Mus musculus

132 known processes

Trim67

tripartite motif-containing 67

(Aliases: TNL,D130049O21Rik)

Trim67 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.157
regulation of cellular amine metabolic process GO:0033238 20 0.112
axonogenesis GO:0007409 274 0.111
Fly
cellular ketone metabolic process GO:0042180 84 0.110
cellular amine metabolic process GO:0044106 44 0.089
cellular amino acid metabolic process GO:0006520 103 0.088
peptidyl amino acid modification GO:0018193 336 0.076
regulation of cellular amino acid metabolic process GO:0006521 5 0.073
amine metabolic process GO:0009308 45 0.070
synaptic transmission GO:0007268 329 0.065
cellular lipid metabolic process GO:0044255 323 0.063
cell adhesion GO:0007155 329 0.062
negative regulation of cellular protein metabolic process GO:0032269 247 0.061
negative regulation of protein metabolic process GO:0051248 282 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
regulation of membrane potential GO:0042391 192 0.047
neuromuscular process GO:0050905 99 0.045
negative regulation of intracellular signal transduction GO:1902532 167 0.045
membrane organization GO:0061024 245 0.043
glial cell differentiation GO:0010001 131 0.042
macromolecule catabolic process GO:0009057 281 0.042
negative regulation of phosphorylation GO:0042326 166 0.042
negative regulation of molecular function GO:0044092 258 0.042
locomotory behavior GO:0007626 195 0.041
cation transport GO:0006812 399 0.041
negative regulation of protein modification process GO:0031400 163 0.041
regulation of neuron differentiation GO:0045664 281 0.039
ribonucleotide metabolic process GO:0009259 291 0.039
transmembrane transport GO:0055085 412 0.038
positive regulation of cell development GO:0010720 237 0.037
fat cell differentiation GO:0045444 160 0.037
sensory system development GO:0048880 3 0.037
cation transmembrane transport GO:0098655 266 0.036
ear development GO:0043583 200 0.036
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
inorganic ion transmembrane transport GO:0098660 234 0.035
extracellular matrix organization GO:0030198 147 0.035
dendrite development GO:0016358 115 0.035
negative regulation of protein phosphorylation GO:0001933 126 0.032
adult behavior GO:0030534 135 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
embryonic organ morphogenesis GO:0048562 276 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.031
developmental maturation GO:0021700 193 0.030
positive regulation of protein modification process GO:0031401 299 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.030
forebrain development GO:0030900 302 0.030
male gamete generation GO:0048232 285 0.030
regulation of organelle organization GO:0033043 289 0.030
gliogenesis GO:0042063 141 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
regulation of protein localization GO:0032880 231 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
lateral line system development GO:0048925 1 0.028
spermatogenesis GO:0007283 284 0.028
regulation of system process GO:0044057 200 0.028
ion transmembrane transport GO:0034220 361 0.028
cell type specific apoptotic process GO:0097285 268 0.027
gland development GO:0048732 330 0.027
synapse organization GO:0050808 125 0.027
single organism cell adhesion GO:0098602 156 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.027
neuron apoptotic process GO:0051402 142 0.026
extracellular structure organization GO:0043062 148 0.026
muscle tissue development GO:0060537 308 0.026
nuclear transport GO:0051169 139 0.026
camera type eye development GO:0043010 266 0.025
dephosphorylation GO:0016311 129 0.025
cartilage development GO:0051216 140 0.025
digestive system development GO:0055123 200 0.025
compound eye development GO:0048749 1 0.025
organelle fission GO:0048285 170 0.025
oxidation reduction process GO:0055114 342 0.025
sensory perception GO:0007600 245 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
axon guidance GO:0007411 141 0.025
Fly
cell division GO:0051301 120 0.025
regulation of neuron death GO:1901214 134 0.024
establishment of organelle localization GO:0051656 122 0.024
ras protein signal transduction GO:0007265 77 0.024
regulation of protein kinase activity GO:0045859 232 0.024
mapk cascade GO:0000165 281 0.024
multicellular organism growth GO:0035264 161 0.024
regulation of cell cycle GO:0051726 281 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
exocytosis GO:0006887 121 0.023
Mouse
single organismal cell cell adhesion GO:0016337 131 0.023
glucose metabolic process GO:0006006 92 0.023
skin development GO:0043588 220 0.023
intracellular protein transport GO:0006886 204 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
regulation of establishment of protein localization GO:0070201 181 0.022
sensory organ morphogenesis GO:0090596 242 0.022
regulation of transferase activity GO:0051338 263 0.022
myeloid cell differentiation GO:0030099 233 0.022
chemotaxis GO:0006935 247 0.021
Fly
telencephalon development GO:0021537 186 0.021
regulation of cell projection organization GO:0031344 206 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
positive regulation of cell death GO:0010942 224 0.021
regulation of secretion GO:0051046 274 0.021
purine containing compound metabolic process GO:0072521 311 0.021
peptidyl tyrosine phosphorylation GO:0018108 143 0.021
peptide hormone secretion GO:0030072 109 0.021
intracellular mrna localization GO:0008298 4 0.021
skeletal system development GO:0001501 356 0.021
cytoplasmic transport GO:0016482 234 0.020
molting cycle GO:0042303 90 0.020
protein ubiquitination GO:0016567 171 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
carbohydrate homeostasis GO:0033500 128 0.020
regulation of defense response GO:0031347 233 0.020
heterocycle catabolic process GO:0046700 280 0.020
negative regulation of nervous system development GO:0051961 156 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
positive regulation of secretion by cell GO:1903532 114 0.020
calcium ion dependent exocytosis GO:0017156 35 0.020
Mouse
pole plasm assembly GO:0007315 2 0.020
epithelial cell development GO:0002064 159 0.019
mitotic cell cycle GO:0000278 195 0.019
nucleotide metabolic process GO:0009117 332 0.019
peptide transport GO:0015833 133 0.019
cell growth GO:0016049 130 0.019
chromatin organization GO:0006325 206 0.019
action potential GO:0001508 78 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
retina morphogenesis in camera type eye GO:0060042 45 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
endocytosis GO:0006897 168 0.019
visual perception GO:0007601 52 0.019
stem cell development GO:0048864 219 0.019
regulation of ion transport GO:0043269 215 0.019
innate immune response GO:0045087 157 0.019
regulation of neuron projection development GO:0010975 169 0.019
positive regulation of nervous system development GO:0051962 221 0.019
glucose homeostasis GO:0042593 128 0.019
retina development in camera type eye GO:0060041 119 0.018
renal system development GO:0072001 225 0.018
ectoderm formation GO:0001705 3 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
hindbrain development GO:0030902 128 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
digestive tract morphogenesis GO:0048546 147 0.018
oocyte axis specification GO:0007309 2 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
protein catabolic process GO:0030163 221 0.018
gastrulation GO:0007369 116 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
protein localization to organelle GO:0033365 185 0.018
regulation of hydrolase activity GO:0051336 246 0.018
carbohydrate metabolic process GO:0005975 230 0.018
connective tissue development GO:0061448 179 0.018
germ cell development GO:0007281 185 0.017
nitrogen compound transport GO:0071705 271 0.017
water homeostasis GO:0030104 27 0.017
peripheral nervous system neuron axonogenesis GO:0048936 3 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
oocyte construction GO:0007308 2 0.017
sensory perception of mechanical stimulus GO:0050954 107 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
microtubule based process GO:0007017 236 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
rho protein signal transduction GO:0007266 32 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
cognition GO:0050890 149 0.017
blood circulation GO:0008015 195 0.017
nuclear division GO:0000280 158 0.017
response to organonitrogen compound GO:0010243 246 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
circulatory system process GO:0003013 197 0.017
regulation of anatomical structure size GO:0090066 178 0.016
detection of stimulus GO:0051606 84 0.016
cell maturation GO:0048469 127 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
regulation of binding GO:0051098 111 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
apoptotic signaling pathway GO:0097190 306 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
neuron projection extension GO:1990138 64 0.016
stem cell differentiation GO:0048863 268 0.016
bone development GO:0060348 120 0.016
negative regulation of cell cycle GO:0045786 123 0.016
nucleotide catabolic process GO:0009166 217 0.016
positive regulation of transferase activity GO:0051347 167 0.016
multicellular organismal signaling GO:0035637 91 0.016
sensory perception of sound GO:0007605 97 0.016
regulation of secretion by cell GO:1903530 249 0.016
endomembrane system organization GO:0010256 147 0.015
positive regulation of cell motility GO:2000147 116 0.015
protein maturation GO:0051604 176 0.015
organelle localization GO:0051640 179 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.015
cellular homeostasis GO:0019725 240 0.015
regulation of cell motility GO:2000145 236 0.015
learning GO:0007612 98 0.015
regulation of response to wounding GO:1903034 189 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
wound healing GO:0042060 157 0.015
regulation of peptide secretion GO:0002791 77 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
response to light stimulus GO:0009416 135 0.015
developmental cell growth GO:0048588 84 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
protein targeting GO:0006605 143 0.014
mitotic nuclear division GO:0007067 48 0.014
astrocyte differentiation GO:0048708 43 0.014
regulation of cell cycle process GO:0010564 160 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
respiratory system development GO:0060541 190 0.014
cerebral cortex development GO:0021987 86 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
cytokine production GO:0001816 319 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
maintenance of location GO:0051235 89 0.014
mitotic cell cycle process GO:1903047 159 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
neuron projection guidance GO:0097485 141 0.014
Fly
establishment of protein localization to organelle GO:0072594 118 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
negative regulation of kinase activity GO:0033673 81 0.014
nucleoside metabolic process GO:0009116 246 0.014
aromatic compound catabolic process GO:0019439 286 0.014
methylation GO:0032259 134 0.014
purine containing compound catabolic process GO:0072523 213 0.014
fatty acid metabolic process GO:0006631 121 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
regulation of multi organism process GO:0043900 111 0.014
neuronal action potential GO:0019228 54 0.013
regulation of proteolysis GO:0030162 164 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
neurotransmitter transport GO:0006836 76 0.013
cellular response to lipid GO:0071396 145 0.013
wnt signaling pathway GO:0016055 188 0.013
anatomical structure homeostasis GO:0060249 145 0.013
lens development in camera type eye GO:0002088 62 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
protein localization to membrane GO:0072657 108 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
cardiac endothelial cell differentiation GO:0003348 4 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
defecation GO:0030421 1 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
forebrain cell migration GO:0021885 58 0.013
heart process GO:0003015 94 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
positive regulation of fatty acid oxidation GO:0046321 4 0.013
skeletal system morphogenesis GO:0048705 203 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
regulation of protein transport GO:0051223 163 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
organ growth GO:0035265 117 0.013
regulation of carbohydrate metabolic process GO:0006109 75 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of kinase activity GO:0043549 249 0.013
heart morphogenesis GO:0003007 178 0.013
organelle assembly GO:0070925 177 0.013
neuromuscular process controlling balance GO:0050885 59 0.013
mitochondrion organization GO:0007005 134 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
positive regulation of secretion GO:0051047 130 0.013
homeostasis of number of cells GO:0048872 210 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
neuron death GO:0070997 154 0.013
chromatin modification GO:0016568 187 0.013
regulation of intracellular transport GO:0032386 159 0.013
appendage development GO:0048736 166 0.013
cerebral cortex cell migration GO:0021795 44 0.013
peptidyl serine modification GO:0018209 83 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
mrna metabolic process GO:0016071 84 0.012
protein processing GO:0016485 163 0.012
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis GO:0060598 2 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
ossification GO:0001503 216 0.012
proprioception GO:0019230 4 0.012
organic anion transport GO:0015711 137 0.012
regulation of feeding behavior GO:0060259 3 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
amide transport GO:0042886 138 0.012
regulation of postsynaptic membrane potential GO:0060078 48 0.012
epidermis development GO:0008544 187 0.012
dna metabolic process GO:0006259 303 0.012
lipid modification GO:0030258 65 0.012
hormone secretion GO:0046879 128 0.012
monosaccharide transport GO:0015749 58 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
metanephric dct cell differentiation GO:0072240 3 0.012
cation homeostasis GO:0055080 212 0.012
transdifferentiation GO:0060290 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
embryonic skeletal system morphogenesis GO:0048704 91 0.012
negative regulation of transferase activity GO:0051348 85 0.012
sa node cell action potential GO:0086015 4 0.012
macromolecule methylation GO:0043414 120 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.011
spinal cord motor neuron migration GO:0097476 4 0.011
neuroblast differentiation GO:0014016 2 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
protein import GO:0017038 101 0.011
neuron migration GO:0001764 122 0.011
regulation of cell migration GO:0030334 219 0.011
insulin secretion GO:0030073 89 0.011
hexose metabolic process GO:0019318 98 0.011
lateral inhibition GO:0046331 1 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
blastocyst development GO:0001824 80 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
sulfur compound biosynthetic process GO:0044272 37 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
smoothened signaling pathway GO:0007224 105 0.011
response to lipopolysaccharide GO:0032496 128 0.011
glucose transport GO:0015758 56 0.011
nuclear import GO:0051170 95 0.011
kidney development GO:0001822 213 0.011
vesicle organization GO:0016050 60 0.011
regulation of cell activation GO:0050865 289 0.011
monosaccharide metabolic process GO:0005996 106 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
conditioned taste aversion GO:0001661 4 0.011
somatotropin secreting cell development GO:0060133 2 0.011
mrna processing GO:0006397 63 0.011
rna processing GO:0006396 105 0.011
regulation of inflammatory response GO:0050727 147 0.011
heart contraction GO:0060047 93 0.011
single organism nuclear import GO:1902593 95 0.011
regulation of synaptic plasticity GO:0048167 87 0.011
multi organism behavior GO:0051705 62 0.011
detection of abiotic stimulus GO:0009582 60 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
protein localization to nucleus GO:0034504 121 0.011
ear morphogenesis GO:0042471 118 0.011
adult locomotory behavior GO:0008344 91 0.011
stem cell maintenance GO:0019827 130 0.011
fertilization GO:0009566 127 0.010
Mouse
positive regulation of kinase activity GO:0033674 155 0.010
positive regulation of necrotic cell death GO:0010940 1 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
mesenchymal cell development GO:0014031 93 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
regionalization GO:0003002 337 0.010
regulation of cytokine production GO:0001817 266 0.010
organophosphate catabolic process GO:0046434 232 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
metanephric loop of henle development GO:0072236 4 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010
cell junction organization GO:0034330 77 0.010
glycerolipid metabolic process GO:0046486 122 0.010
regulation of heart contraction GO:0008016 77 0.010
striated muscle tissue development GO:0014706 293 0.010
blood vessel morphogenesis GO:0048514 285 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
glycoprotein metabolic process GO:0009100 116 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
mitotic cytokinesis GO:0000281 4 0.010
muscle cell differentiation GO:0042692 261 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
tube formation GO:0035148 140 0.010
anion transport GO:0006820 177 0.010

Trim67 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
sensory system disease DOID:0050155 0 0.025
eye and adnexa disease DOID:1492 0 0.024
eye disease DOID:5614 0 0.018
central nervous system disease DOID:331 0 0.012