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.020
peptidyl lysine modification GO:0018205 77 0.020
protein ubiquitination GO:0016567 171 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.019
regulation of nuclear division GO:0051783 56 0.019
dna repair GO:0006281 107 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of long term synaptic potentiation GO:1900271 4 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
regulation of protein catabolic process GO:0042176 108 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
regulation of cell division GO:0051302 76 0.018
regulation of organelle organization GO:0033043 289 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
cytokinetic process GO:0032506 2 0.018
ncrna processing GO:0034470 26 0.017
striated muscle tissue development GO:0014706 293 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.017
lipid localization GO:0010876 126 0.017
multicellular organism growth GO:0035264 161 0.017
adult behavior GO:0030534 135 0.017
regulation of muscle hypertrophy GO:0014743 13 0.017
cellularization GO:0007349 1 0.017
ribonucleoside catabolic process GO:0042454 206 0.016
zymogen activation GO:0031638 41 0.016
microtubule organizing center organization GO:0031023 28 0.016
peptidyl amino acid modification GO:0018193 336 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
regulation of muscle adaptation GO:0043502 31 0.015
respiratory system development GO:0060541 190 0.015
epithelial cell proliferation GO:0050673 174 0.015
cell type specific apoptotic process GO:0097285 268 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
cellular protein catabolic process GO:0044257 155 0.014
cardiac muscle hypertrophy GO:0003300 23 0.014
somatic diversification of immune receptors GO:0002200 53 0.014
translational initiation GO:0006413 24 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
carbohydrate metabolic process GO:0005975 230 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
synapse assembly GO:0007416 56 0.014
heterocycle catabolic process GO:0046700 280 0.014
muscle contraction GO:0006936 101 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
calcium ion transport GO:0006816 159 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
response to dsrna GO:0043331 30 0.013
divalent inorganic cation transport GO:0072511 178 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
ribonucleoprotein complex localization GO:0071166 1 0.013
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
response to organonitrogen compound GO:0010243 246 0.013
positive regulation of protein modification process GO:0031401 299 0.013
cellular glucan metabolic process GO:0006073 32 0.013
respiratory tube development GO:0030323 167 0.013
adult locomotory behavior GO:0008344 91 0.013
positive regulation of transmembrane transport GO:0034764 29 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
necroptotic process GO:0070266 21 0.013
regulation of membrane potential GO:0042391 192 0.013
sensory perception GO:0007600 245 0.012
nitrogen compound transport GO:0071705 271 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of cardiac muscle hypertrophy GO:0010611 13 0.012
neuron neuron synaptic transmission GO:0007270 69 0.012
calcium ion homeostasis GO:0055074 127 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
pallium development GO:0021543 120 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
lateral inhibition GO:0046331 1 0.012
amino acid uptake involved in synaptic transmission GO:0051933 3 0.012
l glutamate transport GO:0015813 16 0.012
locomotory behavior GO:0007626 195 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
olfactory learning GO:0008355 2 0.012
lung development GO:0030324 164 0.012
mitochondrion distribution GO:0048311 4 0.012
negative regulation of proteolysis GO:0045861 74 0.012
positive regulation of peptidase activity GO:0010952 49 0.012
regulation of exit from mitosis GO:0007096 1 0.012
iron coordination entity transport GO:1901678 5 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
regulation of actin filament based process GO:0032970 99 0.011
heme transport GO:0015886 2 0.011
regeneration GO:0031099 38 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.011
execution phase of apoptosis GO:0097194 19 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
fertilization GO:0009566 127 0.011
response to growth factor GO:0070848 198 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
skin development GO:0043588 220 0.011
cytoplasmic transport GO:0016482 234 0.011
somatic diversification of immunoglobulins GO:0016445 43 0.011
rna splicing via endonucleolytic cleavage and ligation GO:0000394 1 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of angiogenesis GO:0045765 81 0.011
cell growth GO:0016049 130 0.011
response to light stimulus GO:0009416 135 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
purine containing compound catabolic process GO:0072523 213 0.011
cellular chemical homeostasis GO:0055082 215 0.011
sperm motility GO:0030317 47 0.011
negative regulation of cell development GO:0010721 169 0.011
regulation of metal ion transport GO:0010959 106 0.011
endocytosis GO:0006897 168 0.011
response to steroid hormone GO:0048545 56 0.011
regulation of sarcomere organization GO:0060297 4 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
male anatomical structure morphogenesis GO:0090598 4 0.010
genitalia development GO:0048806 37 0.010
organelle assembly GO:0070925 177 0.010
anion transport GO:0006820 177 0.010
response to heat GO:0009408 27 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
nucleic acid transport GO:0050657 18 0.010
l amino acid transport GO:0015807 32 0.010
mapk cascade GO:0000165 281 0.010

Fkbp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.056
muscular disease DOID:0080000 0 0.056
disease of anatomical entity DOID:7 0 0.056
musculoskeletal system disease DOID:17 0 0.056
muscle tissue disease DOID:66 0 0.056
blood platelet disease DOID:2218 0 0.030
hemorrhagic disease DOID:2213 0 0.030
immune system disease DOID:2914 0 0.030
blood coagulation disease DOID:1247 0 0.030
hematopoietic system disease DOID:74 0 0.030
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012