|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.999
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.998
|
|
|
|
regulation of epidermal cell division
|
GO:0010482 |
3 |
0.998
|
Mouse |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.998
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.997
|
Worm Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.997
|
Worm |
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.996
|
Mouse |
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.994
|
|
|
|
aggresome assembly
|
GO:0070842 |
2 |
0.993
|
Yeast |
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.991
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.988
|
Worm Fly |
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.987
|
Fly |
|
|
synapse organization
|
GO:0050808 |
125 |
0.986
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.983
|
|
|
|
keratinocyte development
|
GO:0003334 |
10 |
0.979
|
Mouse |
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.976
|
Human Mouse |
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.975
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.974
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.969
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.965
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.964
|
Worm |
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.964
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.959
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.958
|
Worm |
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.958
|
Worm |
|
|
muscle system process
|
GO:0003012 |
141 |
0.955
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.954
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.950
|
Zebrafish Worm |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.949
|
Worm Fly |
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.948
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.945
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.943
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.926
|
|
|
|
retinal cone cell development
|
GO:0046549 |
8 |
0.920
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.920
|
Yeast |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.917
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.915
|
Human Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.914
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.913
|
Yeast Fly |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.911
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.908
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
19 |
0.903
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
7 |
0.901
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.899
|
|
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
1 |
0.897
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.893
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.889
|
|
|
|
positive regulation of epidermal cell differentiation
|
GO:0045606 |
6 |
0.889
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.887
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.885
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.884
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.883
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.881
|
|
|
|
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051439 |
1 |
0.881
|
Yeast |
|
|
inclusion body assembly
|
GO:0070841 |
3 |
0.880
|
Yeast |
|
|
cell division
|
GO:0051301 |
120 |
0.880
|
Yeast Mouse Worm |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.877
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.876
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.874
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.867
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.866
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.860
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.858
|
Zebrafish |
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
3 |
0.855
|
Yeast |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.853
|
Fly |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.853
|
Fly |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.853
|
Mouse |
|
|
organelle localization
|
GO:0051640 |
179 |
0.848
|
Worm |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.847
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.846
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.846
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.844
|
|
|
|
mitochondrial calcium ion homeostasis
|
GO:0051560 |
7 |
0.844
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.843
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.841
|
|
|
|
regulation of membrane repolarization
|
GO:0060306 |
7 |
0.840
|
|
|
|
epidermal cell division
|
GO:0010481 |
3 |
0.839
|
Mouse |
|
|
terminal button organization
|
GO:0072553 |
3 |
0.836
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.833
|
Yeast |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.832
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
11 |
0.830
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.822
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.822
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.822
|
|
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
2 |
0.818
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.812
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.811
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.810
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.806
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.804
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.796
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.794
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.792
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.792
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.792
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.791
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.786
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.783
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.781
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
15 |
0.778
|
Worm |
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.772
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.770
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.764
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.762
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.761
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.758
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.757
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.752
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.750
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.750
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.745
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.743
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.738
|
|
|
|
nucleus localization
|
GO:0051647 |
20 |
0.737
|
Worm |
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.736
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.735
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.731
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.724
|
Yeast Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.719
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.718
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.717
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.715
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.712
|
Worm |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.709
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.709
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.708
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.708
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.702
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.701
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.696
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.694
|
Fly |
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.691
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.685
|
Mouse |
|
|
cognition
|
GO:0050890 |
149 |
0.683
|
Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.683
|
|
|
|
cytokinesis
|
GO:0000910 |
17 |
0.681
|
|
|
|
asymmetric cell division
|
GO:0008356 |
8 |
0.672
|
Worm |
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
2 |
0.672
|
Human Mouse |
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.671
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.670
|
|
|
|
sarcomere organization
|
GO:0045214 |
24 |
0.667
|
|
|
|
positive regulation of epidermis development
|
GO:0045684 |
13 |
0.666
|
Mouse |
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.662
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.659
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.659
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.653
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.649
|
Fly |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
7 |
0.649
|
Yeast |
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.637
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.631
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.629
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.628
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.628
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.615
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.611
|
|
|
|
neurofilament cytoskeleton organization
|
GO:0060052 |
10 |
0.609
|
|
|
|
negative regulation of actin filament depolymerization
|
GO:0030835 |
9 |
0.609
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.607
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.604
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.603
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.594
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.592
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.588
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.586
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.581
|
|
|
|
membrane repolarization
|
GO:0086009 |
7 |
0.581
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.579
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.579
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.578
|
Fly |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.577
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.577
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.574
|
Worm |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
19 |
0.574
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.574
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.573
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.573
|
Mouse |
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.565
|
Yeast |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.564
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.562
|
|
|
|
zygote asymmetric cell division
|
GO:0010070 |
2 |
0.562
|
Worm |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.560
|
Human Mouse |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.557
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.549
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
10 |
0.543
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.538
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.535
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.535
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.532
|
Yeast |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.532
|
Human Yeast Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.524
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.521
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.521
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.518
|
|
|
|
negative regulation of potassium ion transmembrane transporter activity
|
GO:1901017 |
3 |
0.516
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.514
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.513
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.511
|
Yeast |
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.507
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.507
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.504
|
Worm |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.504
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.500
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.498
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.495
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.495
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.495
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.489
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.485
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.482
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.479
|
|
|
|
regulation of peroxidase activity
|
GO:2000468 |
1 |
0.477
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.475
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.474
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
49 |
0.473
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.471
|
|
|
|
establishment of mitochondrion localization
|
GO:0051654 |
4 |
0.471
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.471
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.470
|
Mouse |
|
|
response to metal ion
|
GO:0010038 |
47 |
0.468
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.467
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.460
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.456
|
Human Yeast Mouse |
|
|
sensory perception of umami taste
|
GO:0050917 |
4 |
0.455
|
|
|
|
peripheral nervous system axon regeneration
|
GO:0014012 |
2 |
0.453
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.452
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.451
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
1 |
0.450
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.450
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.448
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.448
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.448
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.447
|
Mouse |
|
|
hippocampus development
|
GO:0021766 |
52 |
0.443
|
Mouse |
|
|
asymmetric protein localization
|
GO:0008105 |
11 |
0.442
|
Worm |
|
|
cell cell junction assembly
|
GO:0007043 |
27 |
0.440
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.435
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
1 |
0.430
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.428
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.428
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.426
|
|
|
|
negative regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030948 |
6 |
0.424
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.420
|
|
|
|
retinal cone cell differentiation
|
GO:0042670 |
8 |
0.419
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.418
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
9 |
0.416
|
Yeast |
|
|
glial cell development
|
GO:0021782 |
54 |
0.415
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.414
|
Yeast Worm |
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.409
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.407
|
Yeast Mouse Worm |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.405
|
|
|
|
glucuronate metabolic process
|
GO:0019585 |
2 |
0.399
|
|
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
3 |
0.395
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.394
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.390
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.387
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.384
|
Yeast Mouse Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.383
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.380
|
Mouse |
|
|
oogenesis
|
GO:0048477 |
56 |
0.379
|
Fly |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.376
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.370
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.367
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.367
|
|
|
|
axon regeneration
|
GO:0031103 |
12 |
0.365
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.364
|
Mouse |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.363
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.362
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.362
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.360
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.357
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.356
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.356
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.355
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.354
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.353
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
11 |
0.352
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.352
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.350
|
|
|
|
cellular response to ethanol
|
GO:0071361 |
3 |
0.348
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.345
|
|
|
|
protein localization to synapse
|
GO:0035418 |
11 |
0.342
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.340
|
|
|
|
peripheral nervous system neuron axonogenesis
|
GO:0048936 |
3 |
0.340
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.339
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.338
|
Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.337
|
Yeast |
|
|
detection of visible light
|
GO:0009584 |
14 |
0.335
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.328
|
|
|
|
protein stabilization
|
GO:0050821 |
25 |
0.327
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.327
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.326
|
Yeast Worm |
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.325
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.325
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.324
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.322
|
Worm |
|
|
establishment of skin barrier
|
GO:0061436 |
14 |
0.320
|
Mouse |
|
|
cofactor biosynthetic process
|
GO:0051188 |
41 |
0.318
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.312
|
Yeast |
|
|
fibroblast migration
|
GO:0010761 |
21 |
0.311
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.304
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
80 |
0.302
|
|
|
|
regulation of water loss via skin
|
GO:0033561 |
16 |
0.301
|
Mouse |
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.300
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
9 |
0.299
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.299
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.298
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.297
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
4 |
0.296
|
Human Mouse |
|
|
regulation of synaptic vesicle recycling
|
GO:1903421 |
2 |
0.294
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
5 |
0.294
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.293
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
9 |
0.293
|
Human Mouse |
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.292
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.290
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.290
|
Mouse |
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.286
|
Mouse |
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
2 |
0.284
|
|
|
|
phototransduction
|
GO:0007602 |
17 |
0.284
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.283
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.282
|
|
|
|
dense core granule biogenesis
|
GO:0061110 |
1 |
0.281
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.281
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.278
|
Yeast |
|
|
vesicle localization
|
GO:0051648 |
86 |
0.278
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.277
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.274
|
|
|
|
protein export from nucleus
|
GO:0006611 |
20 |
0.274
|
Mouse |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.273
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.272
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.271
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.270
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.268
|
|
|
|
positive regulation of schwann cell proliferation
|
GO:0010625 |
1 |
0.268
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.268
|
Fly |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.268
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.267
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.267
|
Fly |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.266
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.264
|
|
|
|
maintenance of presynaptic active zone structure
|
GO:0048790 |
1 |
0.263
|
|
|
|
regulation of dendritic spine morphogenesis
|
GO:0061001 |
17 |
0.260
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.260
|
Worm |
|
|
sensory perception
|
GO:0007600 |
245 |
0.259
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.258
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.258
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.257
|
Yeast |
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.251
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.250
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.249
|
Mouse |
|
|
negative regulation of keratinocyte proliferation
|
GO:0010839 |
7 |
0.248
|
Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.248
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.248
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.248
|
|
|
|
keratinization
|
GO:0031424 |
9 |
0.247
|
Mouse |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.245
|
|
|
|
negative regulation of peroxidase activity
|
GO:2000469 |
1 |
0.244
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.243
|
Worm |
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
17 |
0.243
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.243
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
11 |
0.243
|
Mouse |
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
24 |
0.240
|
|
|
|
visual perception
|
GO:0007601 |
52 |
0.239
|
|
|
|
nuclear migration
|
GO:0007097 |
6 |
0.239
|
Worm |
|
|
nuclear division
|
GO:0000280 |
158 |
0.238
|
Yeast Worm |
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.237
|
|
|
|
cell fate determination
|
GO:0001709 |
32 |
0.237
|
Worm Fly |
|
|
dna replication initiation
|
GO:0006270 |
5 |
0.236
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.236
|
|
|
|
uronic acid metabolic process
|
GO:0006063 |
2 |
0.236
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.233
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.233
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.232
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.231
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.231
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.229
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.227
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.226
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.225
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.225
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.221
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.219
|
Yeast Worm |
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.217
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.216
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.216
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.216
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.215
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.214
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.213
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.208
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.208
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.208
|
|
|
|
sa node cell action potential
|
GO:0086015 |
4 |
0.206
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.205
|
|
|
|
apical junction assembly
|
GO:0043297 |
15 |
0.204
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.204
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.204
|
|
|
|
establishment of glial blood brain barrier
|
GO:0060857 |
2 |
0.204
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
13 |
0.202
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
16 |
0.202
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.202
|
|
|
|
centrosome organization
|
GO:0051297 |
26 |
0.202
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
15 |
0.202
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.202
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.199
|
|
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.196
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.196
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.196
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
14 |
0.196
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.195
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.193
|
|
|
|
regulation of protein kinase a signaling
|
GO:0010738 |
6 |
0.193
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
10 |
0.193
|
Yeast |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.191
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.190
|
Worm |
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.189
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.188
|
|
|
|
intracellular distribution of mitochondria
|
GO:0048312 |
1 |
0.187
|
|
|
|
spindle organization
|
GO:0007051 |
28 |
0.186
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.186
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.185
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.185
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.185
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.184
|
Mouse |
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
5 |
0.184
|
Fly |
|
|
keratinocyte proliferation
|
GO:0043616 |
21 |
0.183
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.183
|
Yeast Worm Fly |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.183
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.181
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.181
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.180
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
3 |
0.180
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.179
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.179
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.178
|
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.177
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.177
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.177
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.176
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.175
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.171
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.170
|
|
|
|
sa node cell to atrial cardiac muscle cell signalling
|
GO:0086018 |
4 |
0.169
|
|
|
|
regulation of protein deubiquitination
|
GO:0090085 |
1 |
0.169
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.168
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.168
|
|
|
|
response to vitamin d
|
GO:0033280 |
3 |
0.168
|
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.166
|
|
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
9 |
0.165
|
|
|
|
exit from mitosis
|
GO:0010458 |
3 |
0.164
|
Yeast |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.164
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.163
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.163
|
Fly |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.161
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.161
|
|
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
15 |
0.160
|
Mouse |
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.160
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.160
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.159
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.158
|
|
|
|
synaptic vesicle priming
|
GO:0016082 |
8 |
0.157
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.157
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.156
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.156
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.152
|
Yeast |
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.152
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.151
|
Fly |
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.151
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
2 |
0.151
|
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.150
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.150
|
Mouse |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.149
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.149
|
|
|
|
actin modification
|
GO:0030047 |
1 |
0.147
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.146
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.143
|
|
|
|
t cell tolerance induction
|
GO:0002517 |
6 |
0.142
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.141
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
28 |
0.141
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.141
|
|
|
|
regulation of terminal button organization
|
GO:2000331 |
1 |
0.141
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.140
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.139
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.139
|
|
|
|
locomotory exploration behavior
|
GO:0035641 |
10 |
0.139
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.139
|
|
|
|
regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030947 |
14 |
0.139
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.139
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.138
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.138
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.138
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.138
|
|
