|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.931
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.915
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.898
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.881
|
|
|
|
mrna catabolic process
|
GO:0006402 |
22 |
0.850
|
|
|
|
rna catabolic process
|
GO:0006401 |
29 |
0.838
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.835
|
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
10 |
0.799
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.798
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.796
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.796
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.794
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.769
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.752
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.737
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.734
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.727
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.719
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.695
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.683
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.667
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.661
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.639
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.635
|
|
|
|
negative regulation of germinal center formation
|
GO:0002635 |
2 |
0.618
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.617
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.614
|
|
|
|
nuclear transcribed mrna catabolic process
|
GO:0000956 |
16 |
0.614
|
|
|
|
cytoplasmic mrna processing body assembly
|
GO:0033962 |
6 |
0.599
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.573
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.538
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.536
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.532
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.521
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.520
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.514
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.503
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.495
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.481
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.474
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.464
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.443
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.435
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.425
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.421
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.419
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.414
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.413
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.408
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.407
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.397
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.395
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.395
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.394
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.386
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.382
|
|
|
|
negative regulation of alpha beta t cell differentiation
|
GO:0046639 |
12 |
0.367
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.361
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.351
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.350
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.338
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.330
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.329
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.328
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.328
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.327
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.323
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.320
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.310
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.309
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.303
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.301
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.299
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.295
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.278
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.277
|
Worm |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.260
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.257
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.256
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.244
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.241
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.236
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.228
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.224
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.222
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.219
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.218
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.213
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.204
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.202
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.201
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.197
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.195
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.171
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.170
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.170
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.168
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.167
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.162
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.160
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.153
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.153
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.152
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.151
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.147
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.146
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.144
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
10 |
0.144
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.142
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.141
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.141
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.139
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.138
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.136
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.136
|
Mouse |
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.136
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.135
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.126
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.126
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.126
|
Mouse |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.122
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.121
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.121
|
Worm |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.119
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.119
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.118
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.117
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.114
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.114
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.113
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.112
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.110
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.109
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.105
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.104
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.103
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.102
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.101
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.098
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.097
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.096
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.096
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.095
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.095
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.092
|
Worm |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.092
|
Worm |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.090
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.090
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.088
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.088
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.087
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.087
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.087
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.087
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.086
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.086
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.085
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.085
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.084
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.084
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.083
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.080
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.079
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.079
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.078
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.078
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.078
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.075
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.075
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.074
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.074
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.073
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.072
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.072
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.071
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.070
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.070
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.070
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.069
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.068
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.067
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.066
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.066
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.065
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.065
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.064
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.064
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.063
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.063
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.063
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.063
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.062
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.062
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.060
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.060
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.059
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.059
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.058
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.057
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.057
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.056
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.056
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.056
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.056
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.056
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.056
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.055
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.055
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.055
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.055
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.054
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.054
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.054
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.053
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.053
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.052
|
Worm |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.052
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.052
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.052
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.052
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.052
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.052
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.052
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.052
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.051
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.051
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.051
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.051
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.050
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
6 |
0.050
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.050
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.050
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.050
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.050
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.049
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.049
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.049
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.049
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.049
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.048
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.048
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.048
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.048
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.047
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.047
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.047
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.047
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.047
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.046
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.046
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.046
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.046
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.045
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.045
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.044
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.044
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.044
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.044
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.044
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.044
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.044
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.044
|
|
|
|
nuclear transcribed mrna catabolic process deadenylation dependent decay
|
GO:0000288 |
12 |
0.044
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.044
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.043
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.043
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.043
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.043
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.043
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.043
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.043
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.042
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.042
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.042
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.042
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.042
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.042
|
|
|
|
regulation of rna stability
|
GO:0043487 |
26 |
0.042
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.041
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.041
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.041
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.041
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.041
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.040
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.040
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.040
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.040
|
|
|
|
negative regulation of activated t cell proliferation
|
GO:0046007 |
7 |
0.040
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.040
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.039
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.039
|
Worm |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.039
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.039
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.039
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.039
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.038
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.038
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.038
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.038
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.038
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.038
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.038
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.038
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.038
|
Worm |
|
|
dna modification
|
GO:0006304 |
50 |
0.038
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.038
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.037
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.036
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.036
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.036
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.036
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.035
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.035
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.035
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.035
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.035
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.034
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.034
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.034
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.034
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.034
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.034
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.034
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.034
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.034
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.034
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.033
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.033
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.033
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.033
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.033
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.033
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.033
|
|
|
|
regulation of germinal center formation
|
GO:0002634 |
10 |
0.032
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.032
|
|
|
|
negative regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043371 |
9 |
0.032
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.032
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.032
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.032
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.032
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.032
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.032
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.032
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.032
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.032
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.032
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.032
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.032
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.031
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.031
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.031
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.031
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.031
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.031
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.031
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.031
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.031
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.031
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.030
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.030
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.030
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.030
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.030
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.030
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.030
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.030
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.029
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.029
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.029
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.029
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.029
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.029
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.029
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.029
|
|
|
|
negative regulation of isotype switching
|
GO:0045829 |
4 |
0.029
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.029
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.029
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.029
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.028
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.028
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.028
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.028
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
32 |
0.028
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.028
|
|
|
|
somatic recombination of t cell receptor gene segments
|
GO:0002681 |
5 |
0.028
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.028
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.028
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.028
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.028
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.028
|
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
7 |
0.028
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.028
|
|
|
|
negative regulation of cellular senescence
|
GO:2000773 |
3 |
0.028
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.027
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.027
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.027
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.027
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.027
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.027
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.027
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.027
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.027
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.027
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.026
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.026
|
|
|
|
germline cell cycle switching mitotic to meiotic cell cycle
|
GO:0051729 |
1 |
0.026
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.026
|
|
|
|
histone deacetylation
|
GO:0016575 |
26 |
0.026
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.026
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.026
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.026
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.026
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.026
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.026
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.025
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.025
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.025
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.025
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.025
|
Worm |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.025
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.025
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.025
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.025
|
|
|
|
cell fate determination
|
GO:0001709 |
32 |
0.025
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.025
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.025
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.025
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.025
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.025
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.024
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.024
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.024
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.024
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.024
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.024
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.024
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.024
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.024
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.024
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.024
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.024
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.024
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.024
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.024
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.024
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.024
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.023
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.023
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.023
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.023
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.023
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.023
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.023
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.023
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.023
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.023
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.023
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.023
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.023
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.023
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.023
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.023
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.023
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.023
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.023
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.023
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.023
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.022
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.022
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.022
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.022
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.022
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.022
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.022
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.022
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.022
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.022
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.022
|
|
|
|
cell cycle switching
|
GO:0060184 |
1 |
0.022
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.022
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.022
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.022
|
|