Mus musculus

27 known processes

Wdr35

WD repeat domain 35

(Aliases: KIAA1336,mKIAA1336,4930459M12Rik,4931430C06)

Wdr35 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium morphogenesis GO:0060271 102 0.759
cilium assembly GO:0042384 81 0.752
intraciliary retrograde transport GO:0035721 3 0.367
Human
cellular component assembly involved in morphogenesis GO:0010927 139 0.287
organelle assembly GO:0070925 177 0.251
intraciliary transport GO:0042073 9 0.117
Human
smoothened signaling pathway GO:0007224 105 0.093
nucleobase containing small molecule metabolic process GO:0055086 352 0.077
purine nucleoside triphosphate metabolic process GO:0009144 226 0.077
camera type eye development GO:0043010 266 0.070
microtubule based movement GO:0007018 84 0.067
Human
transmembrane transport GO:0055085 412 0.060
purine containing compound metabolic process GO:0072521 311 0.059
cytoplasmic transport GO:0016482 234 0.055
purine nucleotide metabolic process GO:0006163 302 0.055
male gamete generation GO:0048232 285 0.054
spermatogenesis GO:0007283 284 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.053
cellular amine metabolic process GO:0044106 44 0.052
ribose phosphate metabolic process GO:0019693 291 0.052
purine ribonucleotide metabolic process GO:0009150 290 0.050
nucleoside metabolic process GO:0009116 246 0.047
ribonucleoside metabolic process GO:0009119 245 0.046
cytoskeleton dependent intracellular transport GO:0030705 50 0.045
Human
glycosyl compound metabolic process GO:1901657 246 0.045
amine metabolic process GO:0009308 45 0.045
nucleoside triphosphate metabolic process GO:0009141 230 0.043
nucleotide catabolic process GO:0009166 217 0.043
nucleotide metabolic process GO:0009117 332 0.042
organophosphate catabolic process GO:0046434 232 0.041
microtubule based process GO:0007017 236 0.041
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
ribonucleotide metabolic process GO:0009259 291 0.041
sensory organ morphogenesis GO:0090596 242 0.040
microtubule based transport GO:0010970 50 0.039
Human
establishment of protein localization to organelle GO:0072594 118 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
organic cyclic compound catabolic process GO:1901361 295 0.037
carbohydrate derivative catabolic process GO:1901136 231 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
cellular lipid metabolic process GO:0044255 323 0.036
protein localization to organelle GO:0033365 185 0.035
macromolecule catabolic process GO:0009057 281 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
organonitrogen compound catabolic process GO:1901565 264 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
photoreceptor cell differentiation GO:0046530 52 0.034
aromatic compound catabolic process GO:0019439 286 0.034
retina development in camera type eye GO:0060041 119 0.033
regionalization GO:0003002 337 0.033
morphogenesis of embryonic epithelium GO:0016331 159 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
limb development GO:0060173 166 0.033
protein catabolic process GO:0030163 221 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
cellular ketone metabolic process GO:0042180 84 0.031
nucleoside triphosphate catabolic process GO:0009143 205 0.031
photoreceptor cell development GO:0042461 40 0.031
membrane organization GO:0061024 245 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
ribonucleoside catabolic process GO:0042454 206 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
modification dependent macromolecule catabolic process GO:0043632 133 0.030
renal system development GO:0072001 225 0.030
nitrogen compound transport GO:0071705 271 0.029
appendage development GO:0048736 166 0.029
glycosyl compound catabolic process GO:1901658 206 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
single organismal cell cell adhesion GO:0016337 131 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
microtubule cytoskeleton organization GO:0000226 157 0.027
heterocycle catabolic process GO:0046700 280 0.027
nonmotile primary cilium assembly GO:0035058 8 0.027
embryonic organ morphogenesis GO:0048562 276 0.027
sensory perception GO:0007600 245 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
urogenital system development GO:0001655 261 0.026
cellular protein catabolic process GO:0044257 155 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
cell type specific apoptotic process GO:0097285 268 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
protein modification by small protein conjugation GO:0032446 187 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
cell adhesion GO:0007155 329 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
actin filament based movement GO:0030048 23 0.024
cation transmembrane transport GO:0098655 266 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
spermatid differentiation GO:0048515 115 0.023
purine containing compound catabolic process GO:0072523 213 0.023
protein localization to membrane GO:0072657 108 0.023
epithelial tube formation GO:0072175 130 0.023
gtp metabolic process GO:0046039 144 0.023
dna metabolic process GO:0006259 303 0.023
skin development GO:0043588 220 0.023
neural tube formation GO:0001841 108 0.023
olfactory learning GO:0008355 2 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
spermatid development GO:0007286 108 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
regulation of cell motility GO:2000145 236 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
germ cell development GO:0007281 185 0.022
ion transmembrane transport GO:0034220 361 0.022
cation transport GO:0006812 399 0.022
negative regulation of molecular function GO:0044092 258 0.022
myosin filament organization GO:0031033 3 0.022
neural tube development GO:0021915 160 0.022
regulation of smoothened signaling pathway GO:0008589 58 0.022
kidney development GO:0001822 213 0.021
guanosine containing compound metabolic process GO:1901068 144 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
intracellular protein transport GO:0006886 204 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
endomembrane system organization GO:0010256 147 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
eye photoreceptor cell differentiation GO:0001754 41 0.021
regulation of homeostatic process GO:0032844 182 0.021
digestive tract morphogenesis GO:0048546 147 0.021
skeletal system development GO:0001501 356 0.020
establishment or maintenance of cell polarity GO:0007163 86 0.020
appendage morphogenesis GO:0035107 149 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
wnt signaling pathway GO:0016055 188 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
digestive system development GO:0055123 200 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
protein refolding GO:0042026 1 0.020
regulation of protein localization GO:0032880 231 0.020
ras protein signal transduction GO:0007265 77 0.020
mitotic cell cycle process GO:1903047 159 0.020
mitotic cell cycle GO:0000278 195 0.020
regulation of protein transport GO:0051223 163 0.019
embryonic epithelial tube formation GO:0001838 130 0.019
regulation of cell migration GO:0030334 219 0.019
embryonic limb morphogenesis GO:0030326 126 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
muscle system process GO:0003012 141 0.019
epithelial cell proliferation GO:0050673 174 0.019
response to growth factor GO:0070848 198 0.019
positive regulation of cell development GO:0010720 237 0.019
response to organonitrogen compound GO:0010243 246 0.019
muscle cell differentiation GO:0042692 261 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
axonogenesis GO:0007409 274 0.018
cellular homeostasis GO:0019725 240 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
regulation of cell activation GO:0050865 289 0.018
embryonic appendage morphogenesis GO:0035113 126 0.018
limb morphogenesis GO:0035108 149 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
nucleoside catabolic process GO:0009164 206 0.018
sequestering of calcium ion GO:0051208 18 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
striated muscle myosin thick filament assembly GO:0071688 1 0.018
eye photoreceptor cell development GO:0042462 31 0.018
protein ubiquitination GO:0016567 171 0.017
positive regulation of protein modification process GO:0031401 299 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
establishment of organelle localization GO:0051656 122 0.017
hindbrain development GO:0030902 128 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
tube formation GO:0035148 140 0.017
dephosphorylation GO:0016311 129 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
adult behavior GO:0030534 135 0.016
epidermis development GO:0008544 187 0.016
regulation of hydrolase activity GO:0051336 246 0.016
regulation of intracellular transport GO:0032386 159 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
lipid biosynthetic process GO:0008610 179 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
cellular ion homeostasis GO:0006873 165 0.016
myosin filament assembly GO:0031034 2 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
inflammatory response GO:0006954 244 0.016
digestive tract development GO:0048565 190 0.016
primary neural tube formation GO:0014020 95 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
epithelial tube morphogenesis GO:0060562 303 0.015
gastrulation GO:0007369 116 0.015
regulation of cell cycle GO:0051726 281 0.015
small molecule biosynthetic process GO:0044283 132 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
transmission of nerve impulse GO:0019226 76 0.015
locomotory behavior GO:0007626 195 0.015
metencephalon development GO:0022037 89 0.015
spinal cord development GO:0021510 81 0.015
regulation of transmembrane transport GO:0034762 128 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
embryonic digit morphogenesis GO:0042733 56 0.015
organelle localization GO:0051640 179 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
striated muscle tissue development GO:0014706 293 0.015
regulation of cell projection organization GO:0031344 206 0.015
regulation of organelle organization GO:0033043 289 0.015
atp metabolic process GO:0046034 75 0.015
epithelial cell development GO:0002064 159 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
regulation of anatomical structure size GO:0090066 178 0.014
regulation of membrane potential GO:0042391 192 0.014
mitochondrion organization GO:0007005 134 0.014
positive regulation of protein transport GO:0051222 93 0.014
developmental maturation GO:0021700 193 0.014
protein targeting GO:0006605 143 0.014
carbohydrate metabolic process GO:0005975 230 0.014
muscle tissue development GO:0060537 308 0.014
fat cell differentiation GO:0045444 160 0.014
tissue homeostasis GO:0001894 115 0.014
respiratory system development GO:0060541 190 0.014
chemotaxis GO:0006935 247 0.014
protein maturation GO:0051604 176 0.014
morphogenesis of a polarized epithelium GO:0001738 37 0.014
forebrain development GO:0030900 302 0.014
regulation of cytokine production GO:0001817 266 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
apoptotic signaling pathway GO:0097190 306 0.014
blood vessel morphogenesis GO:0048514 285 0.014
gtp catabolic process GO:0006184 143 0.014
immune effector process GO:0002252 321 0.014
multicellular organismal signaling GO:0035637 91 0.014
muscle contraction GO:0006936 101 0.013
maintenance of location GO:0051235 89 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
intracellular mrna localization GO:0008298 4 0.013
regulation of hormone levels GO:0010817 211 0.013
mitotic cytokinesis GO:0000281 4 0.013
cellular response to lipid GO:0071396 145 0.013
oocyte axis specification GO:0007309 2 0.013
cellular protein complex assembly GO:0043623 116 0.013
response to light stimulus GO:0009416 135 0.013
neuronal action potential GO:0019228 54 0.013
metal ion homeostasis GO:0055065 189 0.013
response to transforming growth factor beta GO:0071559 88 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cellular chemical homeostasis GO:0055082 215 0.013
protein import GO:0017038 101 0.013
divalent inorganic cation transport GO:0072511 178 0.013
tube closure GO:0060606 91 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
action potential GO:0001508 78 0.013
circulatory system process GO:0003013 197 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
t cell activation GO:0042110 289 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
multicellular organism growth GO:0035264 161 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
actin cytoskeleton organization GO:0030036 220 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
glycerolipid metabolic process GO:0046486 122 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cell substrate adhesion GO:0031589 130 0.012
regulation of binding GO:0051098 111 0.012
plasma membrane organization GO:0007009 90 0.012
stem cell differentiation GO:0048863 268 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
apical constriction GO:0003383 4 0.012
telencephalon development GO:0021537 186 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
mesodermal cell migration GO:0008078 4 0.012
response to organic cyclic compound GO:0014070 198 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
protein import into nucleus GO:0006606 95 0.012
homeostasis of number of cells GO:0048872 210 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
placenta development GO:0001890 140 0.012
regulation of defense response GO:0031347 233 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
regulation of system process GO:0044057 200 0.012
organelle fission GO:0048285 170 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
peptidyl amino acid modification GO:0018193 336 0.012
sequestering of metal ion GO:0051238 19 0.012
substantia nigra development GO:0021762 2 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of transferase activity GO:0051338 263 0.012
bone development GO:0060348 120 0.012
extracellular structure organization GO:0043062 148 0.012
cerebellar cortex development GO:0021695 48 0.012
regulation of secretion by cell GO:1903530 249 0.012
innate immune response GO:0045087 157 0.012
regulation of metal ion transport GO:0010959 106 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
substrate dependent cell migration cell extension GO:0006930 4 0.012
cell growth GO:0016049 130 0.011
regulation of mapk cascade GO:0043408 248 0.011
single organism cell adhesion GO:0098602 156 0.011
left right pattern formation GO:0060972 23 0.011
ameboidal type cell migration GO:0001667 128 0.011
regulation of t cell activation GO:0050863 170 0.011
skeletal system morphogenesis GO:0048705 203 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of response to wounding GO:1903034 189 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
peptidyl serine modification GO:0018209 83 0.011
regulation of secretion GO:0051046 274 0.011
neuron death GO:0070997 154 0.011
cofactor metabolic process GO:0051186 80 0.011
positive regulation of cell motility GO:2000147 116 0.011
learning GO:0007612 98 0.011
cerebellum development GO:0021549 77 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
ear development GO:0043583 200 0.011
regulation of protein maturation GO:1903317 96 0.011
oocyte construction GO:0007308 2 0.011
cation homeostasis GO:0055080 212 0.011
single organism nuclear import GO:1902593 95 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
rna interference GO:0016246 2 0.011
nuclear transport GO:0051169 139 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
negative regulation of nervous system development GO:0051961 156 0.011
leukocyte differentiation GO:0002521 342 0.011
peptide transport GO:0015833 133 0.011
notch signaling pathway GO:0007219 71 0.011
negative regulation of organelle organization GO:0010639 90 0.011
regulation of protein binding GO:0043393 60 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.010
carbohydrate homeostasis GO:0033500 128 0.010
double strand break repair GO:0006302 48 0.010
positive regulation of binding GO:0051099 49 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
neural tube closure GO:0001843 90 0.010
negative regulation of protein modification process GO:0031400 163 0.010
regulation of ion transport GO:0043269 215 0.010
angiogenesis GO:0001525 201 0.010
nucleus organization GO:0006997 45 0.010
skeletal muscle organ development GO:0060538 163 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
regulation of multi organism process GO:0043900 111 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
regulation of cell cycle process GO:0010564 160 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
anion transport GO:0006820 177 0.010
glucose homeostasis GO:0042593 128 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.010
response to lipopolysaccharide GO:0032496 128 0.010
regulation of cellular response to stress GO:0080135 159 0.010
hormone secretion GO:0046879 128 0.010
stem cell development GO:0048864 219 0.010
cytokine production GO:0001816 319 0.010
dna repair GO:0006281 107 0.010
regulation of cilium assembly GO:1902017 7 0.010

Wdr35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
cancer DOID:162 0 0.021
musculoskeletal system disease DOID:17 0 0.020
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
central nervous system disease DOID:331 0 0.015
retinal disease DOID:5679 0 0.012
eye disease DOID:5614 0 0.012
brain disease DOID:936 0 0.011
retinal degeneration DOID:8466 0 0.011
immune system disease DOID:2914 0 0.010
connective tissue disease DOID:65 0 0.010