Mus musculus

32 known processes

Sprn

shadow of prion protein

(Aliases: C630041J07)

Sprn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.115
divalent inorganic cation transport GO:0072511 178 0.110
amine metabolic process GO:0009308 45 0.109
cellular lipid metabolic process GO:0044255 323 0.094
transmembrane transport GO:0055085 412 0.083
heart contraction GO:0060047 93 0.077
cation homeostasis GO:0055080 212 0.074
regulation of cellular ketone metabolic process GO:0010565 66 0.072
cation transport GO:0006812 399 0.072
muscle system process GO:0003012 141 0.068
regulation of system process GO:0044057 200 0.067
purine ribonucleotide catabolic process GO:0009154 208 0.065
heart process GO:0003015 94 0.062
carbohydrate derivative biosynthetic process GO:1901137 183 0.062
regulation of membrane potential GO:0042391 192 0.061
blood circulation GO:0008015 195 0.059
organonitrogen compound biosynthetic process GO:1901566 192 0.057
regulation of ion transport GO:0043269 215 0.057
g protein coupled receptor signaling pathway GO:0007186 243 0.053
purine nucleotide metabolic process GO:0006163 302 0.050
inorganic cation transmembrane transport GO:0098662 207 0.050
regulation of secretion GO:0051046 274 0.050
immune effector process GO:0002252 321 0.050
cellular amino acid metabolic process GO:0006520 103 0.048
ossification GO:0001503 216 0.047
nucleoside phosphate metabolic process GO:0006753 338 0.047
response to organonitrogen compound GO:0010243 246 0.046
cellular amine metabolic process GO:0044106 44 0.045
regulation of muscle contraction GO:0006937 49 0.045
muscle contraction GO:0006936 101 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.043
regulation of ion transmembrane transport GO:0034765 119 0.043
regulation of metal ion transport GO:0010959 106 0.042
cellular ketone metabolic process GO:0042180 84 0.042
sequestering of calcium ion GO:0051208 18 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
calcium ion transport GO:0006816 159 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.038
purine nucleotide catabolic process GO:0006195 211 0.038
organonitrogen compound catabolic process GO:1901565 264 0.038
circulatory system process GO:0003013 197 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
ion transmembrane transport GO:0034220 361 0.036
maintenance of location GO:0051235 89 0.036
cellular chemical homeostasis GO:0055082 215 0.035
neuronal action potential GO:0019228 54 0.035
cardiac muscle contraction GO:0060048 32 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
purine containing compound metabolic process GO:0072521 311 0.034
hexose metabolic process GO:0019318 98 0.034
sensory perception GO:0007600 245 0.034
skeletal system development GO:0001501 356 0.033
purine ribonucleoside catabolic process GO:0046130 205 0.033
protein secretion GO:0009306 111 0.031
divalent metal ion transport GO:0070838 172 0.031
aromatic compound catabolic process GO:0019439 286 0.030
response to lipopolysaccharide GO:0032496 128 0.030
regulation of protein localization GO:0032880 231 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
nitrogen compound transport GO:0071705 271 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
regulation of transmembrane transport GO:0034762 128 0.029
epithelial cell proliferation GO:0050673 174 0.029
cytokine production GO:0001816 319 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
metal ion homeostasis GO:0055065 189 0.029
purine nucleoside metabolic process GO:0042278 241 0.028
regulation of blood circulation GO:1903522 93 0.028
positive regulation of ion transport GO:0043270 65 0.028
organophosphate biosynthetic process GO:0090407 122 0.028
regulation of synaptic plasticity GO:0048167 87 0.028
heterocycle catabolic process GO:0046700 280 0.028
cellular homeostasis GO:0019725 240 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
cation transmembrane transport GO:0098655 266 0.027
calcium ion homeostasis GO:0055074 127 0.026
carbohydrate metabolic process GO:0005975 230 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
fat cell differentiation GO:0045444 160 0.026
cellular response to lipid GO:0071396 145 0.026
regulation of heart contraction GO:0008016 77 0.026
memory GO:0007613 58 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
glycosyl compound metabolic process GO:1901657 246 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
sodium ion transport GO:0006814 73 0.025
action potential GO:0001508 78 0.025
establishment of protein localization to organelle GO:0072594 118 0.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
mapk cascade GO:0000165 281 0.024
cellular divalent inorganic cation homeostasis GO:0072503 127 0.024
membrane organization GO:0061024 245 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.024
positive regulation of protein modification process GO:0031401 299 0.024
lipid biosynthetic process GO:0008610 179 0.023
protein localization to nucleus GO:0034504 121 0.023
positive regulation of secretion GO:0051047 130 0.023
single organism cell adhesion GO:0098602 156 0.023
purine containing compound biosynthetic process GO:0072522 70 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
regulation of blood pressure GO:0008217 93 0.023
regulation of hydrolase activity GO:0051336 246 0.022
regulation of anatomical structure size GO:0090066 178 0.022
regulation of calcium ion transport GO:0051924 69 0.022
response to pain GO:0048265 26 0.022
apoptotic signaling pathway GO:0097190 306 0.022
monoamine transport GO:0015844 33 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
intracellular protein transport GO:0006886 204 0.022
sequestering of metal ion GO:0051238 19 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
cyclic purine nucleotide metabolic process GO:0052652 43 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
nucleoside metabolic process GO:0009116 246 0.021
multicellular organismal signaling GO:0035637 91 0.021
protein localization to organelle GO:0033365 185 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
cytosolic calcium ion homeostasis GO:0051480 70 0.021
glycerolipid metabolic process GO:0046486 122 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
developmental maturation GO:0021700 193 0.021
hormone secretion GO:0046879 128 0.020
intracellular mrna localization GO:0008298 4 0.020
regulation of ion transmembrane transporter activity GO:0032412 54 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
muscle tissue development GO:0060537 308 0.020
muscle fiber development GO:0048747 76 0.020
establishment of organelle localization GO:0051656 122 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
macromolecule catabolic process GO:0009057 281 0.020
regulation of synaptic transmission gabaergic GO:0032228 17 0.020
cell adhesion GO:0007155 329 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
gland development GO:0048732 330 0.019
response to peptide GO:1901652 136 0.019
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.019
fatty acid metabolic process GO:0006631 121 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.019
regulation of kinase activity GO:0043549 249 0.019
erk1 and erk2 cascade GO:0070371 77 0.019
organophosphate catabolic process GO:0046434 232 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
synapse organization GO:0050808 125 0.019
calcium ion transmembrane transport GO:0070588 85 0.019
pallium development GO:0021543 120 0.019
monocarboxylic acid metabolic process GO:0032787 191 0.019
purine containing compound catabolic process GO:0072523 213 0.019
regulation of muscle system process GO:0090257 80 0.019
adult locomotory behavior GO:0008344 91 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
regulation of ossification GO:0030278 112 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
ras protein signal transduction GO:0007265 77 0.018
peptidyl amino acid modification GO:0018193 336 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
oocyte construction GO:0007308 2 0.018
small molecule biosynthetic process GO:0044283 132 0.018
protein catabolic process GO:0030163 221 0.018
substantia nigra development GO:0021762 2 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
camera type eye development GO:0043010 266 0.018
muscle cell differentiation GO:0042692 261 0.018
vascular process in circulatory system GO:0003018 62 0.018
nuclear import GO:0051170 95 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
limbic system development GO:0021761 72 0.018
glucose homeostasis GO:0042593 128 0.018
neuron neuron synaptic transmission GO:0007270 69 0.018
cellular ion homeostasis GO:0006873 165 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
negative regulation of nervous system development GO:0051961 156 0.018
striated muscle contraction GO:0006941 45 0.018
response to inorganic substance GO:0010035 96 0.017
regulation of cell cycle GO:0051726 281 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
male gamete generation GO:0048232 285 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
regulation of protein kinase activity GO:0045859 232 0.017
establishment of blood nerve barrier GO:0008065 3 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of cell migration GO:0030334 219 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
telencephalon development GO:0021537 186 0.017
positive regulation of protein secretion GO:0050714 52 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
organelle localization GO:0051640 179 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.016
monosaccharide metabolic process GO:0005996 106 0.016
regulation of cellular response to stress GO:0080135 159 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.016
positive regulation of gtp catabolic process GO:0033126 85 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
smooth muscle contraction GO:0006939 44 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
regulation of secretion by cell GO:1903530 249 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
cyclic nucleotide metabolic process GO:0009187 59 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
glycoprotein biosynthetic process GO:0009101 89 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
glycoprotein metabolic process GO:0009100 116 0.016
response to organic cyclic compound GO:0014070 198 0.015
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.015
glucose transport GO:0015758 56 0.015
forebrain development GO:0030900 302 0.015
nucleotide metabolic process GO:0009117 332 0.015
anion transport GO:0006820 177 0.015
regulation of voltage gated calcium channel activity GO:1901385 4 0.015
purine nucleotide biosynthetic process GO:0006164 65 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
protein import GO:0017038 101 0.015
transmission of nerve impulse GO:0019226 76 0.015
regulation of carbohydrate metabolic process GO:0006109 75 0.015
regulation of protein transport GO:0051223 163 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
endomembrane system organization GO:0010256 147 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
negative regulation of cell migration GO:0030336 59 0.015
response to alkaloid GO:0043279 34 0.015
regulation of cell adhesion GO:0030155 154 0.015
locomotory behavior GO:0007626 195 0.015
spermatogenesis GO:0007283 284 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
detection of stimulus GO:0051606 84 0.015
positive regulation of kinase activity GO:0033674 155 0.015
wound healing GO:0042060 157 0.015
cytoplasmic transport GO:0016482 234 0.015
regulation of peptide secretion GO:0002791 77 0.015
adult behavior GO:0030534 135 0.015
conditioned taste aversion GO:0001661 4 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
regulation of transferase activity GO:0051338 263 0.015
regulation of serotonin secretion GO:0014062 3 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
nucleotide catabolic process GO:0009166 217 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
leukocyte proliferation GO:0070661 172 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of mapk cascade GO:0043408 248 0.014
regulation of protein secretion GO:0050708 82 0.014
amide transport GO:0042886 138 0.014
peptidyl serine modification GO:0018209 83 0.014
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
placenta development GO:0001890 140 0.014
regulation of organelle organization GO:0033043 289 0.014
striated muscle tissue development GO:0014706 293 0.014
striated muscle cell development GO:0055002 125 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
sulfur compound metabolic process GO:0006790 100 0.014
ribose phosphate biosynthetic process GO:0046390 59 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
innate immune response GO:0045087 157 0.013
regulation of cytokine production GO:0001817 266 0.013
rap protein signal transduction GO:0032486 3 0.013
response to radiation GO:0009314 165 0.013
regulation of hormone levels GO:0010817 211 0.013
monosaccharide transport GO:0015749 58 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
regulation of systemic arterial blood pressure GO:0003073 61 0.013
positive regulation of epithelial cell proliferation GO:0050679 68 0.013
carboxylic acid transport GO:0046942 100 0.013
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.013
regulation of blood vessel size GO:0050880 56 0.013
regulation of cell motility GO:2000145 236 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
regulation of multi organism process GO:0043900 111 0.013
sensory perception of touch GO:0050975 2 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
renal system development GO:0072001 225 0.013
proteoglycan biosynthetic process GO:0030166 20 0.012
gtp metabolic process GO:0046039 144 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
adrenergic receptor signaling pathway GO:0071875 13 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
carbohydrate homeostasis GO:0033500 128 0.012
protein targeting GO:0006605 143 0.012
regulation of homeostatic process GO:0032844 182 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
synaptic vesicle localization GO:0097479 59 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
oocyte axis specification GO:0007309 2 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
response to acid chemical GO:0001101 111 0.012
response to metal ion GO:0010038 47 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
organic anion transport GO:0015711 137 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.012
activation of adenylate cyclase activity GO:0007190 4 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
female genitalia morphogenesis GO:0048807 3 0.012
nucleoside catabolic process GO:0009164 206 0.012
peptide secretion GO:0002790 114 0.012
cyclic nucleotide biosynthetic process GO:0009190 44 0.012
detection of abiotic stimulus GO:0009582 60 0.012
defense response to other organism GO:0098542 197 0.012
regulation of synapse structural plasticity GO:0051823 4 0.012
oxidation reduction process GO:0055114 342 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
plasma membrane organization GO:0007009 90 0.012
skin development GO:0043588 220 0.012
hexose transport GO:0008645 56 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
response to oxidative stress GO:0006979 123 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
negative regulation of growth GO:0045926 99 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
gliogenesis GO:0042063 141 0.011
regulation of tube size GO:0035150 57 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
regulation of response to wounding GO:1903034 189 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
negative regulation of cell development GO:0010721 169 0.011
positive regulation of fatty acid oxidation GO:0046321 4 0.011
cytokine secretion GO:0050663 72 0.011
negative regulation of serotonin secretion GO:0014063 2 0.011
regulation of striated muscle contraction GO:0006942 25 0.011
multicellular organismal response to stress GO:0033555 62 0.011
cell division GO:0051301 120 0.010
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.010
positive regulation of vasoconstriction GO:0045907 4 0.010
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
glutamate receptor signaling pathway GO:0007215 35 0.010
protein maturation GO:0051604 176 0.010
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
carbohydrate transport GO:0008643 62 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
operant conditioning GO:0035106 2 0.010
regulation of cd24 biosynthetic process GO:2000559 1 0.010
regulation of peptide transport GO:0090087 91 0.010
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.010
bone development GO:0060348 120 0.010
alpha amino acid metabolic process GO:1901605 59 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.010
cognition GO:0050890 149 0.010
positive regulation of carbohydrate metabolic process GO:0045913 30 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
positive regulation of transferase activity GO:0051347 167 0.010
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.010
positive regulation of nucleotide catabolic process GO:0030813 88 0.010
glucose metabolic process GO:0006006 92 0.010
positive regulation of necrotic cell death GO:0010940 1 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
microtubule polymerization or depolymerization GO:0031109 26 0.010
gtp catabolic process GO:0006184 143 0.010

Sprn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.033
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
sensory system disease DOID:0050155 0 0.012