Mus musculus

75 known processes

Cbx4

chromobox homolog 4 (Drosophila Pc class)

(Aliases: PC2,MGC143698,MPc2,MGC143697)

Cbx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.079
regulation of cellular amine metabolic process GO:0033238 20 0.067
protein modification by small protein conjugation GO:0032446 187 0.067
covalent chromatin modification GO:0016569 163 0.063
Mouse
cellular ketone metabolic process GO:0042180 84 0.062
chromatin modification GO:0016568 187 0.059
Mouse
protein ubiquitination GO:0016567 171 0.057
Mouse
cellular amino acid metabolic process GO:0006520 103 0.051
lung development GO:0030324 164 0.049
nucleoside phosphate metabolic process GO:0006753 338 0.047
nucleotide metabolic process GO:0009117 332 0.046
skeletal system development GO:0001501 356 0.046
cellular macromolecule catabolic process GO:0044265 206 0.046
purine nucleotide metabolic process GO:0006163 302 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
negative regulation of nervous system development GO:0051961 156 0.042
amine metabolic process GO:0009308 45 0.042
regulation of cell cycle GO:0051726 281 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
membrane organization GO:0061024 245 0.039
chromatin organization GO:0006325 206 0.039
Mouse
cellular response to lipid GO:0071396 145 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
spermatogenesis GO:0007283 284 0.037
ribose phosphate metabolic process GO:0019693 291 0.036
purine ribonucleoside catabolic process GO:0046130 205 0.034
dna metabolic process GO:0006259 303 0.034
regionalization GO:0003002 337 0.034
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.034
retrograde transport endosome to golgi GO:0042147 2 0.034
mitotic cell cycle process GO:1903047 159 0.034
cellular amine metabolic process GO:0044106 44 0.033
macromolecule catabolic process GO:0009057 281 0.032
peptidyl amino acid modification GO:0018193 336 0.032
gland development GO:0048732 330 0.031
Mouse
cation transmembrane transport GO:0098655 266 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
regulation of organelle organization GO:0033043 289 0.031
intracellular protein transport GO:0006886 204 0.030
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
leukocyte differentiation GO:0002521 342 0.030
axonogenesis GO:0007409 274 0.030
myeloid cell differentiation GO:0030099 233 0.030
methylation GO:0032259 134 0.030
t cell activation GO:0042110 289 0.030
regulation of cell activation GO:0050865 289 0.029
respiratory system development GO:0060541 190 0.029
lymphocyte differentiation GO:0030098 242 0.029
respiratory tube development GO:0030323 167 0.029
anion transport GO:0006820 177 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
histone modification GO:0016570 159 0.028
Mouse
purine nucleoside catabolic process GO:0006152 205 0.027
ubiquitin dependent protein catabolic process GO:0006511 129 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
regulation of clathrin mediated endocytosis GO:2000369 4 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
macromolecule methylation GO:0043414 120 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
positive regulation of cell activation GO:0050867 158 0.026
ion transmembrane transport GO:0034220 361 0.026
negative regulation of molecular function GO:0044092 258 0.026
male gamete generation GO:0048232 285 0.026
transmembrane transport GO:0055085 412 0.026
purine containing compound metabolic process GO:0072521 311 0.026
single organism cell adhesion GO:0098602 156 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
gene silencing GO:0016458 38 0.025
Fly
nucleoside catabolic process GO:0009164 206 0.024
dephosphorylation GO:0016311 129 0.024
protein catabolic process GO:0030163 221 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
regulation of leukocyte differentiation GO:1902105 159 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
purine containing compound catabolic process GO:0072523 213 0.023
synaptic transmission GO:0007268 329 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
intra golgi vesicle mediated transport GO:0006891 1 0.022
cell adhesion GO:0007155 329 0.022
carbohydrate metabolic process GO:0005975 230 0.022
response to lipopolysaccharide GO:0032496 128 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
fat cell differentiation GO:0045444 160 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
mapk cascade GO:0000165 281 0.021
immune effector process GO:0002252 321 0.021
histone lysine methylation GO:0034968 50 0.021
neural tube development GO:0021915 160 0.021
negative regulation of cellular component organization GO:0051129 194 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
heterocycle catabolic process GO:0046700 280 0.020
rho protein signal transduction GO:0007266 32 0.020
negative regulation of growth GO:0045926 99 0.020
muscle tissue development GO:0060537 308 0.020
skeletal system morphogenesis GO:0048705 203 0.020
positive regulation of protein modification process GO:0031401 299 0.020
ossification GO:0001503 216 0.020
cellular protein catabolic process GO:0044257 155 0.020
nucleoside metabolic process GO:0009116 246 0.019
regulation of inflammatory response GO:0050727 147 0.019
nitrogen compound transport GO:0071705 271 0.019
organelle localization GO:0051640 179 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
heart contraction GO:0060047 93 0.019
oxidation reduction process GO:0055114 342 0.019
apoptotic signaling pathway GO:0097190 306 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
negative regulation of immune system process GO:0002683 209 0.019
mitotic cell cycle GO:0000278 195 0.019
Fly
carbohydrate derivative catabolic process GO:1901136 231 0.019
histone acetylation GO:0016573 41 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
positive regulation of dna templated transcription elongation GO:0032786 2 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.018
regulation of cell projection organization GO:0031344 206 0.018
protein methylation GO:0006479 81 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
response to oxidative stress GO:0006979 123 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
cell type specific apoptotic process GO:0097285 268 0.018
response to organic cyclic compound GO:0014070 198 0.018
positive regulation of nervous system development GO:0051962 221 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
regulation of transferase activity GO:0051338 263 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
cellular response to acid chemical GO:0071229 68 0.017
regulation of t cell activation GO:0050863 170 0.017
organophosphate catabolic process GO:0046434 232 0.017
erythrocyte differentiation GO:0030218 88 0.017
t cell differentiation GO:0030217 174 0.017
forebrain development GO:0030900 302 0.017
organic hydroxy compound transport GO:0015850 93 0.017
chemotaxis GO:0006935 247 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
action potential GO:0001508 78 0.017
cellular lipid metabolic process GO:0044255 323 0.017
lipid localization GO:0010876 126 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
establishment of organelle localization GO:0051656 122 0.017
localization within membrane GO:0051668 4 0.016
regulation of t cell differentiation GO:0045580 83 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
blood circulation GO:0008015 195 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
striated muscle tissue development GO:0014706 293 0.016
internal protein amino acid acetylation GO:0006475 42 0.016
cellular protein complex assembly GO:0043623 116 0.016
response to organonitrogen compound GO:0010243 246 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
segmentation GO:0035282 93 0.016
Fly
negative regulation of transferase activity GO:0051348 85 0.016
tube formation GO:0035148 140 0.016
cell maturation GO:0048469 127 0.016
Fly
bone development GO:0060348 120 0.016
aromatic compound catabolic process GO:0019439 286 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
dna alkylation GO:0006305 43 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
developmental maturation GO:0021700 193 0.016
Fly
peptidyl lysine modification GO:0018205 77 0.015
regulation of cellular response to stress GO:0080135 159 0.015
protein localization to organelle GO:0033365 185 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
bmp signaling pathway GO:0030509 93 0.015
ras protein signal transduction GO:0007265 77 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
endocytosis GO:0006897 168 0.015
placenta development GO:0001890 140 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
homeostasis of number of cells GO:0048872 210 0.015
regulation of hormone levels GO:0010817 211 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
protein targeting GO:0006605 143 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
cytoplasmic transport GO:0016482 234 0.015
leukocyte proliferation GO:0070661 172 0.015
negative regulation of synapse assembly GO:0051964 3 0.015
regulation of neuron differentiation GO:0045664 281 0.015
response to inorganic substance GO:0010035 96 0.015
cell division GO:0051301 120 0.015
dna modification GO:0006304 50 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
positive regulation of immature t cell proliferation GO:0033091 4 0.015
glucose homeostasis GO:0042593 128 0.015
purine nucleotide biosynthetic process GO:0006164 65 0.015
regulation of secretion GO:0051046 274 0.014
microtubule based process GO:0007017 236 0.014
camera type eye development GO:0043010 266 0.014
multicellular organism growth GO:0035264 161 0.014
epithelial cell proliferation GO:0050673 174 0.014
compound eye development GO:0048749 1 0.014
regulation of secretion by cell GO:1903530 249 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
sequestering of metal ion GO:0051238 19 0.014
glycoprotein metabolic process GO:0009100 116 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
nuclear transport GO:0051169 139 0.014
neural tube formation GO:0001841 108 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
mitochondrion organization GO:0007005 134 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
regulation of histone modification GO:0031056 56 0.014
muscle cell differentiation GO:0042692 261 0.014
organic anion transport GO:0015711 137 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
alcohol metabolic process GO:0006066 116 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
t cell differentiation in thymus GO:0033077 77 0.014
b cell activation GO:0042113 161 0.014
wnt signaling pathway GO:0016055 188 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
multicellular organismal signaling GO:0035637 91 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
cardiac chamber development GO:0003205 108 0.014
regulation of binding GO:0051098 111 0.014
response to radiation GO:0009314 165 0.014
Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.013
cellular chemical homeostasis GO:0055082 215 0.013
transmission of nerve impulse GO:0019226 76 0.013
regulation of response to wounding GO:1903034 189 0.013
embryonic skeletal system morphogenesis GO:0048704 91 0.013
lipid transport GO:0006869 98 0.013
rna interference GO:0016246 2 0.013
myosin filament assembly GO:0031034 2 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
organelle fission GO:0048285 170 0.013
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.013
Fly
regulation of homeostatic process GO:0032844 182 0.013
regulation of membrane potential GO:0042391 192 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
metal ion homeostasis GO:0055065 189 0.013
negative regulation of cell cycle GO:0045786 123 0.013
regulation of engulfment of apoptotic cell GO:1901074 2 0.013
gene silencing by rna GO:0031047 19 0.013
regulation of system process GO:0044057 200 0.013
regulation of defense response GO:0031347 233 0.013
inter male aggressive behavior GO:0002121 3 0.013
interleukin 8 production GO:0032637 4 0.013
carbohydrate homeostasis GO:0033500 128 0.013
cytokine production GO:0001816 319 0.013
response to acid chemical GO:0001101 111 0.012
divalent inorganic cation transport GO:0072511 178 0.012
cation transport GO:0006812 399 0.012
circadian rhythm GO:0007623 114 0.012
histone methylation GO:0016571 71 0.012
regulation of endocytosis GO:0030100 69 0.012
circulatory system process GO:0003013 197 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of neuron death GO:1901214 134 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
internal peptidyl lysine acetylation GO:0018393 42 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
myosin filament organization GO:0031033 3 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
response to peptide GO:1901652 136 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
fat soluble vitamin biosynthetic process GO:0042362 4 0.012
dna repair GO:0006281 107 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
stem cell differentiation GO:0048863 268 0.012
germ cell development GO:0007281 185 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
endomembrane system organization GO:0010256 147 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
b cell differentiation GO:0030183 78 0.012
protein alkylation GO:0008213 81 0.011
organic acid transport GO:0015849 101 0.011
positive regulation of t cell activation GO:0050870 101 0.011
regulation of kinase activity GO:0043549 249 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
intracellular mrna localization GO:0008298 4 0.011
development of primary sexual characteristics GO:0045137 143 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of mapk cascade GO:0043408 248 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
rhythmic process GO:0048511 174 0.011
response to sterol GO:0036314 4 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
negative regulation of cell development GO:0010721 169 0.011
negative regulation of response to wounding GO:1903035 77 0.011
regulation of protein transport GO:0051223 163 0.011
regulation of cell growth GO:0001558 91 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
maintenance of location GO:0051235 89 0.011
response to light stimulus GO:0009416 135 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
cell growth GO:0016049 130 0.011
cytokinetic process GO:0032506 2 0.011
regulation of protein complex assembly GO:0043254 83 0.011
response to retinoic acid GO:0032526 56 0.011
regulation of ossification GO:0030278 112 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
cognition GO:0050890 149 0.011
positive regulation of cell development GO:0010720 237 0.011
positive regulation of secretion GO:0051047 130 0.011
transcription from rna polymerase iii promoter GO:0006383 3 0.011
regulation of cell migration GO:0030334 219 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
protein acylation GO:0043543 64 0.011
gonad development GO:0008406 141 0.011
positive regulation of chromatin modification GO:1903310 28 0.011
positive regulation of organelle organization GO:0010638 128 0.011
dna recombination GO:0006310 92 0.011
protein import into nucleus GO:0006606 95 0.011
hormone secretion GO:0046879 128 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
alpha beta t cell activation GO:0046631 91 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
positive regulation of growth GO:0045927 104 0.011
actin cytoskeleton organization GO:0030036 220 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
neuron death GO:0070997 154 0.011
gtp metabolic process GO:0046039 144 0.011
innate immune response GO:0045087 157 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.010
dna methylation GO:0006306 43 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
embryonic skeletal system development GO:0048706 120 0.010
exocytosis GO:0006887 121 0.010
regulation of feeding behavior GO:0060259 3 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
neuron apoptotic process GO:0051402 142 0.010
regulation of chromatin organization GO:1902275 57 0.010
regulation of cell cycle process GO:0010564 160 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
cellular homeostasis GO:0019725 240 0.010
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
calcium ion homeostasis GO:0055074 127 0.010
heart process GO:0003015 94 0.010
skin development GO:0043588 220 0.010
neuronal action potential GO:0019228 54 0.010
his purkinje system development GO:0003164 4 0.010
spermatid differentiation GO:0048515 115 0.010
wound healing GO:0042060 157 0.010
Fly
positive regulation of lymphocyte differentiation GO:0045621 61 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
toxin transport GO:1901998 38 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
asymmetric stem cell division GO:0098722 3 0.010
positive regulation of immune effector process GO:0002699 107 0.010
negative regulation of kinase activity GO:0033673 81 0.010
midgut development GO:0007494 4 0.010

Cbx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.022
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
inherited metabolic disorder DOID:655 0 0.015
central nervous system disease DOID:331 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
disease of mental health DOID:150 0 0.011
brain disease DOID:936 0 0.010