Mus musculus

0 known processes

Scn2b

sodium channel, voltage-gated, type II, beta

(Aliases: 2810451E09Rik,MGC116602,AI840361,Gm183)

Scn2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane organization GO:0061024 245 0.116
synaptic transmission GO:0007268 329 0.106
cation transport GO:0006812 399 0.097
Human Mouse Rat
locomotory behavior GO:0007626 195 0.086
cellular amino acid metabolic process GO:0006520 103 0.082
regulation of secretion GO:0051046 274 0.077
regulation of cellular amino acid metabolic process GO:0006521 5 0.076
regulation of secretion by cell GO:1903530 249 0.073
cation transmembrane transport GO:0098655 266 0.069
Human Mouse Rat
ion transmembrane transport GO:0034220 361 0.065
Human Mouse Rat
synaptic vesicle localization GO:0097479 59 0.063
amine metabolic process GO:0009308 45 0.061
regulation of ion transport GO:0043269 215 0.058
Human Mouse Rat
cation homeostasis GO:0055080 212 0.057
regulation of membrane potential GO:0042391 192 0.055
Human
regulation of transmembrane transport GO:0034762 128 0.054
Human Mouse Rat
protein localization to membrane GO:0072657 108 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
divalent metal ion transport GO:0070838 172 0.049
transmembrane transport GO:0055085 412 0.049
Human Mouse Rat
nitrogen compound transport GO:0071705 271 0.046
cellular amine metabolic process GO:0044106 44 0.045
g protein coupled receptor signaling pathway GO:0007186 243 0.044
cellular ketone metabolic process GO:0042180 84 0.044
divalent inorganic cation transport GO:0072511 178 0.044
metal ion homeostasis GO:0055065 189 0.043
positive regulation of secretion GO:0051047 130 0.043
immune effector process GO:0002252 321 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.040
neuronal action potential GO:0019228 54 0.040
synapse organization GO:0050808 125 0.039
apoptotic signaling pathway GO:0097190 306 0.039
cellular lipid metabolic process GO:0044255 323 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
transmission of nerve impulse GO:0019226 76 0.037
exocytosis GO:0006887 121 0.037
calcium ion transport GO:0006816 159 0.036
regulation of metal ion transport GO:0010959 106 0.036
Human
cellular homeostasis GO:0019725 240 0.036
regulation of cellular component biogenesis GO:0044087 181 0.034
establishment of vesicle localization GO:0051650 81 0.034
regulation of organelle organization GO:0033043 289 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
male gamete generation GO:0048232 285 0.034
regulation of neurotransmitter levels GO:0001505 87 0.034
endomembrane system organization GO:0010256 147 0.034
positive regulation of secretion by cell GO:1903532 114 0.034
cellular metal ion homeostasis GO:0006875 151 0.033
mapk cascade GO:0000165 281 0.032
negative regulation of cell proliferation GO:0008285 296 0.032
lymphocyte proliferation GO:0046651 164 0.032
adult locomotory behavior GO:0008344 91 0.032
regulation of transferase activity GO:0051338 263 0.032
neuron neuron synaptic transmission GO:0007270 69 0.031
inorganic cation transmembrane transport GO:0098662 207 0.031
Human Mouse Rat
learning or memory GO:0007611 148 0.031
synaptic vesicle transport GO:0048489 57 0.030
cellular divalent inorganic cation homeostasis GO:0072503 127 0.030
macromolecule catabolic process GO:0009057 281 0.030
muscle cell differentiation GO:0042692 261 0.030
regulation of neuron differentiation GO:0045664 281 0.029
cellular chemical homeostasis GO:0055082 215 0.029
endocytosis GO:0006897 168 0.029
cognition GO:0050890 149 0.029
establishment of synaptic vesicle localization GO:0097480 57 0.029
maintenance of location GO:0051235 89 0.028
urogenital system development GO:0001655 261 0.028
neurotransmitter secretion GO:0007269 62 0.028
oxidation reduction process GO:0055114 342 0.028
neurotransmitter transport GO:0006836 76 0.028
multicellular organismal signaling GO:0035637 91 0.027
Human
organelle localization GO:0051640 179 0.026
leukocyte proliferation GO:0070661 172 0.026
regulation of cytokine production GO:0001817 266 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
fat cell differentiation GO:0045444 160 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
leukocyte differentiation GO:0002521 342 0.025
Mouse
regulation of cell migration GO:0030334 219 0.025
adult behavior GO:0030534 135 0.025
cytokine production GO:0001816 319 0.025
dna metabolic process GO:0006259 303 0.025
myeloid cell differentiation GO:0030099 233 0.025
positive regulation of cytokine production GO:0001819 174 0.025
striated muscle tissue development GO:0014706 293 0.024
single organismal cell cell adhesion GO:0016337 131 0.024
Mouse
regulation of anatomical structure size GO:0090066 178 0.024
cellular ion homeostasis GO:0006873 165 0.024
positive regulation of transferase activity GO:0051347 167 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
muscle tissue development GO:0060537 308 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
fertilization GO:0009566 127 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
vesicle localization GO:0051648 86 0.024
positive regulation of cell death GO:0010942 224 0.023
glycoprotein metabolic process GO:0009100 116 0.023
positive regulation of cell projection organization GO:0031346 95 0.023
t cell activation GO:0042110 289 0.023
Mouse
regulation of system process GO:0044057 200 0.023
Human
peptidyl amino acid modification GO:0018193 336 0.023
leukocyte mediated immunity GO:0002443 174 0.023
intracellular protein transport GO:0006886 204 0.023
lymphocyte differentiation GO:0030098 242 0.023
Mouse
positive regulation of cell development GO:0010720 237 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
cell adhesion GO:0007155 329 0.023
Mouse
positive regulation of protein modification process GO:0031401 299 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
spermatogenesis GO:0007283 284 0.022
homeostasis of number of cells GO:0048872 210 0.022
development of primary sexual characteristics GO:0045137 143 0.022
oocyte construction GO:0007308 2 0.022
plasma membrane organization GO:0007009 90 0.022
spermatid differentiation GO:0048515 115 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
positive regulation of ion transport GO:0043270 65 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
Human Mouse Rat
positive regulation of nervous system development GO:0051962 221 0.021
feeding behavior GO:0007631 62 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
wnt signaling pathway GO:0016055 188 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
membrane depolarization GO:0051899 64 0.021
Human
regulation of epithelial cell proliferation GO:0050678 141 0.021
Mouse
ras protein signal transduction GO:0007265 77 0.021
regulation of neuron projection development GO:0010975 169 0.020
anatomical structure homeostasis GO:0060249 145 0.020
cellular response to lipid GO:0071396 145 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
single organism cell adhesion GO:0098602 156 0.020
Mouse
spermatid development GO:0007286 108 0.020
regulation of cell motility GO:2000145 236 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
regulation of cell projection organization GO:0031344 206 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
establishment of organelle localization GO:0051656 122 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
microtubule based process GO:0007017 236 0.019
muscle contraction GO:0006936 101 0.019
Human
positive regulation of protein kinase activity GO:0045860 144 0.019
nucleotide metabolic process GO:0009117 332 0.019
germ cell development GO:0007281 185 0.019
regulation of protein transport GO:0051223 163 0.019
protein catabolic process GO:0030163 221 0.019
calcium ion transmembrane transport GO:0070588 85 0.019
epidermis development GO:0008544 187 0.019
protein modification by small protein conjugation GO:0032446 187 0.018
immune response regulating signaling pathway GO:0002764 125 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
calcium ion homeostasis GO:0055074 127 0.018
regulation of protein localization GO:0032880 231 0.018
sensory perception GO:0007600 245 0.018
regulation of protein kinase activity GO:0045859 232 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
forebrain development GO:0030900 302 0.018
heterocycle catabolic process GO:0046700 280 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
response to organonitrogen compound GO:0010243 246 0.018
glial cell differentiation GO:0010001 131 0.018
positive regulation of kinase activity GO:0033674 155 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
purine containing compound metabolic process GO:0072521 311 0.018
defecation GO:0030421 1 0.018
gliogenesis GO:0042063 141 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
protein secretion GO:0009306 111 0.018
axon ensheathment GO:0008366 76 0.018
protein localization to organelle GO:0033365 185 0.018
sensory perception of mechanical stimulus GO:0050954 107 0.017
negative regulation of immune system process GO:0002683 209 0.017
innate immune response GO:0045087 157 0.017
ear development GO:0043583 200 0.017
myotube differentiation GO:0014902 105 0.017
adaptive immune response GO:0002250 155 0.017
peptidyl serine modification GO:0018209 83 0.017
regulation of feeding behavior GO:0060259 3 0.017
compound eye development GO:0048749 1 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
negative regulation of cell development GO:0010721 169 0.017
circulatory system process GO:0003013 197 0.017
Human
positive regulation of neuron differentiation GO:0045666 141 0.017
regulation of lymphocyte proliferation GO:0050670 117 0.017
protein maturation GO:0051604 176 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
regulation of hormone levels GO:0010817 211 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
protein ubiquitination GO:0016567 171 0.016
cytoplasmic transport GO:0016482 234 0.016
organic acid transport GO:0015849 101 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
action potential GO:0001508 78 0.016
Human
regulation of hydrolase activity GO:0051336 246 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
mitochondrion organization GO:0007005 134 0.016
cell activation involved in immune response GO:0002263 126 0.016
regulation of mapk cascade GO:0043408 248 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
Human Mouse Rat
negative regulation of nervous system development GO:0051961 156 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
fatty acid metabolic process GO:0006631 121 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
regulation of kinase activity GO:0043549 249 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
regulation of cell activation GO:0050865 289 0.016
glial cell development GO:0021782 54 0.016
activation of immune response GO:0002253 138 0.016
regulation of protein secretion GO:0050708 82 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
response to radiation GO:0009314 165 0.016
regulation of transporter activity GO:0032409 57 0.016
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.015
male genitalia morphogenesis GO:0048808 4 0.015
camera type eye development GO:0043010 266 0.015
regulation of cell cycle GO:0051726 281 0.015
cell type specific apoptotic process GO:0097285 268 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
organelle assembly GO:0070925 177 0.015
cytokine secretion GO:0050663 72 0.015
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.015
epithelial cell proliferation GO:0050673 174 0.015
Mouse
negative regulation of protein modification process GO:0031400 163 0.015
regulation of calcium ion transport GO:0051924 69 0.015
response to peptide GO:1901652 136 0.015
response to organic cyclic compound GO:0014070 198 0.015
regulation of ion transmembrane transporter activity GO:0032412 54 0.015
Human
ribonucleoside metabolic process GO:0009119 245 0.015
sequestering of metal ion GO:0051238 19 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
b cell activation GO:0042113 161 0.015
carbohydrate transport GO:0008643 62 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
telencephalon development GO:0021537 186 0.015
nucleoside metabolic process GO:0009116 246 0.015
organic anion transport GO:0015711 137 0.015
negative regulation of secretion GO:0051048 61 0.015
protein targeting GO:0006605 143 0.015
regulation of exocytosis GO:0017157 61 0.014
sequestering of calcium ion GO:0051208 18 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
amino acid transport GO:0006865 61 0.014
organelle fission GO:0048285 170 0.014
oocyte axis specification GO:0007309 2 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
sulfur compound metabolic process GO:0006790 100 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
sensory perception of pain GO:0019233 47 0.014
positive regulation of protein secretion GO:0050714 52 0.014
sodium ion transport GO:0006814 73 0.014
Human Mouse Rat
chemotaxis GO:0006935 247 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of long term synaptic depression GO:1900452 3 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
t cell proliferation GO:0042098 120 0.014
regulation of synaptic plasticity GO:0048167 87 0.014
regulation of homeostatic process GO:0032844 182 0.014
Human
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
memory GO:0007613 58 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
positive regulation of organelle organization GO:0010638 128 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
skeletal system development GO:0001501 356 0.013
muscle cell development GO:0055001 133 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
cell division GO:0051301 120 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
regulation of response to wounding GO:1903034 189 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
multi multicellular organism process GO:0044706 109 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
regulation of defense response GO:0031347 233 0.013
protein processing GO:0016485 163 0.013
amide transport GO:0042886 138 0.013
muscle system process GO:0003012 141 0.013
Human
nucleoside catabolic process GO:0009164 206 0.013
negative regulation of molecular function GO:0044092 258 0.013
anion transport GO:0006820 177 0.013
neuromuscular process GO:0050905 99 0.013
circadian rhythm GO:0007623 114 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
skeletal muscle organ development GO:0060538 163 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
defense response to other organism GO:0098542 197 0.013
regulation of cell adhesion GO:0030155 154 0.013
positive regulation of immune effector process GO:0002699 107 0.013
axonogenesis GO:0007409 274 0.013
potassium ion homeostasis GO:0055075 4 0.013
regulation of cytokine secretion GO:0050707 61 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.012
rho protein signal transduction GO:0007266 32 0.012
heart process GO:0003015 94 0.012
Human
ensheathment of neurons GO:0007272 76 0.012
carbohydrate metabolic process GO:0005975 230 0.012
myelination GO:0042552 74 0.012
ameboidal type cell migration GO:0001667 128 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
intracellular mrna localization GO:0008298 4 0.012
skin development GO:0043588 220 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
cytokine metabolic process GO:0042107 71 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.012
regulation of t cell activation GO:0050863 170 0.012
protein localization to juxtaparanode region of axon GO:0071205 4 0.012
response to acid chemical GO:0001101 111 0.012
cell junction organization GO:0034330 77 0.012
Mouse
male gonad development GO:0008584 88 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
regulation of innate immune response GO:0045088 91 0.012
positive regulation of protein transport GO:0051222 93 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
sensory perception of sound GO:0007605 97 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
protein kinase b signaling GO:0043491 74 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
rhythmic process GO:0048511 174 0.012
angiogenesis GO:0001525 201 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
b cell differentiation GO:0030183 78 0.012
nuclear division GO:0000280 158 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
single fertilization GO:0007338 82 0.012
nucleotide catabolic process GO:0009166 217 0.012
regulation of blood pressure GO:0008217 93 0.011
aromatic compound catabolic process GO:0019439 286 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
response to peptide hormone GO:0043434 127 0.011
regulation of cellular response to stress GO:0080135 159 0.011
t cell differentiation GO:0030217 174 0.011
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
microglial cell activation GO:0001774 3 0.011
stem cell differentiation GO:0048863 268 0.011
renal system development GO:0072001 225 0.011
sulfur compound biosynthetic process GO:0044272 37 0.011
protein localization to plasma membrane GO:0072659 57 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
response to light stimulus GO:0009416 135 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
synapse assembly GO:0007416 56 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
positive regulation of cell activation GO:0050867 158 0.011
lipid localization GO:0010876 126 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
inter male aggressive behavior GO:0002121 3 0.011
phospholipid metabolic process GO:0006644 87 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
positive regulation of transmembrane transport GO:0034764 29 0.011
cell maturation GO:0048469 127 0.011
pole plasm assembly GO:0007315 2 0.011
organophosphate catabolic process GO:0046434 232 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
adult walking behavior GO:0007628 41 0.011
regulation of chemotaxis GO:0050920 53 0.011
response to extracellular stimulus GO:0009991 127 0.011
small molecule biosynthetic process GO:0044283 132 0.011
mitotic cytokinesis GO:0000281 4 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
dephosphorylation GO:0016311 129 0.011
male anatomical structure morphogenesis GO:0090598 4 0.010
negative regulation of organelle organization GO:0010639 90 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
regulation of cellular component size GO:0032535 121 0.010
actin cytoskeleton organization GO:0030036 220 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
response to lipopolysaccharide GO:0032496 128 0.010
immune response activating signal transduction GO:0002757 116 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
gland development GO:0048732 330 0.010
peptide secretion GO:0002790 114 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
response to transforming growth factor beta GO:0071559 88 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
lipid biosynthetic process GO:0008610 179 0.010
response to steroid hormone GO:0048545 56 0.010
lysosome organization GO:0007040 21 0.010
engulfment of apoptotic cell GO:0043652 3 0.010

Scn2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of anatomical entity DOID:7 0 0.018
Human
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.017