Mus musculus

74 known processes

Trim63

tripartite motif-containing 63

(Aliases: MuRF1,RF1,Rnf28)

Trim63 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inactivity GO:0014854 4 0.932
response to muscle inactivity GO:0014870 4 0.859
muscle system process GO:0003012 141 0.821
Rat
response to muscle inactivity involved in regulation of muscle adaptation GO:0014877 4 0.774
muscle adaptation GO:0043500 39 0.759
Rat
response to denervation involved in regulation of muscle adaptation GO:0014894 4 0.535
regulation of muscle adaptation GO:0043502 31 0.506
negative regulation of protein complex disassembly GO:0043242 22 0.397
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.386
negative regulation of protein depolymerization GO:1901880 21 0.373
Mouse
cellular protein catabolic process GO:0044257 155 0.362
negative regulation of microtubule depolymerization GO:0007026 13 0.356
Mouse
microtubule polymerization or depolymerization GO:0031109 26 0.341
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.320
regulation of protein complex disassembly GO:0043244 28 0.312
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.302
modification dependent protein catabolic process GO:0019941 133 0.300
ubiquitin dependent protein catabolic process GO:0006511 129 0.294
regulation of microtubule depolymerization GO:0031114 13 0.282
Mouse
response to stimulus involved in regulation of muscle adaptation GO:0014874 6 0.273
macromolecule catabolic process GO:0009057 281 0.261
cellular macromolecule catabolic process GO:0044265 206 0.260
microtubule depolymerization GO:0007019 15 0.257
Mouse
proteasomal protein catabolic process GO:0010498 98 0.257
protein depolymerization GO:0051261 34 0.254
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.241
protein ubiquitination GO:0016567 171 0.236
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.231
Mouse
protein complex disassembly GO:0043241 40 0.228
Mouse
actin cytoskeleton organization GO:0030036 220 0.209
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.206
Mouse
protein catabolic process GO:0030163 221 0.193
cellular response to glucocorticoid stimulus GO:0071385 13 0.187
protein modification by small protein conjugation GO:0032446 187 0.182
regulation of microtubule based process GO:0032886 52 0.178
Mouse
muscle contraction GO:0006936 101 0.177
Rat
cellular response to lipid GO:0071396 145 0.172
muscle tissue development GO:0060537 308 0.163
macromolecular complex disassembly GO:0032984 43 0.160
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.158
Mouse
cellular protein complex disassembly GO:0043624 36 0.154
Mouse
regulation of organelle organization GO:0033043 289 0.138
Mouse
cellular response to corticosteroid stimulus GO:0071384 13 0.136
negative regulation of organelle organization GO:0010639 90 0.136
Mouse
amine metabolic process GO:0009308 45 0.134
cellular amino acid metabolic process GO:0006520 103 0.132
negative regulation of cytoskeleton organization GO:0051494 36 0.130
Mouse
microtubule based process GO:0007017 236 0.117
Mouse
response to organic cyclic compound GO:0014070 198 0.115
regulation of muscle system process GO:0090257 80 0.101
microtubule cytoskeleton organization GO:0000226 157 0.100
Mouse
cellular response to hormone stimulus GO:0032870 150 0.100
cation transport GO:0006812 399 0.098
cellular amine metabolic process GO:0044106 44 0.095
myosin filament assembly GO:0031034 2 0.093
negative regulation of cellular component organization GO:0051129 194 0.092
Mouse
regulation of microtubule cytoskeleton organization GO:0070507 37 0.084
Mouse
myosin filament organization GO:0031033 3 0.079
transmembrane transport GO:0055085 412 0.076
regulation of cellular amine metabolic process GO:0033238 20 0.076
ion transmembrane transport GO:0034220 361 0.075
cation transmembrane transport GO:0098655 266 0.074
oxidation reduction process GO:0055114 342 0.073
regulation of membrane potential GO:0042391 192 0.073
muscle cell differentiation GO:0042692 261 0.069
striated muscle myosin thick filament assembly GO:0071688 1 0.068
muscle cell development GO:0055001 133 0.065
inorganic ion transmembrane transport GO:0098660 234 0.064
purine nucleotide metabolic process GO:0006163 302 0.061
striated muscle contraction GO:0006941 45 0.060
cellular ketone metabolic process GO:0042180 84 0.056
cardiac muscle tissue development GO:0048738 130 0.054
potassium ion transport GO:0006813 52 0.051
ribonucleoside metabolic process GO:0009119 245 0.051
aromatic compound catabolic process GO:0019439 286 0.050
response to alcohol GO:0097305 48 0.049
cellular component assembly involved in morphogenesis GO:0010927 139 0.047
purine nucleoside triphosphate metabolic process GO:0009144 226 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
organelle assembly GO:0070925 177 0.046
heterocycle catabolic process GO:0046700 280 0.046
response to corticosteroid GO:0031960 20 0.045
striated muscle tissue development GO:0014706 293 0.045
cellular response to alcohol GO:0097306 23 0.043
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
developmental growth involved in morphogenesis GO:0060560 138 0.043
regionalization GO:0003002 337 0.042
skeletal myofibril assembly GO:0014866 4 0.042
nucleoside phosphate catabolic process GO:1901292 222 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
skeletal muscle organ development GO:0060538 163 0.041
regulation of ion transport GO:0043269 215 0.041
nucleoside triphosphate metabolic process GO:0009141 230 0.041
actin filament based movement GO:0030048 23 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
monocarboxylic acid metabolic process GO:0032787 191 0.039
organic hydroxy compound metabolic process GO:1901615 203 0.039
inorganic cation transmembrane transport GO:0098662 207 0.039
nucleoside metabolic process GO:0009116 246 0.039
carbohydrate metabolic process GO:0005975 230 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
purine ribonucleotide metabolic process GO:0009150 290 0.038
ras protein signal transduction GO:0007265 77 0.037
blood circulation GO:0008015 195 0.037
homeostasis of number of cells GO:0048872 210 0.036
apoptotic signaling pathway GO:0097190 306 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
purine containing compound catabolic process GO:0072523 213 0.036
heart contraction GO:0060047 93 0.036
cellular chemical homeostasis GO:0055082 215 0.035
metal ion homeostasis GO:0055065 189 0.035
cellular lipid metabolic process GO:0044255 323 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
muscle fiber development GO:0048747 76 0.034
myotube cell development GO:0014904 60 0.034
positive regulation of programmed cell death GO:0043068 218 0.034
regulation of system process GO:0044057 200 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.033
cellular homeostasis GO:0019725 240 0.033
regulation of actin filament based process GO:0032970 99 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
urogenital system development GO:0001655 261 0.033
ribonucleoside catabolic process GO:0042454 206 0.032
actin mediated cell contraction GO:0070252 15 0.032
glycosyl compound metabolic process GO:1901657 246 0.032
peptidyl amino acid modification GO:0018193 336 0.032
purine nucleoside catabolic process GO:0006152 205 0.031
locomotory behavior GO:0007626 195 0.031
multicellular organismal signaling GO:0035637 91 0.031
regulation of cell cycle GO:0051726 281 0.031
regulation of nucleotide metabolic process GO:0006140 169 0.031
organophosphate catabolic process GO:0046434 232 0.030
regulation of cell activation GO:0050865 289 0.030
nucleotide metabolic process GO:0009117 332 0.030
regulation of nucleotide catabolic process GO:0030811 122 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
skeletal muscle fiber development GO:0048741 58 0.030
regulation of homeostatic process GO:0032844 182 0.030
cell adhesion GO:0007155 329 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
nucleoside catabolic process GO:0009164 206 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.029
purine containing compound metabolic process GO:0072521 311 0.029
anion transport GO:0006820 177 0.029
central nervous system neuron differentiation GO:0021953 162 0.029
renal system development GO:0072001 225 0.028
atp metabolic process GO:0046034 75 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
rhythmic process GO:0048511 174 0.028
skeletal system development GO:0001501 356 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
cardiac muscle contraction GO:0060048 32 0.027
sensory organ morphogenesis GO:0090596 242 0.027
nucleoside monophosphate metabolic process GO:0009123 85 0.026
regulation of hydrolase activity GO:0051336 246 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
sequestering of calcium ion GO:0051208 18 0.026
negative regulation of molecular function GO:0044092 258 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
regulation of cell cycle process GO:0010564 160 0.026
sequestering of metal ion GO:0051238 19 0.026
actin filament organization GO:0007015 113 0.025
positive regulation of cell development GO:0010720 237 0.025
developmental maturation GO:0021700 193 0.025
connective tissue development GO:0061448 179 0.025
nuclear division GO:0000280 158 0.025
synaptic transmission GO:0007268 329 0.024
organelle fission GO:0048285 170 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
hexose metabolic process GO:0019318 98 0.024
adult behavior GO:0030534 135 0.024
ribonucleoside monophosphate metabolic process GO:0009161 80 0.024
regulation of muscle contraction GO:0006937 49 0.024
negative regulation of protein metabolic process GO:0051248 282 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
myotube differentiation GO:0014902 105 0.023
response to organonitrogen compound GO:0010243 246 0.023
spermatogenesis GO:0007283 284 0.023
monosaccharide metabolic process GO:0005996 106 0.023
positive regulation of cell death GO:0010942 224 0.023
regulation of skeletal muscle adaptation GO:0014733 12 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
organic acid biosynthetic process GO:0016053 86 0.023
forebrain development GO:0030900 302 0.023
skeletal muscle adaptation GO:0043501 16 0.022
Rat
organonitrogen compound catabolic process GO:1901565 264 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
purine nucleoside monophosphate metabolic process GO:0009126 81 0.022
organic hydroxy compound transport GO:0015850 93 0.022
rho protein signal transduction GO:0007266 32 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
positive regulation of protein modification process GO:0031401 299 0.022
cellular protein complex assembly GO:0043623 116 0.022
gland development GO:0048732 330 0.022
sensory perception GO:0007600 245 0.022
muscle filament sliding GO:0030049 1 0.022
cardiac muscle cell contraction GO:0086003 7 0.022
regulation of neuron differentiation GO:0045664 281 0.022
mesoderm development GO:0007498 100 0.021
actomyosin structure organization GO:0031032 56 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
negative regulation of immune system process GO:0002683 209 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
mitotic cell cycle process GO:1903047 159 0.021
embryonic epithelial tube formation GO:0001838 130 0.021
transmission of nerve impulse GO:0019226 76 0.021
kidney development GO:0001822 213 0.021
regulation of cell projection organization GO:0031344 206 0.020
action potential GO:0001508 78 0.020
maintenance of location GO:0051235 89 0.020
small molecule biosynthetic process GO:0044283 132 0.020
glucose metabolic process GO:0006006 92 0.020
circulatory system process GO:0003013 197 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
segmentation GO:0035282 93 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
ribonucleoside monophosphate catabolic process GO:0009158 57 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
Mouse
digestive system development GO:0055123 200 0.019
response to inorganic substance GO:0010035 96 0.019
striated muscle cell development GO:0055002 125 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
axonogenesis GO:0007409 274 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
response to oxidative stress GO:0006979 123 0.019
cardiac chamber development GO:0003205 108 0.019
regulation of hormone levels GO:0010817 211 0.019
nitrogen compound transport GO:0071705 271 0.019
regulation of cytokine production GO:0001817 266 0.019
heart morphogenesis GO:0003007 178 0.018
nucleotide catabolic process GO:0009166 217 0.018
cellular ion homeostasis GO:0006873 165 0.018
positive regulation of nervous system development GO:0051962 221 0.018
cytoplasmic transport GO:0016482 234 0.018
regulation of metal ion transport GO:0010959 106 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
mitotic cell cycle GO:0000278 195 0.018
regulation of myotube differentiation GO:0010830 62 0.018
heart process GO:0003015 94 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
endocytosis GO:0006897 168 0.017
lipid biosynthetic process GO:0008610 179 0.017
neuron death GO:0070997 154 0.017
ventricular cardiac muscle cell action potential GO:0086005 4 0.017
organic anion transport GO:0015711 137 0.017
neural tube formation GO:0001841 108 0.017
skeletal muscle thin filament assembly GO:0030240 2 0.017
response to radiation GO:0009314 165 0.017
regulation of transmembrane transport GO:0034762 128 0.017
cation homeostasis GO:0055080 212 0.017
metanephros development GO:0001656 79 0.017
camera type eye development GO:0043010 266 0.017
male gamete generation GO:0048232 285 0.017
cell type specific apoptotic process GO:0097285 268 0.017
regulation of circadian sleep wake cycle GO:0042749 3 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
neuronal action potential GO:0019228 54 0.017
potassium ion transmembrane transport GO:0071805 43 0.017
regulation of cellular component size GO:0032535 121 0.016
cytokine production GO:0001816 319 0.016
rna interference GO:0016246 2 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
tube formation GO:0035148 140 0.016
cell maturation GO:0048469 127 0.016
gonad development GO:0008406 141 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
fertilization GO:0009566 127 0.016
carboxylic acid transport GO:0046942 100 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
tissue homeostasis GO:0001894 115 0.016
bmp signaling pathway GO:0030509 93 0.016
neurotransmitter transport GO:0006836 76 0.016
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.016
oocyte axis specification GO:0007309 2 0.016
cell growth GO:0016049 130 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.015
chemotaxis GO:0006935 247 0.015
atp catabolic process GO:0006200 55 0.015
regulation of skeletal muscle fiber development GO:0048742 36 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
calcium ion transport GO:0006816 159 0.015
myeloid cell differentiation GO:0030099 233 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
mitochondrion organization GO:0007005 134 0.015
bone development GO:0060348 120 0.015
t cell activation GO:0042110 289 0.015
cellular potassium ion transport GO:0071804 43 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
sulfur compound metabolic process GO:0006790 100 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
regulation of transferase activity GO:0051338 263 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
regulation of protein catabolic process GO:0042176 108 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
regulation of multi organism process GO:0043900 111 0.014
Mouse
multicellular organism growth GO:0035264 161 0.014
neuron apoptotic process GO:0051402 142 0.014
oocyte construction GO:0007308 2 0.014
innate immune response GO:0045087 157 0.014
Mouse
ossification GO:0001503 216 0.014
response to extracellular stimulus GO:0009991 127 0.014
actin myosin filament sliding GO:0033275 1 0.014
organelle localization GO:0051640 179 0.014
mesoderm morphogenesis GO:0048332 64 0.014
regulation of action potential GO:0098900 4 0.014
digestive tract morphogenesis GO:0048546 147 0.014
regulation of neuron projection development GO:0010975 169 0.014
cellular response to oxidative stress GO:0034599 76 0.014
tissue remodeling GO:0048771 102 0.014
protein maturation GO:0051604 176 0.014
muscle tissue morphogenesis GO:0060415 53 0.014
adult locomotory behavior GO:0008344 91 0.014
defense response to bacterium GO:0042742 119 0.014
angiogenesis GO:0001525 201 0.014
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
protein localization to organelle GO:0033365 185 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
stem cell differentiation GO:0048863 268 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of protein maturation GO:1903317 96 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
regulation of intracellular transport GO:0032386 159 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
lateral inhibition GO:0046331 1 0.013
organ growth GO:0035265 117 0.013
telencephalon development GO:0021537 186 0.013
small molecule catabolic process GO:0044282 71 0.013
inflammatory response GO:0006954 244 0.013
negative regulation of protein processing GO:0010955 79 0.013
dna metabolic process GO:0006259 303 0.013
regulation of muscle tissue development GO:1901861 97 0.013
response to light stimulus GO:0009416 135 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of cell adhesion GO:0030155 154 0.013
amino acid transport GO:0006865 61 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
regulation of defense response GO:0031347 233 0.013
multi multicellular organism process GO:0044706 109 0.013
chromatin organization GO:0006325 206 0.013
bundle of his development GO:0003166 4 0.013
amino acid transmembrane transport GO:0003333 37 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
skeletal muscle cell differentiation GO:0035914 66 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
meiotic nuclear division GO:0007126 115 0.012
anion transmembrane transport GO:0098656 71 0.012
membrane depolarization GO:0051899 64 0.012
somite development GO:0061053 81 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of heart contraction GO:0008016 77 0.012
lung development GO:0030324 164 0.012
wnt signaling pathway GO:0016055 188 0.012
multi organism behavior GO:0051705 62 0.012
skeletal muscle myosin thick filament assembly GO:0030241 1 0.012
norepinephrine secretion GO:0048243 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
chromatin modification GO:0016568 187 0.012
meiotic cell cycle GO:0051321 122 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
germ cell development GO:0007281 185 0.012
regulation of protein processing GO:0070613 96 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
respiratory system development GO:0060541 190 0.012
male gonad development GO:0008584 88 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
negative regulation of protein maturation GO:1903318 79 0.012
regulation of cell growth GO:0001558 91 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
tube closure GO:0060606 91 0.012
extracellular structure organization GO:0043062 148 0.012
cofactor metabolic process GO:0051186 80 0.012
regulation of blood circulation GO:1903522 93 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
response to nutrient levels GO:0031667 109 0.012
cognition GO:0050890 149 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
regulation of cellular response to stress GO:0080135 159 0.012
skeletal system morphogenesis GO:0048705 203 0.012
divalent metal ion transport GO:0070838 172 0.012
divalent inorganic cation transport GO:0072511 178 0.012
circadian rhythm GO:0007623 114 0.012
regulation of response to wounding GO:1903034 189 0.012
sulfur compound biosynthetic process GO:0044272 37 0.012
cartilage development GO:0051216 140 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
regulation of vascular wound healing GO:0061043 2 0.012
cardiac ventricle development GO:0003231 83 0.012
regulation of proteolysis GO:0030162 164 0.012
single fertilization GO:0007338 82 0.012
response to oxygen levels GO:0070482 62 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
macromolecule methylation GO:0043414 120 0.012
regulation of feeding behavior GO:0060259 3 0.012
cellular response to external stimulus GO:0071496 88 0.011
negative regulation of kinase activity GO:0033673 81 0.011
myeloid cell homeostasis GO:0002262 114 0.011
regulation of secretion by cell GO:1903530 249 0.011
fatty acid metabolic process GO:0006631 121 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of postsynaptic membrane potential GO:0060078 48 0.011
respiratory tube development GO:0030323 167 0.011
l amino acid transport GO:0015807 32 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.011
response to starvation GO:0042594 65 0.011
pharynx development GO:0060465 1 0.011
epithelial cell proliferation GO:0050673 174 0.011
second messenger mediated signaling GO:0019932 73 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
epithelial tube formation GO:0072175 130 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
dephosphorylation GO:0016311 129 0.011
cardiac muscle tissue morphogenesis GO:0055008 44 0.011
acetate ester transport GO:1901374 2 0.011
response to temperature stimulus GO:0009266 55 0.011
extracellular matrix organization GO:0030198 147 0.011
development of primary sexual characteristics GO:0045137 143 0.011
regulation of myoblast differentiation GO:0045661 29 0.011
digestive tract development GO:0048565 190 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of embryonic development GO:0045995 71 0.011
amide transport GO:0042886 138 0.011
appendage development GO:0048736 166 0.011
acetylcholine transport GO:0015870 2 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
gastrulation GO:0007369 116 0.011
lymphocyte differentiation GO:0030098 242 0.011
myoblast differentiation GO:0045445 52 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
steroid metabolic process GO:0008202 119 0.011
intracellular mrna localization GO:0008298 4 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of nuclear division GO:0051783 56 0.011
mammary placode formation GO:0060596 4 0.011
neuromuscular process GO:0050905 99 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
regulation of secretion GO:0051046 274 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
protein processing GO:0016485 163 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
sarcomere organization GO:0045214 24 0.011
carbohydrate catabolic process GO:0016052 32 0.011
regulation of blood pressure GO:0008217 93 0.010
cellular response to acid chemical GO:0071229 68 0.010
regulation of cell motility GO:2000145 236 0.010
developmental cell growth GO:0048588 84 0.010
regulation of bmp signaling pathway GO:0030510 60 0.010
organic acid transport GO:0015849 101 0.010
response to acid chemical GO:0001101 111 0.010
blood vessel morphogenesis GO:0048514 285 0.010
regulation of ion transmembrane transporter activity GO:0032412 54 0.010
mesenchyme development GO:0060485 152 0.010
kidney epithelium development GO:0072073 121 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.010
stem cell development GO:0048864 219 0.010
regulation of heart rate GO:0002027 36 0.010
cardiac muscle cell development GO:0055013 39 0.010

Trim63 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.050
disease of anatomical entity DOID:7 0 0.050
musculoskeletal system disease DOID:17 0 0.050
muscle tissue disease DOID:66 0 0.050
nervous system disease DOID:863 0 0.029
myopathy DOID:423 0 0.027
heart disease DOID:114 0 0.027
cardiomyopathy DOID:0050700 0 0.027
cardiovascular system disease DOID:1287 0 0.027
intrinsic cardiomyopathy DOID:0060036 0 0.023
hypertrophic cardiomyopathy DOID:11984 0 0.020
disease of metabolism DOID:0014667 0 0.017
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
inherited metabolic disorder DOID:655 0 0.012