Mus musculus

32 known processes

Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

(Aliases: mKIAA0705,Acvrinp1,Acvrip1,S-SCAM,Magi-2,Acvri1)

Magi2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
camera type eye development GO:0043010 266 0.095
cellular amino acid metabolic process GO:0006520 103 0.085
microtubule based process GO:0007017 236 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.078
regulation of cellular amine metabolic process GO:0033238 20 0.070
amine metabolic process GO:0009308 45 0.068
purine nucleotide metabolic process GO:0006163 302 0.068
cellular ketone metabolic process GO:0042180 84 0.068
cellular component assembly involved in morphogenesis GO:0010927 139 0.058
multicellular organismal signaling GO:0035637 91 0.057
regulation of system process GO:0044057 200 0.055
nucleotide metabolic process GO:0009117 332 0.055
nucleoside metabolic process GO:0009116 246 0.055
male gamete generation GO:0048232 285 0.055
spermatogenesis GO:0007283 284 0.053
ribonucleoside metabolic process GO:0009119 245 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
rho protein signal transduction GO:0007266 32 0.050
urogenital system development GO:0001655 261 0.049
Rat
microtubule cytoskeleton organization GO:0000226 157 0.049
regulation of organelle organization GO:0033043 289 0.049
digestive tract morphogenesis GO:0048546 147 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.047
purine nucleoside triphosphate metabolic process GO:0009144 226 0.046
action potential GO:0001508 78 0.045
sensory organ morphogenesis GO:0090596 242 0.044
renal system development GO:0072001 225 0.042
Rat
purine ribonucleotide metabolic process GO:0009150 290 0.042
purine containing compound metabolic process GO:0072521 311 0.042
microtubule based movement GO:0007018 84 0.042
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
nucleoside phosphate catabolic process GO:1901292 222 0.041
synaptic transmission GO:0007268 329 0.041
cation transmembrane transport GO:0098655 266 0.041
regulation of secretion GO:0051046 274 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.039
organonitrogen compound catabolic process GO:1901565 264 0.039
ribose phosphate metabolic process GO:0019693 291 0.039
connective tissue development GO:0061448 179 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
nucleoside catabolic process GO:0009164 206 0.038
heterocycle catabolic process GO:0046700 280 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
regulation of purine nucleotide metabolic process GO:1900542 169 0.037
skeletal system development GO:0001501 356 0.037
regulation of purine nucleotide catabolic process GO:0033121 122 0.036
ion transmembrane transport GO:0034220 361 0.036
regulation of cell cycle GO:0051726 281 0.035
Rat
cellular amine metabolic process GO:0044106 44 0.035
positive regulation of protein modification process GO:0031401 299 0.035
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.034
cellular protein complex assembly GO:0043623 116 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.034
cartilage development GO:0051216 140 0.034
ribonucleotide metabolic process GO:0009259 291 0.034
actin cytoskeleton organization GO:0030036 220 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
positive regulation of cell development GO:0010720 237 0.034
Rat
positive regulation of transferase activity GO:0051347 167 0.033
Mouse
organelle assembly GO:0070925 177 0.033
cell adhesion GO:0007155 329 0.033
regulation of nucleoside metabolic process GO:0009118 130 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
cation transport GO:0006812 399 0.032
inorganic ion transmembrane transport GO:0098660 234 0.032
nitrogen compound transport GO:0071705 271 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
respiratory tube development GO:0030323 167 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
smoothened signaling pathway GO:0007224 105 0.032
muscle cell differentiation GO:0042692 261 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
membrane organization GO:0061024 245 0.031
Rat
nucleotide catabolic process GO:0009166 217 0.031
kidney development GO:0001822 213 0.030
Rat
male genitalia morphogenesis GO:0048808 4 0.030
regulation of transferase activity GO:0051338 263 0.030
Mouse
muscle tissue development GO:0060537 308 0.030
guanosine containing compound metabolic process GO:1901068 144 0.030
transmembrane transport GO:0055085 412 0.030
regulation of protein kinase activity GO:0045859 232 0.030
Mouse
lung development GO:0030324 164 0.030
exocytosis GO:0006887 121 0.030
purine nucleotide catabolic process GO:0006195 211 0.029
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
gtp catabolic process GO:0006184 143 0.029
regulation of hormone levels GO:0010817 211 0.029
cell type specific apoptotic process GO:0097285 268 0.028
ras protein signal transduction GO:0007265 77 0.028
regulation of membrane potential GO:0042391 192 0.028
organelle fission GO:0048285 170 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
regulation of cellular component biogenesis GO:0044087 181 0.027
ossification GO:0001503 216 0.027
purine containing compound catabolic process GO:0072523 213 0.027
neuronal action potential GO:0019228 54 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
cell fate commitment GO:0045165 210 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
development of primary sexual characteristics GO:0045137 143 0.026
digestive system development GO:0055123 200 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
organophosphate catabolic process GO:0046434 232 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
male sex differentiation GO:0046661 109 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
mitotic cell cycle GO:0000278 195 0.025
ear development GO:0043583 200 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
regulation of mitotic cell cycle GO:0007346 126 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.024
striated muscle tissue development GO:0014706 293 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
forebrain development GO:0030900 302 0.023
cilium morphogenesis GO:0060271 102 0.023
actin filament organization GO:0007015 113 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
male anatomical structure morphogenesis GO:0090598 4 0.022
spermatid differentiation GO:0048515 115 0.022
cytoplasmic transport GO:0016482 234 0.022
Rat
cellular response to growth factor stimulus GO:0071363 197 0.022
Rat
regulation of cell motility GO:2000145 236 0.022
Rat
peptidyl amino acid modification GO:0018193 336 0.022
peptide hormone secretion GO:0030072 109 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
amide transport GO:0042886 138 0.022
homeostasis of number of cells GO:0048872 210 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
single organism cell adhesion GO:0098602 156 0.021
regulation of kinase activity GO:0043549 249 0.021
Mouse
cellular homeostasis GO:0019725 240 0.021
aromatic compound catabolic process GO:0019439 286 0.021
developmental maturation GO:0021700 193 0.021
protein polymerization GO:0051258 57 0.021
regulation of secretion by cell GO:1903530 249 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.020
Human
embryonic organ morphogenesis GO:0048562 276 0.020
cognition GO:0050890 149 0.020
Worm
respiratory system development GO:0060541 190 0.020
learning GO:0007612 98 0.020
Worm
positive regulation of neuron differentiation GO:0045666 141 0.020
Rat
wnt signaling pathway GO:0016055 188 0.020
positive regulation of cell cycle GO:0045787 92 0.020
regulation of mapk cascade GO:0043408 248 0.020
Mouse
intracellular protein transport GO:0006886 204 0.020
olfactory learning GO:0008355 2 0.020
digestive tract development GO:0048565 190 0.020
myeloid cell differentiation GO:0030099 233 0.020
nuclear division GO:0000280 158 0.020
organ growth GO:0035265 117 0.020
glycoprotein metabolic process GO:0009100 116 0.020
response to growth factor GO:0070848 198 0.019
Rat
gtp metabolic process GO:0046039 144 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
hormone secretion GO:0046879 128 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
striated muscle cell development GO:0055002 125 0.019
epithelial cell proliferation GO:0050673 174 0.019
gonad development GO:0008406 141 0.019
regulation of gtp catabolic process GO:0033124 113 0.019
morphogenesis of a branching structure GO:0001763 203 0.019
multi multicellular organism process GO:0044706 109 0.019
establishment of glial blood brain barrier GO:0060857 2 0.018
regulation of neuron differentiation GO:0045664 281 0.018
Rat
glycoprotein biosynthetic process GO:0009101 89 0.018
immune effector process GO:0002252 321 0.018
development of primary male sexual characteristics GO:0046546 88 0.018
hindbrain development GO:0030902 128 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
Human
dendrite development GO:0016358 115 0.018
axon guidance GO:0007411 141 0.018
positive regulation of neuron projection development GO:0010976 79 0.018
Rat
positive regulation of protein kinase activity GO:0045860 144 0.018
Mouse
carbohydrate homeostasis GO:0033500 128 0.018
muscle cell development GO:0055001 133 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.018
meiotic cell cycle GO:0051321 122 0.018
myeloid cell homeostasis GO:0002262 114 0.017
cilium assembly GO:0042384 81 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
compound eye development GO:0048749 1 0.017
odontogenesis of dentin containing tooth GO:0042475 66 0.017
peptide secretion GO:0002790 114 0.017
embryonic limb morphogenesis GO:0030326 126 0.017
lateral inhibition GO:0046331 1 0.017
angiogenesis GO:0001525 201 0.017
cellular chemical homeostasis GO:0055082 215 0.017
epidermis development GO:0008544 187 0.017
neural tube development GO:0021915 160 0.017
erythrocyte differentiation GO:0030218 88 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
response to organonitrogen compound GO:0010243 246 0.016
kidney epithelium development GO:0072073 121 0.016
Rat
heart morphogenesis GO:0003007 178 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of hormone secretion GO:0046883 88 0.016
muscle system process GO:0003012 141 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
fat cell differentiation GO:0045444 160 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
telencephalon development GO:0021537 186 0.016
chemotaxis GO:0006935 247 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
endomembrane system organization GO:0010256 147 0.016
b cell activation GO:0042113 161 0.016
spermatid development GO:0007286 108 0.016
positive regulation of osteoblast differentiation GO:0045669 34 0.016
regulation of rho gtpase activity GO:0032319 58 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
skin development GO:0043588 220 0.015
blood circulation GO:0008015 195 0.015
positive regulation of cell adhesion GO:0045785 80 0.015
regulation of homeostatic process GO:0032844 182 0.015
regulation of binding GO:0051098 111 0.015
neural precursor cell proliferation GO:0061351 121 0.015
protein complex disassembly GO:0043241 40 0.015
response to acid chemical GO:0001101 111 0.015
cell maturation GO:0048469 127 0.015
regulation of muscle tissue development GO:1901861 97 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
stem cell differentiation GO:0048863 268 0.015
regulation of cell cycle process GO:0010564 160 0.015
negative regulation of nervous system development GO:0051961 156 0.015
defecation GO:0030421 1 0.015
ensheathment of neurons GO:0007272 76 0.015
retina development in camera type eye GO:0060041 119 0.015
maintenance of location GO:0051235 89 0.015
positive regulation of secretion by cell GO:1903532 114 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
glial cell differentiation GO:0010001 131 0.014
skeletal system morphogenesis GO:0048705 203 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
regulation of cell migration GO:0030334 219 0.014
Rat
negative regulation of protein modification process GO:0031400 163 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
positive regulation of nervous system development GO:0051962 221 0.014
Rat
regulation of vesicle mediated transport GO:0060627 139 0.014
Human
cell growth GO:0016049 130 0.014
mitotic cell cycle process GO:1903047 159 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
locomotory behavior GO:0007626 195 0.014
positive regulation of growth GO:0045927 104 0.014
regulation of ossification GO:0030278 112 0.014
regulation of transmembrane transport GO:0034762 128 0.014
sensory perception of sound GO:0007605 97 0.014
ameboidal type cell migration GO:0001667 128 0.014
epithelial cell development GO:0002064 159 0.014
Rat
negative regulation of cell motility GO:2000146 61 0.013
Rat
insulin secretion GO:0030073 89 0.013
macromolecule catabolic process GO:0009057 281 0.013
protein catabolic process GO:0030163 221 0.013
regulation of intracellular transport GO:0032386 159 0.013
positive regulation of secretion GO:0051047 130 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
axon ensheathment GO:0008366 76 0.013
axonogenesis GO:0007409 274 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
positive regulation of kinase activity GO:0033674 155 0.013
Mouse
positive regulation of gtpase activity GO:0043547 85 0.013
myelination GO:0042552 74 0.013
cardiocyte differentiation GO:0035051 87 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
pole plasm assembly GO:0007315 2 0.013
protein maturation GO:0051604 176 0.013
negative regulation of growth GO:0045926 99 0.013
learning or memory GO:0007611 148 0.013
Worm
lymphocyte differentiation GO:0030098 242 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
negative regulation of cell migration GO:0030336 59 0.013
Rat
regulation of synaptic plasticity GO:0048167 87 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
Mouse
anatomical structure homeostasis GO:0060249 145 0.013
asymmetric neuroblast division GO:0055059 1 0.013
regulation of postsynaptic membrane potential GO:0060078 48 0.013
wound healing GO:0042060 157 0.013
protein localization to membrane GO:0072657 108 0.013
Rat
regulation of lipid metabolic process GO:0019216 118 0.013
carbohydrate metabolic process GO:0005975 230 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cardiac muscle tissue development GO:0048738 130 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
cation homeostasis GO:0055080 212 0.013
actomyosin structure organization GO:0031032 56 0.012
bone mineralization GO:0030282 54 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of cellular response to stress GO:0080135 159 0.012
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.012
blood vessel morphogenesis GO:0048514 285 0.012
apoptotic signaling pathway GO:0097190 306 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
regulation of ion transport GO:0043269 215 0.012
response to radiation GO:0009314 165 0.012
cellular potassium ion transport GO:0071804 43 0.012
biomineral tissue development GO:0031214 64 0.012
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.012
multi organism behavior GO:0051705 62 0.012
circulatory system process GO:0003013 197 0.012
skeletal muscle organ development GO:0060538 163 0.012
regulation of microtubule cytoskeleton organization GO:0070507 37 0.012
ear morphogenesis GO:0042471 118 0.012
regulation of asymmetric cell division GO:0009786 4 0.012
male courtship behavior GO:0008049 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
dna metabolic process GO:0006259 303 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
inflammatory response GO:0006954 244 0.012
epithelial tube formation GO:0072175 130 0.012
neuron apoptotic process GO:0051402 142 0.012
synaptic transmission gabaergic GO:0051932 19 0.012
positive regulation of hormone secretion GO:0046887 38 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
meiotic nuclear division GO:0007126 115 0.012
regulation of biomineral tissue development GO:0070167 33 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
regulation of cell growth GO:0001558 91 0.012
peptide transport GO:0015833 133 0.011
protein processing GO:0016485 163 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
neuron death GO:0070997 154 0.011
sensory perception GO:0007600 245 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
mitotic cytokinesis GO:0000281 4 0.011
positive regulation of rho gtpase activity GO:0032321 41 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
Rat
determination of left right symmetry GO:0007368 80 0.011
multicellular organism growth GO:0035264 161 0.011
memory GO:0007613 58 0.011
Worm
potassium ion transmembrane transport GO:0071805 43 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of neuron projection development GO:0010975 169 0.011
Rat
bone morphogenesis GO:0060349 78 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
endocytosis GO:0006897 168 0.011
Human
gland development GO:0048732 330 0.011
embryonic skeletal system development GO:0048706 120 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
attachment of spindle microtubules to kinetochore GO:0008608 4 0.011
regulation of neural precursor cell proliferation GO:2000177 70 0.011
primary neural tube formation GO:0014020 95 0.011
neuron projection guidance GO:0097485 141 0.011
appendage development GO:0048736 166 0.011
response to light stimulus GO:0009416 135 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
sequestering of calcium ion GO:0051208 18 0.011
cell division GO:0051301 120 0.011
regulation of hydrolase activity GO:0051336 246 0.011
Human
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
actin filament polymerization GO:0030041 44 0.011
axon target recognition GO:0007412 4 0.011
b cell differentiation GO:0030183 78 0.011
methylation GO:0032259 134 0.011
regulation of proteolysis GO:0030162 164 0.011
cell substrate adhesion GO:0031589 130 0.011
body morphogenesis GO:0010171 45 0.011
divalent inorganic cation transport GO:0072511 178 0.011
glycosylation GO:0070085 62 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
odontogenesis GO:0042476 78 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
asymmetric stem cell division GO:0098722 3 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
neural tube formation GO:0001841 108 0.011
microtubule polymerization or depolymerization GO:0031109 26 0.011
response to monosaccharide GO:0034284 67 0.011
cell activation involved in immune response GO:0002263 126 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
regulation of cell activation GO:0050865 289 0.010
negative regulation of neuron death GO:1901215 98 0.010
palate development GO:0060021 76 0.010
leukocyte migration GO:0050900 124 0.010
regulation of vasculature development GO:1901342 88 0.010
negative regulation of organelle organization GO:0010639 90 0.010
oxidation reduction process GO:0055114 342 0.010
cell recognition GO:0008037 83 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
regulation of striated muscle cell differentiation GO:0051153 81 0.010
heart process GO:0003015 94 0.010
rhythmic process GO:0048511 174 0.010
mesonephric epithelium development GO:0072163 94 0.010
regulation of feeding behavior GO:0060259 3 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.010
cellular response to acid chemical GO:0071229 68 0.010
regulation of defense response GO:0031347 233 0.010
epithelium migration GO:0090132 63 0.010
cerebellum development GO:0021549 77 0.010
tissue remodeling GO:0048771 102 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
Mouse
regulation of voltage gated calcium channel activity GO:1901385 4 0.010
regulation of actin filament based process GO:0032970 99 0.010
response to amino acid GO:0043200 37 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
Rat
cellular response to molecule of bacterial origin GO:0071219 83 0.010
negative regulation of fat cell differentiation GO:0045599 36 0.010
peptidyl serine modification GO:0018209 83 0.010
regulation of body fluid levels GO:0050878 162 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
Mouse
regulation of response to wounding GO:1903034 189 0.010
male gonad development GO:0008584 88 0.010
fertilization GO:0009566 127 0.010
regulation of cell adhesion GO:0030155 154 0.010

Magi2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
central nervous system disease DOID:331 0 0.021
brain disease DOID:936 0 0.018
musculoskeletal system disease DOID:17 0 0.014