Mus musculus

104 known processes

Abi1

abl-interactor 1

(Aliases: MGC6064,Ssh3bp1,NAP1,E3B1)

Abi1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament organization GO:0007015 113 0.964
actin filament polymerization GO:0030041 44 0.961
rac protein signal transduction GO:0016601 13 0.941
actin cytoskeleton organization GO:0030036 220 0.935
Fly
cell adhesion GO:0007155 329 0.911
Fly
regulation of cytoskeleton organization GO:0051493 122 0.875
axon guidance GO:0007411 141 0.868
Fly
axonogenesis GO:0007409 274 0.865
Fly
protein polymerization GO:0051258 57 0.864
regulation of actin cytoskeleton organization GO:0032956 84 0.858
regulation of actin filament polymerization GO:0030833 38 0.843
regulation of actin polymerization or depolymerization GO:0008064 45 0.841
regulation of actin filament length GO:0030832 45 0.832
regulation of cellular component biogenesis GO:0044087 181 0.801
endocytosis GO:0006897 168 0.800
Worm Fly
regulation of actin filament based process GO:0032970 99 0.748
regulation of protein complex assembly GO:0043254 83 0.746
synaptic transmission GO:0007268 329 0.734
actin polymerization or depolymerization GO:0008154 54 0.731
synapse organization GO:0050808 125 0.688
Fly
positive regulation of cellular component biogenesis GO:0044089 94 0.665
regulation of hydrolase activity GO:0051336 246 0.642
regulation of organelle organization GO:0033043 289 0.617
cellular protein complex assembly GO:0043623 116 0.597
regulation of cell shape GO:0008360 39 0.570
Fly
single organism cell adhesion GO:0098602 156 0.569
organophosphate catabolic process GO:0046434 232 0.550
positive regulation of actin filament polymerization GO:0030838 26 0.548
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.539
membrane organization GO:0061024 245 0.537
Worm
neuron projection guidance GO:0097485 141 0.527
Fly
regulation of cellular component size GO:0032535 121 0.520
membrane tubulation GO:0097320 4 0.512
single organismal cell cell adhesion GO:0016337 131 0.508
ras protein signal transduction GO:0007265 77 0.507
positive regulation of cell projection organization GO:0031346 95 0.473
carbohydrate derivative catabolic process GO:1901136 231 0.464
lymphocyte differentiation GO:0030098 242 0.449
chemotaxis GO:0006935 247 0.441
Fly
hematopoietic progenitor cell differentiation GO:0002244 143 0.439
b cell homeostasis GO:0001782 34 0.412
negative regulation of cytoskeleton organization GO:0051494 36 0.386
actin filament bundle assembly GO:0051017 40 0.377
regulation of ion transport GO:0043269 215 0.371
organic cyclic compound catabolic process GO:1901361 295 0.368
establishment of organelle localization GO:0051656 122 0.368
t cell activation GO:0042110 289 0.354
reproductive behavior GO:0019098 32 0.349
Worm
regulation of anatomical structure size GO:0090066 178 0.349
regulation of membrane potential GO:0042391 192 0.335
regulation of cell projection organization GO:0031344 206 0.331
cation transport GO:0006812 399 0.324
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.323
multi multicellular organism process GO:0044706 109 0.314
Worm
multicellular organismal reproductive behavior GO:0033057 23 0.314
Worm
establishment of vesicle localization GO:0051650 81 0.303
regulation of protein localization GO:0032880 231 0.298
purine nucleoside metabolic process GO:0042278 241 0.286
negative regulation of cellular component organization GO:0051129 194 0.285
t cell differentiation GO:0030217 174 0.284
dephosphorylation GO:0016311 129 0.281
regulation of cellular ketone metabolic process GO:0010565 66 0.273
nucleotide catabolic process GO:0009166 217 0.273
regulation of system process GO:0044057 200 0.247
lamellipodium organization GO:0097581 29 0.244
positive regulation of hydrolase activity GO:0051345 148 0.243
establishment or maintenance of cell polarity GO:0007163 86 0.227
purine containing compound catabolic process GO:0072523 213 0.221
positive regulation of nervous system development GO:0051962 221 0.218
establishment of synaptic vesicle localization GO:0097480 57 0.213
negative regulation of protein metabolic process GO:0051248 282 0.199
dendrite development GO:0016358 115 0.199
Mouse
regulation of neuron projection development GO:0010975 169 0.198
ribonucleoside metabolic process GO:0009119 245 0.196
regulation of vesicle mediated transport GO:0060627 139 0.195
Worm
small gtpase mediated signal transduction GO:0007264 97 0.191
synaptic vesicle localization GO:0097479 59 0.187
vesicle localization GO:0051648 86 0.182
cell aging GO:0007569 35 0.178
gtp catabolic process GO:0006184 143 0.178
positive regulation of cytoskeleton organization GO:0051495 49 0.173
leukocyte differentiation GO:0002521 342 0.172
calcium ion transport GO:0006816 159 0.164
ribonucleotide catabolic process GO:0009261 208 0.163
multi organism reproductive behavior GO:0044705 29 0.163
Worm
female gamete generation GO:0007292 74 0.161
phagocytosis GO:0006909 66 0.155
Worm Fly
cellular nitrogen compound catabolic process GO:0044270 280 0.154
regulation of cell adhesion GO:0030155 154 0.152
nucleoside metabolic process GO:0009116 246 0.149
aromatic compound catabolic process GO:0019439 286 0.146
positive regulation of organelle organization GO:0010638 128 0.144
regulation of purine nucleotide metabolic process GO:1900542 169 0.144
meiotic cell cycle GO:0051321 122 0.143
motor neuron axon guidance GO:0008045 26 0.142
positive regulation of nucleotide catabolic process GO:0030813 88 0.141
nucleoside triphosphate catabolic process GO:0009143 205 0.141
glycosyl compound metabolic process GO:1901657 246 0.139
body morphogenesis GO:0010171 45 0.137
Worm
membrane fusion GO:0061025 38 0.137
organelle localization GO:0051640 179 0.135
positive regulation of protein complex assembly GO:0031334 45 0.134
regulation of cellular catabolic process GO:0031329 242 0.133
ribose phosphate metabolic process GO:0019693 291 0.133
regulation of cell cycle GO:0051726 281 0.132
organic hydroxy compound metabolic process GO:1901615 203 0.131
purine containing compound metabolic process GO:0072521 311 0.130
regulation of cell projection assembly GO:0060491 38 0.130
gliogenesis GO:0042063 141 0.129
germ cell development GO:0007281 185 0.128
neurotransmitter transport GO:0006836 76 0.127
actin filament depolymerization GO:0030042 15 0.126
leukocyte homeostasis GO:0001776 79 0.126
ribonucleoside triphosphate catabolic process GO:0009203 199 0.124
neuronal action potential GO:0019228 54 0.122
protein localization to endosome GO:0036010 2 0.122
leukocyte proliferation GO:0070661 172 0.121
regulation of cell activation GO:0050865 289 0.120
negative regulation of actin filament depolymerization GO:0030835 9 0.119
transmembrane transport GO:0055085 412 0.119
positive regulation of cell death GO:0010942 224 0.116
axon ensheathment GO:0008366 76 0.116
regulation of lamellipodium assembly GO:0010591 3 0.115
regulation of t cell activation GO:0050863 170 0.114
glial cell differentiation GO:0010001 131 0.112
positive regulation of cell development GO:0010720 237 0.108
t cell proliferation GO:0042098 120 0.108
guanosine containing compound metabolic process GO:1901068 144 0.105
ion transmembrane transport GO:0034220 361 0.104
substrate dependent cell migration cell extension GO:0006930 4 0.104
action potential GO:0001508 78 0.103
posttranscriptional regulation of gene expression GO:0010608 155 0.103
gtp metabolic process GO:0046039 144 0.101
regulation of t cell proliferation GO:0042129 92 0.101
regulation of cellular amine metabolic process GO:0033238 20 0.100
cell type specific apoptotic process GO:0097285 268 0.095
regulation of synaptic vesicle transport GO:1902803 13 0.095
transmission of nerve impulse GO:0019226 76 0.094
glycosyl compound catabolic process GO:1901658 206 0.093
nucleoside triphosphate metabolic process GO:0009141 230 0.093
synapse assembly GO:0007416 56 0.093
positive regulation of cell adhesion GO:0045785 80 0.093
purine nucleotide metabolic process GO:0006163 302 0.093
regionalization GO:0003002 337 0.092
male gamete generation GO:0048232 285 0.092
neuron migration GO:0001764 122 0.090
Worm
regulation of neurotransmitter secretion GO:0046928 29 0.089
leukocyte migration GO:0050900 124 0.089
protein localization to membrane GO:0072657 108 0.088
protein localization to organelle GO:0033365 185 0.088
nucleoside phosphate metabolic process GO:0006753 338 0.087
negative regulation of synapse assembly GO:0051964 3 0.086
regulation of lymphocyte differentiation GO:0045619 107 0.086
regulation of nucleotide metabolic process GO:0006140 169 0.086
purine nucleoside triphosphate metabolic process GO:0009144 226 0.085
macromolecule catabolic process GO:0009057 281 0.084
development of primary sexual characteristics GO:0045137 143 0.084
Worm
developmental maturation GO:0021700 193 0.084
negative regulation of phosphate metabolic process GO:0045936 184 0.083
regulation of secretion by cell GO:1903530 249 0.083
regulation of homeostatic process GO:0032844 182 0.083
regulation of t cell differentiation GO:0045580 83 0.083
divalent metal ion transport GO:0070838 172 0.082
purine ribonucleotide metabolic process GO:0009150 290 0.081
nuclear division GO:0000280 158 0.081
cellularization GO:0007349 1 0.081
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.080
organelle assembly GO:0070925 177 0.079
myeloid cell differentiation GO:0030099 233 0.079
embryonic epithelial tube formation GO:0001838 130 0.079
positive regulation of lamellipodium assembly GO:0010592 2 0.078
lymphocyte proliferation GO:0046651 164 0.078
response to organonitrogen compound GO:0010243 246 0.077
myelination GO:0042552 74 0.077
lymphocyte homeostasis GO:0002260 64 0.075
regulation of ion transmembrane transporter activity GO:0032412 54 0.074
regulation of neurotransmitter levels GO:0001505 87 0.074
regulation of synaptic vesicle exocytosis GO:2000300 11 0.074
spermatogenesis GO:0007283 284 0.073
heterocycle catabolic process GO:0046700 280 0.073
regulation of cellular amino acid metabolic process GO:0006521 5 0.073
cell division GO:0051301 120 0.073
ensheathment of neurons GO:0007272 76 0.072
synaptic growth at neuromuscular junction GO:0051124 6 0.072
negative regulation of protein complex disassembly GO:0043242 22 0.071
microtubule based movement GO:0007018 84 0.071
regulation of lymphocyte activation GO:0051249 240 0.071
regulation of wnt signaling pathway GO:0030111 123 0.071
actin filament based movement GO:0030048 23 0.070
cellular metal ion homeostasis GO:0006875 151 0.070
purine ribonucleoside catabolic process GO:0046130 205 0.069
regulation of glutamate receptor signaling pathway GO:1900449 16 0.068
regulation of neuron differentiation GO:0045664 281 0.067
regulation of cell motility GO:2000145 236 0.066
endomembrane system organization GO:0010256 147 0.066
Fly
regulation of secretion GO:0051046 274 0.066
mesodermal cell migration GO:0008078 4 0.065
neurotransmitter secretion GO:0007269 62 0.065
glial cell development GO:0021782 54 0.065
glutamate receptor signaling pathway GO:0007215 35 0.065
regulation of leukocyte proliferation GO:0070663 121 0.065
regulation of cytokine production GO:0001817 266 0.065
regulation of synapse assembly GO:0051963 29 0.065
insulin secretion GO:0030073 89 0.065
neural precursor cell proliferation GO:0061351 121 0.064
cytoplasmic transport GO:0016482 234 0.064
regulation of transmembrane transport GO:0034762 128 0.063
alpha beta t cell differentiation GO:0046632 69 0.063
positive regulation of lamellipodium organization GO:1902745 3 0.063
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.062
negative regulation of cellular protein metabolic process GO:0032269 247 0.062
cell substrate adhesion GO:0031589 130 0.062
regulation of establishment of protein localization GO:0070201 181 0.061
regulation of hormone levels GO:0010817 211 0.061
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
meiotic nuclear division GO:0007126 115 0.061
divalent inorganic cation transport GO:0072511 178 0.060
negative regulation of translation GO:0017148 22 0.060
negative regulation of organelle organization GO:0010639 90 0.060
multi organism behavior GO:0051705 62 0.060
Worm
negative regulation of cell cycle GO:0045786 123 0.060
negative regulation of secretion GO:0051048 61 0.060
negative regulation of phosphorylation GO:0042326 166 0.060
myotube differentiation GO:0014902 105 0.060
negative regulation of intracellular signal transduction GO:1902532 167 0.060
regulation of ion transmembrane transport GO:0034765 119 0.059
megakaryocyte differentiation GO:0030219 26 0.059
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.058
epidermis development GO:0008544 187 0.058
positive regulation of neuron differentiation GO:0045666 141 0.057
macromolecular complex disassembly GO:0032984 43 0.057
morphogenesis of embryonic epithelium GO:0016331 159 0.057
negative regulation of actin filament polymerization GO:0030837 11 0.056
regulation of metal ion transport GO:0010959 106 0.056
microtubule based transport GO:0010970 50 0.056
negative regulation of phosphorus metabolic process GO:0010563 184 0.055
guanosine containing compound catabolic process GO:1901069 144 0.054
amide transport GO:0042886 138 0.054
purine nucleoside catabolic process GO:0006152 205 0.054
regulation of protein stability GO:0031647 52 0.054
protein ubiquitination GO:0016567 171 0.053
skin development GO:0043588 220 0.053
rap protein signal transduction GO:0032486 3 0.052
positive regulation of cell cycle GO:0045787 92 0.052
peptide hormone secretion GO:0030072 109 0.052
regulation of canonical wnt signaling pathway GO:0060828 82 0.052
regulation of cell migration GO:0030334 219 0.052
protein depolymerization GO:0051261 34 0.052
regulation of neuron death GO:1901214 134 0.051
regulation of synaptic plasticity GO:0048167 87 0.051
organonitrogen compound catabolic process GO:1901565 264 0.051
rho protein signal transduction GO:0007266 32 0.050
oxidation reduction process GO:0055114 342 0.050
positive regulation of secretion by cell GO:1903532 114 0.049
ribonucleoside triphosphate metabolic process GO:0009199 220 0.049
negative regulation of synaptic vesicle transport GO:1902804 3 0.048
negative regulation of neuron death GO:1901215 98 0.048
oligodendrocyte development GO:0014003 20 0.048
cellular ion homeostasis GO:0006873 165 0.048
locomotory behavior GO:0007626 195 0.048
maintenance of location GO:0051235 89 0.047
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.047
nitrogen compound transport GO:0071705 271 0.047
regulation of receptor activity GO:0010469 41 0.047
regulation of nucleotide catabolic process GO:0030811 122 0.046
wnt signaling pathway GO:0016055 188 0.046
response to lipopolysaccharide GO:0032496 128 0.046
regulation of exocytosis GO:0017157 61 0.046
protein targeting GO:0006605 143 0.046
negative regulation of cellular amine metabolic process GO:0033239 1 0.045
positive regulation of gtp catabolic process GO:0033126 85 0.045
oocyte axis specification GO:0007309 2 0.045
cytoskeleton dependent intracellular transport GO:0030705 50 0.045
regulation of rho protein signal transduction GO:0035023 71 0.044
g protein coupled receptor signaling pathway GO:0007186 243 0.044
homeostasis of number of cells GO:0048872 210 0.044
intracellular protein transport GO:0006886 204 0.043
regulation of cell cycle process GO:0010564 160 0.043
mitotic cell cycle GO:0000278 195 0.043
regulation of transporter activity GO:0032409 57 0.043
regulation of intracellular transport GO:0032386 159 0.043
regulation of mapk cascade GO:0043408 248 0.042
t cell differentiation in thymus GO:0033077 77 0.042
anion transport GO:0006820 177 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
cellular lipid metabolic process GO:0044255 323 0.042
oocyte construction GO:0007308 2 0.042
regulation of ras gtpase activity GO:0032318 88 0.042
positive regulation of secretion GO:0051047 130 0.041
glycerolipid metabolic process GO:0046486 122 0.041
cell activation involved in immune response GO:0002263 126 0.041
regulation of endocytosis GO:0030100 69 0.040
Worm
synaptic vesicle recycling GO:0036465 19 0.040
cellular amine metabolic process GO:0044106 44 0.040
regulation of engulfment of apoptotic cell GO:1901074 2 0.039
Worm
alpha beta t cell activation GO:0046631 91 0.039
negative regulation of nervous system development GO:0051961 156 0.039
regulation of neuron apoptotic process GO:0043523 122 0.038
nucleoside catabolic process GO:0009164 206 0.038
exocytosis GO:0006887 121 0.038
blood vessel morphogenesis GO:0048514 285 0.037
oocyte anterior posterior axis specification GO:0007314 2 0.037
fatty acid metabolic process GO:0006631 121 0.037
nucleotide metabolic process GO:0009117 332 0.037
eye photoreceptor cell differentiation GO:0001754 41 0.037
segmentation GO:0035282 93 0.036
sensory perception GO:0007600 245 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.036
regulation of alpha beta t cell activation GO:0046634 53 0.036
synaptic vesicle transport GO:0048489 57 0.036
cellular divalent inorganic cation homeostasis GO:0072503 127 0.036
regulation of nucleoside metabolic process GO:0009118 130 0.036
cellular carbohydrate metabolic process GO:0044262 119 0.036
protein processing GO:0016485 163 0.036
microtubule cytoskeleton organization GO:0000226 157 0.035
negative regulation of protein depolymerization GO:1901880 21 0.035
substrate dependent cell migration GO:0006929 18 0.035
regulation of proteolysis GO:0030162 164 0.035
negative regulation of molecular function GO:0044092 258 0.035
epithelial tube formation GO:0072175 130 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.034
regulation of protein kinase activity GO:0045859 232 0.034
mapk cascade GO:0000165 281 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.033
immune effector process GO:0002252 321 0.033
positive regulation of homeostatic process GO:0032846 64 0.033
cellular chemical homeostasis GO:0055082 215 0.033
purine nucleotide catabolic process GO:0006195 211 0.033
neuron apoptotic process GO:0051402 142 0.033
erk1 and erk2 cascade GO:0070371 77 0.033
calcium ion dependent exocytosis GO:0017156 35 0.033
regulation of calcium ion transport GO:0051924 69 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
monocarboxylic acid metabolic process GO:0032787 191 0.032
positive regulation of protein modification process GO:0031401 299 0.032
positive regulation of nucleotide metabolic process GO:0045981 114 0.032
lamellipodium morphogenesis GO:0072673 5 0.032
microtubule based process GO:0007017 236 0.032
cell cycle switching GO:0060184 1 0.032
photoreceptor cell differentiation GO:0046530 52 0.032
negative regulation of neuron apoptotic process GO:0043524 92 0.032
metencephalon development GO:0022037 89 0.031
positive regulation of cytokine production GO:0001819 174 0.031
neuron death GO:0070997 154 0.031
positive regulation of neuron projection development GO:0010976 79 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.031
negative regulation of ras protein signal transduction GO:0046580 18 0.031
peptide transport GO:0015833 133 0.030
membrane invagination GO:0010324 17 0.030
Worm
developmental pigmentation GO:0048066 40 0.030
megakaryocyte development GO:0035855 15 0.030
activation of rac gtpase activity GO:0032863 2 0.030
cell maturation GO:0048469 127 0.030
cation transmembrane transport GO:0098655 266 0.030
regulation of actin filament bundle assembly GO:0032231 18 0.030
organic anion transport GO:0015711 137 0.029
regulation of neurotransmitter transport GO:0051588 35 0.029
protein kinase b signaling GO:0043491 74 0.029
regulation of postsynaptic membrane potential GO:0060078 48 0.029
cd4 positive alpha beta t cell activation GO:0035710 45 0.029
negative regulation of mapk cascade GO:0043409 65 0.029
pigmentation GO:0043473 71 0.029
regulation of cell division GO:0051302 76 0.029
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.029
positive regulation of mapk cascade GO:0043410 170 0.028
negative regulation of stress fiber assembly GO:0051497 4 0.028
defense response to bacterium GO:0042742 119 0.028
cytokine production GO:0001816 319 0.028
cellular ketone metabolic process GO:0042180 84 0.028
establishment of tissue polarity GO:0007164 28 0.028
mitochondrion organization GO:0007005 134 0.028
positive regulation of programmed cell death GO:0043068 218 0.028
response to organic cyclic compound GO:0014070 198 0.028
regulation of lymphocyte proliferation GO:0050670 117 0.028
cellular response to growth factor stimulus GO:0071363 197 0.028
pole plasm assembly GO:0007315 2 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.028
lipid localization GO:0010876 126 0.028
negative regulation of cell proliferation GO:0008285 296 0.027
protein catabolic process GO:0030163 221 0.027
positive regulation of rac gtpase activity GO:0032855 14 0.027
regulation of peptidase activity GO:0052547 96 0.027
activation of immune response GO:0002253 138 0.027
regulation of rho gtpase activity GO:0032319 58 0.027
defecation GO:0030421 1 0.027
positive regulation of gtpase activity GO:0043547 85 0.027
negative regulation of growth GO:0045926 99 0.027
calcium ion transmembrane transport GO:0070588 85 0.027
leukocyte activation involved in immune response GO:0002366 126 0.027
positive regulation of phagocytosis engulfment GO:0060100 3 0.027
Worm
inositol phosphate catabolic process GO:0071545 4 0.027
generation of precursor metabolites and energy GO:0006091 103 0.027
cytokinesis GO:0000910 17 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.026
sequestering of metal ion GO:0051238 19 0.026
receptor mediated endocytosis GO:0006898 51 0.026
Worm
cellular macromolecule catabolic process GO:0044265 206 0.026
cellular response to organic cyclic compound GO:0071407 87 0.026
somite development GO:0061053 81 0.026
cellular response to molecule of bacterial origin GO:0071219 83 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
regulation of endopeptidase activity GO:0052548 89 0.026
inorganic ion transmembrane transport GO:0098660 234 0.026
oogenesis GO:0048477 56 0.026
protein autophosphorylation GO:0046777 61 0.026
response to radiation GO:0009314 165 0.025
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.025
canonical wnt signaling pathway GO:0060070 130 0.025
cellular response to biotic stimulus GO:0071216 92 0.025
hormone secretion GO:0046879 128 0.025
leukocyte apoptotic process GO:0071887 71 0.025
learning or memory GO:0007611 148 0.025
Mouse
phosphatidylinositol metabolic process GO:0046488 45 0.025
positive regulation of cell activation GO:0050867 158 0.025
positive regulation of ion transport GO:0043270 65 0.025
positive regulation of proteolysis GO:0045862 85 0.025
protein secretion GO:0009306 111 0.025
positive regulation of t cell activation GO:0050870 101 0.025
defense response to other organism GO:0098542 197 0.025
barbed end actin filament capping GO:0051016 6 0.025
positive regulation of leukocyte differentiation GO:1902107 86 0.025
metal ion homeostasis GO:0055065 189 0.025
regulation of protein complex disassembly GO:0043244 28 0.025
ribonucleoside catabolic process GO:0042454 206 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
positive regulation of endopeptidase activity GO:0010950 43 0.024
positive regulation of kinase activity GO:0033674 155 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
regulation of meiotic cell cycle GO:0051445 34 0.024
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.024
regulation of gtp catabolic process GO:0033124 113 0.024
positive regulation of rac protein signal transduction GO:0035022 1 0.024
phosphorylated carbohydrate dephosphorylation GO:0046838 4 0.024
cellular calcium ion homeostasis GO:0006874 119 0.024
maternal determination of anterior posterior axis embryo GO:0008358 2 0.024
positive regulation of endocytosis GO:0045807 42 0.023
Worm
mitotic cell cycle process GO:1903047 159 0.023
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.023
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
i kappab kinase nf kappab signaling GO:0007249 85 0.023
hindbrain development GO:0030902 128 0.022
carbohydrate metabolic process GO:0005975 230 0.022
cellular homeostasis GO:0019725 240 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
carbohydrate biosynthetic process GO:0016051 74 0.022
regulation of cytoplasmic transport GO:1903649 112 0.022
regulation of feeding behavior GO:0060259 3 0.022
positive regulation of apoptotic signaling pathway GO:2001235 95 0.022
regulation of carbohydrate metabolic process GO:0006109 75 0.022
ameboidal type cell migration GO:0001667 128 0.022
calcium ion homeostasis GO:0055074 127 0.022
positive regulation of myelination GO:0031643 5 0.022
negative regulation of mitotic cell cycle GO:0045930 58 0.022
positive regulation of dendrite development GO:1900006 21 0.021
regulation of stress fiber assembly GO:0051492 15 0.021
plasma membrane organization GO:0007009 90 0.021
response to fibroblast growth factor GO:0071774 47 0.021
positive regulation of transferase activity GO:0051347 167 0.021
pigment metabolic process GO:0042440 32 0.021
negative regulation of cell migration GO:0030336 59 0.021
regulation of protein tyrosine kinase activity GO:0061097 17 0.021
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.021
protein maturation GO:0051604 176 0.021
regulation of neurological system process GO:0031644 22 0.020
regulation of myelination GO:0031641 20 0.020
regulation of rac protein signal transduction GO:0035020 19 0.020
protein localization to plasma membrane GO:0072659 57 0.020
regulation of actin nucleation GO:0051125 4 0.020
positive regulation of insulin secretion GO:0032024 26 0.020
cellular response to lipopolysaccharide GO:0071222 77 0.020
learning GO:0007612 98 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
response to oxidative stress GO:0006979 123 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
peptidyl serine phosphorylation GO:0018105 74 0.020
peptide secretion GO:0002790 114 0.020
regulation of erk1 and erk2 cascade GO:0070372 71 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.020
b cell differentiation GO:0030183 78 0.020
regulation of ras protein signal transduction GO:0046578 114 0.019
substrate adhesion dependent cell spreading GO:0034446 30 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
connective tissue development GO:0061448 179 0.019
negative regulation of protein complex assembly GO:0031333 25 0.019
regulation of organ morphogenesis GO:2000027 144 0.019
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.019
genitalia development GO:0048806 37 0.019
Worm
small molecule catabolic process GO:0044282 71 0.019
peptidyl amino acid modification GO:0018193 336 0.019

Abi1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
non syndromic intellectual disability DOID:0050889 0 0.054
disease of mental health DOID:150 0 0.054
developmental disorder of mental health DOID:0060037 0 0.054
specific developmental disorder DOID:0060038 0 0.054
intellectual disability DOID:1059 0 0.054
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
sensory system disease DOID:0050155 0 0.021