Mus musculus

32 known processes

Glrx3

glutaredoxin 3

(Aliases: Txnl2,PICOT)

Glrx3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.616
modification dependent macromolecule catabolic process GO:0043632 133 0.471
apoptotic signaling pathway GO:0097190 306 0.315
cellular protein catabolic process GO:0044257 155 0.313
ubiquitin dependent protein catabolic process GO:0006511 129 0.243
modification dependent protein catabolic process GO:0019941 133 0.222
transmembrane transport GO:0055085 412 0.178
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.160
proteasomal protein catabolic process GO:0010498 98 0.150
protein catabolic process GO:0030163 221 0.146
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.138
regulation of protein catabolic process GO:0042176 108 0.119
regulation of proteasomal protein catabolic process GO:0061136 46 0.114
cellular macromolecule catabolic process GO:0044265 206 0.109
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.109
macromolecule catabolic process GO:0009057 281 0.107
regulation of cellular catabolic process GO:0031329 242 0.103
regulation of apoptotic signaling pathway GO:2001233 197 0.099
male gamete generation GO:0048232 285 0.097
dna metabolic process GO:0006259 303 0.095
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.094
protein maturation GO:0051604 176 0.092
negative regulation of protein metabolic process GO:0051248 282 0.086
regulation of cellular protein catabolic process GO:1903362 61 0.085
regulation of ion transport GO:0043269 215 0.082
spindle assembly involved in mitosis GO:0090307 4 0.081
heterocycle catabolic process GO:0046700 280 0.077
regulation of protein stability GO:0031647 52 0.076
negative regulation of molecular function GO:0044092 258 0.075
regulation of proteolysis GO:0030162 164 0.074
protein processing GO:0016485 163 0.072
positive regulation of cell death GO:0010942 224 0.066
protein modification by small protein conjugation or removal GO:0070647 207 0.064
negative regulation of cellular catabolic process GO:0031330 47 0.062
regulation of ion transmembrane transport GO:0034765 119 0.061
telencephalon development GO:0021537 186 0.056
purine ribonucleotide metabolic process GO:0009150 290 0.056
cell fate commitment GO:0045165 210 0.055
camera type eye development GO:0043010 266 0.054
energy derivation by oxidation of organic compounds GO:0015980 77 0.054
cytoplasmic microtubule organization GO:0031122 14 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
regulation of dna binding GO:0051101 39 0.051
actin cytoskeleton organization GO:0030036 220 0.051
positive regulation of apoptotic process GO:0043065 217 0.051
regulation of binding GO:0051098 111 0.050
regulation of transmembrane transport GO:0034762 128 0.050
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.048
fertilization GO:0009566 127 0.047
peptidyl amino acid modification GO:0018193 336 0.046
regulation of hydrolase activity GO:0051336 246 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
regulation of membrane potential GO:0042391 192 0.042
microtubule cytoskeleton organization GO:0000226 157 0.042
negative regulation of proteolysis GO:0045861 74 0.042
organelle fission GO:0048285 170 0.040
regulation of endopeptidase activity GO:0052548 89 0.040
purine containing compound metabolic process GO:0072521 311 0.040
cytokinetic process GO:0032506 2 0.038
negative regulation of protein catabolic process GO:0042177 36 0.037
regulation of protein maturation GO:1903317 96 0.037
negative regulation of protein maturation GO:1903318 79 0.036
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.036
regulation of transporter activity GO:0032409 57 0.035
ketone catabolic process GO:0042182 3 0.035
lateral inhibition GO:0046331 1 0.034
alpha amino acid metabolic process GO:1901605 59 0.034
oocyte construction GO:0007308 2 0.034
forebrain development GO:0030900 302 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
ribose phosphate metabolic process GO:0019693 291 0.032
sperm egg recognition GO:0035036 37 0.031
small molecule biosynthetic process GO:0044283 132 0.029
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
nucleotide metabolic process GO:0009117 332 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
regulation of protein processing GO:0070613 96 0.027
germ cell development GO:0007281 185 0.027
divalent metal ion transport GO:0070838 172 0.027
positive regulation of hydrolase activity GO:0051345 148 0.026
negative regulation of protein processing GO:0010955 79 0.026
response to oxygen levels GO:0070482 62 0.026
negative regulation of cellular protein catabolic process GO:1903363 22 0.026
cellular respiration GO:0045333 38 0.025
citrate metabolic process GO:0006101 3 0.024
regulation of cell cycle GO:0051726 281 0.024
spermatogenesis GO:0007283 284 0.024
mitochondrial electron transport nadh to ubiquinone GO:0006120 4 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.023
protein refolding GO:0042026 1 0.023
intrinsic apoptotic signaling pathway GO:0097193 132 0.023
positive regulation of ion transport GO:0043270 65 0.023
nuclear transport GO:0051169 139 0.023
response to inorganic substance GO:0010035 96 0.023
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.022
negative regulation of necroptotic process GO:0060546 9 0.022
mitotic cell cycle process GO:1903047 159 0.022
nuclear division GO:0000280 158 0.022
neuron apoptotic process GO:0051402 142 0.022
positive regulation of programmed cell death GO:0043068 218 0.021
cellularization GO:0007349 1 0.021
membrane organization GO:0061024 245 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
regulation of establishment of protein localization GO:0070201 181 0.020
mitotic cell cycle GO:0000278 195 0.020
ion transmembrane transport GO:0034220 361 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
striated muscle tissue development GO:0014706 293 0.020
oocyte anterior posterior axis specification GO:0007314 2 0.019
cation transport GO:0006812 399 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
interleukin 8 production GO:0032637 4 0.019
muscle tissue development GO:0060537 308 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
transcription from rna polymerase i promoter GO:0006360 13 0.018
response to radiation GO:0009314 165 0.018
gonad development GO:0008406 141 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
hindbrain development GO:0030902 128 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
protein localization to nucleus GO:0034504 121 0.018
lateral ventricle development GO:0021670 11 0.018
calcium ion transmembrane transport GO:0070588 85 0.018
stress activated mapk cascade GO:0051403 80 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
spermatid differentiation GO:0048515 115 0.017
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.017
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.017
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
cell recognition GO:0008037 83 0.017
generation of precursor metabolites and energy GO:0006091 103 0.017
divalent inorganic cation transport GO:0072511 178 0.017
cation transmembrane transport GO:0098655 266 0.017
regulation of metal ion transport GO:0010959 106 0.017
extracellular matrix organization GO:0030198 147 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
protein stabilization GO:0050821 25 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
neuron neuron synaptic transmission GO:0007270 69 0.016
amine metabolic process GO:0009308 45 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
regulation of cysteine type endopeptidase activity GO:2000116 65 0.016
heart process GO:0003015 94 0.016
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.016
epithelial cell proliferation GO:0050673 174 0.016
cell type specific apoptotic process GO:0097285 268 0.016
leukocyte migration GO:0050900 124 0.016
negative regulation of binding GO:0051100 39 0.015
regulation of removal of superoxide radicals GO:2000121 4 0.015
nitrogen compound transport GO:0071705 271 0.015
rna splicing via endonucleolytic cleavage and ligation GO:0000394 1 0.015
regulation of defense response GO:0031347 233 0.015
multicellular organismal signaling GO:0035637 91 0.015
blood circulation GO:0008015 195 0.015
regulation of cell motility GO:2000145 236 0.015
single fertilization GO:0007338 82 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
protein folding GO:0006457 28 0.015
calcium ion transport GO:0006816 159 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
alcohol metabolic process GO:0006066 116 0.015
nucleocytoplasmic transport GO:0006913 139 0.014
negative regulation of cell development GO:0010721 169 0.014
protein ubiquitination GO:0016567 171 0.014
actomyosin structure organization GO:0031032 56 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
positive regulation of atpase activity GO:0032781 3 0.014
development of primary male sexual characteristics GO:0046546 88 0.014
regulation of protein ubiquitination GO:0031396 52 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.014
positive regulation of protein modification process GO:0031401 299 0.014
response to oxygen radical GO:0000305 16 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
response to organonitrogen compound GO:0010243 246 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
histone monoubiquitination GO:0010390 3 0.013
regulation of muscle system process GO:0090257 80 0.013
cellular lipid metabolic process GO:0044255 323 0.013
regulation of multi organism process GO:0043900 111 0.013
sperm mitochondrion organization GO:0030382 2 0.013
regulation of hormone levels GO:0010817 211 0.013
cellular amino acid biosynthetic process GO:0008652 22 0.013
nucleotide catabolic process GO:0009166 217 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
determination of adult lifespan GO:0008340 11 0.013
cartilage development GO:0051216 140 0.013
regulation of cell activation GO:0050865 289 0.013
response to hypoxia GO:0001666 58 0.012
dna integrity checkpoint GO:0031570 28 0.012
single organism nuclear import GO:1902593 95 0.012
thioester metabolic process GO:0035383 19 0.012
sperm individualization GO:0007291 1 0.012
transmission of nerve impulse GO:0019226 76 0.012
chromatin modification GO:0016568 187 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
cell cell recognition GO:0009988 44 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
pallium development GO:0021543 120 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
organic acid biosynthetic process GO:0016053 86 0.012
microtubule based process GO:0007017 236 0.012
negative regulation of protein modification process GO:0031400 163 0.012
respiratory system development GO:0060541 190 0.012
gtp catabolic process GO:0006184 143 0.012
genitalia development GO:0048806 37 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
oocyte axis specification GO:0007309 2 0.011
protein targeting GO:0006605 143 0.011
respiratory tube development GO:0030323 167 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of cell cycle process GO:0010564 160 0.011
cellular response to oxygen radical GO:0071450 14 0.011
mitochondrial transport GO:0006839 36 0.011
response to peptide GO:1901652 136 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of system process GO:0044057 200 0.011
response to light stimulus GO:0009416 135 0.011
protein localization to organelle GO:0033365 185 0.011
cellular amine metabolic process GO:0044106 44 0.011
negative regulation of immune system process GO:0002683 209 0.011
response to growth factor GO:0070848 198 0.011
positive regulation of transmembrane transport GO:0034764 29 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
positive regulation of proteolysis GO:0045862 85 0.011
neural crest cell fate commitment GO:0014034 1 0.011
wound healing GO:0042060 157 0.011
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
oxidation reduction process GO:0055114 342 0.011
cellular ketone metabolic process GO:0042180 84 0.011
fatty acid metabolic process GO:0006631 121 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of kinase activity GO:0043549 249 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
histone modification GO:0016570 159 0.010
endomembrane system organization GO:0010256 147 0.010
regulation of stress activated mapk cascade GO:0032872 69 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
regulation of cell migration GO:0030334 219 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
digestive system development GO:0055123 200 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
mitochondrion organization GO:0007005 134 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
cytoplasmic transport GO:0016482 234 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
male sex differentiation GO:0046661 109 0.010
skin development GO:0043588 220 0.010
urogenital system development GO:0001655 261 0.010
regulation of protein binding GO:0043393 60 0.010

Glrx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.033
disease of anatomical entity DOID:7 0 0.033
musculoskeletal system disease DOID:17 0 0.033
myopathy DOID:423 0 0.014
muscle tissue disease DOID:66 0 0.014