Mus musculus

0 known processes

Abca8a

ATP-binding cassette, sub-family A (ABC1), member 8a

Abca8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
naphthalene containing compound metabolic process GO:0090420 1 0.117
drug metabolic process GO:0017144 4 0.080
nucleobase containing small molecule metabolic process GO:0055086 352 0.077
cellular alcohol metabolic process GO:0044107 3 0.075
fatty acid metabolic process GO:0006631 121 0.070
blood circulation GO:0008015 195 0.067
ion transmembrane transport GO:0034220 361 0.067
cellular lipid metabolic process GO:0044255 323 0.065
drug catabolic process GO:0042737 2 0.060
calcitriol biosynthetic process from calciol GO:0036378 3 0.058
oxidation reduction process GO:0055114 342 0.057
cellular alcohol biosynthetic process GO:0044108 3 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.052
muscle system process GO:0003012 141 0.051
cell adhesion GO:0007155 329 0.051
secondary alcohol metabolic process GO:1902652 3 0.051
nucleotide metabolic process GO:0009117 332 0.051
naphthalene metabolic process GO:0018931 1 0.050
defense response to other organism GO:0098542 197 0.048
inorganic cation transmembrane transport GO:0098662 207 0.046
fat soluble vitamin biosynthetic process GO:0042362 4 0.045
regulation of secretion by cell GO:1903530 249 0.044
inorganic ion transmembrane transport GO:0098660 234 0.044
cofactor metabolic process GO:0051186 80 0.042
camera type eye development GO:0043010 266 0.042
negative regulation of cell proliferation GO:0008285 296 0.042
regulation of secretion GO:0051046 274 0.041
positive regulation of nervous system development GO:0051962 221 0.041
cellular response to cadmium ion GO:0071276 3 0.041
regulation of system process GO:0044057 200 0.041
regulation of ion transmembrane transport GO:0034765 119 0.039
transmembrane transport GO:0055085 412 0.039
response to organic cyclic compound GO:0014070 198 0.037
regulation of neuron differentiation GO:0045664 281 0.036
cation transport GO:0006812 399 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
cellular amine metabolic process GO:0044106 44 0.035
amine metabolic process GO:0009308 45 0.035
extracellular structure organization GO:0043062 148 0.035
regulation of cytokine production GO:0001817 266 0.035
reactive oxygen species metabolic process GO:0072593 84 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
regulation of defense response GO:0031347 233 0.034
regulation of blood pressure GO:0008217 93 0.034
cation transmembrane transport GO:0098655 266 0.034
regulation of membrane potential GO:0042391 192 0.033
ribonucleotide metabolic process GO:0009259 291 0.032
regulation of cell projection organization GO:0031344 206 0.031
regulation of ion transport GO:0043269 215 0.030
nadp metabolic process GO:0006739 6 0.030
regulation of homeostatic process GO:0032844 182 0.030
vitamin d3 metabolic process GO:0070640 3 0.030
cellular ketone metabolic process GO:0042180 84 0.029
response to organonitrogen compound GO:0010243 246 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
regulation of muscle system process GO:0090257 80 0.028
cytokine production GO:0001816 319 0.028
sodium ion transmembrane transport GO:0035725 49 0.028
cation homeostasis GO:0055080 212 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
ras protein signal transduction GO:0007265 77 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
calcium ion transport GO:0006816 159 0.026
renal tubular secretion GO:0097254 2 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.025
peptidyl amino acid modification GO:0018193 336 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
circulatory system process GO:0003013 197 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
regulation of cell adhesion GO:0030155 154 0.025
extracellular matrix organization GO:0030198 147 0.024
cell substrate adhesion GO:0031589 130 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
renal system development GO:0072001 225 0.023
response to acid chemical GO:0001101 111 0.023
regulation of kinase activity GO:0043549 249 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.022
multicellular organismal signaling GO:0035637 91 0.022
cellular homeostasis GO:0019725 240 0.022
gland development GO:0048732 330 0.022
axonogenesis GO:0007409 274 0.022
regulation of hydrolase activity GO:0051336 246 0.022
rhodopsin mediated signaling pathway GO:0016056 4 0.022
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.022
regulation of chloride transport GO:2001225 2 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
sodium ion export GO:0071436 2 0.022
cytoplasmic transport GO:0016482 234 0.022
response to molecule of bacterial origin GO:0002237 143 0.021
innate immune response GO:0045087 157 0.021
regulation of neuron projection development GO:0010975 169 0.021
cellular response to lipid GO:0071396 145 0.021
muscle contraction GO:0006936 101 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
regulation of systemic arterial blood pressure GO:0003073 61 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
regulation of feeding behavior GO:0060259 3 0.020
regulation of protein localization GO:0032880 231 0.020
compound eye development GO:0048749 1 0.020
pigment metabolic process GO:0042440 32 0.020
synaptic transmission GO:0007268 329 0.019
positive regulation of protein modification process GO:0031401 299 0.019
heterocycle catabolic process GO:0046700 280 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
membrane organization GO:0061024 245 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
forebrain development GO:0030900 302 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
vitamin d biosynthetic process GO:0042368 3 0.018
regulation of organelle organization GO:0033043 289 0.018
lipid biosynthetic process GO:0008610 179 0.018
mapk cascade GO:0000165 281 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
inflammatory response GO:0006954 244 0.018
cellular ion homeostasis GO:0006873 165 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
aromatic compound catabolic process GO:0019439 286 0.018
organophosphate catabolic process GO:0046434 232 0.018
regulation of transmembrane transport GO:0034762 128 0.018
carbohydrate metabolic process GO:0005975 230 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
regulation of ion homeostasis GO:2000021 64 0.017
divalent metal ion transport GO:0070838 172 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
immune effector process GO:0002252 321 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
regulation of mapk cascade GO:0043408 248 0.017
regulation of neurotransmitter levels GO:0001505 87 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
regulation of anatomical structure size GO:0090066 178 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
sensory perception GO:0007600 245 0.016
regulation of cell cycle GO:0051726 281 0.016
dna metabolic process GO:0006259 303 0.016
small molecule biosynthetic process GO:0044283 132 0.016
sequestering of calcium ion GO:0051208 18 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
sequestering of metal ion GO:0051238 19 0.016
second messenger mediated signaling GO:0019932 73 0.016
t cell activation GO:0042110 289 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
respiratory system development GO:0060541 190 0.016
maintenance of location GO:0051235 89 0.016
pyridine nucleotide catabolic process GO:0019364 3 0.016
multicellular organism growth GO:0035264 161 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
response to growth factor GO:0070848 198 0.016
muscle cell differentiation GO:0042692 261 0.016
regulation of hormone levels GO:0010817 211 0.016
positive regulation of transferase activity GO:0051347 167 0.015
positive regulation of cell development GO:0010720 237 0.015
organic hydroxy compound biosynthetic process GO:1901617 77 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
negative regulation of molecular function GO:0044092 258 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
cellular chemical homeostasis GO:0055082 215 0.015
spermatogenesis GO:0007283 284 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
nucleoside catabolic process GO:0009164 206 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
rhythmic process GO:0048511 174 0.015
cardiac muscle cell contraction GO:0086003 7 0.015
nucleoside metabolic process GO:0009116 246 0.015
positive regulation of cell substrate adhesion GO:0010811 47 0.015
oxygen metabolic process GO:0072592 4 0.015
response to lipopolysaccharide GO:0032496 128 0.015
protein localization to membrane GO:0072657 108 0.015
hindbrain development GO:0030902 128 0.015
spermatid development GO:0007286 108 0.015
regulation of ion transmembrane transporter activity GO:0032412 54 0.015
multi multicellular organism process GO:0044706 109 0.015
endocytosis GO:0006897 168 0.015
oligopeptide transmembrane transport GO:0035672 4 0.015
negative regulation of protein metabolic process GO:0051248 282 0.014
regulation of tube size GO:0035150 57 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
adult behavior GO:0030534 135 0.014
urogenital system development GO:0001655 261 0.014
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.014
myeloid cell differentiation GO:0030099 233 0.014
cellular amino acid metabolic process GO:0006520 103 0.014
positive regulation of transmembrane transport GO:0034764 29 0.014
defense response to bacterium GO:0042742 119 0.014
organic hydroxy compound transport GO:0015850 93 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
regulation of inflammatory response GO:0050727 147 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
positive regulation of cytokine production GO:0001819 174 0.014
regulation of estrogen secretion GO:2000861 1 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
germ cell development GO:0007281 185 0.014
alcohol metabolic process GO:0006066 116 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
activation of immune response GO:0002253 138 0.014
unsaturated fatty acid metabolic process GO:0033559 31 0.014
neuron projection extension GO:1990138 64 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
organic acid biosynthetic process GO:0016053 86 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
macromolecule catabolic process GO:0009057 281 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
purine containing compound metabolic process GO:0072521 311 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
neuron death GO:0070997 154 0.013
metal ion homeostasis GO:0055065 189 0.013
midgut development GO:0007494 4 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of vasculature development GO:1901342 88 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
positive regulation of ion transport GO:0043270 65 0.013
organelle localization GO:0051640 179 0.013
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.013
regulation of intracellular transport GO:0032386 159 0.013
positive regulation of immune effector process GO:0002699 107 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
nephron development GO:0072006 109 0.013
establishment of organelle localization GO:0051656 122 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
purine containing compound catabolic process GO:0072523 213 0.013
cell type specific apoptotic process GO:0097285 268 0.013
single organism cell adhesion GO:0098602 156 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
lipid transport GO:0006869 98 0.012
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.012
icosanoid metabolic process GO:0006690 33 0.012
sensory organ morphogenesis GO:0090596 242 0.012
epithelial cell proliferation GO:0050673 174 0.012
heart morphogenesis GO:0003007 178 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
vascular process in circulatory system GO:0003018 62 0.012
fatty acid biosynthetic process GO:0006633 41 0.012
regulation of metal ion transport GO:0010959 106 0.012
regulation of calcium ion transport GO:0051924 69 0.012
skeletal system development GO:0001501 356 0.012
cardiac muscle cell differentiation GO:0055007 69 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
respiratory tube development GO:0030323 167 0.012
positive regulation of cellular ph reduction GO:0032849 2 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
endocrine process GO:0050886 39 0.012
oxidoreduction coenzyme metabolic process GO:0006733 16 0.012
neuron projection guidance GO:0097485 141 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
circadian rhythm GO:0007623 114 0.012
regulation of cardiac muscle contraction GO:0055117 21 0.012
blood vessel morphogenesis GO:0048514 285 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
response to inorganic substance GO:0010035 96 0.012
tissue homeostasis GO:0001894 115 0.012
regulation of cellular response to stress GO:0080135 159 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
striated muscle tissue development GO:0014706 293 0.012
protein localization to organelle GO:0033365 185 0.012
spermatid differentiation GO:0048515 115 0.012
axon guidance GO:0007411 141 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
regulation of proteolysis GO:0030162 164 0.012
positive regulation of secretion GO:0051047 130 0.012
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.012
anatomical structure homeostasis GO:0060249 145 0.012
sulfur compound metabolic process GO:0006790 100 0.012
regulation of cell size GO:0008361 72 0.012
protein targeting GO:0006605 143 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.011
negative regulation of wnt signaling pathway GO:0030178 73 0.011
coenzyme metabolic process GO:0006732 52 0.011
steroid metabolic process GO:0008202 119 0.011
regulation of transporter activity GO:0032409 57 0.011
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
metencephalon development GO:0022037 89 0.011
fat cell differentiation GO:0045444 160 0.011
lipid localization GO:0010876 126 0.011
regulation of multi organism process GO:0043900 111 0.011
nucleotide catabolic process GO:0009166 217 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
response to extracellular stimulus GO:0009991 127 0.011
cell matrix adhesion GO:0007160 68 0.011
chemotaxis GO:0006935 247 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
response to radiation GO:0009314 165 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
digestive system development GO:0055123 200 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
rho protein signal transduction GO:0007266 32 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
nicotinamide nucleotide metabolic process GO:0046496 12 0.011
locomotory behavior GO:0007626 195 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
male gamete generation GO:0048232 285 0.011
cell growth GO:0016049 130 0.011
endomembrane system organization GO:0010256 147 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
positive regulation of kinase activity GO:0033674 155 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
fertilization GO:0009566 127 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
sodium ion transport GO:0006814 73 0.011
regulation of transferase activity GO:0051338 263 0.011
renal system process GO:0003014 48 0.011
nitrogen compound transport GO:0071705 271 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.011
regulation of angiogenesis GO:0045765 81 0.011
lateral line system development GO:0048925 1 0.011
protein localization to plasma membrane GO:0072659 57 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
gliogenesis GO:0042063 141 0.011
hormone secretion GO:0046879 128 0.010
negative regulation of phospholipase activity GO:0010519 4 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
regulation of cell activation GO:0050865 289 0.010
chondroitin sulfate metabolic process GO:0030204 17 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
stem cell differentiation GO:0048863 268 0.010
telencephalon development GO:0021537 186 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
response to drug GO:0042493 75 0.010
asymmetric stem cell division GO:0098722 3 0.010
cell activation involved in immune response GO:0002263 126 0.010
muscle tissue development GO:0060537 308 0.010
lymphocyte proliferation GO:0046651 164 0.010
response to oxidative stress GO:0006979 123 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
cellular protein complex assembly GO:0043623 116 0.010
purine nucleotide catabolic process GO:0006195 211 0.010

Abca8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.045
disease of anatomical entity DOID:7 0 0.045
central nervous system disease DOID:331 0 0.025
cardiovascular system disease DOID:1287 0 0.024
musculoskeletal system disease DOID:17 0 0.024
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
eye disease DOID:5614 0 0.023
disease by infectious agent DOID:0050117 0 0.012
viral infectious disease DOID:934 0 0.012
normocytic anemia DOID:720 0 0.012
hemolytic uremic syndrome DOID:12554 0 0.012
anemia DOID:2355 0 0.012
hemolytic anemia DOID:583 0 0.012
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
neurodegenerative disease DOID:1289 0 0.011
muscular disease DOID:0080000 0 0.011
myopathy DOID:423 0 0.011
muscle tissue disease DOID:66 0 0.011
brain disease DOID:936 0 0.010