Mus musculus

0 known processes

Mmp23

matrix metallopeptidase 23

(Aliases: MGC130334,MGC130335,CA-MMP)

Mmp23 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.074
oxidation reduction process GO:0055114 342 0.072
extracellular structure organization GO:0043062 148 0.071
Mouse
lung development GO:0030324 164 0.056
response to organonitrogen compound GO:0010243 246 0.052
Mouse
respiratory system development GO:0060541 190 0.051
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.051
respiratory tube development GO:0030323 167 0.048
activation of immune response GO:0002253 138 0.041
cellular amino acid metabolic process GO:0006520 103 0.041
regulation of system process GO:0044057 200 0.040
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.039
skin development GO:0043588 220 0.038
male gamete generation GO:0048232 285 0.036
regulation of hydrolase activity GO:0051336 246 0.036
cell adhesion GO:0007155 329 0.035
cellular response to organonitrogen compound GO:0071417 145 0.035
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.035
regulation of cell projection organization GO:0031344 206 0.034
fibril organization GO:0097435 2 0.034
response to growth factor GO:0070848 198 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
regulation of cell adhesion GO:0030155 154 0.032
response to inorganic substance GO:0010035 96 0.031
extracellular matrix organization GO:0030198 147 0.031
Mouse
regulation of hormone levels GO:0010817 211 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.030
bone development GO:0060348 120 0.029
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.028
positive regulation of hydrolase activity GO:0051345 148 0.027
cellular ketone metabolic process GO:0042180 84 0.027
fat cell differentiation GO:0045444 160 0.027
developmental maturation GO:0021700 193 0.026
innate immune response GO:0045087 157 0.026
protein maturation GO:0051604 176 0.026
cellular response to amino acid stimulus GO:0071230 29 0.026
Mouse
positive regulation of nervous system development GO:0051962 221 0.025
spermatogenesis GO:0007283 284 0.025
defense response to bacterium GO:0042742 119 0.025
Mouse
positive regulation of cell death GO:0010942 224 0.024
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.024
transmembrane transport GO:0055085 412 0.024
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.024
immune effector process GO:0002252 321 0.023
interspecies interaction between organisms GO:0044419 83 0.023
carbohydrate metabolic process GO:0005975 230 0.023
skeletal system development GO:0001501 356 0.023
Mouse
response to transforming growth factor beta GO:0071559 88 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
anatomical structure homeostasis GO:0060249 145 0.023
synaptic transmission GO:0007268 329 0.023
mitochondrion organization GO:0007005 134 0.022
protein processing GO:0016485 163 0.022
regulation of secretion GO:0051046 274 0.022
regulation of cytokine production GO:0001817 266 0.021
renal system development GO:0072001 225 0.021
carbohydrate homeostasis GO:0033500 128 0.020
ion transmembrane transport GO:0034220 361 0.020
positive regulation of apoptotic signaling pathway GO:2001235 95 0.020
homeostasis of number of cells GO:0048872 210 0.019
rho protein signal transduction GO:0007266 32 0.019
regulation of removal of superoxide radicals GO:2000121 4 0.019
protein hydroxylation GO:0018126 4 0.019
response to organic cyclic compound GO:0014070 198 0.019
striated muscle cell development GO:0055002 125 0.019
monocarboxylic acid metabolic process GO:0032787 191 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
insulin processing GO:0030070 2 0.019
biomineral tissue development GO:0031214 64 0.019
Mouse
cell type specific apoptotic process GO:0097285 268 0.019
striated muscle tissue development GO:0014706 293 0.019
positive regulation of apoptotic process GO:0043065 217 0.018
positive regulation of transferase activity GO:0051347 167 0.018
positive regulation of cell projection organization GO:0031346 95 0.018
monosaccharide metabolic process GO:0005996 106 0.018
positive regulation of organelle organization GO:0010638 128 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
nitrogen compound transport GO:0071705 271 0.018
Mouse
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.018
mesonephros development GO:0001823 97 0.018
negative regulation of phospholipase activity GO:0010519 4 0.018
hormone secretion GO:0046879 128 0.017
apoptotic signaling pathway GO:0097190 306 0.017
cellular response to acid chemical GO:0071229 68 0.017
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
regulation of cellular response to stress GO:0080135 159 0.017
Mouse
learning or memory GO:0007611 148 0.017
ossification GO:0001503 216 0.017
Mouse
bmp signaling pathway GO:0030509 93 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
tissue homeostasis GO:0001894 115 0.016
superoxide metabolic process GO:0006801 27 0.016
elastic fiber assembly GO:0048251 4 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
epithelial cell proliferation GO:0050673 174 0.016
urogenital system development GO:0001655 261 0.016
leukocyte differentiation GO:0002521 342 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
response to acid chemical GO:0001101 111 0.016
Mouse
phagolysosome assembly GO:0001845 3 0.015
response to amino acid GO:0043200 37 0.015
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.015
gland development GO:0048732 330 0.015
response to bmp GO:0071772 14 0.015
digestive system development GO:0055123 200 0.015
antibacterial peptide secretion GO:0002779 1 0.015
Mouse
epidermis development GO:0008544 187 0.015
antibacterial peptide production GO:0002778 2 0.015
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.015
defense response to other organism GO:0098542 197 0.015
Mouse
glucose homeostasis GO:0042593 128 0.015
regulation of interleukin 8 production GO:0032677 3 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
regulation of cell migration GO:0030334 219 0.014
Mouse
multicellular organismal signaling GO:0035637 91 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
physiological cardiac muscle hypertrophy GO:0003301 3 0.014
hormone metabolic process GO:0042445 86 0.014
action potential GO:0001508 78 0.014
muscle cell development GO:0055001 133 0.014
mitochondrion distribution GO:0048311 4 0.014
negative regulation of ossification GO:0030279 49 0.014
peptide secretion GO:0002790 114 0.014
Mouse
positive regulation of protein modification process GO:0031401 299 0.014
sensory organ morphogenesis GO:0090596 242 0.014
regulation of cell projection assembly GO:0060491 38 0.014
acetylcholine transport GO:0015870 2 0.014
response to peptide GO:1901652 136 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
antimicrobial peptide secretion GO:0002776 1 0.014
Mouse
stem cell differentiation GO:0048863 268 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
amide transport GO:0042886 138 0.013
Mouse
negative regulation of phosphorylation GO:0042326 166 0.013
protein oligomerization GO:0051259 67 0.013
muscle tissue development GO:0060537 308 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.013
cell recognition GO:0008037 83 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
response to peptide hormone GO:0043434 127 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
peptidyl amino acid modification GO:0018193 336 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
regulation of secretion by cell GO:1903530 249 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
sensory perception GO:0007600 245 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
negative regulation of immune system process GO:0002683 209 0.013
Mouse
multicellular organismal response to stress GO:0033555 62 0.012
wound healing GO:0042060 157 0.012
multicellular organism growth GO:0035264 161 0.012
protein polymerization GO:0051258 57 0.012
insulin metabolic process GO:1901142 3 0.012
lateral inhibition GO:0046331 1 0.012
positive regulation of secretion GO:0051047 130 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
amine metabolic process GO:0009308 45 0.012
cellular response to inorganic substance GO:0071241 37 0.012
regulation of protein localization GO:0032880 231 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
head morphogenesis GO:0060323 34 0.012
tendon formation GO:0035992 4 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.011
response to radiation GO:0009314 165 0.011
regulation of membrane potential GO:0042391 192 0.011
divalent metal ion transport GO:0070838 172 0.011
tendon cell differentiation GO:0035990 4 0.011
sulfur compound metabolic process GO:0006790 100 0.011
b cell activation GO:0042113 161 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of homeostatic process GO:0032844 182 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of response to wounding GO:1903034 189 0.011
organelle assembly GO:0070925 177 0.011
response to oxidative stress GO:0006979 123 0.011
Mouse
positive regulation of cell development GO:0010720 237 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
negative regulation of cell adhesion GO:0007162 45 0.011
cellular response to external stimulus GO:0071496 88 0.011
positive regulation of proteolysis GO:0045862 85 0.011
multi multicellular organism process GO:0044706 109 0.011
regulation of mapk cascade GO:0043408 248 0.011
cognition GO:0050890 149 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
regulation of proteolysis GO:0030162 164 0.011
interleukin 8 production GO:0032637 4 0.011
cell growth GO:0016049 130 0.011
regulation of norepinephrine secretion GO:0014061 2 0.010
peptide metabolic process GO:0006518 46 0.010
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
Mouse
cellular response to oxidative stress GO:0034599 76 0.010
Mouse
blood circulation GO:0008015 195 0.010
regulation of ossification GO:0030278 112 0.010
regulation of neuron projection development GO:0010975 169 0.010
mitotic cell cycle GO:0000278 195 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
Mouse
stem cell development GO:0048864 219 0.010
glycoprotein metabolic process GO:0009100 116 0.010
response to reactive oxygen species GO:0000302 56 0.010
cytokine production GO:0001816 319 0.010
muscle cell differentiation GO:0042692 261 0.010
molting cycle GO:0042303 90 0.010
heterocycle catabolic process GO:0046700 280 0.010
negative regulation of molecular function GO:0044092 258 0.010
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.010
forebrain development GO:0030900 302 0.010
lymphocyte differentiation GO:0030098 242 0.010
glucose metabolic process GO:0006006 92 0.010
regulation of actin filament polymerization GO:0030833 38 0.010
organic cyclic compound catabolic process GO:1901361 295 0.010
regulation of kinase activity GO:0043549 249 0.010
negative regulation of lipoprotein lipase activity GO:0051005 1 0.010
protein heterooligomerization GO:0051291 14 0.010

Mmp23 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.120
disease of anatomical entity DOID:7 0 0.120
eye and adnexa disease DOID:1492 0 0.120
nervous system disease DOID:863 0 0.120
eye disease DOID:5614 0 0.103
retinal disease DOID:5679 0 0.083
retinal degeneration DOID:8466 0 0.083
musculoskeletal system disease DOID:17 0 0.074
connective tissue disease DOID:65 0 0.045
glaucoma DOID:1686 0 0.033
bone development disease DOID:0080006 0 0.017
bone disease DOID:0080001 0 0.017
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
muscular dystrophy DOID:9884 0 0.016
muscle tissue disease DOID:66 0 0.016