Mus musculus

39 known processes

Lrrtm4

leucine rich repeat transmembrane neuronal 4

(Aliases: 7530419J18Rik,A230052N11)

Lrrtm4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.188
ion transmembrane transport GO:0034220 361 0.132
cation transport GO:0006812 399 0.102
axonogenesis GO:0007409 274 0.063
positive regulation of nervous system development GO:0051962 221 0.059
synaptic transmission GO:0007268 329 0.054
Mouse
cell adhesion GO:0007155 329 0.054
inorganic ion transmembrane transport GO:0098660 234 0.053
regulation of neuron differentiation GO:0045664 281 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
locomotory behavior GO:0007626 195 0.046
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.045
skeletal system development GO:0001501 356 0.044
Mouse
action potential GO:0001508 78 0.043
regulation of organelle organization GO:0033043 289 0.042
regulation of ion transport GO:0043269 215 0.041
sensory perception GO:0007600 245 0.040
regulation of secretion GO:0051046 274 0.038
membrane organization GO:0061024 245 0.038
positive regulation of cell development GO:0010720 237 0.038
cellular ketone metabolic process GO:0042180 84 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
amine metabolic process GO:0009308 45 0.035
regulation of system process GO:0044057 200 0.035
response to organonitrogen compound GO:0010243 246 0.035
forebrain development GO:0030900 302 0.034
learning or memory GO:0007611 148 0.034
nitrogen compound transport GO:0071705 271 0.034
multicellular organismal signaling GO:0035637 91 0.033
cation homeostasis GO:0055080 212 0.033
regulation of membrane potential GO:0042391 192 0.033
regulation of secretion by cell GO:1903530 249 0.033
metal ion homeostasis GO:0055065 189 0.033
cellular amine metabolic process GO:0044106 44 0.033
ribonucleotide metabolic process GO:0009259 291 0.032
ossification GO:0001503 216 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
calcium ion transport GO:0006816 159 0.032
cytoplasmic transport GO:0016482 234 0.031
divalent inorganic cation transport GO:0072511 178 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
positive regulation of neuron differentiation GO:0045666 141 0.030
cellular protein complex assembly GO:0043623 116 0.030
cellular chemical homeostasis GO:0055082 215 0.030
cellular homeostasis GO:0019725 240 0.030
positive regulation of protein modification process GO:0031401 299 0.029
neuronal action potential GO:0019228 54 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.029
cognition GO:0050890 149 0.029
oxidation reduction process GO:0055114 342 0.028
divalent metal ion transport GO:0070838 172 0.028
muscle tissue development GO:0060537 308 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
apoptotic signaling pathway GO:0097190 306 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
microtubule based process GO:0007017 236 0.027
macromolecule catabolic process GO:0009057 281 0.027
protein catabolic process GO:0030163 221 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
regulation of cell projection organization GO:0031344 206 0.027
maintenance of location GO:0051235 89 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
neuron migration GO:0001764 122 0.026
transmission of nerve impulse GO:0019226 76 0.026
actin cytoskeleton organization GO:0030036 220 0.026
endocytosis GO:0006897 168 0.025
Mouse
skeletal system morphogenesis GO:0048705 203 0.025
Mouse
carbohydrate homeostasis GO:0033500 128 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
negative regulation of nervous system development GO:0051961 156 0.024
developmental growth involved in morphogenesis GO:0060560 138 0.024
organic hydroxy compound transport GO:0015850 93 0.024
peptidyl amino acid modification GO:0018193 336 0.024
regulation of neuron projection development GO:0010975 169 0.023
organelle localization GO:0051640 179 0.023
anion transport GO:0006820 177 0.023
regulation of hydrolase activity GO:0051336 246 0.023
response to organic cyclic compound GO:0014070 198 0.022
regulation of anatomical structure size GO:0090066 178 0.022
synapse organization GO:0050808 125 0.022
adult behavior GO:0030534 135 0.022
calcium ion homeostasis GO:0055074 127 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
Mouse
nucleotide metabolic process GO:0009117 332 0.022
glucose homeostasis GO:0042593 128 0.021
regulation of transferase activity GO:0051338 263 0.021
gliogenesis GO:0042063 141 0.021
anion transmembrane transport GO:0098656 71 0.021
regulation of synaptic plasticity GO:0048167 87 0.021
Mouse
negative regulation of molecular function GO:0044092 258 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
negative regulation of cell development GO:0010721 169 0.020
cellular ion homeostasis GO:0006873 165 0.020
cytokine production GO:0001816 319 0.020
circulatory system process GO:0003013 197 0.020
leukocyte differentiation GO:0002521 342 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
cell type specific apoptotic process GO:0097285 268 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
regulation of homeostatic process GO:0032844 182 0.020
regulation of cellular component size GO:0032535 121 0.020
stem cell differentiation GO:0048863 268 0.020
telencephalon development GO:0021537 186 0.020
small gtpase mediated signal transduction GO:0007264 97 0.019
mapk cascade GO:0000165 281 0.019
muscle cell differentiation GO:0042692 261 0.019
cardiac muscle cell contraction GO:0086003 7 0.019
carboxylic acid transport GO:0046942 100 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
compound eye development GO:0048749 1 0.019
protein localization to membrane GO:0072657 108 0.019
protein localization to organelle GO:0033365 185 0.019
positive regulation of transferase activity GO:0051347 167 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
bone development GO:0060348 120 0.019
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
regulation of metal ion transport GO:0010959 106 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.018
regulation of hormone levels GO:0010817 211 0.018
regulation of cell cycle GO:0051726 281 0.018
homeostasis of number of cells GO:0048872 210 0.018
gland development GO:0048732 330 0.018
regulation of transmembrane transport GO:0034762 128 0.018
neuron projection guidance GO:0097485 141 0.018
protein ubiquitination GO:0016567 171 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
cation transmembrane transport GO:0098655 266 0.018
intracellular protein transport GO:0006886 204 0.018
regulation of cell adhesion GO:0030155 154 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
positive regulation of neuron projection development GO:0010976 79 0.018
regulation of feeding behavior GO:0060259 3 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
neuromuscular process GO:0050905 99 0.018
lipid localization GO:0010876 126 0.018
striated muscle tissue development GO:0014706 293 0.018
regulation of organ morphogenesis GO:2000027 144 0.017
Mouse
regulation of postsynaptic membrane potential GO:0060078 48 0.017
presynaptic membrane organization GO:0097090 8 0.017
fat cell differentiation GO:0045444 160 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
sensory perception of mechanical stimulus GO:0050954 107 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
dendrite development GO:0016358 115 0.017
regulation of protein kinase activity GO:0045859 232 0.017
immune effector process GO:0002252 321 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
regulation of mapk cascade GO:0043408 248 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
learning GO:0007612 98 0.017
blood circulation GO:0008015 195 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of actin filament based process GO:0032970 99 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
glial cell differentiation GO:0010001 131 0.017
renal system development GO:0072001 225 0.017
cellular macromolecule catabolic process GO:0044265 206 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
nucleoside metabolic process GO:0009116 246 0.016
hormone secretion GO:0046879 128 0.016
regionalization GO:0003002 337 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
lipid transport GO:0006869 98 0.016
carbohydrate metabolic process GO:0005975 230 0.016
smoothened signaling pathway GO:0007224 105 0.016
purine containing compound metabolic process GO:0072521 311 0.016
multicellular organismal response to stress GO:0033555 62 0.016
protein polymerization GO:0051258 57 0.016
ras protein signal transduction GO:0007265 77 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
anatomical structure homeostasis GO:0060249 145 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
multi multicellular organism process GO:0044706 109 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
cellular response to ammonium ion GO:0071242 2 0.016
single organism cell adhesion GO:0098602 156 0.016
heart morphogenesis GO:0003007 178 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
cell maturation GO:0048469 127 0.015
cyclic nucleotide metabolic process GO:0009187 59 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
regulation of ossification GO:0030278 112 0.015
diencephalon development GO:0021536 63 0.015
sequestering of calcium ion GO:0051208 18 0.015
oocyte axis specification GO:0007309 2 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
ear development GO:0043583 200 0.015
germ cell development GO:0007281 185 0.015
actin filament organization GO:0007015 113 0.015
cellular response to lipid GO:0071396 145 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
organic acid transport GO:0015849 101 0.015
regulation of multi organism process GO:0043900 111 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
positive regulation of organelle organization GO:0010638 128 0.015
multi organism behavior GO:0051705 62 0.015
exocytosis GO:0006887 121 0.015
developmental cell growth GO:0048588 84 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
lipid biosynthetic process GO:0008610 179 0.015
cellular protein catabolic process GO:0044257 155 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
angiogenesis GO:0001525 201 0.014
wnt signaling pathway GO:0016055 188 0.014
camera type eye development GO:0043010 266 0.014
cell substrate adhesion GO:0031589 130 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
urogenital system development GO:0001655 261 0.014
nucleotide biosynthetic process GO:0009165 78 0.014
regulation of cell activation GO:0050865 289 0.014
regulation of cytokine production GO:0001817 266 0.014
respiratory system development GO:0060541 190 0.014
inflammatory response GO:0006954 244 0.014
adult locomotory behavior GO:0008344 91 0.014
positive regulation of secretion GO:0051047 130 0.014
sensory perception of sound GO:0007605 97 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
digestive system development GO:0055123 200 0.014
regulation of cell cycle process GO:0010564 160 0.014
oocyte construction GO:0007308 2 0.014
regulation of kinase activity GO:0043549 249 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
response to oxygen levels GO:0070482 62 0.014
myelination GO:0042552 74 0.013
cellular lipid metabolic process GO:0044255 323 0.013
chemotaxis GO:0006935 247 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
response to radiation GO:0009314 165 0.013
protein maturation GO:0051604 176 0.013
stem cell maintenance GO:0019827 130 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
mitotic cell cycle GO:0000278 195 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
developmental maturation GO:0021700 193 0.013
ensheathment of neurons GO:0007272 76 0.013
rhythmic process GO:0048511 174 0.013
male genitalia morphogenesis GO:0048808 4 0.013
establishment of organelle localization GO:0051656 122 0.013
regulation of proteolysis GO:0030162 164 0.013
positive regulation of ion transport GO:0043270 65 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
aromatic compound catabolic process GO:0019439 286 0.013
glycoprotein metabolic process GO:0009100 116 0.013
skeletal muscle organ development GO:0060538 163 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
placenta development GO:0001890 140 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
negative regulation of organelle organization GO:0010639 90 0.013
regulation of blood circulation GO:1903522 93 0.013
male gamete generation GO:0048232 285 0.013
multicellular organism growth GO:0035264 161 0.013
retina development in camera type eye GO:0060041 119 0.013
actin filament based movement GO:0030048 23 0.013
vesicle localization GO:0051648 86 0.013
protein targeting GO:0006605 143 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
extracellular structure organization GO:0043062 148 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
t cell activation GO:0042110 289 0.012
peptide hormone secretion GO:0030072 109 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
negative regulation of cell cycle GO:0045786 123 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
skin development GO:0043588 220 0.012
regulation of body fluid levels GO:0050878 162 0.012
neural precursor cell proliferation GO:0061351 121 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
regulation of cell motility GO:2000145 236 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
membrane depolarization GO:0051899 64 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
heterocycle catabolic process GO:0046700 280 0.012
regulation of map kinase activity GO:0043405 120 0.012
detection of abiotic stimulus GO:0009582 60 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
regulation of protein catabolic process GO:0042176 108 0.012
extracellular matrix organization GO:0030198 147 0.012
regulation of protein maturation GO:1903317 96 0.012
organelle assembly GO:0070925 177 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
nuclear transport GO:0051169 139 0.012
protein import GO:0017038 101 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
myeloid cell differentiation GO:0030099 233 0.012
rna processing GO:0006396 105 0.012
respiratory tube development GO:0030323 167 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
synapse assembly GO:0007416 56 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
sensory organ morphogenesis GO:0090596 242 0.012
dephosphorylation GO:0016311 129 0.012
adult walking behavior GO:0007628 41 0.011
axon ensheathment GO:0008366 76 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
cell growth GO:0016049 130 0.011
axon guidance GO:0007411 141 0.011
tissue homeostasis GO:0001894 115 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
cell recognition GO:0008037 83 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
visual perception GO:0007601 52 0.011
response to light stimulus GO:0009416 135 0.011
wound healing GO:0042060 157 0.011
regulation of peptide transport GO:0090087 91 0.011
inner ear receptor cell differentiation GO:0060113 61 0.011
peptide transport GO:0015833 133 0.011
feeding behavior GO:0007631 62 0.011
blood vessel morphogenesis GO:0048514 285 0.011
muscle contraction GO:0006936 101 0.011
development of primary sexual characteristics GO:0045137 143 0.011
tissue remodeling GO:0048771 102 0.011
methylation GO:0032259 134 0.011
spermatid differentiation GO:0048515 115 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
cell fate commitment GO:0045165 210 0.011
lymphocyte differentiation GO:0030098 242 0.011
actin filament polymerization GO:0030041 44 0.011
detection of stimulus GO:0051606 84 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
protein import into nucleus GO:0006606 95 0.011
glutamate receptor signaling pathway GO:0007215 35 0.011
regulation of protein transport GO:0051223 163 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
mitotic cell cycle process GO:1903047 159 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
pole plasm assembly GO:0007315 2 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
regulation of response to drug GO:2001023 2 0.011
positive regulation of cell death GO:0010942 224 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
response to growth factor GO:0070848 198 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of protein complex assembly GO:0043254 83 0.011
regulation of blood pressure GO:0008217 93 0.011
nerve development GO:0021675 67 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
regulation of response to wounding GO:1903034 189 0.010
intracellular mrna localization GO:0008298 4 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
negative regulation of multi organism process GO:0043901 68 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
defecation GO:0030421 1 0.010
calcium ion transmembrane transport GO:0070588 85 0.010
regulation of cell substrate adhesion GO:0010810 73 0.010
rho protein signal transduction GO:0007266 32 0.010
organic anion transport GO:0015711 137 0.010
protein processing GO:0016485 163 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
ameboidal type cell migration GO:0001667 128 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
bmp signaling pathway GO:0030509 93 0.010
memory GO:0007613 58 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
camp metabolic process GO:0046058 40 0.010
mitochondrion organization GO:0007005 134 0.010
cell junction organization GO:0034330 77 0.010
male anatomical structure morphogenesis GO:0090598 4 0.010
cartilage development GO:0051216 140 0.010
chromatin organization GO:0006325 206 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
pallium development GO:0021543 120 0.010
female sex differentiation GO:0046660 84 0.010
chromatin modification GO:0016568 187 0.010
positive regulation of protein transport GO:0051222 93 0.010
oocyte anterior posterior axis specification GO:0007314 2 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
regulation of protein localization GO:0032880 231 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
mrna metabolic process GO:0016071 84 0.010
amino acid transport GO:0006865 61 0.010
negative regulation of neuron differentiation GO:0045665 101 0.010

Lrrtm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.013
central nervous system disease DOID:331 0 0.012