Mus musculus

0 known processes

Tmem50a

transmembrane protein 50A

(Aliases: Smp1,3200001F09Rik,CAM)

Tmem50a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
macromolecule catabolic process GO:0009057 281 0.091
negative regulation of protein metabolic process GO:0051248 282 0.068
protein catabolic process GO:0030163 221 0.053
apoptotic signaling pathway GO:0097190 306 0.041
protein maturation GO:0051604 176 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cellular ketone metabolic process GO:0042180 84 0.039
negative regulation of molecular function GO:0044092 258 0.039
cellular amine metabolic process GO:0044106 44 0.037
cellular macromolecule catabolic process GO:0044265 206 0.035
cellular lipid metabolic process GO:0044255 323 0.035
regulation of peptidase activity GO:0052547 96 0.034
protein processing GO:0016485 163 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
immune effector process GO:0002252 321 0.031
cellular amino acid metabolic process GO:0006520 103 0.030
organic cyclic compound catabolic process GO:1901361 295 0.029
regulation of mapk cascade GO:0043408 248 0.029
carbohydrate homeostasis GO:0033500 128 0.028
regulation of hormone levels GO:0010817 211 0.027
amine metabolic process GO:0009308 45 0.027
negative regulation of cell proliferation GO:0008285 296 0.026
positive regulation of cell death GO:0010942 224 0.026
endocytosis GO:0006897 168 0.026
regulation of hydrolase activity GO:0051336 246 0.026
cytoplasmic transport GO:0016482 234 0.026
response to radiation GO:0009314 165 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
negative regulation of protein processing GO:0010955 79 0.025
inflammatory response GO:0006954 244 0.025
regulation of secretion GO:0051046 274 0.024
cellular homeostasis GO:0019725 240 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
cation transport GO:0006812 399 0.023
mapk cascade GO:0000165 281 0.023
response to oxidative stress GO:0006979 123 0.023
negative regulation of protein maturation GO:1903318 79 0.023
glucose homeostasis GO:0042593 128 0.022
regulation of membrane potential GO:0042391 192 0.022
oxidation reduction process GO:0055114 342 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
cellular protein catabolic process GO:0044257 155 0.022
regulation of transferase activity GO:0051338 263 0.022
nitrogen compound transport GO:0071705 271 0.021
membrane organization GO:0061024 245 0.021
cytokine production GO:0001816 319 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
divalent inorganic cation transport GO:0072511 178 0.021
nucleotide metabolic process GO:0009117 332 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
cation homeostasis GO:0055080 212 0.021
lymphocyte mediated immunity GO:0002449 139 0.020
regulation of secretion by cell GO:1903530 249 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
innate immune response GO:0045087 157 0.020
actin cytoskeleton organization GO:0030036 220 0.020
male gamete generation GO:0048232 285 0.020
transmembrane transport GO:0055085 412 0.020
cellular chemical homeostasis GO:0055082 215 0.020
regulation of protein processing GO:0070613 96 0.020
positive regulation of mapk cascade GO:0043410 170 0.019
lipid biosynthetic process GO:0008610 179 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of protein maturation GO:1903317 96 0.019
metal ion homeostasis GO:0055065 189 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
spermatogenesis GO:0007283 284 0.018
circulatory system process GO:0003013 197 0.018
positive regulation of apoptotic signaling pathway GO:2001235 95 0.018
vesicle organization GO:0016050 60 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
cation transmembrane transport GO:0098655 266 0.018
maintenance of location GO:0051235 89 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
response to organic cyclic compound GO:0014070 198 0.018
aromatic compound catabolic process GO:0019439 286 0.017
peptidyl amino acid modification GO:0018193 336 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
regulation of protein catabolic process GO:0042176 108 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
dna metabolic process GO:0006259 303 0.017
purine containing compound metabolic process GO:0072521 311 0.017
protein localization to organelle GO:0033365 185 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
heterocycle catabolic process GO:0046700 280 0.017
positive regulation of cell development GO:0010720 237 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of cell cycle GO:0051726 281 0.016
mitochondrion organization GO:0007005 134 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
leukocyte mediated immunity GO:0002443 174 0.016
protein ubiquitination GO:0016567 171 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
regulation of cell activation GO:0050865 289 0.016
ras protein signal transduction GO:0007265 77 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
intracellular protein transport GO:0006886 204 0.016
response to extracellular stimulus GO:0009991 127 0.016
ossification GO:0001503 216 0.016
response to nutrient levels GO:0031667 109 0.015
positive regulation of protein modification process GO:0031401 299 0.015
regulation of proteolysis GO:0030162 164 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
leukocyte differentiation GO:0002521 342 0.015
calcium ion transport GO:0006816 159 0.015
skeletal system development GO:0001501 356 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
regulation of kinase activity GO:0043549 249 0.015
negative regulation of protein modification process GO:0031400 163 0.015
endomembrane system organization GO:0010256 147 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
muscle tissue development GO:0060537 308 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.014
cellular response to oxidative stress GO:0034599 76 0.014
regulation of body fluid levels GO:0050878 162 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
response to light stimulus GO:0009416 135 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
regulation of system process GO:0044057 200 0.014
regulation of organelle organization GO:0033043 289 0.014
cellular ion homeostasis GO:0006873 165 0.014
gland development GO:0048732 330 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
response to organonitrogen compound GO:0010243 246 0.014
regulation of endopeptidase activity GO:0052548 89 0.013
negative regulation of proteolysis GO:0045861 74 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
blood circulation GO:0008015 195 0.013
t cell activation GO:0042110 289 0.013
regulation of intracellular transport GO:0032386 159 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
cell killing GO:0001906 67 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
negative regulation of glycoprotein metabolic process GO:1903019 3 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
germ cell development GO:0007281 185 0.013
microtubule based process GO:0007017 236 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
organic hydroxy compound transport GO:0015850 93 0.013
regulation of cytokine production GO:0001817 266 0.013
glycoprotein metabolic process GO:0009100 116 0.013
regulation of defense response GO:0031347 233 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
carbohydrate metabolic process GO:0005975 230 0.013
sensory perception GO:0007600 245 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
regulation of ion transport GO:0043269 215 0.013
regulation of homeostatic process GO:0032844 182 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
phospholipid metabolic process GO:0006644 87 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.012
leukocyte mediated cytotoxicity GO:0001909 62 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of cellular response to stress GO:0080135 159 0.012
tissue remodeling GO:0048771 102 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
wound healing GO:0042060 157 0.012
cellular response to lipid GO:0071396 145 0.012
regulation of cell projection organization GO:0031344 206 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
calcium ion homeostasis GO:0055074 127 0.012
positive regulation of secretion GO:0051047 130 0.012
hormone secretion GO:0046879 128 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
fat cell differentiation GO:0045444 160 0.012
nuclear transport GO:0051169 139 0.012
camera type eye development GO:0043010 266 0.012
regulation of neuron differentiation GO:0045664 281 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
organophosphate catabolic process GO:0046434 232 0.012
locomotory behavior GO:0007626 195 0.012
cellular protein complex assembly GO:0043623 116 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
wnt signaling pathway GO:0016055 188 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
myeloid cell differentiation GO:0030099 233 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
synaptic transmission GO:0007268 329 0.011
regulation of cell motility GO:2000145 236 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of t cell activation GO:0050863 170 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
cell adhesion GO:0007155 329 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
positive regulation of nervous system development GO:0051962 221 0.011
gonad development GO:0008406 141 0.011
striated muscle tissue development GO:0014706 293 0.011
divalent metal ion transport GO:0070838 172 0.011
multicellular organismal signaling GO:0035637 91 0.011
positive regulation of macroautophagy GO:0016239 3 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
development of primary sexual characteristics GO:0045137 143 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
negative regulation of cell cycle GO:0045786 123 0.011
organelle localization GO:0051640 179 0.011
regulation of inflammatory response GO:0050727 147 0.011
ion transmembrane transport GO:0034220 361 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
fertilization GO:0009566 127 0.011
response to oxygen levels GO:0070482 62 0.011
sensory system development GO:0048880 3 0.011
skeletal muscle organ development GO:0060538 163 0.011
response to starvation GO:0042594 65 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
lipid localization GO:0010876 126 0.011
nucleoside metabolic process GO:0009116 246 0.011
negative regulation of peptidase activity GO:0010466 46 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
negative regulation of osteoblast proliferation GO:0033689 4 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
positive regulation of homeostatic process GO:0032846 64 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
organelle fission GO:0048285 170 0.010
cofactor metabolic process GO:0051186 80 0.010
digestive tract development GO:0048565 190 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
regulation of binding GO:0051098 111 0.010
membrane fusion GO:0061025 38 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
cell type specific apoptotic process GO:0097285 268 0.010
sterol homeostasis GO:0055092 45 0.010
negative regulation of hydrolase activity GO:0051346 71 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
lymphocyte proliferation GO:0046651 164 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
developmental maturation GO:0021700 193 0.010
sphingolipid metabolic process GO:0006665 45 0.010
muscle system process GO:0003012 141 0.010

Tmem50a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.078
inherited metabolic disorder DOID:655 0 0.045
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
central nervous system disease DOID:331 0 0.022
immune system disease DOID:2914 0 0.016
sensory system disease DOID:0050155 0 0.016
lipid storage disease DOID:9455 0 0.015
lysosomal storage disease DOID:3211 0 0.015
acquired metabolic disease DOID:0060158 0 0.015
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
retinal disease DOID:5679 0 0.011