Mus musculus

174 known processes

Runx3

runt related transcription factor 3

(Aliases: Pebp2a3,Cbfa3,AML2)

Runx3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leukocyte differentiation GO:0002521 342 0.711
Mouse
axon guidance GO:0007411 141 0.459
chemotaxis GO:0006935 247 0.452
axonogenesis GO:0007409 274 0.449
epithelial cell proliferation GO:0050673 174 0.430
regulation of cellular amine metabolic process GO:0033238 20 0.423
cytokine production GO:0001816 319 0.414
amine metabolic process GO:0009308 45 0.411
myeloid cell differentiation GO:0030099 233 0.364
lymphocyte differentiation GO:0030098 242 0.362
Mouse
immune effector process GO:0002252 321 0.337
regulation of leukocyte differentiation GO:1902105 159 0.329
cellular amine metabolic process GO:0044106 44 0.322
skeletal system morphogenesis GO:0048705 203 0.314
Zebrafish Mouse
cellular amino acid metabolic process GO:0006520 103 0.314
gland development GO:0048732 330 0.292
Mouse
regulation of organ morphogenesis GO:2000027 144 0.287
Mouse
developmental maturation GO:0021700 193 0.284
regionalization GO:0003002 337 0.281
dna metabolic process GO:0006259 303 0.258
angiogenesis GO:0001525 201 0.246
Mouse
regulation of lymphocyte activation GO:0051249 240 0.243
regulation of cellular amino acid metabolic process GO:0006521 5 0.240
regulation of cellular ketone metabolic process GO:0010565 66 0.239
odontogenesis of dentin containing tooth GO:0042475 66 0.236
Mouse
t cell activation GO:0042110 289 0.225
Mouse
leukocyte migration GO:0050900 124 0.218
heart morphogenesis GO:0003007 178 0.212
peptidyl amino acid modification GO:0018193 336 0.212
t cell proliferation GO:0042098 120 0.210
myeloid leukocyte differentiation GO:0002573 119 0.209
cellular ketone metabolic process GO:0042180 84 0.202
embryonic organ morphogenesis GO:0048562 276 0.201
Zebrafish Mouse
regulation of cytokine production GO:0001817 266 0.200
cardiac muscle tissue development GO:0048738 130 0.189
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.185
camera type eye development GO:0043010 266 0.182
cell adhesion GO:0007155 329 0.179
odontogenesis GO:0042476 78 0.178
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.177
muscle cell differentiation GO:0042692 261 0.177
embryonic placenta development GO:0001892 98 0.173
response to molecule of bacterial origin GO:0002237 143 0.170
negative regulation of immune system process GO:0002683 209 0.166
lymphocyte proliferation GO:0046651 164 0.166
embryonic skeletal system morphogenesis GO:0048704 91 0.166
Zebrafish Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.164
single organismal cell cell adhesion GO:0016337 131 0.162
positive regulation of cell adhesion GO:0045785 80 0.156
placenta development GO:0001890 140 0.156
regulation of b cell activation GO:0050864 81 0.154
production of molecular mediator of immune response GO:0002440 103 0.154
regulation of leukocyte proliferation GO:0070663 121 0.153
renal system development GO:0072001 225 0.147
ras protein signal transduction GO:0007265 77 0.145
leukocyte activation involved in immune response GO:0002366 126 0.142
leukocyte mediated immunity GO:0002443 174 0.142
cerebral cortex development GO:0021987 86 0.141
positive regulation of epithelial cell proliferation GO:0050679 68 0.136
regulation of cell activation GO:0050865 289 0.136
cardiocyte differentiation GO:0035051 87 0.136
kidney development GO:0001822 213 0.136
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.135
Mouse
regulation of protein kinase activity GO:0045859 232 0.133
digestive tract development GO:0048565 190 0.132
regulation of t cell proliferation GO:0042129 92 0.130
leukocyte proliferation GO:0070661 172 0.129
negative regulation of apoptotic signaling pathway GO:2001234 104 0.128
apoptotic signaling pathway GO:0097190 306 0.128
positive regulation of lymphocyte activation GO:0051251 140 0.127
small gtpase mediated signal transduction GO:0007264 97 0.125
nucleoside phosphate catabolic process GO:1901292 222 0.123
cardiac chamber morphogenesis GO:0003206 93 0.123
neuron projection guidance GO:0097485 141 0.123
b cell activation GO:0042113 161 0.122
cation transport GO:0006812 399 0.122
positive regulation of cell activation GO:0050867 158 0.120
skeletal muscle organ development GO:0060538 163 0.119
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.118
positive regulation of transferase activity GO:0051347 167 0.117
mapk cascade GO:0000165 281 0.117
spinal cord development GO:0021510 81 0.116
sensory organ morphogenesis GO:0090596 242 0.114
negative regulation of cell proliferation GO:0008285 296 0.112
action potential GO:0001508 78 0.112
t cell differentiation GO:0030217 174 0.112
Mouse
positive regulation of kinase activity GO:0033674 155 0.110
cellular response to acid chemical GO:0071229 68 0.109
olfactory lobe development GO:0021988 32 0.108
regulation of neuron projection development GO:0010975 169 0.107
negative regulation of lymphocyte activation GO:0051250 91 0.105
regulation of transferase activity GO:0051338 263 0.103
forebrain development GO:0030900 302 0.102
regulation of defense response GO:0031347 233 0.102
digestive tract morphogenesis GO:0048546 147 0.102
epithelial tube morphogenesis GO:0060562 303 0.101
face morphogenesis GO:0060325 29 0.101
positive regulation of cellular amine metabolic process GO:0033240 5 0.099
rho protein signal transduction GO:0007266 32 0.099
bmp signaling pathway GO:0030509 93 0.099
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.097
regulation of protein localization GO:0032880 231 0.096
digestive system development GO:0055123 200 0.096
mitotic cell cycle GO:0000278 195 0.095
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.095
negative regulation of cytokine production GO:0001818 84 0.095
regulation of osteoclast differentiation GO:0045670 36 0.094
extrinsic apoptotic signaling pathway GO:0097191 126 0.094
inflammatory response GO:0006954 244 0.093
regulation of cell cycle process GO:0010564 160 0.093
positive regulation of protein modification process GO:0031401 299 0.093
cell type specific apoptotic process GO:0097285 268 0.092
regulation of kinase activity GO:0043549 249 0.092
circulatory system process GO:0003013 197 0.091
regulation of myeloid cell differentiation GO:0045637 96 0.091
respiratory tube development GO:0030323 167 0.090
regulation of lymphocyte differentiation GO:0045619 107 0.090
regulation of reactive oxygen species metabolic process GO:2000377 40 0.090
lymphocyte activation involved in immune response GO:0002285 93 0.090
somatic cell dna recombination GO:0016444 51 0.089
immunoglobulin production GO:0002377 73 0.088
gliogenesis GO:0042063 141 0.088
positive regulation of leukocyte differentiation GO:1902107 86 0.084
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.084
negative regulation of cell cycle GO:0045786 123 0.084
regulation of t cell activation GO:0050863 170 0.084
limb morphogenesis GO:0035108 149 0.083
Mouse
wnt signaling pathway GO:0016055 188 0.082
limb development GO:0060173 166 0.082
Mouse
response to lipopolysaccharide GO:0032496 128 0.082
positive regulation of immune effector process GO:0002699 107 0.081
positive regulation of protein kinase activity GO:0045860 144 0.080
purine nucleoside metabolic process GO:0042278 241 0.080
embryonic appendage morphogenesis GO:0035113 126 0.079
Mouse
regulation of neuron differentiation GO:0045664 281 0.079
negative regulation of t cell activation GO:0050868 65 0.079
cation transmembrane transport GO:0098655 266 0.079
mitotic cell cycle process GO:1903047 159 0.078
bone morphogenesis GO:0060349 78 0.078
Mouse
regulation of anatomical structure size GO:0090066 178 0.078
central nervous system neuron differentiation GO:0021953 162 0.078
anion transport GO:0006820 177 0.077
asymmetric neuroblast division GO:0055059 1 0.077
negative regulation of nervous system development GO:0051961 156 0.077
regulation of establishment of protein localization GO:0070201 181 0.077
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.076
hindbrain development GO:0030902 128 0.075
mesenchymal cell development GO:0014031 93 0.075
cellular response to lipid GO:0071396 145 0.075
b cell activation involved in immune response GO:0002312 50 0.074
cardiac muscle cell differentiation GO:0055007 69 0.073
regulation of cell adhesion GO:0030155 154 0.073
regulation of lymphocyte proliferation GO:0050670 117 0.073
organonitrogen compound catabolic process GO:1901565 264 0.073
homeostasis of number of cells GO:0048872 210 0.073
cell activation involved in immune response GO:0002263 126 0.071
ear development GO:0043583 200 0.071
ribonucleotide catabolic process GO:0009261 208 0.071
positive regulation of mapk cascade GO:0043410 170 0.071
regulation of cytokine secretion GO:0050707 61 0.071
carbohydrate derivative catabolic process GO:1901136 231 0.070
olfactory bulb development GO:0021772 30 0.070
regulation of mapk cascade GO:0043408 248 0.070
purine containing compound catabolic process GO:0072523 213 0.069
regulation of cellular component biogenesis GO:0044087 181 0.069
lymphocyte mediated immunity GO:0002449 139 0.068
immune response regulating signaling pathway GO:0002764 125 0.068
embryonic limb morphogenesis GO:0030326 126 0.068
Mouse
skin development GO:0043588 220 0.068
forelimb morphogenesis GO:0035136 40 0.068
Mouse
response to growth factor GO:0070848 198 0.068
Mouse
cellular protein complex assembly GO:0043623 116 0.067
cardiac chamber development GO:0003205 108 0.066
epithelial to mesenchymal transition GO:0001837 47 0.066
microtubule based process GO:0007017 236 0.065
neuron apoptotic process GO:0051402 142 0.065
respiratory system development GO:0060541 190 0.065
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.065
alpha beta t cell activation GO:0046631 91 0.064
mammary gland duct morphogenesis GO:0060603 38 0.064
somatic diversification of immune receptors GO:0002200 53 0.064
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.064
cellular nitrogen compound catabolic process GO:0044270 280 0.064
positive regulation of b cell activation GO:0050871 49 0.063
negative regulation of phosphorylation GO:0042326 166 0.063
regulation of mitotic cell cycle GO:0007346 126 0.063
regulation of myeloid leukocyte differentiation GO:0002761 58 0.063
aromatic compound catabolic process GO:0019439 286 0.063
negative regulation of cellular protein metabolic process GO:0032269 247 0.063
neuromuscular process GO:0050905 99 0.062
tissue remodeling GO:0048771 102 0.062
embryonic skeletal system development GO:0048706 120 0.062
Zebrafish Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.062
palate development GO:0060021 76 0.061
positive regulation of apoptotic process GO:0043065 217 0.061
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.061
negative regulation of leukocyte proliferation GO:0070664 46 0.061
innate immune response GO:0045087 157 0.060
cognition GO:0050890 149 0.060
pallium development GO:0021543 120 0.060
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
regulation of cytoskeleton organization GO:0051493 122 0.059
stem cell proliferation GO:0072089 117 0.059
regulation of vesicle mediated transport GO:0060627 139 0.059
anatomical structure homeostasis GO:0060249 145 0.059
extracellular structure organization GO:0043062 148 0.059
spermatid development GO:0007286 108 0.059
regulation of stem cell proliferation GO:0072091 78 0.059
positive regulation of protein transport GO:0051222 93 0.059
purine nucleotide catabolic process GO:0006195 211 0.058
reactive oxygen species metabolic process GO:0072593 84 0.058
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.058
morphogenesis of a branching structure GO:0001763 203 0.058
organic hydroxy compound metabolic process GO:1901615 203 0.058
ribonucleoside catabolic process GO:0042454 206 0.057
sensory perception GO:0007600 245 0.057
negative regulation of growth GO:0045926 99 0.057
activation of innate immune response GO:0002218 56 0.057
mammary gland epithelium development GO:0061180 65 0.057
muscle tissue development GO:0060537 308 0.056
positive regulation of lymphocyte proliferation GO:0050671 70 0.056
positive regulation of cytokine production GO:0001819 174 0.056
cytokine secretion GO:0050663 72 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.056
heart growth GO:0060419 45 0.056
telencephalon development GO:0021537 186 0.056
regulation of cellular response to stress GO:0080135 159 0.055
macromolecule catabolic process GO:0009057 281 0.055
adaptive immune response GO:0002250 155 0.054
endocrine system development GO:0035270 98 0.054
ensheathment of neurons GO:0007272 76 0.054
smad protein complex assembly GO:0007183 1 0.054
regulation of cell cycle GO:0051726 281 0.054
cellular lipid metabolic process GO:0044255 323 0.054
nucleoside triphosphate metabolic process GO:0009141 230 0.053
somatic diversification of immunoglobulins GO:0016445 43 0.053
glycosyl compound metabolic process GO:1901657 246 0.053
endodermal cell fate specification GO:0001714 4 0.053
nucleoside metabolic process GO:0009116 246 0.052
posttranscriptional regulation of gene expression GO:0010608 155 0.051
dna recombination GO:0006310 92 0.051
regulation of membrane potential GO:0042391 192 0.051
regulation of b cell proliferation GO:0030888 39 0.051
male gamete generation GO:0048232 285 0.050
negative regulation of protein metabolic process GO:0051248 282 0.050
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.050
cell maturation GO:0048469 127 0.049
organic anion transport GO:0015711 137 0.049
regulation of protein transport GO:0051223 163 0.049
blood vessel morphogenesis GO:0048514 285 0.049
Mouse
establishment of protein localization to organelle GO:0072594 118 0.049
morphogenesis of a branching epithelium GO:0061138 193 0.049
positive regulation of osteoclast differentiation GO:0045672 15 0.048
transmission of nerve impulse GO:0019226 76 0.048
regulation of leukocyte mediated immunity GO:0002703 104 0.048
striated muscle tissue development GO:0014706 293 0.048
stem cell differentiation GO:0048863 268 0.047
Mouse
asymmetric stem cell division GO:0098722 3 0.047
urogenital system development GO:0001655 261 0.047
extracellular matrix organization GO:0030198 147 0.047
positive regulation of leukocyte proliferation GO:0070665 73 0.047
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.047
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.046
cell growth GO:0016049 130 0.046
regulation of intracellular transport GO:0032386 159 0.046
cell fate commitment GO:0045165 210 0.046
Mouse
muscle cell proliferation GO:0033002 52 0.046
striated muscle cell proliferation GO:0014855 39 0.045
muscle system process GO:0003012 141 0.045
regulation of metal ion transport GO:0010959 106 0.045
positive regulation of protein secretion GO:0050714 52 0.045
regulation of cell growth GO:0001558 91 0.045
positive regulation of neuron differentiation GO:0045666 141 0.045
lipid biosynthetic process GO:0008610 179 0.044
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.044
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.044
b cell proliferation GO:0042100 53 0.044
mesodermal cell migration GO:0008078 4 0.044
ribose phosphate metabolic process GO:0019693 291 0.044
ameboidal type cell migration GO:0001667 128 0.044
skeletal muscle cell differentiation GO:0035914 66 0.043
organ growth GO:0035265 117 0.043
positive regulation of b cell proliferation GO:0030890 24 0.043
negative regulation of leukocyte differentiation GO:1902106 51 0.043
tube closure GO:0060606 91 0.043
translation GO:0006412 93 0.043
lung development GO:0030324 164 0.043
bone development GO:0060348 120 0.043
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.043
negative regulation of protein modification process GO:0031400 163 0.043
regulation of immunoglobulin production GO:0002637 42 0.042
protein localization to membrane GO:0072657 108 0.042
epidermis development GO:0008544 187 0.042
isotype switching GO:0045190 36 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
mesoderm formation GO:0001707 62 0.042
neuron migration GO:0001764 122 0.041
cellular response to biotic stimulus GO:0071216 92 0.041
regulation of cellular component size GO:0032535 121 0.041
purine containing compound metabolic process GO:0072521 311 0.041
single organism cell adhesion GO:0098602 156 0.041
endocytosis GO:0006897 168 0.041
protein catabolic process GO:0030163 221 0.041
osteoclast differentiation GO:0030316 62 0.041
regulation of cellular catabolic process GO:0031329 242 0.041
metanephros development GO:0001656 79 0.040
spermatogenesis GO:0007283 284 0.040
guanosine containing compound metabolic process GO:1901068 144 0.040
learning or memory GO:0007611 148 0.040
regulation of adaptive immune response GO:0002819 90 0.040
positive regulation of cell migration GO:0030335 109 0.040
regulation of ras protein signal transduction GO:0046578 114 0.040
liver development GO:0001889 66 0.039
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.039
regulation of production of molecular mediator of immune response GO:0002700 65 0.039
multicellular organismal signaling GO:0035637 91 0.039
reactive nitrogen species metabolic process GO:2001057 0 0.039
positive regulation of nucleotide metabolic process GO:0045981 114 0.039
response to fibroblast growth factor GO:0071774 47 0.039
Mouse
regulation of cell migration GO:0030334 219 0.039
body morphogenesis GO:0010171 45 0.039
chromatin modification GO:0016568 187 0.039
myotube differentiation GO:0014902 105 0.039
positive regulation of myeloid cell differentiation GO:0045639 43 0.039
olfactory learning GO:0008355 2 0.039
stem cell maintenance GO:0019827 130 0.039
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.039
branching morphogenesis of an epithelial tube GO:0048754 159 0.039
negative regulation of cellular amine metabolic process GO:0033239 1 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
regulation of secretion by cell GO:1903530 249 0.039
neuronal action potential GO:0019228 54 0.039
inositol lipid mediated signaling GO:0048017 41 0.039
regulation of ion transport GO:0043269 215 0.039
alpha beta t cell differentiation GO:0046632 69 0.039
blood circulation GO:0008015 195 0.039
granulocyte migration GO:0097530 43 0.038
regulation of rho gtpase activity GO:0032319 58 0.038
chromatin organization GO:0006325 206 0.038
positive regulation of gtp catabolic process GO:0033126 85 0.038
organelle assembly GO:0070925 177 0.038
forebrain generation of neurons GO:0021872 63 0.038
cellular component assembly involved in morphogenesis GO:0010927 139 0.038
immune response activating signal transduction GO:0002757 116 0.038
tube formation GO:0035148 140 0.038
locomotory behavior GO:0007626 195 0.037
carboxylic acid transport GO:0046942 100 0.037
multi multicellular organism process GO:0044706 109 0.037
regulation of homeostatic process GO:0032844 182 0.037
oxidation reduction process GO:0055114 342 0.037
histone modification GO:0016570 159 0.037
positive regulation of t cell activation GO:0050870 101 0.037
hepaticobiliary system development GO:0061008 67 0.037
Mouse
regulation of cell motility GO:2000145 236 0.037
nucleotide metabolic process GO:0009117 332 0.037
carbohydrate metabolic process GO:0005975 230 0.037
regulation of lymphocyte mediated immunity GO:0002706 84 0.036
organelle fission GO:0048285 170 0.036
response to organonitrogen compound GO:0010243 246 0.036
muscle contraction GO:0006936 101 0.036
negative regulation of defense response GO:0031348 77 0.036
ribonucleoside triphosphate metabolic process GO:0009199 220 0.036
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
cell fate specification GO:0001708 72 0.036
cell division GO:0051301 120 0.036
negative regulation of cell activation GO:0050866 111 0.036
epithelial tube formation GO:0072175 130 0.036
positive regulation of cell death GO:0010942 224 0.036
positive regulation of t cell proliferation GO:0042102 52 0.035
positive regulation of cell motility GO:2000147 116 0.035
regulation of cell projection organization GO:0031344 206 0.035
gonad development GO:0008406 141 0.035
regulation of osteoblast differentiation GO:0045667 67 0.035
Mouse
exocrine system development GO:0035272 45 0.035
ear morphogenesis GO:0042471 118 0.035
head morphogenesis GO:0060323 34 0.035
tissue homeostasis GO:0001894 115 0.034
monocyte differentiation GO:0030224 9 0.034
membrane organization GO:0061024 245 0.034
regulation of wnt signaling pathway GO:0030111 123 0.034
phospholipid metabolic process GO:0006644 87 0.034
regulation of hydrolase activity GO:0051336 246 0.034
cellular response to growth factor stimulus GO:0071363 197 0.034
Mouse
ribonucleoside metabolic process GO:0009119 245 0.034
response to retinoic acid GO:0032526 56 0.034
Mouse
lateral line system development GO:0048925 1 0.034
toll like receptor signaling pathway GO:0002224 38 0.034
maintenance of location GO:0051235 89 0.033
nitrogen compound transport GO:0071705 271 0.033
leukocyte homeostasis GO:0001776 79 0.033
cellular response to peptide GO:1901653 92 0.033
protein targeting GO:0006605 143 0.033
positive regulation of cellular catabolic process GO:0031331 148 0.033
regulation of cell size GO:0008361 72 0.033
cell differentiation in spinal cord GO:0021515 53 0.033
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.033
calcium ion transport GO:0006816 159 0.032
sequestering of metal ion GO:0051238 19 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
kidney morphogenesis GO:0060993 83 0.032
negative regulation of cell cycle process GO:0010948 69 0.032
neuron death GO:0070997 154 0.032
ion transmembrane transport GO:0034220 361 0.032
protein acylation GO:0043543 64 0.032
intracellular protein transport GO:0006886 204 0.032
regulation of hormone levels GO:0010817 211 0.032
mammary gland morphogenesis GO:0060443 54 0.032
telencephalon cell migration GO:0022029 55 0.032
regulation of protein complex assembly GO:0043254 83 0.032
myelination GO:0042552 74 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.031
myeloid leukocyte migration GO:0097529 57 0.031
phagocytosis GO:0006909 66 0.031
cellular response to molecule of bacterial origin GO:0071219 83 0.031
multicellular organismal homeostasis GO:0048871 164 0.031
hair follicle development GO:0001942 85 0.031
regulation of cardiac muscle tissue development GO:0055024 31 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
axon ensheathment GO:0008366 76 0.031
regulation of neuron apoptotic process GO:0043523 122 0.031
multicellular organism growth GO:0035264 161 0.031
cell cell junction organization GO:0045216 72 0.031
regulation of cytoplasmic transport GO:1903649 112 0.031
neural tube closure GO:0001843 90 0.031
microglia differentiation GO:0014004 2 0.030
divalent inorganic cation transport GO:0072511 178 0.030
negative regulation of lymphocyte proliferation GO:0050672 45 0.030
intracellular receptor signaling pathway GO:0030522 74 0.030
steroid metabolic process GO:0008202 119 0.030
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.030
germ cell development GO:0007281 185 0.030
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
myeloid leukocyte activation GO:0002274 83 0.030
nucleoside catabolic process GO:0009164 206 0.030
peptidyl tyrosine phosphorylation GO:0018108 143 0.030
innate immune response activating signal transduction GO:0002758 50 0.030
negative regulation of myeloid cell differentiation GO:0045638 38 0.030
regulation of chromosome organization GO:0033044 83 0.030
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.030
negative regulation of t cell proliferation GO:0042130 38 0.030
pericardium development GO:0060039 16 0.030
cardiac muscle tissue morphogenesis GO:0055008 44 0.030
positive regulation of gtpase activity GO:0043547 85 0.030
regulation of b cell mediated immunity GO:0002712 37 0.029
atp metabolic process GO:0046034 75 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
organophosphate catabolic process GO:0046434 232 0.029
positive regulation of map kinase activity GO:0043406 84 0.029
interferon gamma production GO:0032609 67 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
regulation of actin filament based process GO:0032970 99 0.029
morphogenesis of embryonic epithelium GO:0016331 159 0.029
regulation of protein serine threonine kinase activity GO:0071900 157 0.029
formation of primary germ layer GO:0001704 77 0.029
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.029
cell cycle g1 s phase transition GO:0044843 57 0.029
compound eye development GO:0048749 1 0.029
neural tube development GO:0021915 160 0.029
response to transforming growth factor beta GO:0071559 88 0.029
Mouse
activation of immune response GO:0002253 138 0.029
cellular response to cytokine stimulus GO:0071345 189 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
chemokine production GO:0032602 34 0.028
limbic system development GO:0021761 72 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
phosphatidylinositol mediated signaling GO:0048015 41 0.028
regulation of response to wounding GO:1903034 189 0.028
nephron epithelium morphogenesis GO:0072088 68 0.028
negative regulation of phagocytosis GO:0050765 4 0.028
nuclear division GO:0000280 158 0.028
face development GO:0060324 38 0.028
regulation of neural retina development GO:0061074 3 0.028
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.028
connective tissue development GO:0061448 179 0.028
regulation of calcium ion transport into cytosol GO:0010522 31 0.028
regulation of purine nucleotide catabolic process GO:0033121 122 0.028
wound healing GO:0042060 157 0.028
cytoplasmic transport GO:0016482 234 0.027
alcohol metabolic process GO:0006066 116 0.027
modification by symbiont of host morphology or physiology GO:0044003 4 0.027
regulation of dna recombination GO:0000018 34 0.027
interleukin 18 production GO:0032621 4 0.027
norepinephrine secretion GO:0048243 2 0.027
positive regulation of immunoglobulin production GO:0002639 28 0.027
cytokine mediated signaling pathway GO:0019221 115 0.027
negative regulation of cell development GO:0010721 169 0.027
negative regulation of cellular component organization GO:0051129 194 0.027
pharynx development GO:0060465 1 0.027
regulation of neurotransmitter levels GO:0001505 87 0.027
interspecies interaction between organisms GO:0044419 83 0.027
fat cell differentiation GO:0045444 160 0.026
hair cycle GO:0042633 90 0.026

Runx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
musculoskeletal system disease DOID:17 0 0.051
connective tissue disease DOID:65 0 0.051
cancer DOID:162 0 0.045
disease of cellular proliferation DOID:14566 0 0.045
organ system cancer DOID:0050686 0 0.045