|
|
muscle cell development
|
GO:0055001 |
133 |
0.757
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.708
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.702
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.700
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.682
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.631
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.609
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.584
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.571
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.531
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.525
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.523
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.506
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.483
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.477
|
Fly |
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.470
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.466
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.465
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.461
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.459
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.457
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.428
|
|
|
|
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
|
GO:0014808 |
12 |
0.419
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.409
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.389
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.368
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.366
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.361
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.350
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.348
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.335
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.333
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.332
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.324
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.323
|
|
|
|
calcium ion transport from endoplasmic reticulum to cytosol
|
GO:1903514 |
12 |
0.305
|
|
|
|
regulation of cardiac muscle contraction by calcium ion signaling
|
GO:0010882 |
9 |
0.304
|
|
|
|
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
|
GO:0010880 |
10 |
0.303
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.301
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.296
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.292
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.289
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.287
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.287
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.283
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.282
|
Yeast |
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.280
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.274
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.271
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.265
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.257
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.251
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.247
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.238
|
Yeast |
|
|
heart process
|
GO:0003015 |
94 |
0.238
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.234
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.231
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.230
|
Yeast |
|
|
regulation of skeletal muscle adaptation
|
GO:0014733 |
12 |
0.229
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.226
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.223
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.219
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.211
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.210
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.204
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.203
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.193
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.192
|
Yeast |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.190
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.187
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.186
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.183
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.175
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.175
|
Yeast |
|
|
sarcomere organization
|
GO:0045214 |
24 |
0.175
|
|
|
|
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
|
GO:0010881 |
7 |
0.174
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.173
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.170
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.170
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.168
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.168
|
Fly |
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.166
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
25 |
0.166
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.165
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.163
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.163
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.163
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.155
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.149
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.148
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.148
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.147
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.146
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.145
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
4 |
0.144
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.142
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.142
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.141
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.137
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.132
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.132
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.129
|
|
|
|
endoplasmic reticulum to cytosol transport
|
GO:1903513 |
12 |
0.128
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.126
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.125
|
Fly |
|
|
regulation of skeletal muscle contraction
|
GO:0014819 |
3 |
0.122
|
|
|
|
regulation of heart rate
|
GO:0002027 |
36 |
0.121
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.121
|
Yeast |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.119
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.118
|
|
|
|
transition between fast and slow fiber
|
GO:0014883 |
9 |
0.117
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.115
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.112
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.108
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.107
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.105
|
Mouse |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.104
|
Worm |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.101
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.098
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.096
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.096
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.096
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.095
|
Yeast |
|
|
neuron migration
|
GO:0001764 |
122 |
0.095
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.094
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.093
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.092
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.092
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.091
|
Mouse |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.090
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
4 |
0.087
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.087
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.086
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.086
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.084
|
|
|
|
response to inactivity
|
GO:0014854 |
4 |
0.082
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.081
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.081
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.081
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.080
|
|
|
|
sa node cell to atrial cardiac muscle cell signalling
|
GO:0086018 |
4 |
0.079
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.079
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.079
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.078
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.076
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.075
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.075
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.075
|
|
|
|
striated muscle adaptation
|
GO:0014888 |
26 |
0.075
|
|
|
|
cardiac conduction
|
GO:0061337 |
17 |
0.074
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
16 |
0.074
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.074
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.073
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.073
|
Yeast |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.072
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.072
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.072
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.072
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.071
|
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
31 |
0.071
|
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.069
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.069
|
Yeast |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.069
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.069
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.069
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.068
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.067
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.067
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.066
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.066
|
|
|
|
positive regulation of calcium ion transmembrane transporter activity
|
GO:1901021 |
8 |
0.066
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.066
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.066
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.066
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.066
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.065
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.064
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.064
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.064
|
Fly |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.064
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.063
|
Worm Fly |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.063
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.063
|
Yeast |
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.062
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.062
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.062
|
|
|
|
sa node cell action potential
|
GO:0086015 |
4 |
0.062
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
39 |
0.061
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.061
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
20 |
0.061
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.060
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.060
|
|
|
|
response to ischemia
|
GO:0002931 |
14 |
0.060
|
|
|
|
skeletal muscle adaptation
|
GO:0043501 |
16 |
0.060
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.060
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.059
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.059
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.058
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.058
|
|
|
|
regulation of calcium ion transmembrane transport
|
GO:1903169 |
20 |
0.058
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.058
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.058
|
|
|
|
cellular response to calcium ion
|
GO:0071277 |
14 |
0.058
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.058
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.058
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.058
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.057
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.056
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.056
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
7 |
0.056
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.056
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.056
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.056
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.055
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.055
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.054
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.054
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.053
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.053
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.053
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.053
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
17 |
0.053
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.053
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.052
|
Yeast |
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.052
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.052
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.052
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.052
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.052
|
|
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.051
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.051
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.051
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.050
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.050
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.050
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.049
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.049
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.049
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.049
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.048
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.048
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.048
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.048
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.048
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.048
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.047
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.047
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.047
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.047
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.047
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.046
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.046
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.046
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.046
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.046
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.046
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.046
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.046
|
|
|
|
potassium ion homeostasis
|
GO:0055075 |
4 |
0.046
|
|
|
|
cell communication involved in cardiac conduction
|
GO:0086065 |
9 |
0.045
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.045
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.045
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.045
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.045
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.045
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.045
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.044
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
29 |
0.044
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.044
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.044
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
6 |
0.044
|
|
|
|
regulation of inward rectifier potassium channel activity
|
GO:1901979 |
1 |
0.044
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.044
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.044
|
|
|
|
membrane depolarization during sa node cell action potential
|
GO:0086046 |
2 |
0.044
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.043
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.043
|
|
|
|
regulation of acetylcholine secretion neurotransmission
|
GO:0014056 |
2 |
0.043
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.043
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.043
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.042
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.042
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
50 |
0.042
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.042
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.042
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.042
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.042
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.041
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.041
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.041
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.041
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.041
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.041
|
|
|
|
regulation of heart rate by chemical signal
|
GO:0003062 |
4 |
0.040
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.040
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.040
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.040
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.040
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.040
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.040
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.040
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.039
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.039
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.039
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.039
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.039
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.039
|
Fly |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.038
|
Mouse |
|
|
male anatomical structure morphogenesis
|
GO:0090598 |
4 |
0.038
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.038
|
|
|
|
learning
|
GO:0007612 |
98 |
0.038
|
|
|
|
regulation of sarcomere organization
|
GO:0060297 |
4 |
0.038
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.038
|
|
|
|
positive regulation of cardiac muscle contraction
|
GO:0060452 |
2 |
0.038
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.038
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.038
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.038
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.037
|
Worm |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.037
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.037
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.037
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.037
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.037
|
|
|
|
mitral valve development
|
GO:0003174 |
4 |
0.037
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.036
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.036
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.036
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.036
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.036
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.036
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.035
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.035
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.035
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.035
|
|
|
|
cardiac myofibril assembly
|
GO:0055003 |
12 |
0.035
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.035
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.035
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.035
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.035
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.035
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.035
|
|
|
|
positive regulation of mechanoreceptor differentiation
|
GO:0045633 |
1 |
0.035
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
58 |
0.034
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.034
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.034
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.034
|
|
|
|
response to calcium ion
|
GO:0051592 |
20 |
0.034
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.034
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.034
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.034
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.033
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.033
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.033
|
|
|
|
ventricular cardiac myofibril assembly
|
GO:0055005 |
3 |
0.033
|
|
|
|
l glutamate import into cell
|
GO:1990123 |
3 |
0.033
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.033
|
|
|
|
specification of organ identity
|
GO:0010092 |
30 |
0.033
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.033
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.033
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.033
|
|
|
|
l glutamate uptake involved in synaptic transmission
|
GO:0051935 |
3 |
0.033
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.033
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.033
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.033
|
|
|
|
atp catabolic process
|
GO:0006200 |
55 |
0.032
|
|
|
|
ventricular cardiac muscle tissue morphogenesis
|
GO:0055010 |
32 |
0.032
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.032
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.032
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.032
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.032
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.032
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.032
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.032
|
|
|
|
skeletal muscle thin filament assembly
|
GO:0030240 |
2 |
0.032
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.032
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.032
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.032
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.032
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.031
|
|
|
|
norepinephrine transport
|
GO:0015874 |
2 |
0.031
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.031
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.031
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.031
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.031
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.031
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.031
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.031
|
Yeast |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.031
|
Mouse Worm |
|
|
exocytosis
|
GO:0006887 |
121 |
0.031
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.031
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.031
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.031
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.031
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.031
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.031
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.030
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.030
|
Yeast |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.030
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.030
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
24 |
0.030
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.030
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.030
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.030
|
Yeast |
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.030
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.030
|
|
|
|
cardiac cell development
|
GO:0055006 |
41 |
0.030
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.030
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.030
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.030
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.030
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.030
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.029
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.029
|
Yeast |
|
|
negative regulation of potassium ion transport
|
GO:0043267 |
7 |
0.029
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.029
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.029
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.029
|
|
|
|
cell cell signaling involved in lung development
|
GO:0060495 |
1 |
0.029
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.029
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.029
|
|
|
|
acetate ester transport
|
GO:1901374 |
2 |
0.029
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.029
|
Mouse |
|
|
peripheral nervous system neuron axonogenesis
|
GO:0048936 |
3 |
0.029
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.029
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.029
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.029
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.029
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.028
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.028
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.028
|
|
|
|
positive regulation of striated muscle contraction
|
GO:0045989 |
3 |
0.028
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.028
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
54 |
0.028
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.028
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.028
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.028
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.028
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.028
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.028
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.028
|
|
|
|
adult walking behavior
|
GO:0007628 |
41 |
0.028
|
|
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.028
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.028
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.028
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.027
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.027
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.027
|
|
|
|
regulation of oxidative phosphorylation uncoupler activity
|
GO:2000275 |
3 |
0.027
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.027
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
11 |
0.027
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.027
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.027
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.027
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.027
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.027
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.027
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.027
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.027
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
38 |
0.027
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.027
|
|
|
|
amino acid uptake involved in synaptic transmission
|
GO:0051933 |
3 |
0.027
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.027
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.027
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.026
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.026
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.026
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.026
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.026
|
|
|
|
positive regulation of heart rate
|
GO:0010460 |
10 |
0.026
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.026
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.026
|
|
|
|
regulation of white fat cell proliferation
|
GO:0070350 |
2 |
0.026
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.026
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
28 |
0.026
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.026
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.025
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.025
|
|
|
|
skeletal muscle myosin thick filament assembly
|
GO:0030241 |
1 |
0.025
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.025
|
|
|
|
lung proximal distal axis specification
|
GO:0061115 |
1 |
0.025
|
|
|
|
membrane repolarization
|
GO:0086009 |
7 |
0.025
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.025
|
|