Mus musculus

76 known processes

Pcm1

pericentriolar material 1

(Aliases: 2600002H09Rik,9430077F19Rik,MGC170660,C030044G17Rik)

Pcm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 81 0.747
Human
cilium morphogenesis GO:0060271 102 0.728
Human
eye photoreceptor cell development GO:0042462 31 0.683
eye photoreceptor cell differentiation GO:0001754 41 0.678
organelle assembly GO:0070925 177 0.434
Human
camera type eye development GO:0043010 266 0.215
telomere maintenance GO:0000723 19 0.213
ear development GO:0043583 200 0.172
ear morphogenesis GO:0042471 118 0.172
photoreceptor cell development GO:0042461 40 0.153
photoreceptor cell differentiation GO:0046530 52 0.148
olfactory learning GO:0008355 2 0.133
modification dependent protein catabolic process GO:0019941 133 0.133
regulation of cell cycle GO:0051726 281 0.130
protein catabolic process GO:0030163 221 0.127
nucleobase containing small molecule metabolic process GO:0055086 352 0.127
inorganic ion transmembrane transport GO:0098660 234 0.114
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.106
development of primary sexual characteristics GO:0045137 143 0.101
regulation of chromosome organization GO:0033044 83 0.099
digestive system development GO:0055123 200 0.099
protein processing GO:0016485 163 0.095
ubiquitin dependent protein catabolic process GO:0006511 129 0.095
modification dependent macromolecule catabolic process GO:0043632 133 0.093
nucleotide catabolic process GO:0009166 217 0.091
protein modification by small protein conjugation or removal GO:0070647 207 0.089
cation transmembrane transport GO:0098655 266 0.087
tube formation GO:0035148 140 0.081
macromolecule catabolic process GO:0009057 281 0.080
embryonic organ morphogenesis GO:0048562 276 0.079
covalent chromatin modification GO:0016569 163 0.077
multicellular organism growth GO:0035264 161 0.075
leukocyte differentiation GO:0002521 342 0.072
cellular component assembly involved in morphogenesis GO:0010927 139 0.071
Human
forebrain development GO:0030900 302 0.069
regionalization GO:0003002 337 0.069
regulation of transcription by chromatin organization GO:0034401 0 0.068
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.067
cerebellum development GO:0021549 77 0.067
inorganic cation transmembrane transport GO:0098662 207 0.066
sensory organ morphogenesis GO:0090596 242 0.066
regulation of cell cycle process GO:0010564 160 0.065
protein ubiquitination GO:0016567 171 0.065
regulation of protein maturation GO:1903317 96 0.065
positive regulation of organelle organization GO:0010638 128 0.064
digestive tract development GO:0048565 190 0.062
nucleoside triphosphate catabolic process GO:0009143 205 0.061
ossification GO:0001503 216 0.061
chemotaxis GO:0006935 247 0.059
hindbrain development GO:0030902 128 0.059
dna recombination GO:0006310 92 0.058
intracellular protein transport GO:0006886 204 0.056
Human
limb development GO:0060173 166 0.056
cytoskeleton dependent intracellular transport GO:0030705 50 0.056
Human
calcium ion transport GO:0006816 159 0.056
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.055
purine containing compound metabolic process GO:0072521 311 0.054
dna metabolic process GO:0006259 303 0.053
skeletal system development GO:0001501 356 0.053
negative regulation of proteolysis GO:0045861 74 0.052
protein localization to organelle GO:0033365 185 0.052
calcium ion transmembrane transport GO:0070588 85 0.051
cellular protein catabolic process GO:0044257 155 0.049
spermatogenesis GO:0007283 284 0.049
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.048
mitotic cell cycle process GO:1903047 159 0.048
gastrulation GO:0007369 116 0.048
organelle fission GO:0048285 170 0.046
embryonic appendage morphogenesis GO:0035113 126 0.045
protein maturation GO:0051604 176 0.043
appendage morphogenesis GO:0035107 149 0.043
purine ribonucleotide catabolic process GO:0009154 208 0.043
membrane organization GO:0061024 245 0.043
amine metabolic process GO:0009308 45 0.042
regulation of organelle organization GO:0033043 289 0.042
nucleoside monophosphate metabolic process GO:0009123 85 0.040
urogenital system development GO:0001655 261 0.039
purine nucleoside monophosphate catabolic process GO:0009128 58 0.039
regulation of protein processing GO:0070613 96 0.038
metencephalon development GO:0022037 89 0.038
microtubule based movement GO:0007018 84 0.037
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.036
multi multicellular organism process GO:0044706 109 0.036
neuron projection guidance GO:0097485 141 0.034
gonad development GO:0008406 141 0.034
hematopoietic progenitor cell differentiation GO:0002244 143 0.034
neural tube development GO:0021915 160 0.034
cellular amine metabolic process GO:0044106 44 0.034
negative regulation of cell proliferation GO:0008285 296 0.034
protein methylation GO:0006479 81 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.034
purine nucleotide metabolic process GO:0006163 302 0.033
microtubule based process GO:0007017 236 0.033
lymphocyte differentiation GO:0030098 242 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
nucleotide metabolic process GO:0009117 332 0.033
learning or memory GO:0007611 148 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
retina development in camera type eye GO:0060041 119 0.032
appendage development GO:0048736 166 0.032
central nervous system neuron differentiation GO:0021953 162 0.031
protein targeting GO:0006605 143 0.031
cellular potassium ion transport GO:0071804 43 0.031
regulation of mitotic cell cycle phase transition GO:1901990 73 0.031
purine containing compound catabolic process GO:0072523 213 0.031
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.031
limb morphogenesis GO:0035108 149 0.030
neural precursor cell proliferation GO:0061351 121 0.030
skin development GO:0043588 220 0.029
t cell activation GO:0042110 289 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
nucleoside monophosphate catabolic process GO:0009125 59 0.029
regulation of intracellular transport GO:0032386 159 0.028
Human
organic hydroxy compound metabolic process GO:1901615 203 0.028
striated muscle tissue development GO:0014706 293 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
inner ear morphogenesis GO:0042472 101 0.028
t cell differentiation GO:0030217 174 0.028
establishment or maintenance of cell polarity GO:0007163 86 0.028
wnt signaling pathway GO:0016055 188 0.028
atp catabolic process GO:0006200 55 0.027
regulation of system process GO:0044057 200 0.027
epithelial tube formation GO:0072175 130 0.026
g1 s transition of mitotic cell cycle GO:0000082 57 0.026
segmentation GO:0035282 93 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.025
ion transmembrane transport GO:0034220 361 0.025
heart process GO:0003015 94 0.025
chromatin organization GO:0006325 206 0.025
cellular amino acid metabolic process GO:0006520 103 0.025
ras protein signal transduction GO:0007265 77 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
cellular ion homeostasis GO:0006873 165 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
positive regulation of cell death GO:0010942 224 0.024
axon guidance GO:0007411 141 0.024
cellular ketone metabolic process GO:0042180 84 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.023
nucleoside catabolic process GO:0009164 206 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
placenta development GO:0001890 140 0.023
formation of primary germ layer GO:0001704 77 0.023
embryonic limb morphogenesis GO:0030326 126 0.023
nuclear import GO:0051170 95 0.023
germ cell development GO:0007281 185 0.022
trophectodermal cell differentiation GO:0001829 21 0.022
hair cycle GO:0042633 90 0.022
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.022
microtubule polymerization or depolymerization GO:0031109 26 0.022
regulation of cell cycle phase transition GO:1901987 77 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.022
positive regulation of growth GO:0045927 104 0.022
negative regulation of protein catabolic process GO:0042177 36 0.022
renal system development GO:0072001 225 0.021
positive regulation of cell cycle process GO:0090068 61 0.021
positive regulation of chromosome organization GO:2001252 33 0.021
cellular magnesium ion homeostasis GO:0010961 3 0.021
cytoplasmic transport GO:0016482 234 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
regulation of protein catabolic process GO:0042176 108 0.021
blood circulation GO:0008015 195 0.021
regulation of cellular protein catabolic process GO:1903362 61 0.021
embryonic skeletal system development GO:0048706 120 0.021
neural tube formation GO:0001841 108 0.021
oocyte axis specification GO:0007309 2 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
somitogenesis GO:0001756 69 0.020
regulation of proteolysis GO:0030162 164 0.020
nuclear division GO:0000280 158 0.020
kidney development GO:0001822 213 0.020
negative regulation of cellular protein catabolic process GO:1903363 22 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
sensory perception GO:0007600 245 0.020
digestive tract morphogenesis GO:0048546 147 0.020
negative regulation of chromatin silencing GO:0031936 1 0.020
response to organic cyclic compound GO:0014070 198 0.020
muscle cell differentiation GO:0042692 261 0.019
transmembrane transport GO:0055085 412 0.019
positive regulation of protein modification process GO:0031401 299 0.019
divalent metal ion transport GO:0070838 172 0.019
organophosphate catabolic process GO:0046434 232 0.019
tube closure GO:0060606 91 0.019
muscle tissue development GO:0060537 308 0.018
female gamete generation GO:0007292 74 0.018
cell cycle g1 s phase transition GO:0044843 57 0.018
dna templated transcription initiation GO:0006352 13 0.018
cellular chemical homeostasis GO:0055082 215 0.018
regulation of homeostatic process GO:0032844 182 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
mitotic cell cycle GO:0000278 195 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
Human
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.018
stem cell development GO:0048864 219 0.018
bone development GO:0060348 120 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
leukocyte mediated immunity GO:0002443 174 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
cellular response to external stimulus GO:0071496 88 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
regulation of response to dna damage stimulus GO:2001020 34 0.017
regulation of cell division GO:0051302 76 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
cell division GO:0051301 120 0.016
sensory perception of sound GO:0007605 97 0.016
plasma membrane organization GO:0007009 90 0.016
meiotic cell cycle process GO:1903046 77 0.016
response to radiation GO:0009314 165 0.016
homeostasis of number of cells GO:0048872 210 0.016
cation transport GO:0006812 399 0.016
apoptotic signaling pathway GO:0097190 306 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
oocyte anterior posterior axis specification GO:0007314 2 0.016
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.016
cilium movement GO:0003341 28 0.016
fibroblast proliferation GO:0048144 35 0.015
cardiac muscle contraction GO:0060048 32 0.015
positive regulation of mitotic cell cycle GO:0045931 41 0.015
protein polymerization GO:0051258 57 0.015
primary neural tube formation GO:0014020 95 0.015
atp metabolic process GO:0046034 75 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
response to fibroblast growth factor GO:0071774 47 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
myeloid cell homeostasis GO:0002262 114 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
negative regulation of protein processing GO:0010955 79 0.015
meiotic cell cycle GO:0051321 122 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
cellular response to abiotic stimulus GO:0071214 56 0.014
cation homeostasis GO:0055080 212 0.014
blastocyst development GO:0001824 80 0.014
epidermis development GO:0008544 187 0.014
negative regulation of protein modification process GO:0031400 163 0.014
mapk cascade GO:0000165 281 0.014
dephosphorylation GO:0016311 129 0.014
aromatic compound catabolic process GO:0019439 286 0.014
pancreas development GO:0031016 57 0.014
cellular response to lipid GO:0071396 145 0.014
meiotic nuclear division GO:0007126 115 0.014
epithelial cell development GO:0002064 159 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
regulation of protein stability GO:0031647 52 0.013
determination of left right symmetry GO:0007368 80 0.013
positive regulation of dna templated transcription elongation GO:0032786 2 0.013
histone lysine methylation GO:0034968 50 0.013
skeletal system morphogenesis GO:0048705 203 0.013
cell differentiation in spinal cord GO:0021515 53 0.013
divalent inorganic cation transport GO:0072511 178 0.013
actin mediated cell contraction GO:0070252 15 0.013
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
intracellular mrna localization GO:0008298 4 0.013
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
compound eye development GO:0048749 1 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
regulation of cellular amine metabolic process GO:0033238 20 0.012
mapk export from nucleus GO:0045204 1 0.012
positive regulation of cell cycle phase transition GO:1901989 17 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
chromatin remodeling at centromere GO:0031055 2 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
oocyte construction GO:0007308 2 0.012
regulation of secretion GO:0051046 274 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
Human
response to thyroid hormone GO:0097066 2 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
somite development GO:0061053 81 0.012
regulation of chromatin organization GO:1902275 57 0.012
positive regulation of chromatin modification GO:1903310 28 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
reproductive behavior GO:0019098 32 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.011
male meiosis GO:0007140 37 0.011
positive regulation of intracellular protein transport GO:0090316 42 0.011
Human
b cell activation GO:0042113 161 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
protein acylation GO:0043543 64 0.011
regulation of translation GO:0006417 71 0.011
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.011
response to lipopolysaccharide GO:0032496 128 0.011
regulation of chromatin silencing GO:0031935 2 0.011
maintenance of protein location in nucleus GO:0051457 2 0.011
bmp signaling pathway GO:0030509 93 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of microtubule based process GO:0032886 52 0.011
heart morphogenesis GO:0003007 178 0.011
striated muscle contraction GO:0006941 45 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
heterochromatin organization GO:0070828 4 0.011
cellular homeostasis GO:0019725 240 0.011
macromolecule methylation GO:0043414 120 0.011
cell fate commitment GO:0045165 210 0.011
positive regulation of wnt signaling pathway GO:0030177 45 0.011
bone morphogenesis GO:0060349 78 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
regulation of smoothened signaling pathway GO:0008589 58 0.010
cellular response to radiation GO:0071478 28 0.010
protein modification by small protein conjugation GO:0032446 187 0.010
cell type specific apoptotic process GO:0097285 268 0.010
forebrain neuron differentiation GO:0021879 52 0.010
neural tube closure GO:0001843 90 0.010
mitotic cell cycle checkpoint GO:0007093 31 0.010
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 3 0.010
endoderm development GO:0007492 45 0.010
maintenance of location GO:0051235 89 0.010

Pcm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.048
sensory system disease DOID:0050155 0 0.027
retinal disease DOID:5679 0 0.021
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.021
cancer DOID:162 0 0.018
Human
disease of cellular proliferation DOID:14566 0 0.018
Human
organ system cancer DOID:0050686 0 0.018
Human
endocrine system disease DOID:28 0 0.017
motor neuron disease DOID:231 0 0.012
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
endocrine gland cancer DOID:170 0 0.012
Human
thyroid cancer DOID:1781 0 0.012
Human