Mus musculus

100 known processes

Trpc2

transient receptor potential cation channel, subfamily C, member 2

(Aliases: mTrp2,smTRPC2,TRPC2a,trp2,3010009O07Rik,TRPC2b,AI115608,Trrp2)

Trpc2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.140
cellular amino acid metabolic process GO:0006520 103 0.115
cellular response to gamma radiation GO:0071480 4 0.081
cellular amine metabolic process GO:0044106 44 0.080
amine metabolic process GO:0009308 45 0.066
regulation of cellular ketone metabolic process GO:0010565 66 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
regulation of cellular amine metabolic process GO:0033238 20 0.054
cellular ketone metabolic process GO:0042180 84 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.053
peptidyl amino acid modification GO:0018193 336 0.050
regulation of organelle organization GO:0033043 289 0.044
dna repair GO:0006281 107 0.043
positive regulation of macroautophagy GO:0016239 3 0.042
cellular lipid metabolic process GO:0044255 323 0.037
mitochondrion organization GO:0007005 134 0.037
dna metabolic process GO:0006259 303 0.034
mitochondrion degradation GO:0000422 3 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.034
dna recombination GO:0006310 92 0.033
regulation of protein localization GO:0032880 231 0.033
covalent chromatin modification GO:0016569 163 0.032
meiotic cell cycle process GO:1903046 77 0.032
nuclear division GO:0000280 158 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.031
positive regulation of organelle organization GO:0010638 128 0.030
regulation of apoptotic signaling pathway GO:2001233 197 0.029
signal transduction involved in dna damage checkpoint GO:0072422 3 0.029
mitotic g1 dna damage checkpoint GO:0031571 4 0.028
organelle fission GO:0048285 170 0.028
response to radiation GO:0009314 165 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
germ cell development GO:0007281 185 0.027
embryonic organ morphogenesis GO:0048562 276 0.027
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.027
cell activation involved in immune response GO:0002263 126 0.027
histone modification GO:0016570 159 0.027
leukocyte differentiation GO:0002521 342 0.026
membrane organization GO:0061024 245 0.026
chromatin modification GO:0016568 187 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
apoptotic signaling pathway GO:0097190 306 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
regulation of mapk cascade GO:0043408 248 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
lymphocyte differentiation GO:0030098 242 0.024
regulation of anatomical structure size GO:0090066 178 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
ras protein signal transduction GO:0007265 77 0.024
mitotic cell cycle process GO:1903047 159 0.024
skeletal system morphogenesis GO:0048705 203 0.023
regulation of cell cycle process GO:0010564 160 0.023
t cell activation GO:0042110 289 0.023
negative regulation of dna replication GO:0008156 4 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
b cell activation GO:0042113 161 0.022
skeletal system development GO:0001501 356 0.022
regulation of intracellular transport GO:0032386 159 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
chromatin organization GO:0006325 206 0.021
cell type specific apoptotic process GO:0097285 268 0.021
muscle tissue development GO:0060537 308 0.021
phospholipid metabolic process GO:0006644 87 0.021
intracellular protein transport GO:0006886 204 0.021
response to organonitrogen compound GO:0010243 246 0.021
epidermis development GO:0008544 187 0.021
positive regulation of protein modification process GO:0031401 299 0.020
renal system development GO:0072001 225 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
skin development GO:0043588 220 0.020
neuron death GO:0070997 154 0.020
heterocycle catabolic process GO:0046700 280 0.020
negative regulation of cell development GO:0010721 169 0.020
macromolecule catabolic process GO:0009057 281 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
multicellular organism growth GO:0035264 161 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
t cell differentiation GO:0030217 174 0.020
meiosis i GO:0007127 60 0.020
regulation of neuron differentiation GO:0045664 281 0.020
respiratory system development GO:0060541 190 0.020
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 14 0.020
regulation of cell cycle GO:0051726 281 0.020
meiotic nuclear division GO:0007126 115 0.019
limb morphogenesis GO:0035108 149 0.019
negative regulation of neuron death GO:1901215 98 0.019
negative regulation of molecular function GO:0044092 258 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
telencephalon development GO:0021537 186 0.019
transmembrane transport GO:0055085 412 0.019
response to light stimulus GO:0009416 135 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
regulation of transferase activity GO:0051338 263 0.019
spermatogenesis GO:0007283 284 0.019
nuclear transport GO:0051169 139 0.019
metencephalon development GO:0022037 89 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
morphogenesis of a polarized epithelium GO:0001738 37 0.018
cytokine production GO:0001816 319 0.018
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.018
regulation of protein transport GO:0051223 163 0.018
cation transport GO:0006812 399 0.018
purine containing compound metabolic process GO:0072521 311 0.018
establishment of tissue polarity GO:0007164 28 0.018
protein targeting GO:0006605 143 0.018
cytoplasmic transport GO:0016482 234 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
forebrain development GO:0030900 302 0.018
striated muscle tissue development GO:0014706 293 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
aromatic compound catabolic process GO:0019439 286 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
mapk cascade GO:0000165 281 0.017
regulation of neuron death GO:1901214 134 0.017
regulation of cell activation GO:0050865 289 0.017
regulation of stem cell proliferation GO:0072091 78 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
meiotic cell cycle GO:0051321 122 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
organ growth GO:0035265 117 0.017
cell division GO:0051301 120 0.017
mitotic cell cycle GO:0000278 195 0.017
inflammatory response GO:0006954 244 0.017
peptidyl tyrosine modification GO:0018212 145 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
protein import into nucleus GO:0006606 95 0.016
mitochondrial dna metabolic process GO:0032042 13 0.016
immune effector process GO:0002252 321 0.016
mitochondrial membrane organization GO:0007006 26 0.016
female sex differentiation GO:0046660 84 0.016
positive regulation of cell death GO:0010942 224 0.016
gland development GO:0048732 330 0.016
mitochondrial genome maintenance GO:0000002 15 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
protein maturation GO:0051604 176 0.016
limb development GO:0060173 166 0.016
protein localization to organelle GO:0033365 185 0.016
rho protein signal transduction GO:0007266 32 0.016
ribonucleoside catabolic process GO:0042454 206 0.015
negative regulation of nervous system development GO:0051961 156 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
single organism nuclear import GO:1902593 95 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
lymphocyte activation involved in immune response GO:0002285 93 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.015
nucleotide catabolic process GO:0009166 217 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
urogenital system development GO:0001655 261 0.015
regulation of cytokine production GO:0001817 266 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
protein import GO:0017038 101 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
positive regulation of cardiac muscle cell apoptotic process GO:0010666 3 0.015
ribose phosphate metabolic process GO:0019693 291 0.014
regulation of hydrolase activity GO:0051336 246 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
t cell activation involved in immune response GO:0002286 43 0.014
cerebellum development GO:0021549 77 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
exocytosis GO:0006887 121 0.014
protein catabolic process GO:0030163 221 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
mitochondrial transport GO:0006839 36 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
purine containing compound catabolic process GO:0072523 213 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
negative regulation of protein modification process GO:0031400 163 0.014
protein localization to nucleus GO:0034504 121 0.014
nucleoside catabolic process GO:0009164 206 0.014
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
actin filament organization GO:0007015 113 0.014
positive regulation of keratinocyte proliferation GO:0010838 4 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
male gamete generation GO:0048232 285 0.014
apoptotic mitochondrial changes GO:0008637 48 0.014
carbohydrate metabolic process GO:0005975 230 0.014
tissue remodeling GO:0048771 102 0.014
epithelial cell development GO:0002064 159 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.013
female gamete generation GO:0007292 74 0.013
digestive tract development GO:0048565 190 0.013
regulation of map kinase activity GO:0043405 120 0.013
heart morphogenesis GO:0003007 178 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.013
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.013
macromolecule deacylation GO:0098732 37 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
double strand break repair GO:0006302 48 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
smooth muscle tissue development GO:0048745 22 0.013
small molecule biosynthetic process GO:0044283 132 0.013
regulation of proteolysis GO:0030162 164 0.013
nucleotide metabolic process GO:0009117 332 0.013
regulation of organ growth GO:0046620 61 0.013
response to growth factor GO:0070848 198 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
wound healing GO:0042060 157 0.013
regulation of membrane potential GO:0042391 192 0.013
oogenesis GO:0048477 56 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
cell adhesion GO:0007155 329 0.013
positive regulation of cell activation GO:0050867 158 0.013
stem cell differentiation GO:0048863 268 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
protein deacylation GO:0035601 36 0.013
nucleoside metabolic process GO:0009116 246 0.013
purine nucleoside metabolic process GO:0042278 241 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
regulation of protein processing GO:0070613 96 0.012
limbic system development GO:0021761 72 0.012
t cell differentiation in thymus GO:0033077 77 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
positive regulation of mitochondrial membrane permeability GO:0035794 12 0.012
organophosphate catabolic process GO:0046434 232 0.012
regulation of stress activated mapk cascade GO:0032872 69 0.012
neuroblast differentiation GO:0014016 2 0.012
compound eye development GO:0048749 1 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
organelle assembly GO:0070925 177 0.012
hindbrain development GO:0030902 128 0.012
regulation of membrane permeability GO:0090559 18 0.012
cellular response to x ray GO:0071481 2 0.012
regulation of mitochondrial membrane permeability GO:0046902 17 0.012
regulation of protein complex assembly GO:0043254 83 0.012
digestive system development GO:0055123 200 0.012
regulation of cellular component size GO:0032535 121 0.012
sensory perception GO:0007600 245 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
regulation of secretion GO:0051046 274 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
regulation of jun kinase activity GO:0043506 40 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regionalization GO:0003002 337 0.012
regulation of kinase activity GO:0043549 249 0.012
cellular protein complex assembly GO:0043623 116 0.012
camera type eye development GO:0043010 266 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
blood vessel morphogenesis GO:0048514 285 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
embryonic limb morphogenesis GO:0030326 126 0.012
nuclear import GO:0051170 95 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.011
mitochondrial dna repair GO:0043504 3 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
cardiac muscle tissue development GO:0048738 130 0.011
methylation GO:0032259 134 0.011
embryonic skeletal system development GO:0048706 120 0.011
regulation of secretion by cell GO:1903530 249 0.011
protein deacetylation GO:0006476 32 0.011
sensory organ morphogenesis GO:0090596 242 0.011
microtubule based process GO:0007017 236 0.011
regulation of muscle tissue development GO:1901861 97 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
response to uv GO:0009411 44 0.011
protein polymerization GO:0051258 57 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
appendage morphogenesis GO:0035107 149 0.011
pallium development GO:0021543 120 0.011
b cell differentiation GO:0030183 78 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
response to nutrient levels GO:0031667 109 0.011
protein processing GO:0016485 163 0.011
regulation of protein kinase activity GO:0045859 232 0.011
cellular response to light stimulus GO:0071482 19 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
divalent inorganic cation transport GO:0072511 178 0.011
regulation of cellular response to stress GO:0080135 159 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
regulation of hormone levels GO:0010817 211 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
positive regulation of striated muscle cell apoptotic process GO:0010663 3 0.011
regulation of protein catabolic process GO:0042176 108 0.011
gtp metabolic process GO:0046039 144 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
establishment of planar polarity GO:0001736 28 0.011
innate immune response GO:0045087 157 0.010
myeloid cell differentiation GO:0030099 233 0.010
positive regulation of proteolysis GO:0045862 85 0.010
nitrogen compound transport GO:0071705 271 0.010
Mouse
macromolecule methylation GO:0043414 120 0.010
hair follicle development GO:0001942 85 0.010
lateral inhibition GO:0046331 1 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
cell cycle g1 s phase transition GO:0044843 57 0.010
cellular response to abiotic stimulus GO:0071214 56 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
positive regulation of stem cell proliferation GO:2000648 59 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
ossification GO:0001503 216 0.010
respiratory tube development GO:0030323 167 0.010
regulation of protein maturation GO:1903317 96 0.010
regulation of tissue remodeling GO:0034103 38 0.010
rna processing GO:0006396 105 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.010
blastocyst development GO:0001824 80 0.010
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.010

Trpc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
immune system disease DOID:2914 0 0.016
hematopoietic system disease DOID:74 0 0.016
disease of cellular proliferation DOID:14566 0 0.011
sensory system disease DOID:0050155 0 0.010