Mus musculus

302 known processes

Ccr2

chemokine (C-C motif) receptor 2

(Aliases: Ccr2b,Ccr2a,Ckr2,Ckr2b,Ckr2a,Cmkbr2,Cc-ckr-2,mJe-r)

Ccr2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
t cell extravasation GO:0072683 4 1.000
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 1.000
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 1.000
positive regulation of monocyte chemotaxis GO:0090026 2 1.000
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 1.000
eosinophil degranulation GO:0043308 1 1.000
immune complex clearance GO:0002434 2 0.999
microglial cell activation involved in immune response GO:0002282 1 0.999
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.999
eosinophil activation involved in immune response GO:0002278 1 0.999
granulocyte chemotaxis GO:0071621 39 0.999
Mouse
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.999
Mouse
dendritic cell chemotaxis GO:0002407 7 0.998
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.998
immune complex clearance by monocytes and macrophages GO:0002436 2 0.998
cellular extravasation GO:0045123 17 0.998
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.997
Mouse
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.997
leukocyte migration GO:0050900 124 0.997
granulocyte migration GO:0097530 43 0.997
Mouse
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.996
regulation of monocyte extravasation GO:2000437 2 0.996
interleukin 18 mediated signaling pathway GO:0035655 2 0.996
macrophage chemotaxis GO:0048246 14 0.995
Mouse
response to defense related nitric oxide production by other organism involved in symbiotic interaction GO:0052551 2 0.995
chemokine mediated signaling pathway GO:0070098 17 0.995
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.995
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.993
positive regulation of macrophage chemotaxis GO:0010759 5 0.993
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.993
Mouse
positive regulation of immunological synapse formation GO:2000522 1 0.992
Mouse
lymphocyte migration GO:0072676 26 0.991
regulation of dendritic cell chemotaxis GO:2000508 1 0.990
Mouse
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.990
regulation of interleukin 1 beta secretion GO:0050706 15 0.989
Mouse
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.989
interleukin 12 secretion GO:0072610 3 0.989
Mouse
regulation of lymphocyte activation GO:0051249 240 0.988
negative thymic t cell selection GO:0045060 12 0.988
Mouse
cellular response to biotic stimulus GO:0071216 92 0.988
immune effector process GO:0002252 321 0.987
cytosolic calcium ion transport GO:0060401 48 0.987
Mouse
response to defense related host nitric oxide production GO:0052565 2 0.987
cellular response to peptidoglycan GO:0071224 4 0.986
regulation of lymphocyte proliferation GO:0050670 117 0.986
response to molecule of fungal origin GO:0002238 4 0.985
interferon beta biosynthetic process GO:0045350 4 0.985
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.985
Mouse
positive regulation of t cell proliferation GO:0042102 52 0.984
positive regulation of cell migration GO:0030335 109 0.982
negative regulation of macrophage apoptotic process GO:2000110 3 0.981
Mouse
modulation by symbiont of defense related host nitric oxide production GO:0052163 1 0.981
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.981
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.981
Mouse
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.981
regulation of t cell costimulation GO:2000523 2 0.980
Mouse
cellular response to interleukin 18 GO:0071351 3 0.980
regulation of antigen processing and presentation GO:0002577 10 0.978
Mouse
regulation of angiogenesis GO:0045765 81 0.978
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.977
regulation of cell activation GO:0050865 289 0.976
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070428 3 0.976
myeloid leukocyte migration GO:0097529 57 0.975
eosinophil mediated immunity GO:0002447 1 0.975
innate immune response GO:0045087 157 0.974
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.973
regulation of immunological synapse formation GO:2000520 2 0.973
Mouse
positive regulation of monocyte extravasation GO:2000439 1 0.971
response to defenses of other organism involved in symbiotic interaction GO:0052173 3 0.970
positive regulation by symbiont of host immune response GO:0052556 1 0.969
myeloid leukocyte differentiation GO:0002573 119 0.968
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.968
Mouse
positive regulation of neutrophil chemotaxis GO:0090023 12 0.967
Mouse
organ or tissue specific immune response GO:0002251 13 0.967
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.966
eosinophil activation GO:0043307 1 0.966
monocyte extravasation GO:0035696 2 0.966
neutrophil chemotaxis GO:0030593 36 0.965
Mouse
neutrophil migration GO:1990266 37 0.965
Mouse
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.965
regulation of interleukin 1 secretion GO:0050704 15 0.964
Mouse
inflammatory cell apoptotic process GO:0006925 11 0.964
Mouse
response to lipopolysaccharide GO:0032496 128 0.962
Mouse
alpha beta t cell proliferation GO:0046633 21 0.961
regulation of neutrophil chemotaxis GO:0090022 14 0.959
Mouse
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 5 0.958
regulation of acute inflammatory response GO:0002673 27 0.957
Mouse
modulation by symbiont of host immune response GO:0052553 1 0.957
regulation of leukocyte mediated immunity GO:0002703 104 0.957
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.957
regulation of interleukin 1 production GO:0032652 26 0.956
Mouse
lymphocyte proliferation GO:0046651 164 0.955
response to host immune response GO:0052572 3 0.954
cytokine metabolic process GO:0042107 71 0.953
positive regulation of platelet activation GO:0010572 5 0.952
regulation of innate immune response GO:0045088 91 0.948
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.948
negative regulation of eosinophil degranulation GO:0043310 1 0.944
interleukin 1 production GO:0032612 31 0.943
Mouse
leukocyte chemotaxis GO:0030595 69 0.942
acute inflammatory response GO:0002526 41 0.942
Mouse
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070430 1 0.939
cellular response to molecule of bacterial origin GO:0071219 83 0.939
positive regulation of chemotaxis GO:0050921 38 0.938
cellular response to lipid GO:0071396 145 0.938
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.937
response to host defenses GO:0052200 3 0.936
helper t cell chemotaxis GO:0035704 1 0.935
positive regulation of leukocyte proliferation GO:0070665 73 0.934
cellular response to lipopolysaccharide GO:0071222 77 0.934
regulation of type 2 immune response GO:0002828 18 0.934
cell cell recognition GO:0009988 44 0.934
Mouse
regulation of eosinophil degranulation GO:0043309 1 0.934
response to molecule of bacterial origin GO:0002237 143 0.934
Mouse
positive regulation of cell activation GO:0050867 158 0.931
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052302 1 0.931
macrophage activation GO:0042116 27 0.931
Mouse
regulation of cytokine production involved in immune response GO:0002718 26 0.930
cytokine secretion GO:0050663 72 0.930
Mouse
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070434 2 0.929
detection of molecule of bacterial origin GO:0032490 2 0.929
positive regulation of defense response GO:0031349 124 0.926
leukocyte mediated immunity GO:0002443 174 0.920
myeloid cell activation involved in immune response GO:0002275 34 0.920
divalent metal ion transport GO:0070838 172 0.919
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.918
regulation of vesicle mediated transport GO:0060627 139 0.917
defense response to other organism GO:0098542 197 0.915
response to host GO:0075136 3 0.912
regulation of neutrophil migration GO:1902622 14 0.910
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.910
positive regulation of granulocyte chemotaxis GO:0071624 12 0.908
Mouse
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.906
regulation of nucleotide binding oligomerization domain containing signaling pathway GO:0070424 3 0.905
inflammatory response to wounding GO:0090594 4 0.905
calcium ion transport GO:0006816 159 0.905
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.896
lymphocyte chemotaxis GO:0048247 10 0.895
t helper 1 type immune response GO:0042088 25 0.894
blood vessel morphogenesis GO:0048514 285 0.894
regulation of cytokine biosynthetic process GO:0042035 59 0.891
response to interferon gamma GO:0034341 34 0.890
negative regulation of regulated secretory pathway GO:1903306 7 0.887
regulation of chemotaxis GO:0050920 53 0.880
regulation of response to wounding GO:1903034 189 0.880
morphogenesis of a branching structure GO:0001763 203 0.877
Mouse
antibacterial peptide production GO:0002778 2 0.875
regulation of establishment of protein localization GO:0070201 181 0.874
Mouse
cell chemotaxis GO:0060326 81 0.874
antibacterial peptide secretion GO:0002779 1 0.873
mature dendritic cell differentiation GO:0097029 3 0.872
Mouse
regulation of cell migration GO:0030334 219 0.869
regulation of lymphocyte chemotaxis GO:1901623 6 0.869
positive regulation of coagulation GO:0050820 13 0.867
mhc class ii biosynthetic process GO:0045342 8 0.863
cellular calcium ion homeostasis GO:0006874 119 0.859
Mouse Rat
positive regulation of alpha beta t cell activation GO:0046635 39 0.858
regulation of ion homeostasis GO:2000021 64 0.852
Mouse
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 6 0.851
positive regulation of mapk cascade GO:0043410 170 0.851
Rat
negative regulation of vasculature development GO:1901343 26 0.848
response to interleukin 1 GO:0070555 11 0.848
positive regulation of phagocytosis GO:0050766 26 0.848
nitric oxide biosynthetic process GO:0006809 25 0.848
regulation of vasculature development GO:1901342 88 0.843
positive regulation of lymphocyte activation GO:0051251 140 0.840
t cell chemotaxis GO:0010818 6 0.838
immune response activating signal transduction GO:0002757 116 0.838
Mouse
positive regulation of inflammatory response GO:0050729 47 0.838
regulation of protein secretion GO:0050708 82 0.834
Mouse
ras protein signal transduction GO:0007265 77 0.833
glial cell differentiation GO:0010001 131 0.833
Mouse
positive regulation of thymocyte migration GO:2000412 2 0.832
positive regulation of interferon alpha production GO:0032727 4 0.832
interleukin 1 secretion GO:0050701 16 0.832
Mouse
sequestering of calcium ion GO:0051208 18 0.830
Mouse
myeloid leukocyte activation GO:0002274 83 0.825
positive regulation of interleukin 12 production GO:0032735 21 0.823
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.822
positive regulation of t cell costimulation GO:2000525 2 0.822
Mouse
cell activation involved in immune response GO:0002263 126 0.817
vascular endothelial growth factor production GO:0010573 13 0.816
regulation of alpha beta t cell proliferation GO:0046640 18 0.816
positive regulation of cell motility GO:2000147 116 0.815
angiogenesis GO:0001525 201 0.813
sequestering of metal ion GO:0051238 19 0.811
Mouse
positive regulation of interleukin 18 production GO:0032741 2 0.810
regulation of mhc class ii biosynthetic process GO:0045346 7 0.809
response to immune response of other organism involved in symbiotic interaction GO:0052564 3 0.801
dendritic cell dendrite assembly GO:0097026 2 0.798
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.795
regulation of cell motility GO:2000145 236 0.795
response to bacterial lipoprotein GO:0032493 4 0.790
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052345 1 0.789
cytokine production GO:0001816 319 0.784
regulation of granulocyte chemotaxis GO:0071622 17 0.779
Mouse
regulation of macrophage chemotaxis GO:0010758 8 0.779
positive regulation of cytokine production GO:0001819 174 0.773
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052263 1 0.773
adaptive immune response GO:0002250 155 0.771
divalent inorganic cation homeostasis GO:0072507 138 0.771
Mouse Rat
regulation of hypersensitivity GO:0002883 10 0.769
Mouse
positive regulation of antigen processing and presentation GO:0002579 10 0.768
Mouse
regulation of inflammatory response GO:0050727 147 0.767
chemotaxis GO:0006935 247 0.766
cdc42 protein signal transduction GO:0032488 0 0.765
induction by organism of defense response of other organism involved in symbiotic interaction GO:0052251 1 0.765
regulation of alpha beta t cell activation GO:0046634 53 0.765
regulation of secretion GO:0051046 274 0.761
regulation of interferon beta biosynthetic process GO:0045357 4 0.760
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.758
t helper 17 cell chemotaxis GO:0035705 1 0.757
t cell receptor signaling pathway GO:0050852 46 0.757
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.754
positive regulation of interferon gamma production GO:0032729 39 0.753
dendritic cell migration GO:0036336 12 0.752
Mouse
positive regulation of type i interferon production GO:0032481 14 0.749
negative regulation of immune system process GO:0002683 209 0.748
defense response to virus GO:0051607 68 0.746
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.743
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 9 0.739
modification by symbiont of host morphology or physiology GO:0044003 4 0.738
inflammatory response GO:0006954 244 0.737
positive regulation of behavior GO:0048520 40 0.737
regulation of nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070432 3 0.735
regulation of monocyte chemotaxis GO:0090025 3 0.728
rho protein signal transduction GO:0007266 32 0.726
monocyte chemotaxis GO:0002548 5 0.726
regulation of glial cell differentiation GO:0045685 41 0.725
Mouse
t cell differentiation GO:0030217 174 0.725
Mouse
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.722
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.722
regulation of interleukin 1 beta production GO:0032651 25 0.721
Mouse
dendritic cell antigen processing and presentation GO:0002468 7 0.721
Mouse
regulation of t helper 1 type immune response GO:0002825 17 0.720
immune response regulating signaling pathway GO:0002764 125 0.709
Mouse
regulation of chemokine production GO:0032642 30 0.707
regulation of vascular endothelial growth factor production GO:0010574 13 0.706
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.704
interleukin 1 beta secretion GO:0050702 16 0.703
Mouse
regulation of rho gtpase activity GO:0032319 58 0.703
interleukin 18 production GO:0032621 4 0.699
regulation of interleukin 23 production GO:0032667 2 0.699
positive regulation of hemostasis GO:1900048 10 0.698
antibiotic transport GO:0042891 1 0.696
positive regulation of b cell proliferation GO:0030890 24 0.696
positive regulation of protein secretion GO:0050714 52 0.695
positive regulation of tumor necrosis factor production GO:0032760 30 0.694
pattern recognition receptor signaling pathway GO:0002221 47 0.693
neuronal action potential GO:0019228 54 0.692
regulation of hematopoietic stem cell migration GO:2000471 1 0.691
positive regulation of neutrophil migration GO:1902624 12 0.690
Mouse
modulation by organism of defense response of other organism involved in symbiotic interaction GO:0052255 1 0.689
induction by symbiont of host immune response GO:0052559 1 0.686
positive regulation of cytokine production involved in immune response GO:0002720 19 0.682
chemokine production GO:0032602 34 0.682
ensheathment of neurons GO:0007272 76 0.679
Mouse
nitric oxide synthase biosynthetic process GO:0051767 7 0.675
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.673
membrane organization GO:0061024 245 0.673
Mouse
modulation by organism of immune response of other organism involved in symbiotic interaction GO:0052552 1 0.670
positive regulation of lymphocyte migration GO:2000403 11 0.667
small gtpase mediated signal transduction GO:0007264 97 0.667
negative regulation of blood vessel morphogenesis GO:2000181 25 0.665
positive regulation of response to wounding GO:1903036 66 0.664
granulocyte activation GO:0036230 10 0.664
regulation of protein transport GO:0051223 163 0.662
Mouse
negative regulation of angiogenesis GO:0016525 25 0.660
regulation of b cell chemotaxis GO:2000537 2 0.657
regulation of cytokine production GO:0001817 266 0.656
regulation of mapk cascade GO:0043408 248 0.653
Rat
positive regulation of chemokine production GO:0032722 22 0.648
positive regulation of t cell extravasation GO:2000409 2 0.648
regulation of t cell extravasation GO:2000407 3 0.646
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.643
Mouse
regulation of humoral immune response GO:0002920 22 0.643
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.640
Mouse
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 6 0.637
t helper 2 cell cytokine production GO:0035745 4 0.635
organophosphate catabolic process GO:0046434 232 0.632
modification of morphology or physiology of other organism GO:0035821 18 0.632
sensory perception GO:0007600 245 0.630
positive regulation of interferon beta biosynthetic process GO:0045359 3 0.629
glycoprotein biosynthetic process GO:0009101 89 0.629
Mouse
nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070431 6 0.628
exocytosis GO:0006887 121 0.621
cation transport GO:0006812 399 0.618
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.613
apoptotic signaling pathway GO:0097190 306 0.612
Mouse
cellular defense response GO:0006968 6 0.611
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.610
Mouse
negative regulation of interferon gamma production GO:0032689 18 0.607
myeloid cell differentiation GO:0030099 233 0.603
Mouse
regulation of adaptive immune response GO:0002819 90 0.602
macrophage cytokine production GO:0010934 9 0.601
positive regulation of macrophage cytokine production GO:0060907 7 0.600
regulation of rho protein signal transduction GO:0035023 71 0.598
cellular response to interferon gamma GO:0071346 25 0.588
regulation of t cell activation GO:0050863 170 0.587
tumor necrosis factor production GO:0032640 50 0.582
platelet activation GO:0030168 40 0.579
release of sequestered calcium ion into cytosol GO:0051209 42 0.578
Mouse
nitric oxide production involved in inflammatory response GO:0002537 2 0.576
positive regulation of mhc class ii biosynthetic process GO:0045348 4 0.569
sensory perception of pain GO:0019233 47 0.569
positive regulation of t helper 1 type immune response GO:0002827 12 0.568
thymocyte migration GO:0072679 2 0.565
regulation of interleukin 17 production GO:0032660 8 0.565
regulation of tumor necrosis factor production GO:0032680 49 0.564
positive regulation of kinase activity GO:0033674 155 0.563
purine ribonucleoside metabolic process GO:0046128 241 0.562
regulation of t cell proliferation GO:0042129 92 0.562
production of molecular mediator of immune response GO:0002440 103 0.558
positive regulation of epithelial cell proliferation GO:0050679 68 0.556
Mouse
regulation of interferon gamma production GO:0032649 57 0.552
regulation of system process GO:0044057 200 0.552
epithelial tube morphogenesis GO:0060562 303 0.551
Mouse
cellular response to tumor necrosis factor GO:0071356 21 0.550
myeloid cell apoptotic process GO:0033028 22 0.550
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.548
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.544
cd4 positive alpha beta t cell activation GO:0035710 45 0.544
activation of immune response GO:0002253 138 0.540
Mouse
positive regulation of glycoprotein metabolic process GO:1903020 6 0.539
Mouse
macrophage apoptotic process GO:0071888 7 0.536
Mouse
multicellular organismal signaling GO:0035637 91 0.534
regulation of blood coagulation GO:0030193 28 0.533
immunoglobulin mediated immune response GO:0016064 69 0.533
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.531
positive regulation of neuron apoptotic process GO:0043525 25 0.529
b cell proliferation GO:0042100 53 0.527
type 2 immune response GO:0042092 23 0.527
cellular metal ion homeostasis GO:0006875 151 0.526
Mouse Rat
response to oxygen levels GO:0070482 62 0.525
Rat
positive regulation of leukocyte differentiation GO:1902107 86 0.525
b cell proliferation involved in immune response GO:0002322 5 0.525
alpha beta t cell activation GO:0046631 91 0.523
erk1 and erk2 cascade GO:0070371 77 0.518
regulation of eosinophil migration GO:2000416 2 0.518
positive regulation of protein modification process GO:0031401 299 0.518
cellular nitrogen compound catabolic process GO:0044270 280 0.515
cellular divalent inorganic cation homeostasis GO:0072503 127 0.515
Mouse Rat
response to bacterial lipopeptide GO:0070339 3 0.512
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.506
positive regulation of t cell activation GO:0050870 101 0.505
interleukin 12 production GO:0032615 32 0.495
Mouse
positive regulation of acute inflammatory response GO:0002675 16 0.487
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.483
positive regulation of blood coagulation GO:0030194 10 0.483
dendritic cell differentiation GO:0097028 26 0.481
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.481
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.480
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.480
regulation of membrane potential GO:0042391 192 0.480
regulation of interleukin 2 production GO:0032663 28 0.474
regulation of phagocytosis GO:0050764 33 0.471
microglial cell activation GO:0001774 3 0.470
Mouse
chloramphenicol transport GO:0042892 1 0.470
regulation of t helper 1 cell cytokine production GO:2000554 1 0.469
regulation of protein localization GO:0032880 231 0.464
Mouse
regulation of map kinase activity GO:0043405 120 0.463
positive regulation of gtpase activity GO:0043547 85 0.460
defense response to gram positive bacterium GO:0050830 50 0.458
myd88 dependent toll like receptor signaling pathway GO:0002755 7 0.458
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.457
Mouse
cellular chemical homeostasis GO:0055082 215 0.456
Mouse Rat
guanosine containing compound catabolic process GO:1901069 144 0.454
t cell migration GO:0072678 19 0.452
positive regulation of map kinase activity GO:0043406 84 0.452
lymphocyte mediated immunity GO:0002449 139 0.451
regulation of t cell chemotaxis GO:0010819 5 0.451
positive regulation by symbiont of host defense response GO:0052509 1 0.441
hematopoietic stem cell migration GO:0035701 1 0.436
regulation of oligodendrocyte differentiation GO:0048713 23 0.435
Mouse
regulation of regulated secretory pathway GO:1903305 20 0.433
keratinocyte migration GO:0051546 3 0.433
cytokine production involved in immune response GO:0002367 34 0.430
cellular response to bacterial lipoprotein GO:0071220 3 0.426
negative regulation of cell activation GO:0050866 111 0.425
response to sterol GO:0036314 4 0.423
heterocycle catabolic process GO:0046700 280 0.423
negative t cell selection GO:0043383 13 0.421
Mouse
immunoglobulin production in mucosal tissue GO:0002426 3 0.417
metal ion homeostasis GO:0055065 189 0.415
Mouse Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.413
regulation of apoptotic signaling pathway GO:2001233 197 0.413
Mouse
regulation of b cell mediated immunity GO:0002712 37 0.410
tolerance induction GO:0002507 14 0.402
Mouse
positive regulation by organism of immune response of other organism involved in symbiotic interaction GO:0052555 1 0.399
regulation of purine nucleotide catabolic process GO:0033121 122 0.398
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.392
positive regulation of t cell chemotaxis GO:0010820 5 0.388
negative regulation of secretion GO:0051048 61 0.386
regulation of interleukin 12 production GO:0032655 30 0.385
Mouse
regulation of defense response GO:0031347 233 0.385
purine nucleoside triphosphate catabolic process GO:0009146 203 0.381
transmission of nerve impulse GO:0019226 76 0.380
regulation of mononuclear cell migration GO:0071675 6 0.379
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.379
positive regulation of interleukin 1 beta production GO:0032731 16 0.378
antigen receptor mediated signaling pathway GO:0050851 64 0.376
Mouse
interleukin 11 mediated signaling pathway GO:0038154 2 0.375
positive regulation of protein phosphorylation GO:0001934 242 0.373
negative regulation of innate immune response GO:0045824 17 0.372
Mouse
regulation of t helper 2 cell cytokine production GO:2000551 3 0.371
response to hyperoxia GO:0055093 2 0.371
Rat
cation homeostasis GO:0055080 212 0.368
Mouse Rat
negative regulation of interleukin 17 production GO:0032700 5 0.366
activation of mapk activity GO:0000187 59 0.365
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.365
interferon gamma production GO:0032609 67 0.359
reactive oxygen species biosynthetic process GO:1903409 8 0.358
interaction with host GO:0051701 22 0.358
positive regulation of glial cell differentiation GO:0045687 21 0.356
Mouse
regulation of nitric oxide biosynthetic process GO:0045428 18 0.355
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.354
Mouse
plasma membrane organization GO:0007009 90 0.353
Mouse
response to low density lipoprotein particle GO:0055098 2 0.353
regulation of purine nucleotide metabolic process GO:1900542 169 0.353
cellular ion homeostasis GO:0006873 165 0.352
Mouse Rat
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.350
signal transduction in absence of ligand GO:0038034 55 0.347
Mouse
response to transforming growth factor beta GO:0071559 88 0.341
regulation of interleukin 6 biosynthetic process GO:0045408 11 0.341
t cell activation GO:0042110 289 0.341
leukocyte degranulation GO:0043299 27 0.337
interleukin 1 beta production GO:0032611 30 0.335
Mouse
regulation of macrophage cytokine production GO:0010935 8 0.331
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.331
b cell mediated immunity GO:0019724 71 0.331
negative regulation of cytokine production GO:0001818 84 0.329
regulation of chemokine secretion GO:0090196 4 0.329
regulation of t helper 1 cell differentiation GO:0045625 7 0.328
regulation of interleukin 18 production GO:0032661 3 0.327
leukocyte proliferation GO:0070661 172 0.327
cellular homeostasis GO:0019725 240 0.326
interleukin 23 production GO:0032627 2 0.325
epithelial cell proliferation GO:0050673 174 0.323
Mouse
positive regulation by organism of defense response of other organism involved in symbiotic interaction GO:0052510 1 0.323
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.323
leukocyte apoptotic process GO:0071887 71 0.322
Mouse
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.320
nitric oxide metabolic process GO:0046209 25 0.319
interleukin 6 biosynthetic process GO:0042226 12 0.318
blood coagulation GO:0007596 76 0.318
negative regulation of interleukin 23 production GO:0032707 1 0.318
morphogenesis of a branching epithelium GO:0061138 193 0.318
Mouse
positive regulation of type 2 immune response GO:0002830 9 0.318
positive regulation of immunoglobulin production GO:0002639 28 0.317
regulation of cellular catabolic process GO:0031329 242 0.315
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.315
single organismal cell cell adhesion GO:0016337 131 0.314
cell recognition GO:0008037 83 0.314
Mouse
action potential GO:0001508 78 0.311
hypersensitivity GO:0002524 10 0.311
Mouse
i kappab phosphorylation GO:0007252 6 0.307
regulation of myeloid cell apoptotic process GO:0033032 19 0.305
Mouse
regulation of kinase activity GO:0043549 249 0.304
myotube differentiation GO:0014902 105 0.299
leukocyte cell cell adhesion GO:0007159 14 0.299
t cell selection GO:0045058 34 0.298
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.297
cellular response to bacterial lipopeptide GO:0071221 3 0.295
wound healing involved in inflammatory response GO:0002246 4 0.294
t helper 1 cell cytokine production GO:0035744 1 0.293
positive regulation of cellular component biogenesis GO:0044089 94 0.288
positive regulation of apoptotic cell clearance GO:2000427 3 0.287
cytoplasmic transport GO:0016482 234 0.285
Mouse
regulation of growth of symbiont in host GO:0044126 19 0.283
cellular response to external stimulus GO:0071496 88 0.282
positive regulation of innate immune response GO:0045089 80 0.281
response to alcohol GO:0097305 48 0.281
negative regulation of leukocyte apoptotic process GO:2000107 31 0.280
Mouse
positive regulation of secretion by cell GO:1903532 114 0.278
regulation of nucleoside metabolic process GO:0009118 130 0.278
regulation of protein complex assembly GO:0043254 83 0.277
inflammatory response to antigenic stimulus GO:0002437 30 0.276
Mouse Rat
regulation of metal ion transport GO:0010959 106 0.275
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.274
positive regulation of nucleotide binding oligomerization domain containing signaling pathway GO:0070426 2 0.273
cytokine biosynthetic process GO:0042089 68 0.270
regulation of exocytosis GO:0017157 61 0.270
antibacterial peptide biosynthetic process GO:0002780 2 0.270
ribose phosphate metabolic process GO:0019693 291 0.269
natural killer cell activation GO:0030101 44 0.269
immunological synapse formation GO:0001771 7 0.268
Mouse

Ccr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease by infectious agent DOID:0050117 0 0.652
retinal disease DOID:5679 0 0.602
retinal degeneration DOID:8466 0 0.602
sensory system disease DOID:0050155 0 0.602
disease of anatomical entity DOID:7 0 0.602
eye and adnexa disease DOID:1492 0 0.602
nervous system disease DOID:863 0 0.602
eye disease DOID:5614 0 0.602
degeneration of macula and posterior pole DOID:2007 0 0.314
macular degeneration DOID:4448 0 0.314
acquired immunodeficiency syndrome DOID:635 0 0.306
viral infectious disease DOID:934 0 0.306
human immunodeficiency virus infectious disease DOID:526 0 0.306