|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.568
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.429
|
Yeast Mouse Worm Fly |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.354
|
Mouse Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.343
|
Yeast Mouse Worm Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.334
|
Yeast Mouse Worm Fly |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.333
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.312
|
Yeast Mouse Worm Fly |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.307
|
Yeast Mouse Worm Fly |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.270
|
Yeast Mouse Worm Fly |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.266
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.255
|
Yeast Mouse Worm Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.238
|
Yeast Mouse Worm Fly |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.234
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.230
|
Yeast Mouse Worm Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.227
|
Yeast Mouse Worm Fly |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.219
|
Yeast Mouse Worm Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.218
|
Yeast Mouse Worm Fly |
|
|
wound healing
|
GO:0042060 |
157 |
0.210
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.209
|
Yeast Mouse Worm Fly |
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.204
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.204
|
Yeast Mouse Worm Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.203
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.197
|
Yeast Mouse Worm Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.193
|
Yeast Mouse Worm Fly |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.192
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.191
|
Yeast Mouse Worm Fly |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.185
|
Yeast Mouse Worm Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.184
|
Yeast Mouse Worm Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.181
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.173
|
Yeast Mouse Worm Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.164
|
Yeast Mouse Worm Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.163
|
Yeast Mouse Worm Fly |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.162
|
Yeast Mouse Worm Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.161
|
Yeast Mouse Worm Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.157
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.156
|
Yeast Mouse Fly |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.155
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.154
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.153
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.152
|
Yeast Mouse Worm Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.151
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.149
|
Yeast Mouse Worm Fly |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.148
|
Yeast Mouse Worm Fly |
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.143
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.139
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.135
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.134
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.133
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.132
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.130
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.130
|
Yeast |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.129
|
Yeast Mouse Worm Fly |
|
|
ossification
|
GO:0001503 |
216 |
0.124
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.123
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.115
|
Worm |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.115
|
Yeast Mouse Worm Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.107
|
Yeast Mouse Worm Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.106
|
Yeast Mouse Worm Fly |
|
|
regulation of integrin mediated signaling pathway
|
GO:2001044 |
8 |
0.106
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.104
|
Yeast Fly |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.104
|
Yeast |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.103
|
Yeast Mouse Worm Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.103
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.101
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.099
|
Worm |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.097
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.096
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.096
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.096
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.095
|
Yeast Mouse Worm Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.090
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.088
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.087
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.085
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.084
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.084
|
Yeast Mouse Worm Fly |
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.080
|
Mouse Worm Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.079
|
Yeast |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.074
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.074
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.074
|
Fly |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.073
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.073
|
Yeast Mouse Worm Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.073
|
Yeast Mouse Worm Fly |
|
|
cell growth
|
GO:0016049 |
130 |
0.072
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.072
|
Yeast Mouse Worm Fly |
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.071
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.070
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.070
|
Mouse |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.069
|
Yeast Mouse Worm Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.069
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.069
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.068
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.068
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.068
|
Yeast |
|
|
protein maturation
|
GO:0051604 |
176 |
0.067
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.066
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.065
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.064
|
Fly |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.064
|
Yeast Mouse Worm Fly |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.064
|
Yeast Mouse Worm Fly |
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.063
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.062
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.062
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.061
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.060
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.058
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.058
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.057
|
Worm |
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.057
|
Worm |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.057
|
Yeast Mouse Worm Fly |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.057
|
Yeast |
|
|
hemostasis
|
GO:0007599 |
78 |
0.056
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.056
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.055
|
Yeast Mouse Worm Fly |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.055
|
|
|
|
positive regulation of integrin mediated signaling pathway
|
GO:2001046 |
5 |
0.055
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.055
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
2 |
0.055
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.054
|
|
|
|
fibrinolysis
|
GO:0042730 |
3 |
0.054
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.052
|
Worm |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.052
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.051
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.050
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.050
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.050
|
Fly |
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.050
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.049
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.049
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.049
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.048
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.048
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.048
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.048
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.048
|
Fly |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.048
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.048
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.047
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.047
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.047
|
Yeast Mouse Worm Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.047
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.046
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.046
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.045
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.044
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.044
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.044
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.043
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.043
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.043
|
Worm |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.043
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.042
|
|
|
|
membrane raft assembly
|
GO:0001765 |
3 |
0.042
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.041
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.041
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.041
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.040
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.040
|
Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.040
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.040
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.039
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.039
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.039
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.039
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
136 |
0.038
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.038
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.038
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.038
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.038
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.038
|
Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.037
|
Yeast |
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.037
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.037
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.036
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.036
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.036
|
Yeast |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.036
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.036
|
Mouse |
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.036
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.036
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.035
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.035
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.035
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.035
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.035
|
Mouse Fly |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.035
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.035
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.035
|
Yeast Mouse Worm Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.035
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.035
|
Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.034
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
34 |
0.034
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.034
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.034
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.034
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.033
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.033
|
|
|
|
chloride transport
|
GO:0006821 |
32 |
0.033
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.033
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.033
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.032
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.032
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.032
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.032
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.031
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.031
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.031
|
Fly |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.031
|
Fly |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.031
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.031
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.031
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.030
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.030
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.030
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
19 |
0.030
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.030
|
Fly |
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
4 |
0.029
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.029
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.029
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.028
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.028
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.028
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.028
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.028
|
Mouse |
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
24 |
0.028
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
24 |
0.028
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.028
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.028
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.028
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.028
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.027
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.027
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.027
|
Mouse |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.027
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.027
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.027
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.027
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.027
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.027
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.027
|
|
|
|
protein heterotetramerization
|
GO:0051290 |
4 |
0.027
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.027
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.027
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.027
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.027
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.026
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.026
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.026
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.026
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.026
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.026
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.026
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.026
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.026
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.025
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.025
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.025
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.025
|
Fly |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.025
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.025
|
Fly |
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.024
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.024
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.024
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.024
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.024
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.024
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.024
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.024
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.024
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.024
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.024
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.023
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.023
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.023
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.023
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
2 |
0.023
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.023
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.023
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.023
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.023
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.023
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.023
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.022
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.022
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.022
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.022
|
Fly |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.022
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.022
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.022
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.022
|
Mouse Fly |
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
19 |
0.022
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.021
|
Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.021
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.021
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.021
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.021
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.021
|
Worm |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.021
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.021
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.021
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.021
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
32 |
0.021
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.021
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.021
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.021
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.021
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.020
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.020
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.020
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.020
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.020
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.020
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.020
|
Mouse |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.020
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.020
|
Fly |
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.020
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.020
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.020
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.020
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.020
|
Fly |
|
|
sensory perception
|
GO:0007600 |
245 |
0.020
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.019
|
|
|
|
acetate ester transport
|
GO:1901374 |
2 |
0.019
|
Worm |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.019
|
Worm |
|
|
exocytosis
|
GO:0006887 |
121 |
0.019
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.019
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.019
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.019
|
Mouse |
|
|
lipid transport
|
GO:0006869 |
98 |
0.019
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.019
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.019
|
Yeast Fly |
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
4 |
0.019
|
|
|
|
epiboly
|
GO:0090504 |
8 |
0.019
|
|
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.019
|
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.019
|
Worm |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.019
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.019
|
Worm |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.019
|
|
|
|
cytokinetic process
|
GO:0032506 |
2 |
0.019
|
Worm Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.019
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.019
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.018
|
Worm Fly |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.018
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.018
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.018
|
Worm |
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.018
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.018
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.018
|
Fly |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.018
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.018
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.018
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.018
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.018
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.018
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.018
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.018
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.018
|
|
|
|
maintenance of apical basal cell polarity
|
GO:0035090 |
3 |
0.018
|
Fly |
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
11 |
0.018
|
|
|
|
response to epidermal growth factor
|
GO:0070849 |
4 |
0.017
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.017
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.017
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.017
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.017
|
Yeast Mouse Fly |
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.017
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.017
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.017
|
Mouse |
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.017
|
|
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.017
|
Mouse |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.017
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.017
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.017
|
Fly |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.017
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.017
|
Fly |
|
|
learning or memory
|
GO:0007611 |
148 |
0.017
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.017
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
17 |
0.017
|
|
|
|
maintenance of epithelial cell apical basal polarity
|
GO:0045199 |
2 |
0.016
|
Fly |
|
|
autophagy
|
GO:0006914 |
45 |
0.016
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.016
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.016
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.016
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.016
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.016
|
Mouse |
|
|
axon guidance
|
GO:0007411 |
141 |
0.016
|
Fly |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.016
|
Mouse |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.016
|
|
|
|
regulation of plasminogen activation
|
GO:0010755 |
4 |
0.016
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.016
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.016
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.016
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.016
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.016
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.015
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
31 |
0.015
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.015
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.015
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.015
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.015
|
Fly |
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.015
|
|
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.015
|
|
|
|
regulation of hepatocyte proliferation
|
GO:2000345 |
6 |
0.015
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.015
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.015
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.015
|
|
|
|
activation of cdc42 gtpase activity
|
GO:0032864 |
2 |
0.015
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.015
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.015
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.015
|
Fly |
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
18 |
0.015
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.015
|
Mouse |
|
|
positive regulation of heart rate by epinephrine
|
GO:0003065 |
1 |
0.015
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.015
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.015
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.015
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.015
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.014
|
|
|
|
chronological cell aging
|
GO:0001300 |
1 |
0.014
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.014
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.014
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.014
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.014
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.014
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.014
|
|
|
|
integrin biosynthetic process
|
GO:0045112 |
1 |
0.014
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.014
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.014
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.014
|
Worm |
|
|
regulation of neutrophil apoptotic process
|
GO:0033029 |
1 |
0.014
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.014
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.014
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.014
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.014
|
|
|
|
regulation of phospholipid biosynthetic process
|
GO:0071071 |
3 |
0.014
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.014
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.014
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.014
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.014
|
Mouse |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.014
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.013
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.013
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.013
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.013
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.013
|
Mouse |
|
|
chloride transmembrane transport
|
GO:1902476 |
24 |
0.013
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.013
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.013
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.013
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.013
|
Fly |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.013
|
|
|
|
negative regulation of hemostasis
|
GO:1900047 |
11 |
0.013
|
|
|
|
entry into host
|
GO:0044409 |
15 |
0.013
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.013
|
|
|
|
learning
|
GO:0007612 |
98 |
0.013
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.013
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.013
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.013
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.013
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.013
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.013
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.013
|
|
|
|
organelle fusion
|
GO:0048284 |
28 |
0.013
|
Yeast |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.013
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.013
|
Worm |
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.013
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.013
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.013
|
Fly |
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.013
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.013
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.013
|
Fly |
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.013
|
Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.013
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.013
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.013
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.013
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.013
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.013
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
31 |
0.013
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.013
|
Mouse |
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.013
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.013
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.013
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.012
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.012
|
Yeast |
|
|
response to uv a
|
GO:0070141 |
1 |
0.012
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.012
|
Mouse |
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
3 |
0.012
|
|
