Mus musculus

192 known processes

Nlgn1

neuroligin 1

(Aliases: NL1,mKIAA1070,MGC107366,6330415N05Rik,BB179718)

Nlgn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.206
ion transmembrane transport GO:0034220 361 0.145
amine metabolic process GO:0009308 45 0.099
cellular amino acid metabolic process GO:0006520 103 0.094
sensory perception GO:0007600 245 0.087
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.084
regulation of cellular amino acid metabolic process GO:0006521 5 0.083
regulation of cellular ketone metabolic process GO:0010565 66 0.069
cellular amine metabolic process GO:0044106 44 0.069
membrane organization GO:0061024 245 0.065
anion transmembrane transport GO:0098656 71 0.064
nitrogen compound transport GO:0071705 271 0.060
response to organic cyclic compound GO:0014070 198 0.052
cellular ketone metabolic process GO:0042180 84 0.050
peptidyl amino acid modification GO:0018193 336 0.049
cation transport GO:0006812 399 0.046
synaptic transmission GO:0007268 329 0.046
regulation of neuron differentiation GO:0045664 281 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
stem cell differentiation GO:0048863 268 0.041
ribose phosphate metabolic process GO:0019693 291 0.041
inorganic ion transmembrane transport GO:0098660 234 0.040
positive regulation of protein modification process GO:0031401 299 0.039
axonogenesis GO:0007409 274 0.039
regulation of hydrolase activity GO:0051336 246 0.039
learning GO:0007612 98 0.039
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.039
cellular response to hormone stimulus GO:0032870 150 0.039
organonitrogen compound catabolic process GO:1901565 264 0.038
regulation of homeostatic process GO:0032844 182 0.037
purine nucleotide metabolic process GO:0006163 302 0.036
positive regulation of mapk cascade GO:0043410 170 0.036
regulation of neuron projection development GO:0010975 169 0.036
Mouse Rat
nucleoside phosphate metabolic process GO:0006753 338 0.035
regulation of organelle organization GO:0033043 289 0.035
fertilization GO:0009566 127 0.035
negative regulation of protein metabolic process GO:0051248 282 0.034
g protein coupled receptor signaling pathway GO:0007186 243 0.034
maintenance of location GO:0051235 89 0.033
regulation of membrane potential GO:0042391 192 0.032
multicellular organism growth GO:0035264 161 0.032
cellular chemical homeostasis GO:0055082 215 0.031
learning or memory GO:0007611 148 0.031
Mouse
anion transport GO:0006820 177 0.031
regulation of cell motility GO:2000145 236 0.030
stem cell development GO:0048864 219 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.029
developmental maturation GO:0021700 193 0.029
Fly
regulation of ion transport GO:0043269 215 0.029
inorganic cation transmembrane transport GO:0098662 207 0.029
gonad development GO:0008406 141 0.028
organic anion transport GO:0015711 137 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
cellular response to lipid GO:0071396 145 0.028
cation homeostasis GO:0055080 212 0.028
positive regulation of cell development GO:0010720 237 0.027
Rat
regulation of cell cycle GO:0051726 281 0.027
cellular homeostasis GO:0019725 240 0.027
metal ion homeostasis GO:0055065 189 0.027
cation transmembrane transport GO:0098655 266 0.027
macromolecule catabolic process GO:0009057 281 0.026
morphogenesis of a branching structure GO:0001763 203 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
multi multicellular organism process GO:0044706 109 0.026
Fly
organonitrogen compound biosynthetic process GO:1901566 192 0.026
nucleotide metabolic process GO:0009117 332 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
renal system development GO:0072001 225 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
response to radiation GO:0009314 165 0.025
Mouse
divalent inorganic cation transport GO:0072511 178 0.025
response to organonitrogen compound GO:0010243 246 0.025
lipid biosynthetic process GO:0008610 179 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
protein maturation GO:0051604 176 0.025
purine containing compound metabolic process GO:0072521 311 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.024
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.024
sensory perception of mechanical stimulus GO:0050954 107 0.024
cell type specific apoptotic process GO:0097285 268 0.024
endocytosis GO:0006897 168 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
cellular protein complex assembly GO:0043623 116 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
carbohydrate metabolic process GO:0005975 230 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
forebrain development GO:0030900 302 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
neuromuscular process GO:0050905 99 0.023
Mouse
male gamete generation GO:0048232 285 0.023
adult locomotory behavior GO:0008344 91 0.023
Fly
regulation of vesicle mediated transport GO:0060627 139 0.023
spermatogenesis GO:0007283 284 0.023
carbohydrate homeostasis GO:0033500 128 0.022
connective tissue development GO:0061448 179 0.022
organic acid transport GO:0015849 101 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
cell maturation GO:0048469 127 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
regulation of secretion GO:0051046 274 0.022
sequestering of calcium ion GO:0051208 18 0.022
endomembrane system organization GO:0010256 147 0.021
Fly
action potential GO:0001508 78 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
gliogenesis GO:0042063 141 0.021
Mouse
regulation of cell projection organization GO:0031344 206 0.021
Mouse Rat
mapk cascade GO:0000165 281 0.021
development of primary sexual characteristics GO:0045137 143 0.021
carboxylic acid transport GO:0046942 100 0.021
regulation of hormone levels GO:0010817 211 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
cytoplasmic transport GO:0016482 234 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
oxidation reduction process GO:0055114 342 0.020
protein catabolic process GO:0030163 221 0.020
muscle cell differentiation GO:0042692 261 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
calcium ion transport GO:0006816 159 0.020
nucleoside metabolic process GO:0009116 246 0.020
regulation of protein catabolic process GO:0042176 108 0.020
regulation of protein kinase activity GO:0045859 232 0.020
ras protein signal transduction GO:0007265 77 0.019
wnt signaling pathway GO:0016055 188 0.019
establishment of organelle localization GO:0051656 122 0.019
cognition GO:0050890 149 0.019
Mouse
metencephalon development GO:0022037 89 0.019
positive regulation of cell death GO:0010942 224 0.019
organophosphate catabolic process GO:0046434 232 0.019
steroid metabolic process GO:0008202 119 0.019
adult behavior GO:0030534 135 0.019
Fly
regulation of defense response GO:0031347 233 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
regulation of proteolysis GO:0030162 164 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
sequestering of metal ion GO:0051238 19 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
regulation of neuron death GO:1901214 134 0.019
regulation of neural precursor cell proliferation GO:2000177 70 0.019
purine nucleoside metabolic process GO:0042278 241 0.018
male sex differentiation GO:0046661 109 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
regulation of mapk cascade GO:0043408 248 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
amino acid transport GO:0006865 61 0.018
divalent metal ion transport GO:0070838 172 0.018
neuron death GO:0070997 154 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
pallium development GO:0021543 120 0.018
positive regulation of nervous system development GO:0051962 221 0.018
negative regulation of molecular function GO:0044092 258 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
cytokine production GO:0001816 319 0.017
digestive tract development GO:0048565 190 0.017
regulation of binding GO:0051098 111 0.017
peptide transport GO:0015833 133 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
amino acid transmembrane transport GO:0003333 37 0.017
neuron projection guidance GO:0097485 141 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of protein maturation GO:1903317 96 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
chromatin organization GO:0006325 206 0.017
blood vessel morphogenesis GO:0048514 285 0.017
immune effector process GO:0002252 321 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
negative regulation of nervous system development GO:0051961 156 0.017
rhythmic process GO:0048511 174 0.017
regulation of cell migration GO:0030334 219 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
glial cell differentiation GO:0010001 131 0.017
Mouse
microtubule based process GO:0007017 236 0.017
protein localization to membrane GO:0072657 108 0.016
innate immune response GO:0045087 157 0.016
nucleotide catabolic process GO:0009166 217 0.016
regulation of secretion by cell GO:1903530 249 0.016
nuclear division GO:0000280 158 0.016
dephosphorylation GO:0016311 129 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
heterocycle catabolic process GO:0046700 280 0.016
regulation of kinase activity GO:0043549 249 0.016
protein polymerization GO:0051258 57 0.016
sensory perception of sound GO:0007605 97 0.016
lipid localization GO:0010876 126 0.016
regulation of peptide transport GO:0090087 91 0.016
digestive system development GO:0055123 200 0.016
exocytosis GO:0006887 121 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
neuron apoptotic process GO:0051402 142 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
apoptotic signaling pathway GO:0097190 306 0.015
negative regulation of protein modification process GO:0031400 163 0.015
cellular lipid metabolic process GO:0044255 323 0.015
neural precursor cell proliferation GO:0061351 121 0.015
skeletal system development GO:0001501 356 0.015
regulation of metal ion transport GO:0010959 106 0.015
aromatic compound catabolic process GO:0019439 286 0.015
purine containing compound catabolic process GO:0072523 213 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
negative regulation of cell development GO:0010721 169 0.015
oocyte axis specification GO:0007309 2 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
protein ubiquitination GO:0016567 171 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
regulation of peptidase activity GO:0052547 96 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
lateral inhibition GO:0046331 1 0.014
spermatid differentiation GO:0048515 115 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
Mouse Rat
protein processing GO:0016485 163 0.014
regulation of protein transport GO:0051223 163 0.014
neuron migration GO:0001764 122 0.014
adult walking behavior GO:0007628 41 0.014
Fly
cellular response to organic cyclic compound GO:0071407 87 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
response to growth factor GO:0070848 198 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
organelle fission GO:0048285 170 0.014
chromatin modification GO:0016568 187 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
regulation of ion homeostasis GO:2000021 64 0.014
response to nutrient levels GO:0031667 109 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
associative learning GO:0008306 61 0.013
Mouse
response to steroid hormone GO:0048545 56 0.013
locomotory behavior GO:0007626 195 0.013
Mouse Fly
gland development GO:0048732 330 0.013
regulation of protein complex assembly GO:0043254 83 0.013
neuronal action potential GO:0019228 54 0.013
response to monosaccharide GO:0034284 67 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
glucose homeostasis GO:0042593 128 0.013
cell adhesion GO:0007155 329 0.013
urogenital system development GO:0001655 261 0.013
t cell activation GO:0042110 289 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of protein localization GO:0032880 231 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
negative regulation of immune system process GO:0002683 209 0.013
negative regulation of homeostatic process GO:0032845 71 0.013
circulatory system process GO:0003013 197 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
oocyte construction GO:0007308 2 0.013
dendrite development GO:0016358 115 0.013
Mouse Rat
amide transport GO:0042886 138 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
muscle system process GO:0003012 141 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of actin filament based process GO:0032970 99 0.013
cellular response to monosaccharide stimulus GO:0071326 47 0.013
positive regulation of cell motility GO:2000147 116 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
negative regulation of organelle organization GO:0010639 90 0.012
skin development GO:0043588 220 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
organelle localization GO:0051640 179 0.012
regulation of inflammatory response GO:0050727 147 0.012
midgut development GO:0007494 4 0.012
telencephalon development GO:0021537 186 0.012
nucleoside catabolic process GO:0009164 206 0.012
response to acid chemical GO:0001101 111 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
placenta development GO:0001890 140 0.012
regulation of cell cycle process GO:0010564 160 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
skeletal system morphogenesis GO:0048705 203 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
regionalization GO:0003002 337 0.011
response to lipopolysaccharide GO:0032496 128 0.011
chemotaxis GO:0006935 247 0.011
germ cell development GO:0007281 185 0.011
regulation of protein processing GO:0070613 96 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
negative regulation of neuron death GO:1901215 98 0.011
cerebellum development GO:0021549 77 0.011
cell growth GO:0016049 130 0.011
regulation of transferase activity GO:0051338 263 0.011
stem cell proliferation GO:0072089 117 0.011
response to drug GO:0042493 75 0.011
cellular response to hexose stimulus GO:0071331 47 0.011
response to peptide GO:1901652 136 0.011
positive regulation of organelle organization GO:0010638 128 0.011
cellular response to carbohydrate stimulus GO:0071322 50 0.011
negative regulation of hormone metabolic process GO:0032351 4 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of cellular component size GO:0032535 121 0.011
social behavior GO:0035176 21 0.011
Mouse Fly
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
fat cell differentiation GO:0045444 160 0.011
respiratory system development GO:0060541 190 0.011
inflammatory response GO:0006954 244 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
glycoprotein metabolic process GO:0009100 116 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
cellular ion homeostasis GO:0006873 165 0.011
response to oxygen levels GO:0070482 62 0.011
tube formation GO:0035148 140 0.011
establishment of vesicle localization GO:0051650 81 0.010
transmission of nerve impulse GO:0019226 76 0.010
plasma membrane organization GO:0007009 90 0.010
vesicle localization GO:0051648 86 0.010
lipid transport GO:0006869 98 0.010
positive regulation of defense response GO:0031349 124 0.010
mitotic cell cycle GO:0000278 195 0.010
sterol homeostasis GO:0055092 45 0.010
multicellular organismal response to stress GO:0033555 62 0.010
peptidyl serine modification GO:0018209 83 0.010
immune response activating signal transduction GO:0002757 116 0.010
mucopolysaccharide metabolic process GO:1903510 25 0.010
regulation of cell activation GO:0050865 289 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
regulation of response to drug GO:2001023 2 0.010
erythrocyte differentiation GO:0030218 88 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.010
negative regulation of endothelial cell migration GO:0010596 4 0.010
negative regulation of hydrolase activity GO:0051346 71 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
male anatomical structure morphogenesis GO:0090598 4 0.010
inter male aggressive behavior GO:0002121 3 0.010
Fly
cell division GO:0051301 120 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
small molecule biosynthetic process GO:0044283 132 0.010
intracellular protein transport GO:0006886 204 0.010
Rat
positive regulation of growth GO:0045927 104 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
meiotic nuclear division GO:0007126 115 0.010

Nlgn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011
central nervous system disease DOID:331 0 0.011
musculoskeletal system disease DOID:17 0 0.010