Mus musculus

0 known processes

Pls1

plastin 1 (I-isoform)

(Aliases: AI427122)

Pls1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.079
cellular amino acid metabolic process GO:0006520 103 0.065
cation transport GO:0006812 399 0.060
purine containing compound metabolic process GO:0072521 311 0.057
organic cyclic compound catabolic process GO:1901361 295 0.052
neuronal action potential GO:0019228 54 0.051
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
cellular lipid metabolic process GO:0044255 323 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.048
ribonucleoside metabolic process GO:0009119 245 0.047
glycosyl compound metabolic process GO:1901657 246 0.047
purine ribonucleoside metabolic process GO:0046128 241 0.046
nucleoside triphosphate metabolic process GO:0009141 230 0.045
nucleoside metabolic process GO:0009116 246 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.043
aromatic compound catabolic process GO:0019439 286 0.043
heterocycle catabolic process GO:0046700 280 0.043
organonitrogen compound catabolic process GO:1901565 264 0.042
oxidation reduction process GO:0055114 342 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.040
purine nucleoside metabolic process GO:0042278 241 0.040
nitrogen compound transport GO:0071705 271 0.040
anion transport GO:0006820 177 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
cell adhesion GO:0007155 329 0.038
regulation of membrane potential GO:0042391 192 0.038
amine metabolic process GO:0009308 45 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
nucleotide metabolic process GO:0009117 332 0.037
purine ribonucleotide metabolic process GO:0009150 290 0.037
ras protein signal transduction GO:0007265 77 0.036
cellular ketone metabolic process GO:0042180 84 0.036
regulation of cellular catabolic process GO:0031329 242 0.035
cellular amine metabolic process GO:0044106 44 0.035
purine nucleotide catabolic process GO:0006195 211 0.035
organophosphate catabolic process GO:0046434 232 0.035
purine ribonucleoside catabolic process GO:0046130 205 0.034
myeloid cell differentiation GO:0030099 233 0.034
regulation of organelle organization GO:0033043 289 0.034
glycosyl compound catabolic process GO:1901658 206 0.033
ion transmembrane transport GO:0034220 361 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.032
regulation of hydrolase activity GO:0051336 246 0.032
monocarboxylic acid metabolic process GO:0032787 191 0.032
cation transmembrane transport GO:0098655 266 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
ribonucleotide metabolic process GO:0009259 291 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
cellular homeostasis GO:0019725 240 0.031
purine containing compound catabolic process GO:0072523 213 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
nucleoside catabolic process GO:0009164 206 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
membrane organization GO:0061024 245 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
lipid biosynthetic process GO:0008610 179 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
nucleotide catabolic process GO:0009166 217 0.030
leukocyte differentiation GO:0002521 342 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
cellular chemical homeostasis GO:0055082 215 0.029
ribonucleoside catabolic process GO:0042454 206 0.029
macromolecule catabolic process GO:0009057 281 0.028
maintenance of location GO:0051235 89 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
purine nucleotide metabolic process GO:0006163 302 0.027
actin cytoskeleton organization GO:0030036 220 0.027
response to organonitrogen compound GO:0010243 246 0.027
inorganic cation transmembrane transport GO:0098662 207 0.026
purine ribonucleotide catabolic process GO:0009154 208 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
transmission of nerve impulse GO:0019226 76 0.026
gtp catabolic process GO:0006184 143 0.026
cytoplasmic transport GO:0016482 234 0.025
endomembrane system organization GO:0010256 147 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
multicellular organismal signaling GO:0035637 91 0.025
action potential GO:0001508 78 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
cellular ion homeostasis GO:0006873 165 0.025
cation homeostasis GO:0055080 212 0.024
regulation of cell motility GO:2000145 236 0.024
organic anion transport GO:0015711 137 0.024
homeostasis of number of cells GO:0048872 210 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
regulation of hormone levels GO:0010817 211 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
sequestering of calcium ion GO:0051208 18 0.023
sensory perception GO:0007600 245 0.023
regulation of secretion by cell GO:1903530 249 0.023
immune effector process GO:0002252 321 0.023
cytokine production GO:0001816 319 0.022
glycerolipid metabolic process GO:0046486 122 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
peptidyl amino acid modification GO:0018193 336 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
cellular metal ion homeostasis GO:0006875 151 0.022
regulation of secretion GO:0051046 274 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
amino acid transmembrane transport GO:0003333 37 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
positive regulation of hydrolase activity GO:0051345 148 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
regulation of ion transport GO:0043269 215 0.021
divalent inorganic cation transport GO:0072511 178 0.021
intracellular protein transport GO:0006886 204 0.021
microtubule based process GO:0007017 236 0.021
regulation of cell migration GO:0030334 219 0.021
protein catabolic process GO:0030163 221 0.021
peptide transport GO:0015833 133 0.021
carbohydrate metabolic process GO:0005975 230 0.021
actin filament organization GO:0007015 113 0.020
organic acid transport GO:0015849 101 0.020
regulation of cell projection organization GO:0031344 206 0.020
rho protein signal transduction GO:0007266 32 0.020
regulation of cell activation GO:0050865 289 0.020
sulfur compound metabolic process GO:0006790 100 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of chloride transport GO:2001225 2 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
spermatogenesis GO:0007283 284 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
small molecule biosynthetic process GO:0044283 132 0.019
protein targeting GO:0006605 143 0.019
t cell activation GO:0042110 289 0.019
male gamete generation GO:0048232 285 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
response to extracellular stimulus GO:0009991 127 0.018
inflammatory response GO:0006954 244 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
regulation of cytokine production GO:0001817 266 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
alcohol metabolic process GO:0006066 116 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
renal system development GO:0072001 225 0.018
cofactor metabolic process GO:0051186 80 0.018
lipid localization GO:0010876 126 0.018
protein localization to organelle GO:0033365 185 0.018
cell type specific apoptotic process GO:0097285 268 0.018
nuclear division GO:0000280 158 0.018
cellular protein catabolic process GO:0044257 155 0.017
sphingolipid metabolic process GO:0006665 45 0.017
anion transmembrane transport GO:0098656 71 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
plasma membrane organization GO:0007009 90 0.017
hormone secretion GO:0046879 128 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
skeletal system development GO:0001501 356 0.017
positive regulation of cell death GO:0010942 224 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
apoptotic signaling pathway GO:0097190 306 0.017
regulation of protein localization GO:0032880 231 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
fatty acid metabolic process GO:0006631 121 0.017
regulation of anatomical structure size GO:0090066 178 0.017
negative regulation of molecular function GO:0044092 258 0.017
muscle cell differentiation GO:0042692 261 0.017
urogenital system development GO:0001655 261 0.017
carboxylic acid transport GO:0046942 100 0.017
mapk cascade GO:0000165 281 0.017
calcium ion transport GO:0006816 159 0.017
regulation of transmembrane transport GO:0034762 128 0.017
organelle localization GO:0051640 179 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
protein localization to membrane GO:0072657 108 0.016
response to acid chemical GO:0001101 111 0.016
axonogenesis GO:0007409 274 0.016
sodium ion transport GO:0006814 73 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
regulation of homeostatic process GO:0032844 182 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
amide transport GO:0042886 138 0.016
amino acid transport GO:0006865 61 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
cellular response to lipid GO:0071396 145 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
regulation of cellular component size GO:0032535 121 0.016
germ cell development GO:0007281 185 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
response to organic cyclic compound GO:0014070 198 0.016
dna metabolic process GO:0006259 303 0.015
innate immune response GO:0045087 157 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
sequestering of metal ion GO:0051238 19 0.015
positive regulation of secretion GO:0051047 130 0.015
organelle assembly GO:0070925 177 0.015
exocytosis GO:0006887 121 0.015
forebrain development GO:0030900 302 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
metal ion homeostasis GO:0055065 189 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
regulation of neuron differentiation GO:0045664 281 0.015
regulation of actin filament based process GO:0032970 99 0.015
blood vessel morphogenesis GO:0048514 285 0.015
membrane lipid biosynthetic process GO:0046467 32 0.015
regulation of mapk cascade GO:0043408 248 0.015
calcium ion homeostasis GO:0055074 127 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
retrograde transport endosome to golgi GO:0042147 2 0.015
steroid metabolic process GO:0008202 119 0.015
synaptic transmission GO:0007268 329 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
cellular alcohol metabolic process GO:0044107 3 0.015
dephosphorylation GO:0016311 129 0.015
lymphocyte differentiation GO:0030098 242 0.014
circulatory system process GO:0003013 197 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
gtp metabolic process GO:0046039 144 0.014
response to inorganic substance GO:0010035 96 0.014
regulation of kinase activity GO:0043549 249 0.014
membrane lipid metabolic process GO:0006643 53 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
positive regulation of gtp catabolic process GO:0033126 85 0.014
rhodopsin mediated signaling pathway GO:0016056 4 0.014
camera type eye development GO:0043010 266 0.014
muscle tissue development GO:0060537 308 0.014
response to peptide hormone GO:0043434 127 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
chemotaxis GO:0006935 247 0.014
response to peptide GO:1901652 136 0.014
positive regulation of necrotic cell death GO:0010940 1 0.014
phospholipid metabolic process GO:0006644 87 0.014
leukocyte mediated immunity GO:0002443 174 0.014
ensheathment of neurons GO:0007272 76 0.014
cell cell junction organization GO:0045216 72 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
regulation of t cell activation GO:0050863 170 0.014
lipid transport GO:0006869 98 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
positive regulation of protein modification process GO:0031401 299 0.014
endocytosis GO:0006897 168 0.014
cellular protein complex assembly GO:0043623 116 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
cell activation involved in immune response GO:0002263 126 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
mitochondrion distribution GO:0048311 4 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
regulation of body fluid levels GO:0050878 162 0.013
negative regulation of organelle organization GO:0010639 90 0.013
carbohydrate homeostasis GO:0033500 128 0.013
monosaccharide transport GO:0015749 58 0.013
regulation of intracellular transport GO:0032386 159 0.013
angiogenesis GO:0001525 201 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
striated muscle tissue development GO:0014706 293 0.013
l amino acid transport GO:0015807 32 0.013
organelle fission GO:0048285 170 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
protein processing GO:0016485 163 0.013
response to nutrient levels GO:0031667 109 0.013
regulation of defense response GO:0031347 233 0.013
positive regulation of cell development GO:0010720 237 0.013
mitotic cell cycle GO:0000278 195 0.013
single organism cell adhesion GO:0098602 156 0.013
sphingolipid biosynthetic process GO:0030148 26 0.013
compound eye development GO:0048749 1 0.013
myelination GO:0042552 74 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
methylation GO:0032259 134 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
glycoprotein metabolic process GO:0009100 116 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
protein ubiquitination GO:0016567 171 0.013
ossification GO:0001503 216 0.013
positive regulation of nervous system development GO:0051962 221 0.013
sensory organ morphogenesis GO:0090596 242 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
organic hydroxy compound transport GO:0015850 93 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
gland development GO:0048732 330 0.013
skeletal muscle organ development GO:0060538 163 0.013
rac protein signal transduction GO:0016601 13 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
myosin filament assembly GO:0031034 2 0.013
fertilization GO:0009566 127 0.012
meiotic cell cycle GO:0051321 122 0.012
establishment of organelle localization GO:0051656 122 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
cell substrate adhesion GO:0031589 130 0.012
regulation of metal ion transport GO:0010959 106 0.012
protein localization to plasma membrane GO:0072659 57 0.012
positive regulation of organelle organization GO:0010638 128 0.012
positive regulation of cellular ph reduction GO:0032849 2 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
locomotory behavior GO:0007626 195 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
retina development in camera type eye GO:0060041 119 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of hormone secretion GO:0046883 88 0.012
positive regulation of cell motility GO:2000147 116 0.012
wound healing GO:0042060 157 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
establishment of vesicle localization GO:0051650 81 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
vesicle localization GO:0051648 86 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
regulation of peptide transport GO:0090087 91 0.012
vesicle organization GO:0016050 60 0.012
adaptive immune response GO:0002250 155 0.012
regulation of system process GO:0044057 200 0.012
response to lipopolysaccharide GO:0032496 128 0.012
rhythmic process GO:0048511 174 0.012
axon ensheathment GO:0008366 76 0.012
learning or memory GO:0007611 148 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
tissue homeostasis GO:0001894 115 0.012
peptide hormone secretion GO:0030072 109 0.012
regulation of protein catabolic process GO:0042176 108 0.012
vitamin d3 metabolic process GO:0070640 3 0.012
organic acid biosynthetic process GO:0016053 86 0.012
regulation of cell cycle GO:0051726 281 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
peptide secretion GO:0002790 114 0.012
defense response to other organism GO:0098542 197 0.012
cellular alcohol biosynthetic process GO:0044108 3 0.012
monosaccharide metabolic process GO:0005996 106 0.012
cellular response to acid chemical GO:0071229 68 0.011
lymphocyte proliferation GO:0046651 164 0.011
t cell differentiation GO:0030217 174 0.011
multicellular organism growth GO:0035264 161 0.011
positive regulation of cytokine production GO:0001819 174 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
response to insulin GO:0032868 100 0.011
positive regulation of transferase activity GO:0051347 167 0.011
leukocyte migration GO:0050900 124 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
sodium ion transmembrane transport GO:0035725 49 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
regulation of multi organism process GO:0043900 111 0.011
protein complex disassembly GO:0043241 40 0.011
mesodermal cell migration GO:0008078 4 0.011
cellularization GO:0007349 1 0.011
calcitriol biosynthetic process from calciol GO:0036378 3 0.011
leukocyte proliferation GO:0070661 172 0.011
oocyte construction GO:0007308 2 0.011
response to radiation GO:0009314 165 0.011
response to growth factor GO:0070848 198 0.011
glucose homeostasis GO:0042593 128 0.011
lipid modification GO:0030258 65 0.011
positive regulation of defense response GO:0031349 124 0.011
vitamin transmembrane transport GO:0035461 4 0.011
intracellular mrna localization GO:0008298 4 0.011
gonad development GO:0008406 141 0.011
hexose metabolic process GO:0019318 98 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
atp metabolic process GO:0046034 75 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
ameboidal type cell migration GO:0001667 128 0.011
lateral inhibition GO:0046331 1 0.011
cytokinetic process GO:0032506 2 0.011
gliogenesis GO:0042063 141 0.011
blood circulation GO:0008015 195 0.011
positive regulation of cell activation GO:0050867 158 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
stem cell differentiation GO:0048863 268 0.010
single organismal cell cell adhesion GO:0016337 131 0.010
cognition GO:0050890 149 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
negative regulation of protein modification process GO:0031400 163 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
coenzyme metabolic process GO:0006732 52 0.010
hexose transport GO:0008645 56 0.010
kidney development GO:0001822 213 0.010
protein maturation GO:0051604 176 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
cell junction maintenance GO:0034331 4 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
regulation of transferase activity GO:0051338 263 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
fat cell differentiation GO:0045444 160 0.010
mitochondrion organization GO:0007005 134 0.010
regulation of protein transport GO:0051223 163 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
tube formation GO:0035148 140 0.010
carbohydrate transport GO:0008643 62 0.010
cell division GO:0051301 120 0.010
regulation of protein kinase activity GO:0045859 232 0.010

Pls1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.024
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.016
sensory system disease DOID:0050155 0 0.015
bone disease DOID:0080001 0 0.015
connective tissue disease DOID:65 0 0.015
hematopoietic system disease DOID:74 0 0.014
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010