Mus musculus

41 known processes

Abi2

abl-interactor 2

(Aliases: C130078H13,8430425M24Rik,AI839867,MGC90855,MGC90836)

Abi2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.068
cilium morphogenesis GO:0060271 102 0.063
amine metabolic process GO:0009308 45 0.059
regulation of transferase activity GO:0051338 263 0.058
Mouse Fly
transmembrane transport GO:0055085 412 0.056
cation transmembrane transport GO:0098655 266 0.056
cation transport GO:0006812 399 0.055
regulation of cellular amine metabolic process GO:0033238 20 0.052
regulation of organelle organization GO:0033043 289 0.045
Human
intracellular protein transport GO:0006886 204 0.045
inorganic cation transmembrane transport GO:0098662 207 0.043
regulation of neuron differentiation GO:0045664 281 0.043
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.042
cilium assembly GO:0042384 81 0.042
response to organonitrogen compound GO:0010243 246 0.041
cellular amine metabolic process GO:0044106 44 0.041
ion transmembrane transport GO:0034220 361 0.040
protein modification by small protein conjugation or removal GO:0070647 207 0.039
organelle assembly GO:0070925 177 0.039
multi multicellular organism process GO:0044706 109 0.038
Worm
inorganic ion transmembrane transport GO:0098660 234 0.038
compound eye development GO:0048749 1 0.038
gonad development GO:0008406 141 0.037
Worm
positive regulation of protein modification process GO:0031401 299 0.036
Mouse Fly
regulation of kinase activity GO:0043549 249 0.035
Mouse Fly
male gamete generation GO:0048232 285 0.035
ribonucleoside metabolic process GO:0009119 245 0.034
skeletal system development GO:0001501 356 0.034
fat cell differentiation GO:0045444 160 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
Mouse Fly
neuronal action potential GO:0019228 54 0.034
cell type specific apoptotic process GO:0097285 268 0.033
stem cell differentiation GO:0048863 268 0.032
t cell activation GO:0042110 289 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
nucleoside metabolic process GO:0009116 246 0.032
cellular response to organonitrogen compound GO:0071417 145 0.031
learning or memory GO:0007611 148 0.031
cellular amino acid metabolic process GO:0006520 103 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
cellular ketone metabolic process GO:0042180 84 0.030
action potential GO:0001508 78 0.030
nitrogen compound transport GO:0071705 271 0.029
positive regulation of protein kinase activity GO:0045860 144 0.029
Mouse Fly
protein ubiquitination GO:0016567 171 0.028
stem cell development GO:0048864 219 0.028
divalent metal ion transport GO:0070838 172 0.028
cell division GO:0051301 120 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
microtubule based process GO:0007017 236 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
cellular chemical homeostasis GO:0055082 215 0.027
negative regulation of nervous system development GO:0051961 156 0.026
divalent inorganic cation transport GO:0072511 178 0.026
kidney development GO:0001822 213 0.026
positive regulation of transferase activity GO:0051347 167 0.025
Mouse Fly
spermatogenesis GO:0007283 284 0.025
cellular ion homeostasis GO:0006873 165 0.025
sensory perception GO:0007600 245 0.025
regulation of establishment of protein localization GO:0070201 181 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
endocytosis GO:0006897 168 0.024
Worm Fly
negative regulation of cell development GO:0010721 169 0.024
multicellular organismal signaling GO:0035637 91 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.023
regulation of hydrolase activity GO:0051336 246 0.023
germ cell development GO:0007281 185 0.023
t cell differentiation GO:0030217 174 0.023
lymphocyte differentiation GO:0030098 242 0.023
positive regulation of cell death GO:0010942 224 0.023
cognition GO:0050890 149 0.023
response to organic cyclic compound GO:0014070 198 0.022
regulation of vesicle mediated transport GO:0060627 139 0.022
Worm
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
translation GO:0006412 93 0.022
stem cell maintenance GO:0019827 130 0.022
cellular homeostasis GO:0019725 240 0.022
mitotic cell cycle GO:0000278 195 0.022
spermatid differentiation GO:0048515 115 0.022
organic cyclic compound catabolic process GO:1901361 295 0.021
regulation of membrane potential GO:0042391 192 0.021
gonad morphogenesis GO:0035262 1 0.021
regulation of protein kinase activity GO:0045859 232 0.021
Mouse Fly
maintenance of location GO:0051235 89 0.021
ossification GO:0001503 216 0.021
neural tube development GO:0021915 160 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
cell fate commitment GO:0045165 210 0.020
macromolecule catabolic process GO:0009057 281 0.020
chromatin organization GO:0006325 206 0.020
regulation of ion transport GO:0043269 215 0.020
synapse assembly GO:0007416 56 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
peptidyl amino acid modification GO:0018193 336 0.020
Human Mouse
protein localization to organelle GO:0033365 185 0.019
mapk cascade GO:0000165 281 0.019
cellular lipid metabolic process GO:0044255 323 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
developmental maturation GO:0021700 193 0.019
forebrain development GO:0030900 302 0.019
positive regulation of kinase activity GO:0033674 155 0.019
Mouse Fly
regulation of homeostatic process GO:0032844 182 0.019
protein catabolic process GO:0030163 221 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
camera type eye development GO:0043010 266 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
calcium ion transport GO:0006816 159 0.019
development of primary sexual characteristics GO:0045137 143 0.019
Worm
cation homeostasis GO:0055080 212 0.019
oxidation reduction process GO:0055114 342 0.019
mesoderm development GO:0007498 100 0.019
negative regulation of molecular function GO:0044092 258 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
Human
ribonucleoside catabolic process GO:0042454 206 0.019
nucleotide metabolic process GO:0009117 332 0.019
negative regulation of synapse assembly GO:0051964 3 0.019
carbohydrate homeostasis GO:0033500 128 0.019
purine containing compound metabolic process GO:0072521 311 0.019
connective tissue development GO:0061448 179 0.019
midgut development GO:0007494 4 0.019
glycoprotein metabolic process GO:0009100 116 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
sensory organ morphogenesis GO:0090596 242 0.018
leukocyte differentiation GO:0002521 342 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
nucleotide catabolic process GO:0009166 217 0.018
organic acid biosynthetic process GO:0016053 86 0.018
sulfur compound metabolic process GO:0006790 100 0.018
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
neuron death GO:0070997 154 0.018
regulation of intracellular transport GO:0032386 159 0.018
aromatic compound catabolic process GO:0019439 286 0.018
carbohydrate metabolic process GO:0005975 230 0.018
positive regulation of cellular component biogenesis GO:0044089 94 0.017
Human
glycosyl compound catabolic process GO:1901658 206 0.017
epithelial cell development GO:0002064 159 0.017
glucose homeostasis GO:0042593 128 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
immune effector process GO:0002252 321 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
g1 s transition of mitotic cell cycle GO:0000082 57 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
regulation of translation GO:0006417 71 0.017
nucleoside catabolic process GO:0009164 206 0.017
regulation of hormone levels GO:0010817 211 0.017
regulation of cell projection organization GO:0031344 206 0.017
blood vessel morphogenesis GO:0048514 285 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
heterocycle catabolic process GO:0046700 280 0.016
nuclear import GO:0051170 95 0.016
gland development GO:0048732 330 0.016
transmission of nerve impulse GO:0019226 76 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
sensory perception of sound GO:0007605 97 0.016
adult behavior GO:0030534 135 0.016
amide transport GO:0042886 138 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
response to lipopolysaccharide GO:0032496 128 0.016
placenta development GO:0001890 140 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
regulation of protein localization GO:0032880 231 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
organophosphate catabolic process GO:0046434 232 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
ribonucleotide catabolic process GO:0009261 208 0.015
locomotory behavior GO:0007626 195 0.015
dna metabolic process GO:0006259 303 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
spermatid development GO:0007286 108 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
metal ion homeostasis GO:0055065 189 0.015
muscle cell differentiation GO:0042692 261 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
Human
regulation of mapk cascade GO:0043408 248 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
single organism nuclear import GO:1902593 95 0.015
positive regulation of organelle organization GO:0010638 128 0.015
Human
regulation of cell migration GO:0030334 219 0.015
multi organism behavior GO:0051705 62 0.015
Worm
synaptic transmission GO:0007268 329 0.015
mitotic cell cycle process GO:1903047 159 0.015
cellular response to lipid GO:0071396 145 0.015
regionalization GO:0003002 337 0.015
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.015
microtubule based movement GO:0007018 84 0.015
response to nutrient levels GO:0031667 109 0.015
photoreceptor cell differentiation GO:0046530 52 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.014
aminoglycan metabolic process GO:0006022 34 0.014
regulation of transmembrane transport GO:0034762 128 0.014
membrane organization GO:0061024 245 0.014
Worm
regulation of secretion by cell GO:1903530 249 0.014
rna processing GO:0006396 105 0.014
regulation of secretion GO:0051046 274 0.014
regulation of cell motility GO:2000145 236 0.014
gastrulation GO:0007369 116 0.014
axon ensheathment GO:0008366 76 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
protein targeting GO:0006605 143 0.014
neuroblast differentiation GO:0014016 2 0.014
transition metal ion transport GO:0000041 38 0.014
positive regulation of nervous system development GO:0051962 221 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
rhodopsin mediated signaling pathway GO:0016056 4 0.014
cytoplasmic transport GO:0016482 234 0.014
mucopolysaccharide metabolic process GO:1903510 25 0.014
cellular response to external stimulus GO:0071496 88 0.014
response to extracellular stimulus GO:0009991 127 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
telencephalon development GO:0021537 186 0.014
smoothened signaling pathway GO:0007224 105 0.014
fatty acid metabolic process GO:0006631 121 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
regulation of actin filament based process GO:0032970 99 0.014
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
regulation of phospholipase c activity GO:1900274 3 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
organic anion transport GO:0015711 137 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
muscle tissue development GO:0060537 308 0.013
regulation of map kinase activity GO:0043405 120 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
protein maturation GO:0051604 176 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
apoptotic signaling pathway GO:0097190 306 0.013
regulation of cell cycle GO:0051726 281 0.013
protein import GO:0017038 101 0.013
negative regulation of neuron differentiation GO:0045665 101 0.013
ras protein signal transduction GO:0007265 77 0.013
Human
calcium ion transmembrane transport GO:0070588 85 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
homeostasis of number of cells GO:0048872 210 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
ear development GO:0043583 200 0.013
small molecule biosynthetic process GO:0044283 132 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of system process GO:0044057 200 0.013
meiotic nuclear division GO:0007126 115 0.013
eye photoreceptor cell differentiation GO:0001754 41 0.013
protein autophosphorylation GO:0046777 61 0.013
regulation of protein catabolic process GO:0042176 108 0.013
lipid biosynthetic process GO:0008610 179 0.013
striated muscle tissue development GO:0014706 293 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
renal system development GO:0072001 225 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
peptidyl serine modification GO:0018209 83 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
photoreceptor cell development GO:0042461 40 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of protein stability GO:0031647 52 0.012
synapse organization GO:0050808 125 0.012
Fly
digestive tract development GO:0048565 190 0.012
macromolecule methylation GO:0043414 120 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
adult locomotory behavior GO:0008344 91 0.012
hormone secretion GO:0046879 128 0.012
glycosylation GO:0070085 62 0.012
protein acylation GO:0043543 64 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
t cell differentiation in thymus GO:0033077 77 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
leukocyte mediated immunity GO:0002443 174 0.012
positive regulation of phospholipase activity GO:0010518 3 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
endomembrane system organization GO:0010256 147 0.012
Fly
monocarboxylic acid metabolic process GO:0032787 191 0.012
response to drug GO:0042493 75 0.012
epithelial tube formation GO:0072175 130 0.012
regulation of rna splicing GO:0043484 37 0.012
response to peptide hormone GO:0043434 127 0.012
carbohydrate transport GO:0008643 62 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
reproductive behavior GO:0019098 32 0.012
Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
regulation of binding GO:0051098 111 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
purine containing compound catabolic process GO:0072523 213 0.012
regulation of proteolysis GO:0030162 164 0.012
female gamete generation GO:0007292 74 0.012
monosaccharide transport GO:0015749 58 0.012
multicellular organism growth GO:0035264 161 0.012
lateral inhibition GO:0046331 1 0.012
actin cytoskeleton organization GO:0030036 220 0.012
Human Fly
chemotaxis GO:0006935 247 0.011
Fly
olfactory learning GO:0008355 2 0.011
regulation of protein targeting GO:1903533 61 0.011
inflammatory response GO:0006954 244 0.011
skeletal system morphogenesis GO:0048705 203 0.011
glucose transport GO:0015758 56 0.011
neuron apoptotic process GO:0051402 142 0.011
fatty acid biosynthetic process GO:0006633 41 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
peptide transport GO:0015833 133 0.011
negative regulation of protein modification process GO:0031400 163 0.011
regulation of cell activation GO:0050865 289 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
protein glycosylation GO:0006486 55 0.011
hexose transport GO:0008645 56 0.011
actin filament based movement GO:0030048 23 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
intracellular mrna localization GO:0008298 4 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.011
digestive system development GO:0055123 200 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
epidermis development GO:0008544 187 0.011
retina development in camera type eye GO:0060041 119 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
Mouse
protein processing GO:0016485 163 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
axon guidance GO:0007411 141 0.011
Fly
negative regulation of growth GO:0045926 99 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
organelle localization GO:0051640 179 0.011
rna splicing via transesterification reactions GO:0000375 43 0.010
nuclear transport GO:0051169 139 0.010
fertilization GO:0009566 127 0.010
anatomical structure homeostasis GO:0060249 145 0.010
peptidyl lysine modification GO:0018205 77 0.010
tube formation GO:0035148 140 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
negative regulation of immune system process GO:0002683 209 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
ensheathment of neurons GO:0007272 76 0.010
somatic cell dna recombination GO:0016444 51 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
methylation GO:0032259 134 0.010
muscle system process GO:0003012 141 0.010
regulation of neuron death GO:1901214 134 0.010
organelle fission GO:0048285 170 0.010
neural tube formation GO:0001841 108 0.010
negative regulation of neuron death GO:1901215 98 0.010
atp metabolic process GO:0046034 75 0.010
establishment of organelle localization GO:0051656 122 0.010
cytoskeleton dependent intracellular transport GO:0030705 50 0.010
response to insulin GO:0032868 100 0.010
learning GO:0007612 98 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
regulation of cellular catabolic process GO:0031329 242 0.010

Abi2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
large intestine cancer DOID:5672 0 0.013
colon cancer DOID:219 0 0.013
gastrointestinal system cancer DOID:3119 0 0.013
intestinal cancer DOID:10155 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
colorectal cancer DOID:9256 0 0.013
central nervous system disease DOID:331 0 0.012