Mus musculus

62 known processes

Prl7d1

prolactin family 7, subfamily d, member 1

(Aliases: Plfr,MGC117676,PRP,PLF-RP)

Prl7d1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.991
negative regulation of endothelial cell migration GO:0010596 4 0.977
regulation of microvillus assembly GO:0032534 3 0.975
Mouse
regulation of microvillus organization GO:0032530 3 0.892
Mouse
transforming growth factor beta secretion GO:0038044 1 0.737
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.719
regulation of transforming growth factor beta secretion GO:2001201 1 0.668
sprouting angiogenesis GO:0002040 26 0.322
Mouse
regulation of myoblast differentiation GO:0045661 29 0.297
Mouse
positive regulation of cell migration GO:0030335 109 0.270
Mouse
skeletal muscle fiber development GO:0048741 58 0.220
Mouse
negative regulation of angiogenesis GO:0016525 25 0.195
regulation of skeletal muscle fiber development GO:0048742 36 0.189
Mouse
negative regulation of muscle cell differentiation GO:0051148 33 0.188
Mouse
blood vessel morphogenesis GO:0048514 285 0.183
stem cell proliferation GO:0072089 117 0.180
Mouse
negative regulation of myoblast differentiation GO:0045662 18 0.175
Mouse
positive regulation of endothelial cell migration GO:0010595 12 0.165
Mouse
muscle fiber development GO:0048747 76 0.155
Mouse
myotube differentiation GO:0014902 105 0.147
Mouse
positive regulation of neuroblast proliferation GO:0002052 19 0.137
Mouse
regulation of myotube differentiation GO:0010830 62 0.130
Mouse
regulation of brown fat cell proliferation GO:0070347 1 0.129
regulation of cell projection organization GO:0031344 206 0.117
Mouse
muscle tissue development GO:0060537 308 0.116
Mouse
myotube cell development GO:0014904 60 0.109
Mouse
blood vessel endothelial cell migration GO:0043534 23 0.104
striated muscle tissue development GO:0014706 293 0.102
Mouse
tissue migration GO:0090130 68 0.099
angiogenesis GO:0001525 201 0.096
regulation of stem cell proliferation GO:0072091 78 0.093
Mouse
muscle cell development GO:0055001 133 0.090
Mouse
regulation of vasculature development GO:1901342 88 0.089
negative regulation of blood vessel morphogenesis GO:2000181 25 0.085
positive regulation of angiogenesis GO:0045766 46 0.085
Mouse
oxidation reduction process GO:0055114 342 0.084
positive regulation of cell motility GO:2000147 116 0.082
Mouse
ameboidal type cell migration GO:0001667 128 0.079
response to organonitrogen compound GO:0010243 246 0.078
neural precursor cell proliferation GO:0061351 121 0.074
Mouse
positive regulation of cell projection organization GO:0031346 95 0.073
Mouse
regulation of angiogenesis GO:0045765 81 0.073
regulation of cell projection assembly GO:0060491 38 0.071
Mouse
negative regulation of epithelial cell migration GO:0010633 9 0.068
negative regulation of cell motility GO:2000146 61 0.062
cellular amine metabolic process GO:0044106 44 0.061
striated muscle cell development GO:0055002 125 0.060
Mouse
skeletal muscle organ development GO:0060538 163 0.059
Mouse
muscle cell differentiation GO:0042692 261 0.058
Mouse
regulation of endothelial cell migration GO:0010594 22 0.057
endothelial cell migration GO:0043542 44 0.056
regulation of cell motility GO:2000145 236 0.055
myoblast differentiation GO:0045445 52 0.054
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.054
epithelial cell migration GO:0010631 63 0.054
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.053
positive regulation of stem cell proliferation GO:2000648 59 0.052
Mouse
defense response to bacterium GO:0042742 119 0.050
defense response to other organism GO:0098542 197 0.050
transmembrane transport GO:0055085 412 0.050
regulation of muscle tissue development GO:1901861 97 0.049
Mouse
regulation of blood vessel endothelial cell migration GO:0043535 12 0.047
regulation of cell migration GO:0030334 219 0.047
regulation of epithelial cell migration GO:0010632 35 0.046
regulation of homeostatic process GO:0032844 182 0.046
regulation of neuroblast proliferation GO:1902692 27 0.046
Mouse
carbohydrate metabolic process GO:0005975 230 0.045
regulation of interleukin 10 secretion GO:2001179 4 0.045
negative regulation of vasculature development GO:1901343 26 0.043
macromolecule catabolic process GO:0009057 281 0.042
response to organic cyclic compound GO:0014070 198 0.042
positive regulation of epithelial cell migration GO:0010634 19 0.042
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.041
Mouse
response to nutrient levels GO:0031667 109 0.040
positive regulation of nervous system development GO:0051962 221 0.040
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.039
regulation of cellular component biogenesis GO:0044087 181 0.038
Mouse
diacylglycerol biosynthetic process GO:0006651 2 0.038
negative regulation of cell migration GO:0030336 59 0.038
disruption of cells of other organism GO:0044364 13 0.038
protein catabolic process GO:0030163 221 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
epithelium migration GO:0090132 63 0.035
homeostasis of number of cells GO:0048872 210 0.034
male gamete generation GO:0048232 285 0.034
regulation of membrane potential GO:0042391 192 0.034
defense response to gram positive bacterium GO:0050830 50 0.034
blood circulation GO:0008015 195 0.033
cellular response to cytokine stimulus GO:0071345 189 0.033
regulation of angiotensin levels in blood GO:0002002 4 0.033
positive regulation of cytokine production GO:0001819 174 0.032
neuroblast proliferation GO:0007405 49 0.032
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.032
positive regulation of blood vessel endothelial cell migration GO:0043536 5 0.032
Mouse
regulation of cytokine production GO:0001817 266 0.031
aromatic compound catabolic process GO:0019439 286 0.031
nitrogen compound transport GO:0071705 271 0.030
cellular ketone metabolic process GO:0042180 84 0.030
isoprenoid metabolic process GO:0006720 29 0.030
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.030
regulation of angiotensin metabolic process GO:0060177 4 0.030
positive regulation of cell development GO:0010720 237 0.029
Mouse
cytokine production GO:0001816 319 0.029
regulation of feeding behavior GO:0060259 3 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
positive regulation of defense response GO:0031349 124 0.028
spermatogenesis GO:0007283 284 0.028
response to extracellular stimulus GO:0009991 127 0.027
cellular response to organic cyclic compound GO:0071407 87 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of coagulation GO:0050818 31 0.026
ion transmembrane transport GO:0034220 361 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
immune effector process GO:0002252 321 0.026
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.026
response to steroid hormone GO:0048545 56 0.025
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
organophosphate biosynthetic process GO:0090407 122 0.024
terpenoid metabolic process GO:0006721 25 0.024
myeloid leukocyte mediated immunity GO:0002444 42 0.023
coagulation GO:0050817 78 0.023
cell adhesion GO:0007155 329 0.023
purine nucleotide metabolic process GO:0006163 302 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
palate development GO:0060021 76 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
apoptotic signaling pathway GO:0097190 306 0.022
cellular response to lipid GO:0071396 145 0.022
glucose metabolic process GO:0006006 92 0.022
interleukin 10 secretion GO:0072608 4 0.021
regulation of neuron differentiation GO:0045664 281 0.021
regulation of phospholipase c activity GO:1900274 3 0.021
response to drug GO:0042493 75 0.021
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.021
regulation of protein localization GO:0032880 231 0.021
regulation of epithelial cell proliferation GO:0050678 141 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
circadian rhythm GO:0007623 114 0.020
cellular chemical homeostasis GO:0055082 215 0.020
amine metabolic process GO:0009308 45 0.020
fat cell differentiation GO:0045444 160 0.020
interspecies interaction between organisms GO:0044419 83 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
sodium ion transmembrane transport GO:0035725 49 0.020
regulation of phospholipid biosynthetic process GO:0071071 3 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
protein ubiquitination GO:0016567 171 0.019
leukocyte mediated immunity GO:0002443 174 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
multicellular organismal response to stress GO:0033555 62 0.019
cellular homeostasis GO:0019725 240 0.019
small molecule biosynthetic process GO:0044283 132 0.019
regulation of blood pressure GO:0008217 93 0.019
rhythmic process GO:0048511 174 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
disruption by host of symbiont cells GO:0051852 11 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
killing by host of symbiont cells GO:0051873 11 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
ribonucleotide biosynthetic process GO:0009260 59 0.018
actin cytoskeleton organization GO:0030036 220 0.018
positive regulation of neural precursor cell proliferation GO:2000179 42 0.018
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.017
Mouse
negative regulation of cell cycle GO:0045786 123 0.017
regulation of hormone levels GO:0010817 211 0.017
regulation of multi organism process GO:0043900 111 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
response to insulin GO:0032868 100 0.017
organic hydroxy compound biosynthetic process GO:1901617 77 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
placenta development GO:0001890 140 0.017
cell cell adhesion GO:0098609 41 0.017
multi multicellular organism process GO:0044706 109 0.017
dephosphorylation GO:0016311 129 0.016
cellular response to steroid hormone stimulus GO:0071383 33 0.016
retinoid metabolic process GO:0001523 24 0.016
brown fat cell proliferation GO:0070342 1 0.016
conditioned taste aversion GO:0001661 4 0.016
regulation of protein oligomerization GO:0032459 4 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
nucleotide biosynthetic process GO:0009165 78 0.016
response to acid chemical GO:0001101 111 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
phospholipid metabolic process GO:0006644 87 0.016
lipid biosynthetic process GO:0008610 179 0.016
mitral valve development GO:0003174 4 0.016
purine containing compound metabolic process GO:0072521 311 0.016
monosaccharide metabolic process GO:0005996 106 0.016
androgen biosynthetic process GO:0006702 4 0.016
regulation of ossification GO:0030278 112 0.016
camera type eye development GO:0043010 266 0.016
response to peptide GO:1901652 136 0.016
muscle system process GO:0003012 141 0.016
glycerolipid metabolic process GO:0046486 122 0.015
negative regulation of macrophage apoptotic process GO:2000110 3 0.015
cyclic purine nucleotide metabolic process GO:0052652 43 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
regulation of hydrolase activity GO:0051336 246 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
regulation of transferase activity GO:0051338 263 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
purine ribonucleotide biosynthetic process GO:0009152 59 0.015
blood coagulation GO:0007596 76 0.015
negative regulation of defense response GO:0031348 77 0.015
germ cell development GO:0007281 185 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
activation of mapk activity involved in innate immune response GO:0035419 2 0.015
leukocyte differentiation GO:0002521 342 0.014
ribose phosphate biosynthetic process GO:0046390 59 0.014
gland development GO:0048732 330 0.014
cell growth GO:0016049 130 0.014
response to inorganic substance GO:0010035 96 0.014
cellular response to acid chemical GO:0071229 68 0.014
epithelial cell morphogenesis GO:0003382 41 0.014
activation of phospholipase c activity GO:0007202 2 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
negative regulation of blood pressure GO:0045776 22 0.014
cell type specific apoptotic process GO:0097285 268 0.014
positive regulation of response to wounding GO:1903036 66 0.014
anatomical structure homeostasis GO:0060249 145 0.014
response to starvation GO:0042594 65 0.014
purine containing compound biosynthetic process GO:0072522 70 0.014
regulation of protein maturation GO:1903317 96 0.014
mitotic cell cycle GO:0000278 195 0.014
action potential GO:0001508 78 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
sensory perception GO:0007600 245 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.013
regulation of cell adhesion GO:0030155 154 0.013
regulation of hemostasis GO:1900046 28 0.013
macromolecule methylation GO:0043414 120 0.013
regulation of protein catabolic process GO:0042176 108 0.013
mapk cascade GO:0000165 281 0.013
positive regulation of keratinocyte proliferation GO:0010838 4 0.013
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.013
lymphocyte proliferation GO:0046651 164 0.013
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.013
positive regulation of protein oligomerization GO:0032461 4 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
tendon formation GO:0035992 4 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
hexose metabolic process GO:0019318 98 0.013
regulation of innate immune response GO:0045088 91 0.013
bone development GO:0060348 120 0.013
eosinophil migration GO:0072677 3 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.013
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.013
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
protein localization to organelle GO:0033365 185 0.012
peptide transport GO:0015833 133 0.012
regulation of blood coagulation GO:0030193 28 0.012
transmission of nerve impulse GO:0019226 76 0.012
regulation of wound healing GO:0061041 40 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
trophoblast giant cell differentiation GO:0060707 15 0.012
compound eye development GO:0048749 1 0.012
leukocyte mediated cytotoxicity GO:0001909 62 0.012
energy reserve metabolic process GO:0006112 39 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
heterocycle catabolic process GO:0046700 280 0.012
positive regulation of phospholipase activity GO:0010518 3 0.012
growth involved in symbiotic interaction GO:0044110 23 0.012
cyclic nucleotide biosynthetic process GO:0009190 44 0.012
hemostasis GO:0007599 78 0.012
response to lipopolysaccharide GO:0032496 128 0.012
negative regulation of transferase activity GO:0051348 85 0.012
negative regulation of epithelial cell proliferation GO:0050680 64 0.012
covalent chromatin modification GO:0016569 163 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
cell differentiation involved in embryonic placenta development GO:0060706 26 0.012
cellular response to external stimulus GO:0071496 88 0.012
regulation of auditory receptor cell differentiation GO:0045607 4 0.012
negative regulation of multi organism process GO:0043901 68 0.012
multicellular organism growth GO:0035264 161 0.012
peptidyl amino acid modification GO:0018193 336 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
leukocyte homeostasis GO:0001776 79 0.011
sa node cell action potential GO:0086015 4 0.011
myeloid cell differentiation GO:0030099 233 0.011
chromatin organization GO:0006325 206 0.011
maintenance of location GO:0051235 89 0.011
t cell differentiation GO:0030217 174 0.011
regulation of proteolysis GO:0030162 164 0.011
negative regulation of molecular function GO:0044092 258 0.011
negative regulation of proteolysis GO:0045861 74 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
neutrophil mediated killing of symbiont cell GO:0070943 8 0.011
regulation of response to drug GO:2001023 2 0.011
spermatid differentiation GO:0048515 115 0.011
methylation GO:0032259 134 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
positive regulation of epithelial cell proliferation GO:0050679 68 0.011
response to growth factor GO:0070848 198 0.011
sodium ion transport GO:0006814 73 0.011
regulation of defense response GO:0031347 233 0.011
cardiac cell development GO:0055006 41 0.011
circulatory system process GO:0003013 197 0.011
adaptive immune response GO:0002250 155 0.011
tissue homeostasis GO:0001894 115 0.010
neutrophil mediated cytotoxicity GO:0070942 8 0.010
innate immune response GO:0045087 157 0.010
anion transport GO:0006820 177 0.010
cellular protein catabolic process GO:0044257 155 0.010
cellular glucose homeostasis GO:0001678 52 0.010
nuclear division GO:0000280 158 0.010
positive regulation of thymocyte migration GO:2000412 2 0.010
regulation of cell cycle GO:0051726 281 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
neuron neuron synaptic transmission GO:0007270 69 0.010
astrocyte fate commitment GO:0060018 4 0.010
growth of symbiont involved in interaction with host GO:0044116 23 0.010
bone morphogenesis GO:0060349 78 0.010
leukocyte migration GO:0050900 124 0.010
response to monosaccharide GO:0034284 67 0.010
associative learning GO:0008306 61 0.010
neutrophil mediated immunity GO:0002446 19 0.010

Prl7d1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.031
disease of anatomical entity DOID:7 0 0.031
disease of metabolism DOID:0014667 0 0.011
vascular disease DOID:178 0 0.011
eye disease DOID:5614 0 0.011
eye and adnexa disease DOID:1492 0 0.011
nervous system disease DOID:863 0 0.011
sensory system disease DOID:0050155 0 0.011
retinal degeneration DOID:8466 0 0.011
retinal disease DOID:5679 0 0.011
musculoskeletal system disease DOID:17 0 0.010