Mus musculus

196 known processes

Nkx3-1

NK-3 transcription factor, locus 1 (Drosophila)

(Aliases: bagpipe,NKX3A,Nkx-3.1,Bax,NKX3.1)

Nkx3-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 276 0.658
Mouse
gland development GO:0048732 330 0.618
urogenital system development GO:0001655 261 0.592
cell adhesion GO:0007155 329 0.518
mesenchyme development GO:0060485 152 0.504
sensory organ morphogenesis GO:0090596 242 0.501
Mouse
regulation of kinase activity GO:0043549 249 0.496
Human
regulation of cellular amine metabolic process GO:0033238 20 0.455
muscle system process GO:0003012 141 0.447
bmp signaling pathway GO:0030509 93 0.440
nuclear import GO:0051170 95 0.409
angiogenesis GO:0001525 201 0.406
mitotic chromosome condensation GO:0007076 1 0.382
response to oxygen levels GO:0070482 62 0.375
Human
establishment of protein localization to organelle GO:0072594 118 0.375
locomotory behavior GO:0007626 195 0.367
regionalization GO:0003002 337 0.365
heart morphogenesis GO:0003007 178 0.351
nephron tubule morphogenesis GO:0072078 68 0.350
muscle cell differentiation GO:0042692 261 0.332
embryonic skeletal system morphogenesis GO:0048704 91 0.320
amine metabolic process GO:0009308 45 0.298
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.294
regulation of establishment of protein localization GO:0070201 181 0.293
mesenchymal cell development GO:0014031 93 0.275
neural crest cell development GO:0014032 48 0.258
forebrain development GO:0030900 302 0.256
Mouse
nucleotide biosynthetic process GO:0009165 78 0.248
axonogenesis GO:0007409 274 0.241
neuron projection guidance GO:0097485 141 0.240
stem cell development GO:0048864 219 0.240
limb morphogenesis GO:0035108 149 0.239
Mouse
nephron tubule development GO:0072080 84 0.237
cellular ketone metabolic process GO:0042180 84 0.235
morphogenesis of a branching structure GO:0001763 203 0.232
response to decreased oxygen levels GO:0036293 59 0.228
Human
epithelial tube morphogenesis GO:0060562 303 0.223
leukocyte differentiation GO:0002521 342 0.211
mapk cascade GO:0000165 281 0.209
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.208
negative regulation of immune system process GO:0002683 209 0.206
epithelial cell morphogenesis GO:0003382 41 0.204
cell type specific apoptotic process GO:0097285 268 0.197
Mouse
mesenchymal cell differentiation GO:0048762 107 0.196
steroid metabolic process GO:0008202 119 0.195
t cell activation GO:0042110 289 0.194
cell proliferation in hindbrain GO:0021534 10 0.192
protein localization to organelle GO:0033365 185 0.190
regulation of mapk cascade GO:0043408 248 0.189
synaptic transmission GO:0007268 329 0.187
regulation of protein transport GO:0051223 163 0.184
apoptotic signaling pathway GO:0097190 306 0.182
Human
cellular amine metabolic process GO:0044106 44 0.181
epithelial cell proliferation GO:0050673 174 0.179
response to acid chemical GO:0001101 111 0.177
camera type eye development GO:0043010 266 0.177
development of primary sexual characteristics GO:0045137 143 0.176
positive regulation of mapk cascade GO:0043410 170 0.173
prostate gland development GO:0030850 48 0.173
skin development GO:0043588 220 0.173
organic hydroxy compound metabolic process GO:1901615 203 0.173
stem cell differentiation GO:0048863 268 0.172
renal tubule development GO:0061326 87 0.172
ribonucleotide metabolic process GO:0009259 291 0.171
regulation of anatomical structure size GO:0090066 178 0.167
male sex differentiation GO:0046661 109 0.165
cytoplasmic transport GO:0016482 234 0.164
nuclear transport GO:0051169 139 0.164
intracellular protein transport GO:0006886 204 0.163
fertilization GO:0009566 127 0.163
cytokine production GO:0001816 319 0.153
neural tube development GO:0021915 160 0.152
nephron morphogenesis GO:0072028 69 0.151
ear morphogenesis GO:0042471 118 0.150
Mouse
retina development in camera type eye GO:0060041 119 0.150
mesonephric tubule morphogenesis GO:0072171 63 0.148
generation of ovulation cycle rhythm GO:0060112 1 0.147
positive regulation of cell cycle GO:0045787 92 0.147
Human
circulatory system process GO:0003013 197 0.147
multi multicellular organism process GO:0044706 109 0.146
ureteric bud morphogenesis GO:0060675 62 0.144
renal tubule morphogenesis GO:0061333 72 0.143
cellular response to growth factor stimulus GO:0071363 197 0.141
single fertilization GO:0007338 82 0.141
nephron epithelium morphogenesis GO:0072088 68 0.140
gonad development GO:0008406 141 0.140
response to hypoxia GO:0001666 58 0.140
Human
oxidation reduction process GO:0055114 342 0.139
negative regulation of nervous system development GO:0051961 156 0.139
Mouse
male gamete generation GO:0048232 285 0.138
regulation of organ morphogenesis GO:2000027 144 0.138
skeletal system development GO:0001501 356 0.138
Mouse
kidney development GO:0001822 213 0.138
regulation of nucleocytoplasmic transport GO:0046822 73 0.135
regulation of hormone levels GO:0010817 211 0.134
Human
protein localization to nucleus GO:0034504 121 0.134
regulation of cytokine production GO:0001817 266 0.133
hepaticobiliary system development GO:0061008 67 0.133
endocrine process GO:0050886 39 0.133
Human
spermatogenesis GO:0007283 284 0.132
negative regulation of cell proliferation GO:0008285 296 0.132
pallium development GO:0021543 120 0.132
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.130
embryonic skeletal system development GO:0048706 120 0.129
Mouse
regulation of secretion by cell GO:1903530 249 0.128
Human
sensory perception GO:0007600 245 0.127
regulation of protein kinase activity GO:0045859 232 0.125
Human
membrane organization GO:0061024 245 0.125
regulation of blood pressure GO:0008217 93 0.124
single organism nuclear import GO:1902593 95 0.124
cellular amino acid metabolic process GO:0006520 103 0.123
telencephalon development GO:0021537 186 0.123
Mouse
skeletal system morphogenesis GO:0048705 203 0.122
liver development GO:0001889 66 0.119
positive regulation of secretion by cell GO:1903532 114 0.117
Human
regulation of systemic arterial blood pressure GO:0003073 61 0.117
regulation of protein targeting GO:1903533 61 0.117
developmental growth involved in morphogenesis GO:0060560 138 0.115
positive regulation of protein modification process GO:0031401 299 0.115
Human
nitrogen compound transport GO:0071705 271 0.115
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.113
negative regulation of molecular function GO:0044092 258 0.112
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.111
response to growth factor GO:0070848 198 0.110
embryonic appendage morphogenesis GO:0035113 126 0.110
Mouse
ear development GO:0043583 200 0.110
Mouse
regulation of organelle organization GO:0033043 289 0.108
odontogenesis GO:0042476 78 0.108
Mouse
extracellular structure organization GO:0043062 148 0.108
epithelial cell development GO:0002064 159 0.107
hormone secretion GO:0046879 128 0.107
Human
neuron migration GO:0001764 122 0.106
wound healing GO:0042060 157 0.106
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.106
protein import into nucleus GO:0006606 95 0.104
rhythmic process GO:0048511 174 0.102
appendage morphogenesis GO:0035107 149 0.101
Mouse
macromolecule catabolic process GO:0009057 281 0.099
regulation of cell motility GO:2000145 236 0.099
negative regulation of cell development GO:0010721 169 0.099
Mouse
cellular lipid metabolic process GO:0044255 323 0.099
immune effector process GO:0002252 321 0.099
protein targeting GO:0006605 143 0.098
regulation of hormone secretion GO:0046883 88 0.097
Human
circadian rhythm GO:0007623 114 0.096
paraxial mesodermal cell fate commitment GO:0048343 2 0.096
regulation of membrane potential GO:0042391 192 0.095
morphogenesis of a branching epithelium GO:0061138 193 0.095
organelle fission GO:0048285 170 0.095
peptide transport GO:0015833 133 0.094
midgut development GO:0007494 4 0.094
regulation of protein localization to nucleus GO:1900180 60 0.094
erk1 and erk2 cascade GO:0070371 77 0.093
cardiac chamber morphogenesis GO:0003206 93 0.092
sensory perception of sound GO:0007605 97 0.092
mesonephric tubule development GO:0072164 94 0.091
regulation of bmp signaling pathway GO:0030510 60 0.091
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.091
mesonephric epithelium development GO:0072163 94 0.090
central nervous system neuron differentiation GO:0021953 162 0.090
Mouse
mesoderm morphogenesis GO:0048332 64 0.090
multicellular organismal homeostasis GO:0048871 164 0.090
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.089
nephron development GO:0072006 109 0.089
cation homeostasis GO:0055080 212 0.089
gabaergic neuron differentiation GO:0097154 11 0.088
Mouse
developmental maturation GO:0021700 193 0.088
gastrulation GO:0007369 116 0.087
lymphocyte differentiation GO:0030098 242 0.086
nucleobase containing small molecule metabolic process GO:0055086 352 0.086
coagulation GO:0050817 78 0.086
canonical wnt signaling pathway GO:0060070 130 0.085
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.085
carbohydrate derivative biosynthetic process GO:1901137 183 0.082
lymphocyte mediated immunity GO:0002449 139 0.082
digestive tract development GO:0048565 190 0.082
transmembrane transport GO:0055085 412 0.082
organophosphate biosynthetic process GO:0090407 122 0.081
regulation of transferase activity GO:0051338 263 0.081
Human
positive regulation of kidney development GO:0090184 28 0.081
regulation of hydrolase activity GO:0051336 246 0.081
Human
mitotic cell cycle process GO:1903047 159 0.080
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.079
astrocyte differentiation GO:0048708 43 0.079
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.079
nucleocytoplasmic transport GO:0006913 139 0.079
appendage development GO:0048736 166 0.078
Mouse
mesonephros development GO:0001823 97 0.078
purine containing compound biosynthetic process GO:0072522 70 0.078
ion transmembrane transport GO:0034220 361 0.077
regulation of intracellular transport GO:0032386 159 0.077
development of primary male sexual characteristics GO:0046546 88 0.076
single organism cell adhesion GO:0098602 156 0.076
anion transport GO:0006820 177 0.076
muscle tissue development GO:0060537 308 0.076
branching involved in ureteric bud morphogenesis GO:0001658 56 0.075
kidney epithelium development GO:0072073 121 0.074
monocarboxylic acid metabolic process GO:0032787 191 0.074
regulation of cell cycle GO:0051726 281 0.074
Human
cyclic nucleotide biosynthetic process GO:0009190 44 0.074
heart growth GO:0060419 45 0.073
regulation of protein localization GO:0032880 231 0.073
dna metabolic process GO:0006259 303 0.073
positive regulation of apoptotic signaling pathway GO:2001235 95 0.073
Human
purine nucleotide biosynthetic process GO:0006164 65 0.073
regulation of smooth muscle contraction GO:0006940 22 0.072
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.071
regulation of apoptotic signaling pathway GO:2001233 197 0.071
Human
cation transmembrane transport GO:0098655 266 0.071
positive regulation of programmed cell death GO:0043068 218 0.070
Human
multicellular organism growth GO:0035264 161 0.070
placenta development GO:0001890 140 0.070
mitotic cell cycle GO:0000278 195 0.069
Human
regulation of cellular component biogenesis GO:0044087 181 0.068
engulfment of apoptotic cell GO:0043652 3 0.068
morphogenesis of embryonic epithelium GO:0016331 159 0.067
single organismal cell cell adhesion GO:0016337 131 0.067
carboxylic acid transport GO:0046942 100 0.067
response to oxidative stress GO:0006979 123 0.067
fat cell differentiation GO:0045444 160 0.066
cerebral cortex neuron differentiation GO:0021895 19 0.066
Mouse
paraxial mesodermal cell differentiation GO:0048342 2 0.066
response to radiation GO:0009314 165 0.066
outflow tract morphogenesis GO:0003151 53 0.066
ossification GO:0001503 216 0.065
sulfur compound metabolic process GO:0006790 100 0.064
regulation of tube size GO:0035150 57 0.064
cyclic purine nucleotide metabolic process GO:0052652 43 0.064
blood vessel morphogenesis GO:0048514 285 0.063
positive regulation of cytoplasmic transport GO:1903651 40 0.063
regulation of nucleotide biosynthetic process GO:0030808 34 0.063
head morphogenesis GO:0060323 34 0.063
carbohydrate transport GO:0008643 62 0.062
protein import GO:0017038 101 0.062
cartilage development GO:0051216 140 0.062
adult locomotory behavior GO:0008344 91 0.062
regulation of protein import into nucleus GO:0042306 52 0.061
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.061
positive regulation of cellular amine metabolic process GO:0033240 5 0.060
mitochondrion organization GO:0007005 134 0.060
chondrocyte differentiation GO:0002062 72 0.060
muscle contraction GO:0006936 101 0.060
limb development GO:0060173 166 0.060
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.060
skeletal muscle organ development GO:0060538 163 0.059
mesoderm formation GO:0001707 62 0.059
digestive system development GO:0055123 200 0.059
regulation of protein serine threonine kinase activity GO:0071900 157 0.058
positive regulation of cell division GO:0051781 31 0.058
Human
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.058
negative regulation of hydrolase activity GO:0051346 71 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.058
glial cell differentiation GO:0010001 131 0.058
Mouse
neuron apoptotic process GO:0051402 142 0.057
Mouse
neuron maturation GO:0042551 29 0.056
embryonic epithelial tube formation GO:0001838 130 0.056
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.056
kidney morphogenesis GO:0060993 83 0.056
spinal cord motor neuron differentiation GO:0021522 35 0.055
camp biosynthetic process GO:0006171 31 0.055
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.055
nephron epithelium development GO:0072009 92 0.055
extracellular matrix organization GO:0030198 147 0.055
positive regulation of intracellular transport GO:0032388 70 0.055
ribonucleoside metabolic process GO:0009119 245 0.055
palate development GO:0060021 76 0.054
Mouse
camp metabolic process GO:0046058 40 0.054
regulation of stem cell differentiation GO:2000736 50 0.054
cellular response to cytokine stimulus GO:0071345 189 0.054
Human
homeostasis of number of cells GO:0048872 210 0.054
regulation of camp metabolic process GO:0030814 30 0.053
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.053
organic hydroxy compound biosynthetic process GO:1901617 77 0.053
adult behavior GO:0030534 135 0.053
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.053
striated muscle cell proliferation GO:0014855 39 0.052
cofactor metabolic process GO:0051186 80 0.052
purine ribonucleotide biosynthetic process GO:0009152 59 0.052
nucleoside phosphate biosynthetic process GO:1901293 79 0.051
response to organonitrogen compound GO:0010243 246 0.051
regulation of nucleotide metabolic process GO:0006140 169 0.051
regulation of embryonic development GO:0045995 71 0.050
negative regulation of protein metabolic process GO:0051248 282 0.050
epithelial to mesenchymal transition GO:0001837 47 0.050
cell maturation GO:0048469 127 0.050
regulation of cellular catabolic process GO:0031329 242 0.050
regulation of cysteine type endopeptidase activity GO:2000116 65 0.050
Human
primary prostatic bud elongation GO:0060516 2 0.049
spinal cord motor neuron cell fate specification GO:0021520 13 0.049
cell differentiation involved in embryonic placenta development GO:0060706 26 0.049
regulation of transcription factor import into nucleus GO:0042990 24 0.049
regulation of protein complex assembly GO:0043254 83 0.049
cell activation involved in immune response GO:0002263 126 0.048
leydig cell differentiation GO:0033327 10 0.048
regulation of proteolysis GO:0030162 164 0.048
Human
muscle cell proliferation GO:0033002 52 0.048
regulation of cell adhesion GO:0030155 154 0.048
regulation of vasculature development GO:1901342 88 0.048
bone development GO:0060348 120 0.047
mating GO:0007618 27 0.047
organic acid transport GO:0015849 101 0.047
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.046
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.046
intrinsic apoptotic signaling pathway GO:0097193 132 0.045
Human
ribose phosphate biosynthetic process GO:0046390 59 0.045
regulation of angiogenesis GO:0045765 81 0.045
endodermal cell fate specification GO:0001714 4 0.045
inflammatory response GO:0006954 244 0.045
positive regulation of cell death GO:0010942 224 0.044
Human
axial mesoderm formation GO:0048320 3 0.044
neural tube patterning GO:0021532 43 0.044
cellular response to dna damage stimulus GO:0006974 207 0.044
Human
phenol containing compound metabolic process GO:0018958 60 0.044
inner ear receptor cell differentiation GO:0060113 61 0.043
positive regulation of transferase activity GO:0051347 167 0.043
Human
positive regulation of epithelial cell proliferation GO:0050679 68 0.043
Mouse
histamine induced gastric acid secretion GO:0001697 1 0.043
cellular response to gonadotropin stimulus GO:0071371 4 0.043
regulation of organ growth GO:0046620 61 0.043
wnt signaling pathway GO:0016055 188 0.043
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.043
response to organic cyclic compound GO:0014070 198 0.043
gliogenesis GO:0042063 141 0.043
Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.043
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.043
positive regulation of protein transport GO:0051222 93 0.042
cerebral cortex development GO:0021987 86 0.042
regulation of neuron apoptotic process GO:0043523 122 0.042
Mouse
myeloid cell differentiation GO:0030099 233 0.042
neuron neuron synaptic transmission GO:0007270 69 0.042
metanephric loop of henle development GO:0072236 4 0.042
respiratory system development GO:0060541 190 0.041
amide transport GO:0042886 138 0.041
regulation of reactive oxygen species metabolic process GO:2000377 40 0.041
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.041
cell cycle arrest GO:0007050 37 0.041
Human
glucose transport GO:0015758 56 0.041
renal system process GO:0003014 48 0.041
tissue remodeling GO:0048771 102 0.041
pyramidal neuron migration GO:0021852 1 0.040
carbohydrate metabolic process GO:0005975 230 0.040
regulation of blood vessel size GO:0050880 56 0.040
bone mineralization GO:0030282 54 0.040
protein catabolic process GO:0030163 221 0.040
regulation of purine nucleotide metabolic process GO:1900542 169 0.040
regulation of blood circulation GO:1903522 93 0.040
cell fate commitment GO:0045165 210 0.040
Mouse
endothelium development GO:0003158 45 0.040
negative regulation of protein processing GO:0010955 79 0.040
response to extracellular stimulus GO:0009991 127 0.039
protein processing GO:0016485 163 0.039
Human
positive regulation of lymphocyte activation GO:0051251 140 0.039
branching morphogenesis of an epithelial tube GO:0048754 159 0.039
limbic system development GO:0021761 72 0.039
Mouse
protein maturation GO:0051604 176 0.039
Human
axon guidance GO:0007411 141 0.038
reproductive behavior GO:0019098 32 0.038
renal system development GO:0072001 225 0.038
regulation of cartilage development GO:0061035 44 0.038
regulation of reproductive process GO:2000241 66 0.037
primary neural tube formation GO:0014020 95 0.037
transcription from rna polymerase iii promoter GO:0006383 3 0.037
septum primum development GO:0003284 4 0.037
t cell differentiation in thymus GO:0033077 77 0.037
regulation of defense response GO:0031347 233 0.037
negative regulation of response to wounding GO:1903035 77 0.037
cellular response to lipid GO:0071396 145 0.037
Human
determination of heart left right asymmetry GO:0061371 48 0.037
digestive tract morphogenesis GO:0048546 147 0.036
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.036
chemotaxis GO:0006935 247 0.036
cell migration involved in gastrulation GO:0042074 13 0.036
regulation of muscle contraction GO:0006937 49 0.036
positive regulation of mesonephros development GO:0061213 20 0.036
reactive oxygen species biosynthetic process GO:1903409 8 0.036
cell fate specification GO:0001708 72 0.036
female sex differentiation GO:0046660 84 0.036
neural crest cell differentiation GO:0014033 54 0.036
cellular protein complex assembly GO:0043623 116 0.036
divalent metal ion transport GO:0070838 172 0.036
regulation of astrocyte differentiation GO:0048710 20 0.036
embryonic digit morphogenesis GO:0042733 56 0.036
skeletal muscle cell differentiation GO:0035914 66 0.036
regulation of lymphocyte activation GO:0051249 240 0.035
activation of adenylate cyclase activity GO:0007190 4 0.035
ventral spinal cord development GO:0021517 48 0.035
salivary gland morphogenesis GO:0007435 33 0.035
blood circulation GO:0008015 195 0.035
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.035
positive regulation of protein kinase activity GO:0045860 144 0.035
Human
anion transmembrane transport GO:0098656 71 0.035
regulation of intracellular protein transport GO:0033157 82 0.035
positive regulation of bmp signaling pathway GO:0030513 23 0.035
macromolecule methylation GO:0043414 120 0.035
covalent chromatin modification GO:0016569 163 0.035
body morphogenesis GO:0010171 45 0.035
positive regulation of protein localization to nucleus GO:1900182 30 0.035
negative regulation of cell cycle GO:0045786 123 0.035
Human
negative regulation of neuron apoptotic process GO:0043524 92 0.035
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.035
ribose phosphate metabolic process GO:0019693 291 0.034
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.034
regulation of response to wounding GO:1903034 189 0.034
regulation of secretion GO:0051046 274 0.034
Human
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.034
Mouse
endocrine hormone secretion GO:0060986 15 0.034
Human
anatomical structure homeostasis GO:0060249 145 0.034
cardiac ventricle morphogenesis GO:0003208 50 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
Human
regulation of epithelial cell proliferation GO:0050678 141 0.034
protein kinase b signaling GO:0043491 74 0.034
adaptive immune response GO:0002250 155 0.034
multi organism reproductive behavior GO:0044705 29 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.034
response to cold GO:0009409 19 0.034
cellular response to hormone stimulus GO:0032870 150 0.034
Human
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.034
epidermis development GO:0008544 187 0.034
gastrin induced gastric acid secretion GO:0001698 1 0.034
spinal cord development GO:0021510 81 0.034
lipid biosynthetic process GO:0008610 179 0.034
cell matrix adhesion GO:0007160 68 0.033
ribonucleotide biosynthetic process GO:0009260 59 0.033
regulation of mitotic cell cycle GO:0007346 126 0.033
Human
cytokine mediated signaling pathway GO:0019221 115 0.033
organ growth GO:0035265 117 0.033
smoothened signaling pathway GO:0007224 105 0.033
glomerulus development GO:0032835 40 0.033
glial cell development GO:0021782 54 0.033
forelimb morphogenesis GO:0035136 40 0.033
cardiac septum development GO:0003279 59 0.033
cardiac muscle cell proliferation GO:0060038 31 0.033
neural tube closure GO:0001843 90 0.032
acid secretion GO:0046717 33 0.032
cell proliferation involved in kidney development GO:0072111 14 0.032
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.032
leukocyte homeostasis GO:0001776 79 0.032
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.032
mesodermal cell migration GO:0008078 4 0.032
monosaccharide transport GO:0015749 58 0.031
organelle localization GO:0051640 179 0.031
leukocyte apoptotic process GO:0071887 71 0.031
retina morphogenesis in camera type eye GO:0060042 45 0.031
regulation of endopeptidase activity GO:0052548 89 0.031
Human
segmentation GO:0035282 93 0.031
negative regulation of proteolysis GO:0045861 74 0.031
cellular chemical homeostasis GO:0055082 215 0.031
purine containing compound metabolic process GO:0072521 311 0.031
tube closure GO:0060606 91 0.030
regulation of stem cell proliferation GO:0072091 78 0.030
protein oligomerization GO:0051259 67 0.030
regulation of cardiac muscle tissue growth GO:0055021 26 0.030
eye photoreceptor cell differentiation GO:0001754 41 0.030
regulation of glial cell differentiation GO:0045685 41 0.030
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.030
regulation of morphogenesis of a branching structure GO:0060688 53 0.030
regulation of heart growth GO:0060420 31 0.029
regulation of organ formation GO:0003156 34 0.029
pancreatic a cell fate commitment GO:0003326 2 0.029
hippocampus development GO:0021766 52 0.029
Mouse
regulation of feeding behavior GO:0060259 3 0.029
histone modification GO:0016570 159 0.029
aromatic compound catabolic process GO:0019439 286 0.029
small molecule biosynthetic process GO:0044283 132 0.029
negative regulation of bmp signaling pathway GO:0030514 35 0.029
corticotropin releasing hormone secretion GO:0043396 2 0.029
extrinsic apoptotic signaling pathway GO:0097191 126 0.029
tissue homeostasis GO:0001894 115 0.029
regulation of neuron death GO:1901214 134 0.029
Mouse
cardiac ventricle development GO:0003231 83 0.029
negative regulation of astrocyte differentiation GO:0048712 10 0.029
regulation of mesonephros development GO:0061217 24 0.029
muscle hypertrophy GO:0014896 24 0.029
detection of abiotic stimulus GO:0009582 60 0.028
regulation of cytoplasmic transport GO:1903649 112 0.028
hindbrain development GO:0030902 128 0.028
ventricular septum development GO:0003281 42 0.028
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.028
nuclear division GO:0000280 158 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
blastocyst formation GO:0001825 33 0.028
activation of cysteine type endopeptidase activity GO:0097202 27 0.028
Human
granulosa cell differentiation GO:0060014 1 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
embryonic eye morphogenesis GO:0048048 29 0.028
cellular modified amino acid metabolic process GO:0006575 63 0.028
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.028
carbohydrate homeostasis GO:0033500 128 0.028
lymphocyte activation involved in immune response GO:0002285 93 0.028
cardiac chamber development GO:0003205 108 0.028
b cell mediated immunity GO:0019724 71 0.028

Nkx3-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.127
cancer DOID:162 0 0.097
organ system cancer DOID:0050686 0 0.060
sensory system disease DOID:0050155 0 0.041
disease of anatomical entity DOID:7 0 0.041
eye and adnexa disease DOID:1492 0 0.041
nervous system disease DOID:863 0 0.041
eye disease DOID:5614 0 0.041