Mus musculus

0 known processes

Edem2

ER degradation enhancer, mannosidase alpha-like 2

(Aliases: AI327354,9530090G24Rik)

Edem2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.071
glycoprotein biosynthetic process GO:0009101 89 0.062
macroautophagy GO:0016236 21 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.047
carbohydrate derivative biosynthetic process GO:1901137 183 0.045
cytoplasmic transport GO:0016482 234 0.044
peptidyl amino acid modification GO:0018193 336 0.042
alcohol metabolic process GO:0006066 116 0.040
sterol metabolic process GO:0016125 58 0.040
regulation of cytokine production GO:0001817 266 0.039
negative regulation of protein metabolic process GO:0051248 282 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
cellular amine metabolic process GO:0044106 44 0.037
ion transmembrane transport GO:0034220 361 0.036
compound eye development GO:0048749 1 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.034
regulation of cell activation GO:0050865 289 0.034
cation transport GO:0006812 399 0.034
apoptotic signaling pathway GO:0097190 306 0.033
carbohydrate metabolic process GO:0005975 230 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
cellular ketone metabolic process GO:0042180 84 0.032
protein maturation GO:0051604 176 0.031
regulation of transferase activity GO:0051338 263 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
cellular lipid metabolic process GO:0044255 323 0.030
steroid metabolic process GO:0008202 119 0.027
germ cell development GO:0007281 185 0.027
metal ion homeostasis GO:0055065 189 0.027
lysosome organization GO:0007040 21 0.026
spermatogenesis GO:0007283 284 0.026
cellular metal ion homeostasis GO:0006875 151 0.025
response to organonitrogen compound GO:0010243 246 0.025
sphingolipid metabolic process GO:0006665 45 0.025
lytic vacuole organization GO:0080171 21 0.024
response to molecule of bacterial origin GO:0002237 143 0.024
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
leukocyte differentiation GO:0002521 342 0.024
transmembrane transport GO:0055085 412 0.024
macromolecule catabolic process GO:0009057 281 0.023
Mouse Fly
regulation of cellular response to stress GO:0080135 159 0.023
divalent inorganic cation transport GO:0072511 178 0.023
organic anion transport GO:0015711 137 0.023
amine metabolic process GO:0009308 45 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.023
membrane lipid biosynthetic process GO:0046467 32 0.023
cation homeostasis GO:0055080 212 0.022
positive regulation of cell death GO:0010942 224 0.022
glycoprotein metabolic process GO:0009100 116 0.022
Mouse
positive regulation of programmed cell death GO:0043068 218 0.022
cellular response to starvation GO:0009267 57 0.022
cellular response to lipid GO:0071396 145 0.022
glycosylation GO:0070085 62 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
Mouse Fly
regulation of mapk cascade GO:0043408 248 0.022
cholesterol metabolic process GO:0008203 56 0.021
cell type specific apoptotic process GO:0097285 268 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
membrane lipid metabolic process GO:0006643 53 0.021
neuron death GO:0070997 154 0.021
mitochondrion organization GO:0007005 134 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.021
cellular homeostasis GO:0019725 240 0.020
cellular chemical homeostasis GO:0055082 215 0.020
positive regulation of cytokine production GO:0001819 174 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
negative regulation of molecular function GO:0044092 258 0.020
protein ubiquitination GO:0016567 171 0.020
carbohydrate homeostasis GO:0033500 128 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
cation transmembrane transport GO:0098655 266 0.020
response to peptide GO:1901652 136 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
lipid biosynthetic process GO:0008610 179 0.019
innate immune response GO:0045087 157 0.019
positive regulation of protein modification process GO:0031401 299 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
protein glycosylation GO:0006486 55 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
macromolecule glycosylation GO:0043413 55 0.018
cytokine production GO:0001816 319 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
regulation of ion transport GO:0043269 215 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
epidermis development GO:0008544 187 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
Mouse Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
golgi to endosome transport GO:0006895 3 0.018
cellular response to extracellular stimulus GO:0031668 81 0.018
stem cell differentiation GO:0048863 268 0.018
cellular response to nutrient levels GO:0031669 64 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
regulation of secretion by cell GO:1903530 249 0.018
regulation of defense response GO:0031347 233 0.018
vacuole organization GO:0007033 38 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
regulation of endocytosis GO:0030100 69 0.018
membrane organization GO:0061024 245 0.018
anion transport GO:0006820 177 0.018
regulation of body fluid levels GO:0050878 162 0.018
cognition GO:0050890 149 0.017
golgi vesicle transport GO:0048193 30 0.017
phagocytosis GO:0006909 66 0.017
defense response to other organism GO:0098542 197 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
small molecule biosynthetic process GO:0044283 132 0.017
response to nutrient levels GO:0031667 109 0.017
leukocyte homeostasis GO:0001776 79 0.017
male gamete generation GO:0048232 285 0.017
mapk cascade GO:0000165 281 0.017
organic acid transport GO:0015849 101 0.017
anatomical structure homeostasis GO:0060249 145 0.017
nitrogen compound transport GO:0071705 271 0.017
regulation of kinase activity GO:0043549 249 0.017
organelle assembly GO:0070925 177 0.017
glycerolipid metabolic process GO:0046486 122 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
skin development GO:0043588 220 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
regulation of protein localization GO:0032880 231 0.016
nuclear transport GO:0051169 139 0.016
regulation of proteolysis GO:0030162 164 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
macromolecule methylation GO:0043414 120 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
locomotory behavior GO:0007626 195 0.016
regulation of organelle organization GO:0033043 289 0.016
response to lipopolysaccharide GO:0032496 128 0.016
cellular response to growth factor stimulus GO:0071363 197 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
negative regulation of cell activation GO:0050866 111 0.015
dna metabolic process GO:0006259 303 0.015
homeostasis of number of cells GO:0048872 210 0.015
lymphocyte differentiation GO:0030098 242 0.015
positive regulation of kinase activity GO:0033674 155 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
endocytosis GO:0006897 168 0.015
regulation of protein kinase activity GO:0045859 232 0.015
divalent metal ion transport GO:0070838 172 0.015
lateral inhibition GO:0046331 1 0.015
sterol transport GO:0015918 38 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
nucleotide metabolic process GO:0009117 332 0.015
protein processing GO:0016485 163 0.015
protein catabolic process GO:0030163 221 0.014
Mouse Fly
production of molecular mediator of immune response GO:0002440 103 0.014
response to starvation GO:0042594 65 0.014
lymphocyte homeostasis GO:0002260 64 0.014
oxidation reduction process GO:0055114 342 0.014
negative regulation of cytokine production GO:0001818 84 0.014
regulation of hydrolase activity GO:0051336 246 0.014
ameboidal type cell migration GO:0001667 128 0.014
response to extracellular stimulus GO:0009991 127 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
immune effector process GO:0002252 321 0.014
forebrain development GO:0030900 302 0.014
learning or memory GO:0007611 148 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
Mouse Fly
t cell activation GO:0042110 289 0.014
skeletal system development GO:0001501 356 0.014
multicellular organism growth GO:0035264 161 0.013
carboxylic acid transport GO:0046942 100 0.013
glucose homeostasis GO:0042593 128 0.013
response to peptide hormone GO:0043434 127 0.013
regulation of neuron differentiation GO:0045664 281 0.013
nucleotide sugar metabolic process GO:0009225 4 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
spermatid differentiation GO:0048515 115 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
cell adhesion GO:0007155 329 0.013
gland development GO:0048732 330 0.013
cellular protein complex assembly GO:0043623 116 0.013
alpha amino acid metabolic process GO:1901605 59 0.013
leukocyte apoptotic process GO:0071887 71 0.013
single organism cell adhesion GO:0098602 156 0.013
regulation of t cell activation GO:0050863 170 0.013
stem cell development GO:0048864 219 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
purine containing compound metabolic process GO:0072521 311 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
regulation of engulfment of apoptotic cell GO:1901074 2 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
methylation GO:0032259 134 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
respiratory tube development GO:0030323 167 0.012
positive regulation of macroautophagy GO:0016239 3 0.012
vesicle localization GO:0051648 86 0.012
cilium morphogenesis GO:0060271 102 0.012
protein localization to organelle GO:0033365 185 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
regulation of protein transport GO:0051223 163 0.012
positive regulation of cell activation GO:0050867 158 0.012
aromatic compound catabolic process GO:0019439 286 0.012
amino acid transport GO:0006865 61 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
response to insulin GO:0032868 100 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of homeostatic process GO:0032844 182 0.012
protein secretion GO:0009306 111 0.012
carbohydrate transport GO:0008643 62 0.012
vesicle organization GO:0016050 60 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
positive regulation of transferase activity GO:0051347 167 0.012
regulation of lipoprotein lipase activity GO:0051004 4 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
sequestering of metal ion GO:0051238 19 0.012
regulation of secretion GO:0051046 274 0.012
activation of immune response GO:0002253 138 0.012
protein alkylation GO:0008213 81 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.011
tissue homeostasis GO:0001894 115 0.011
response to organic cyclic compound GO:0014070 198 0.011
nuclear import GO:0051170 95 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
cellular amide metabolic process GO:0043603 58 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
skeletal system morphogenesis GO:0048705 203 0.011
cellular alcohol metabolic process GO:0044107 3 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
maintenance of location GO:0051235 89 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
wound healing GO:0042060 157 0.011
regulation of adaptive immune response GO:0002819 90 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
sulfur compound metabolic process GO:0006790 100 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
response to radiation GO:0009314 165 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of hormone levels GO:0010817 211 0.011
respiratory system development GO:0060541 190 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
leukocyte proliferation GO:0070661 172 0.011
lipid homeostasis GO:0055088 63 0.011
cellular response to peptide GO:1901653 92 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
response to acid chemical GO:0001101 111 0.011
intracellular protein transport GO:0006886 204 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
myeloid cell differentiation GO:0030099 233 0.010
smoothened signaling pathway GO:0007224 105 0.010
positive regulation of defense response GO:0031349 124 0.010
protein targeting GO:0006605 143 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
synaptic transmission GO:0007268 329 0.010
response to inorganic substance GO:0010035 96 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
chromatin modification GO:0016568 187 0.010
neutral lipid metabolic process GO:0006638 57 0.010
regulation of plasma lipoprotein particle levels GO:0097006 23 0.010
lymphocyte proliferation GO:0046651 164 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
leukocyte mediated immunity GO:0002443 174 0.010
organic cyclic compound catabolic process GO:1901361 295 0.010
lipid localization GO:0010876 126 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
Mouse Fly
calcium ion transport GO:0006816 159 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
regulation of anatomical structure size GO:0090066 178 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
lipid transport GO:0006869 98 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
regulation of leukocyte apoptotic process GO:2000106 56 0.010
lipoprotein metabolic process GO:0042157 43 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010

Edem2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
central nervous system disease DOID:331 0 0.038
immune system disease DOID:2914 0 0.025
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
neurodegenerative disease DOID:1289 0 0.016
musculoskeletal system disease DOID:17 0 0.014
hematopoietic system disease DOID:74 0 0.012
dementia DOID:1307 0 0.010
disease of mental health DOID:150 0 0.010
cognitive disorder DOID:1561 0 0.010