Mus musculus

192 known processes

Dvl2

dishevelled 2, dsh homolog (Drosophila)

Dvl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 1.000
Mouse
muscular septum morphogenesis GO:0003150 4 1.000
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 1.000
Mouse
protein localization to microtubule cytoskeleton GO:0072698 8 1.000
Mouse
non canonical wnt signaling pathway GO:0035567 33 1.000
planar dichotomous subdivision of terminal units involved in lung branching morphogenesis GO:0060489 2 1.000
planar cell polarity pathway involved in axis elongation GO:0003402 4 1.000
regulation of establishment of planar polarity GO:0090175 28 1.000
establishment of planar polarity of embryonic epithelium GO:0042249 16 1.000
establishment of monopolar cell polarity GO:0061162 8 1.000
Fly
convergent extension involved in neural plate elongation GO:0022007 4 1.000
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 1.000
wnt signaling pathway planar cell polarity pathway GO:0060071 27 1.000
establishment of tissue polarity GO:0007164 28 1.000
establishment of planar polarity involved in neural tube closure GO:0090177 15 1.000
establishment of planar polarity GO:0001736 28 1.000
gonad morphogenesis GO:0035262 1 1.000
Worm
morphogenesis of a polarized epithelium GO:0001738 37 0.999
protein localization to microtubule GO:0035372 3 0.999
Mouse
regulation of cardioblast differentiation GO:0051890 3 0.999
Fly
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.999
convergent extension GO:0060026 14 0.998
skeletal muscle acetylcholine gated channel clustering GO:0071340 7 0.998
Mouse
cytoplasmic microtubule organization GO:0031122 14 0.998
Mouse
nonmotile primary cilium assembly GO:0035058 8 0.998
lateral sprouting involved in lung morphogenesis GO:0060490 2 0.998
neural plate morphogenesis GO:0001839 9 0.997
endodermal cell fate specification GO:0001714 4 0.997
Worm
regulation of heart induction GO:0090381 2 0.997
Fly
negative regulation of cell fate specification GO:0009996 4 0.997
Fly
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.997
positive regulation of jun kinase activity GO:0043507 30 0.997
neural plate development GO:0001840 12 0.997
dendrite self avoidance GO:0070593 2 0.997
cardiac cell fate specification GO:0060912 2 0.996
Fly
heart field specification GO:0003128 6 0.996
neural plate elongation GO:0014022 4 0.996
convergent extension involved in organogenesis GO:0060029 7 0.995
cilium assembly GO:0042384 81 0.995
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.994
lamellipodium organization GO:0097581 29 0.994
Fly
regulation of jnk cascade GO:0046328 62 0.993
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.993
Fly
jnk cascade GO:0007254 72 0.992
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.990
Fly
tube closure GO:0060606 91 0.989
retinal ganglion cell axon guidance GO:0031290 18 0.987
Fly
social behavior GO:0035176 21 0.986
Mouse
cell fate specification involved in pattern specification GO:0060573 11 0.985
Worm
regulation of canonical wnt signaling pathway GO:0060828 82 0.985
embryonic epithelial tube formation GO:0001838 130 0.981
regulation of stress activated mapk cascade GO:0032872 69 0.978
convergent extension involved in axis elongation GO:0060028 7 0.977
Zebrafish
canonical wnt signaling pathway GO:0060070 130 0.977
membranous septum morphogenesis GO:0003149 6 0.975
heart induction GO:0003129 2 0.974
Fly
cell migration involved in kidney development GO:0035787 3 0.974
establishment or maintenance of monopolar cell polarity GO:0061339 8 0.973
Fly
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.972
Fly
regulation of wnt signaling pathway GO:0030111 123 0.969
positive regulation of jnk cascade GO:0046330 46 0.968
positive regulation of mapk cascade GO:0043410 170 0.968
stress activated protein kinase signaling cascade GO:0031098 81 0.961
dichotomous subdivision of an epithelial terminal unit GO:0060600 11 0.958
neural tube formation GO:0001841 108 0.957
regulation of map kinase activity GO:0043405 120 0.948
morphogenesis of an epithelial sheet GO:0002011 27 0.947
positive regulation of stress activated mapk cascade GO:0032874 48 0.945
stress activated mapk cascade GO:0051403 80 0.943
primary neural tube formation GO:0014020 95 0.943
regulation of organ morphogenesis GO:2000027 144 0.943
endodermal cell fate commitment GO:0001711 12 0.938
Worm
regulation of jun kinase activity GO:0043506 40 0.937
positive regulation of transferase activity GO:0051347 167 0.935
motor neuron axon guidance GO:0008045 26 0.935
Fly
neural tube closure GO:0001843 90 0.933
negative chemotaxis GO:0050919 14 0.925
Fly
positive regulation of map kinase activity GO:0043406 84 0.924
regulation of protein serine threonine kinase activity GO:0071900 157 0.923
epithelial tube morphogenesis GO:0060562 303 0.923
stem cell development GO:0048864 219 0.919
Fly
development of primary female sexual characteristics GO:0046545 73 0.919
Fly
negative regulation of protein phosphorylation GO:0001933 126 0.918
Mouse
regulation of microtubule based process GO:0032886 52 0.918
Worm
mapk cascade GO:0000165 281 0.916
cochlea morphogenesis GO:0090103 22 0.915
regulation of actin filament based process GO:0032970 99 0.911
Fly
salivary gland development GO:0007431 37 0.909
Fly
regulation of actin cytoskeleton organization GO:0032956 84 0.908
Fly
segment specification GO:0007379 15 0.907
outflow tract septum morphogenesis GO:0003148 11 0.907
Mouse
regulation of mapk cascade GO:0043408 248 0.900
negative regulation of wnt signaling pathway GO:0030178 73 0.898
apical protein localization GO:0045176 7 0.898
epidermis morphogenesis GO:0048730 33 0.896
Worm Fly
spindle localization GO:0051653 22 0.891
Worm
positive regulation of wnt signaling pathway GO:0030177 45 0.887
ear morphogenesis GO:0042471 118 0.881
cilium morphogenesis GO:0060271 102 0.881
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 14 0.881
Fly
embryonic organ morphogenesis GO:0048562 276 0.880
cardiac septum morphogenesis GO:0060411 46 0.878
Mouse
regulation of non canonical wnt signaling pathway GO:2000050 12 0.878
regulation of cellular amino acid metabolic process GO:0006521 5 0.877
wnt signaling pathway GO:0016055 188 0.876
establishment of mitotic spindle localization GO:0040001 12 0.876
Worm
cellular amine metabolic process GO:0044106 44 0.875
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.867
regulation of transferase activity GO:0051338 263 0.865
regulation of protein tyrosine kinase activity GO:0061097 17 0.863
cochlea development GO:0090102 35 0.858
inner ear morphogenesis GO:0042472 101 0.856
epithelial tube formation GO:0072175 130 0.851
positive regulation of protein phosphorylation GO:0001934 242 0.847
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.841
regulation of kinase activity GO:0043549 249 0.839
regulation of stem cell differentiation GO:2000736 50 0.839
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.838
positive regulation of kinase activity GO:0033674 155 0.832
regulation of cellular ketone metabolic process GO:0010565 66 0.831
stem cell differentiation GO:0048863 268 0.827
Fly
cardiac septum development GO:0003279 59 0.825
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.825
negative regulation of phosphorus metabolic process GO:0010563 184 0.825
Mouse
wound healing GO:0042060 157 0.824
protein localization to cytoskeleton GO:0044380 9 0.819
Mouse
cellular ketone metabolic process GO:0042180 84 0.817
peptidyl tyrosine modification GO:0018212 145 0.811
peptidyl tyrosine phosphorylation GO:0018108 143 0.807
tube formation GO:0035148 140 0.803
positive regulation of neuron projection development GO:0010976 79 0.803
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.802
Mouse
digestive tract development GO:0048565 190 0.795
Worm
positive regulation of cellular amine metabolic process GO:0033240 5 0.795
establishment of epithelial cell polarity GO:0090162 10 0.790
Fly
stem cell maintenance GO:0019827 130 0.789
Fly
intraspecies interaction between organisms GO:0051703 21 0.788
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.786
Zebrafish Mouse Fly
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.785
actin filament bundle assembly GO:0051017 40 0.781
Fly
wnt signaling pathway involved in heart development GO:0003306 8 0.778
Fly
ras protein signal transduction GO:0007265 77 0.774
asymmetric protein localization GO:0008105 11 0.770
Worm
dichotomous subdivision of terminal units involved in lung branching GO:0060448 3 0.768
developmental induction GO:0031128 34 0.766
Fly
axon guidance GO:0007411 141 0.766
Mouse Fly
specification of organ identity GO:0010092 30 0.764
morphogenesis of embryonic epithelium GO:0016331 159 0.762
cell recognition GO:0008037 83 0.759
Fly
negative regulation of phosphorylation GO:0042326 166 0.758
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.752
Mouse
neural tube development GO:0021915 160 0.748
inner ear receptor stereocilium organization GO:0060122 23 0.748
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.743
positive regulation of protein kinase activity GO:0045860 144 0.740
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.739
Worm
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.737
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 10 0.734
ear development GO:0043583 200 0.734
actin cytoskeleton organization GO:0030036 220 0.734
Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.733
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.728
Mouse
somatic stem cell maintenance GO:0035019 47 0.716
Fly
cerebral cortex radially oriented cell migration GO:0021799 31 0.711
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.704
mitotic cell cycle process GO:1903047 159 0.701
Worm
establishment of apical basal cell polarity GO:0035089 7 0.695
Fly
regulation of cellular response to stress GO:0080135 159 0.694
axis elongation GO:0003401 30 0.685
Zebrafish
establishment of spindle orientation GO:0051294 15 0.683
Worm
inner ear receptor cell differentiation GO:0060113 61 0.682
establishment or maintenance of cell polarity GO:0007163 86 0.680
Worm Fly
forebrain ventricular zone progenitor cell division GO:0021869 6 0.680
cell division GO:0051301 120 0.672
Worm
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.665
Fly
regulation of mitotic cell cycle GO:0007346 126 0.664
Worm
branching morphogenesis of an epithelial tube GO:0048754 159 0.647
organelle assembly GO:0070925 177 0.639
positive regulation of cell projection organization GO:0031346 95 0.638
Mouse
mechanoreceptor differentiation GO:0042490 67 0.631
respiratory tube development GO:0030323 167 0.627
positive regulation of nervous system development GO:0051962 221 0.626
Mouse
digestive system development GO:0055123 200 0.622
Worm
regulation of protein binding GO:0043393 60 0.613
regulation of embryonic development GO:0045995 71 0.612
microtubule cytoskeleton organization GO:0000226 157 0.604
Mouse Worm
cardiac chamber development GO:0003205 108 0.599
Mouse
chemotaxis GO:0006935 247 0.598
Mouse Fly
positive regulation of proteolysis GO:0045862 85 0.592
ventricular septum development GO:0003281 42 0.589
protein localization to nucleus GO:0034504 121 0.587
establishment of spindle localization GO:0051293 19 0.572
Worm
asymmetric cell division GO:0008356 8 0.572
Worm
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.570
ventricular septum morphogenesis GO:0060412 27 0.569
dendrite development GO:0016358 115 0.565
Mouse
female gonad development GO:0008585 71 0.563
Fly
neurotransmitter transport GO:0006836 76 0.560
Mouse
rho protein signal transduction GO:0007266 32 0.558
epidermis development GO:0008544 187 0.558
Worm Fly
negative regulation of transferase activity GO:0051348 85 0.554
organelle localization GO:0051640 179 0.541
Worm
regionalization GO:0003002 337 0.526
formation of primary germ layer GO:0001704 77 0.524
Worm
positive regulation of protein catabolic process GO:0045732 60 0.512
protein localization to membrane GO:0072657 108 0.511
Mouse
orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis GO:0060488 2 0.508
segmentation GO:0035282 93 0.501
membrane organization GO:0061024 245 0.487
Mouse
regulation of proteolysis GO:0030162 164 0.485
regulation of protein kinase activity GO:0045859 232 0.482
regulation of actin filament bundle assembly GO:0032231 18 0.468
Fly
regulation of cytoskeleton organization GO:0051493 122 0.466
Worm Fly
regulation of neuron projection development GO:0010975 169 0.465
Mouse
regulation of heart morphogenesis GO:2000826 22 0.452
Fly
sensory organ morphogenesis GO:0090596 242 0.447
muscle tissue morphogenesis GO:0060415 53 0.443
cell fate commitment GO:0045165 210 0.440
Worm Fly
neuron projection extension GO:1990138 64 0.428
Mouse Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.420
Mouse
neuron projection guidance GO:0097485 141 0.419
Mouse Fly
salivary gland morphogenesis GO:0007435 33 0.417
Fly
negative regulation of cell fate commitment GO:0010454 8 0.397
Fly
telencephalon cell migration GO:0022029 55 0.396
regulation of neuron differentiation GO:0045664 281 0.395
Mouse
postsynaptic membrane organization GO:0001941 18 0.393
Mouse
negative regulation of notch signaling pathway GO:0045746 14 0.393
Fly
regulation of cellular protein catabolic process GO:1903362 61 0.391
multicellular organismal reproductive behavior GO:0033057 23 0.391
Worm
regulation of neurotransmitter levels GO:0001505 87 0.390
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.387
Fly
regulation of proteasomal protein catabolic process GO:0061136 46 0.386
cytoplasmic transport GO:0016482 234 0.386
ubiquitin dependent protein catabolic process GO:0006511 129 0.377
regulation of organelle organization GO:0033043 289 0.371
Worm Fly
gastrulation GO:0007369 116 0.363
Worm
positive regulation of protein tyrosine kinase activity GO:0061098 10 0.362
cardiocyte differentiation GO:0035051 87 0.362
Fly
embryonic heart tube development GO:0035050 65 0.360
microtubule based process GO:0007017 236 0.355
Mouse Worm
regulation of cardiac cell fate specification GO:2000043 1 0.351
Fly
heart morphogenesis GO:0003007 178 0.350
negative regulation of stem cell differentiation GO:2000737 14 0.348
Fly
regulation of cell cycle process GO:0010564 160 0.344
Worm
protein catabolic process GO:0030163 221 0.341
forebrain development GO:0030900 302 0.338
glomerulus development GO:0032835 40 0.334
positive regulation of cellular protein catabolic process GO:1903364 34 0.334
synapse organization GO:0050808 125 0.331
Mouse
digestive tract morphogenesis GO:0048546 147 0.330
Worm
macromolecule catabolic process GO:0009057 281 0.315
oogenesis GO:0048477 56 0.314
Fly
establishment of body hair or bristle planar orientation GO:0048104 2 0.314
endodermal cell differentiation GO:0035987 14 0.306
Worm
amine metabolic process GO:0009308 45 0.305
regulation of cellular catabolic process GO:0031329 242 0.304
skin development GO:0043588 220 0.301
Worm Fly
genitalia development GO:0048806 37 0.291
Worm
cell cell junction organization GO:0045216 72 0.291
neuron migration GO:0001764 122 0.287
Worm
morphogenesis of a branching structure GO:0001763 203 0.286
regulation of cell fate specification GO:0042659 10 0.286
Fly
forebrain cell migration GO:0021885 58 0.284
cell fate specification GO:0001708 72 0.281
Worm Fly
regulation of protein localization GO:0032880 231 0.280
Worm
small gtpase mediated signal transduction GO:0007264 97 0.280
negative regulation of molecular function GO:0044092 258 0.273
filopodium assembly GO:0046847 19 0.271
Fly
actin filament organization GO:0007015 113 0.270
Fly
regulation of cell cycle GO:0051726 281 0.259
Worm
reproductive behavior GO:0019098 32 0.259
Worm
positive regulation of cell development GO:0010720 237 0.255
Mouse
establishment of epithelial cell apical basal polarity GO:0045198 5 0.250
Fly
cell fate commitment involved in pattern specification GO:0060581 14 0.249
Worm
outflow tract morphogenesis GO:0003151 53 0.248
cellular amino acid metabolic process GO:0006520 103 0.244
positive regulation of protein modification process GO:0031401 299 0.227
cardiac ventricle development GO:0003231 83 0.218
cellular protein catabolic process GO:0044257 155 0.215
peptidyl amino acid modification GO:0018193 336 0.208
t cell proliferation GO:0042098 120 0.205
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.205
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.203
modification dependent macromolecule catabolic process GO:0043632 133 0.199
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.199
mitotic cell cycle GO:0000278 195 0.194
Worm
regulation of cell projection organization GO:0031344 206 0.183
Mouse
positive regulation of non canonical wnt signaling pathway GO:2000052 6 0.182
development of primary sexual characteristics GO:0045137 143 0.181
Worm Fly
lung morphogenesis GO:0060425 50 0.176
regulation of protein targeting GO:1903533 61 0.175
kidney development GO:0001822 213 0.174
negative regulation of intracellular signal transduction GO:1902532 167 0.167
cell fate determination GO:0001709 32 0.166
Worm
neuromuscular process GO:0050905 99 0.165
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.161
spindle organization GO:0007051 28 0.160
Worm
cilium movement GO:0003341 28 0.159
negative regulation of cell proliferation GO:0008285 296 0.158
renal system development GO:0072001 225 0.156
regulation of binding GO:0051098 111 0.153
negative regulation of kinase activity GO:0033673 81 0.150
negative regulation of protein modification process GO:0031400 163 0.148
Mouse
regulation of lymphocyte activation GO:0051249 240 0.148
modification dependent protein catabolic process GO:0019941 133 0.147
female gamete generation GO:0007292 74 0.141
Fly
protein import into nucleus GO:0006606 95 0.140
neuron recognition GO:0008038 25 0.139
Fly
proteasomal protein catabolic process GO:0010498 98 0.135
exocrine system development GO:0035272 45 0.131
Fly
multi multicellular organism process GO:0044706 109 0.131
Worm
positive regulation of cellular catabolic process GO:0031331 148 0.129
regulation of peptidyl serine phosphorylation GO:0033135 39 0.124
ribonucleotide catabolic process GO:0009261 208 0.124
cell growth GO:0016049 130 0.124
Mouse Fly
developmental cell growth GO:0048588 84 0.123
Mouse Fly
gonad development GO:0008406 141 0.122
Worm Fly
negative regulation of lymphocyte activation GO:0051250 91 0.122
establishment of mitotic spindle orientation GO:0000132 12 0.122
Worm
regulation of establishment or maintenance of cell polarity GO:0032878 10 0.122
Worm
germ cell development GO:0007281 185 0.121
Fly
cell adhesion GO:0007155 329 0.114
gland development GO:0048732 330 0.108
Fly
positive regulation of cell death GO:0010942 224 0.107
establishment of body hair planar orientation GO:0048105 2 0.106
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 5 0.106
regulation of fat cell differentiation GO:0045598 81 0.103
negative regulation of mapk cascade GO:0043409 65 0.103
establishment of organelle localization GO:0051656 122 0.102
Worm
meiotic cell cycle GO:0051321 122 0.101
lipid localization GO:0010876 126 0.100
purine nucleoside triphosphate metabolic process GO:0009144 226 0.099
female sex differentiation GO:0046660 84 0.098
Fly
regulation of protein import into nucleus GO:0042306 52 0.098
nucleoside triphosphate metabolic process GO:0009141 230 0.097
cellular homeostasis GO:0019725 240 0.097
respiratory system development GO:0060541 190 0.096
Fly
glycosyl compound metabolic process GO:1901657 246 0.094
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.093
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.088
positive regulation of rho gtpase activity GO:0032321 41 0.087
nucleoside catabolic process GO:0009164 206 0.084
regulation of cell fate commitment GO:0010453 19 0.084
Fly
negative regulation of leukocyte proliferation GO:0070664 46 0.083
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.083
lateral sprouting from an epithelium GO:0060601 13 0.081
regulation of protein catabolic process GO:0042176 108 0.080
embryonic heart tube morphogenesis GO:0003143 51 0.080
skeletal system development GO:0001501 356 0.079
purine ribonucleoside catabolic process GO:0046130 205 0.078
carbohydrate derivative catabolic process GO:1901136 231 0.078
negative regulation of catenin import into nucleus GO:0035414 2 0.077
neurotransmitter secretion GO:0007269 62 0.077
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.077
regulation of t cell anergy GO:0002667 4 0.076
cerebral cortex cell migration GO:0021795 44 0.075
guanosine containing compound metabolic process GO:1901068 144 0.074
hair cycle GO:0042633 90 0.073
cardioblast differentiation GO:0010002 13 0.071
Fly
kidney morphogenesis GO:0060993 83 0.071
epithelial cell morphogenesis GO:0003382 41 0.070
regulation of protein localization to nucleus GO:1900180 60 0.069
cellular response to lipid GO:0071396 145 0.068
protein ubiquitination GO:0016567 171 0.068
t cell anergy GO:0002870 4 0.067
regulation of nucleocytoplasmic transport GO:0046822 73 0.067
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.067
regulation of ion transmembrane transport GO:0034765 119 0.066
lymphocyte proliferation GO:0046651 164 0.066
regulation of cell activation GO:0050865 289 0.066
regulation of lymphocyte anergy GO:0002911 4 0.066
negative regulation of bmp signaling pathway GO:0030514 35 0.066
intracellular protein transport GO:0006886 204 0.066
positive regulation of programmed cell death GO:0043068 218 0.064
regulation of catenin import into nucleus GO:0035412 5 0.064
cellular nitrogen compound catabolic process GO:0044270 280 0.062
negative regulation of growth GO:0045926 99 0.062
positive regulation of lymphocyte anergy GO:0002913 4 0.061
negative regulation of t cell activation GO:0050868 65 0.061
lipid transport GO:0006869 98 0.061
regulation of cell adhesion GO:0030155 154 0.059
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.058
phagocytosis GO:0006909 66 0.058
adaptive immune response GO:0002250 155 0.058
protein localization to organelle GO:0033365 185 0.057
Mouse
nephron development GO:0072006 109 0.057
cellular response to dna damage stimulus GO:0006974 207 0.055
lung development GO:0030324 164 0.055
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.055
skin morphogenesis GO:0043589 38 0.054
Worm Fly
nuclear division GO:0000280 158 0.054
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.054
lymphocyte differentiation GO:0030098 242 0.054
regulation of t cell activation GO:0050863 170 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.052
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.052
glycosyl compound catabolic process GO:1901658 206 0.051
meiotic nuclear division GO:0007126 115 0.051
dna metabolic process GO:0006259 303 0.049
negative regulation of cell activation GO:0050866 111 0.048
positive regulation of hydrolase activity GO:0051345 148 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.047
cellular response to organic cyclic compound GO:0071407 87 0.047
dna repair GO:0006281 107 0.047
nucleotide metabolic process GO:0009117 332 0.046
response to insulin GO:0032868 100 0.045
monocarboxylic acid metabolic process GO:0032787 191 0.045
regulation of defense response GO:0031347 233 0.044
cellular response to retinoic acid GO:0071300 25 0.042
maintenance of location GO:0051235 89 0.040
morphogenesis of a branching epithelium GO:0061138 193 0.040
purine nucleotide catabolic process GO:0006195 211 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
gtp catabolic process GO:0006184 143 0.038
regulation of nucleotide catabolic process GO:0030811 122 0.038
cellularization GO:0007349 1 0.038
positive regulation of growth GO:0045927 104 0.038
regulation of intracellular protein transport GO:0033157 82 0.037
hair follicle development GO:0001942 85 0.037
protein targeting GO:0006605 143 0.037
notch signaling pathway GO:0007219 71 0.037
Fly
organ induction GO:0001759 21 0.037
Fly
negative regulation of map kinase activity GO:0043407 34 0.037
regulation of cytoplasmic transport GO:1903649 112 0.036
regulation of lymphocyte proliferation GO:0050670 117 0.036
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.036
protein modification by small protein removal GO:0070646 21 0.036
hematopoietic progenitor cell differentiation GO:0002244 143 0.035
regulation of purine nucleotide metabolic process GO:1900542 169 0.035
placenta development GO:0001890 140 0.035
positive regulation of protein localization to nucleus GO:1900182 30 0.035
cerebellum development GO:0021549 77 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.035
intracellular receptor signaling pathway GO:0030522 74 0.034
positive regulation of gtp catabolic process GO:0033126 85 0.034
immune effector process GO:0002252 321 0.033
regulation of rho protein signal transduction GO:0035023 71 0.033
leukocyte differentiation GO:0002521 342 0.033
innate immune response GO:0045087 157 0.033
liver development GO:0001889 66 0.033
nucleotide catabolic process GO:0009166 217 0.032
determination of heart left right asymmetry GO:0061371 48 0.032
regulation of mitotic cell cycle phase transition GO:1901990 73 0.032
response to organonitrogen compound GO:0010243 246 0.032
heterocycle catabolic process GO:0046700 280 0.032
cellular response to peptide hormone stimulus GO:0071375 92 0.032
positive regulation of protein ubiquitination GO:0031398 27 0.032
anatomical structure homeostasis GO:0060249 145 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
cation transport GO:0006812 399 0.030
negative regulation of immune system process GO:0002683 209 0.030
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.030
microglia development GO:0014005 2 0.030
carbohydrate metabolic process GO:0005975 230 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
osteoclast differentiation GO:0030316 62 0.029
adult behavior GO:0030534 135 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.028
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.028
protein import GO:0017038 101 0.028
negative regulation of binding GO:0051100 39 0.028
response to osmotic stress GO:0006970 21 0.028
epithelial cell proliferation GO:0050673 174 0.028
negative regulation of cell cycle GO:0045786 123 0.027
neuron death GO:0070997 154 0.027
peptidyl serine phosphorylation GO:0018105 74 0.027
mammary gland duct morphogenesis GO:0060603 38 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
negative regulation of nervous system development GO:0051961 156 0.027
protein polyubiquitination GO:0000209 33 0.027
negative regulation of cellular component organization GO:0051129 194 0.026
single organism nuclear import GO:1902593 95 0.026
cell proliferation in forebrain GO:0021846 30 0.026
multi organism behavior GO:0051705 62 0.026
Mouse Worm
engulfment of apoptotic cell GO:0043652 3 0.026
compound eye development GO:0048749 1 0.026
Fly
multi organism reproductive behavior GO:0044705 29 0.026
Worm
negative regulation of defense response GO:0031348 77 0.026
regulation of cell migration GO:0030334 219 0.026
cellular chemical homeostasis GO:0055082 215 0.026
guanosine containing compound catabolic process GO:1901069 144 0.025
regulation of t cell proliferation GO:0042129 92 0.025
determination of left right symmetry GO:0007368 80 0.025
regulation of endopeptidase activity GO:0052548 89 0.025
negative regulation of protein binding GO:0032091 17 0.025
response to acid chemical GO:0001101 111 0.025
single organism cell adhesion GO:0098602 156 0.025
defense response to virus GO:0051607 68 0.025
cytokine production GO:0001816 319 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.025
lymphocyte anergy GO:0002249 4 0.024
reactive oxygen species metabolic process GO:0072593 84 0.024
regulation of ion transport GO:0043269 215 0.024
hindgut morphogenesis GO:0007442 7 0.024
regulation of notch signaling pathway GO:0008593 35 0.024
Fly

Dvl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.033
gastrointestinal system cancer DOID:3119 0 0.024
cancer DOID:162 0 0.024
organ system cancer DOID:0050686 0 0.024