|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.644
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.483
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.405
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.349
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.285
|
Zebrafish Mouse Rat Worm Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.268
|
Zebrafish Mouse Rat Worm Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.264
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.263
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.245
|
Zebrafish Mouse Rat Worm Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.243
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.233
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.218
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.217
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.215
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.209
|
Zebrafish Mouse Rat Worm Fly |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.196
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.195
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.191
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.191
|
Zebrafish Mouse Rat Fly |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.187
|
Zebrafish Mouse Rat Worm Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.180
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.179
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.176
|
Rat |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.170
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.166
|
Zebrafish Mouse Rat Fly |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.163
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.159
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.153
|
Zebrafish Mouse Rat Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.151
|
Zebrafish Mouse Rat Worm Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.147
|
Zebrafish Mouse Rat Worm Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.145
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.142
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.132
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.131
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.129
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.120
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.115
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.114
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.114
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.113
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.110
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.108
|
|
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.106
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.103
|
Worm |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.100
|
Zebrafish Mouse Rat Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.099
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.098
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.095
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.094
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.093
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.090
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.090
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.090
|
Zebrafish Mouse Rat Worm Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.089
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.089
|
|
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.088
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.087
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.087
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.085
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.085
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.082
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.082
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.081
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.080
|
Rat |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.079
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.079
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.076
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.076
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.076
|
Zebrafish Mouse Rat Worm Fly |
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.076
|
Zebrafish Mouse Rat Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.075
|
Zebrafish Mouse Rat Worm Fly |
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.074
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.073
|
Rat |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.073
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.073
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.073
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.072
|
Rat |
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.071
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.071
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.070
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.070
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.070
|
Rat |
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.069
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.068
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.067
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.065
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.065
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.065
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.065
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.065
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.064
|
Rat |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.063
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.063
|
Rat |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.061
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.059
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.059
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.059
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.059
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.059
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.058
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.057
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.057
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.056
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.056
|
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
4 |
0.056
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.055
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.055
|
Zebrafish Mouse Rat Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.054
|
Zebrafish Mouse Rat Worm Fly |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.053
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.053
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.053
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.053
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.053
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.053
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.052
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.052
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.051
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.051
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.051
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.051
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.051
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.051
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.051
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.051
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.050
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.050
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.050
|
Rat |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.049
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.049
|
|
|
|
vacuole organization
|
GO:0007033 |
38 |
0.049
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.049
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.048
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.047
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.047
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.047
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.047
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.047
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.047
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.047
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.046
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.046
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.046
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.046
|
Zebrafish |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.046
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.045
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.045
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.045
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.045
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.045
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.045
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.045
|
Zebrafish Mouse Rat Worm Fly |
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.044
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.044
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.044
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.044
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.044
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.043
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.043
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.043
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.043
|
Human |
|
|
wound healing
|
GO:0042060 |
157 |
0.043
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.043
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.042
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.042
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.042
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.042
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.042
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.042
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.041
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.041
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.041
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.041
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.041
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.041
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.041
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.041
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.041
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.040
|
Rat |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.040
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.039
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.039
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.038
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.038
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.038
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.038
|
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.038
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.037
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.037
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.037
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.036
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.036
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.036
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.036
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.036
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.036
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.036
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.036
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.035
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.035
|
Mouse Rat |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.035
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
3 |
0.035
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.035
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.035
|
Zebrafish Mouse Rat Fly |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.035
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.035
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.034
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.034
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.034
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.034
|
|
|
|
osmosensory signaling pathway
|
GO:0007231 |
1 |
0.034
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.033
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.033
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.033
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.033
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.033
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.033
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.033
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.033
|
Zebrafish Mouse Rat Worm Fly |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.033
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.033
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.033
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.032
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.032
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.032
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.032
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.032
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.032
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.032
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.032
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.032
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.032
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.031
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.031
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.031
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.031
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.031
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.031
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.031
|
Zebrafish Mouse Rat Fly |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.031
|
|
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.030
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.030
|
Rat |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.029
|
Zebrafish Mouse Rat Fly |
|
|
response to peptide
|
GO:1901652 |
136 |
0.029
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.029
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.029
|
Zebrafish Mouse Rat Fly |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.029
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.029
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.028
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.028
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.028
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.028
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.027
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.027
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.027
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.027
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.027
|
Fly |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.027
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.027
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.027
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.027
|
|
|
|
inositol phosphate catabolic process
|
GO:0071545 |
4 |
0.027
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.027
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.027
|
Worm |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.026
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.026
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.026
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.026
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.026
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.026
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.026
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.026
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.026
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.026
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.026
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.026
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.026
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.025
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.025
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.025
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.025
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.025
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.025
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.025
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.025
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.025
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.025
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.025
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.024
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.024
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.024
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.024
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.024
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.024
|
Rat |
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.024
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.024
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.024
|
|
|
|
golgi localization
|
GO:0051645 |
4 |
0.024
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.024
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.024
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.023
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.023
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.023
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.023
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.023
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.023
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.023
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.023
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.023
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.023
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.023
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.023
|
|
|
|
intra golgi vesicle mediated transport
|
GO:0006891 |
1 |
0.022
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.022
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.022
|
Rat |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.022
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.022
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.022
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.022
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.022
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.022
|
Zebrafish Mouse Rat Worm Fly |
|
|
germline cell cycle switching mitotic to meiotic cell cycle
|
GO:0051729 |
1 |
0.022
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.022
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.022
|
Worm |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.022
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.022
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.022
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.022
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.021
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.021
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.021
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.021
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.021
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.021
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.021
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.021
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.021
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.021
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.021
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.021
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.020
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.020
|
Zebrafish Mouse Rat Fly |
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.020
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.020
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.020
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.020
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.020
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.020
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.020
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.020
|
Rat |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.020
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.020
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.020
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.020
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.020
|
|
|
|
mitochondrion transport along microtubule
|
GO:0047497 |
3 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.020
|
|
|
|
positive regulation of macroautophagy
|
GO:0016239 |
3 |
0.020
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.020
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.019
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.019
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.019
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.019
|
|
|
|
cellular response to osmotic stress
|
GO:0071470 |
7 |
0.019
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.019
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.019
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.019
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.019
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.019
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.019
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.019
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.019
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.019
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.019
|
|
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.019
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.019
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.018
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.018
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.018
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.018
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.018
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.018
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.018
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.018
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.018
|
|
|
|
cellular response to cadmium ion
|
GO:0071276 |
3 |
0.018
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.018
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.018
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.018
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.018
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.018
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.018
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.018
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.018
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.018
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.017
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.017
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.017
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.017
|
|
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.017
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.017
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.017
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.017
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.017
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.017
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.017
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.017
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.017
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.017
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.017
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.017
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.017
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.017
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.017
|
Rat |
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.017
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.017
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.017
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.017
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.017
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.017
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.017
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.017
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.016
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.016
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.016
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.016
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.016
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.016
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.016
|
|
|
|
establishment of mitochondrion localization
|
GO:0051654 |
4 |
0.016
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.016
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.016
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.016
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.016
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.016
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.016
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.016
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.016
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.016
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.016
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.016
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.016
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.016
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.016
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.016
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.016
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.016
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.016
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.016
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.016
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.016
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.016
|
|
|
|
positive regulation of macrophage derived foam cell differentiation
|
GO:0010744 |
4 |
0.016
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.016
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.015
|
Rat |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.015
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
21 |
0.015
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.015
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.015
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
4 |
0.015
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.015
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.015
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.015
|
|
|
|
organelle disassembly
|
GO:1903008 |
2 |
0.015
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.015
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.015
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.015
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.015
|
|
|
|
viral gene expression
|
GO:0019080 |
3 |
0.015
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.015
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
30 |
0.015
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.015
|
Mouse |
|
|
organic anion transport
|
GO:0015711 |
137 |
0.015
|
|
|
|
positive regulation of nfat protein import into nucleus
|
GO:0051533 |
1 |
0.015
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.015
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.015
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.015
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.014
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.014
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.014
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.014
|
|
|
|
vesicle transport along microtubule
|
GO:0047496 |
9 |
0.014
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.014
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.014
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.014
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.014
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.014
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.014
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.014
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.014
|
Mouse |
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.014
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.014
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.014
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.014
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.014
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.014
|
|
