Mus musculus

142 known processes

Aim2

absent in melanoma 2

(Aliases: Ifi210,Gm1313)

Aim2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pyroptosis GO:0070269 8 0.988
regulation of interleukin 10 secretion GO:2001179 4 0.986
cellular response to lipopolysaccharide GO:0071222 77 0.940
regulation of interleukin 1 alpha secretion GO:0050705 3 0.922
negative regulation of necrotic cell death GO:0060547 11 0.919
release of cytochrome c from mitochondria GO:0001836 23 0.887
positive regulation of interleukin 1 secretion GO:0050716 14 0.885
cellular response to molecule of bacterial origin GO:0071219 83 0.878
cellular response to biotic stimulus GO:0071216 92 0.857
positive regulation of release of cytochrome c from mitochondria GO:0090200 5 0.841
cellular response to lipid GO:0071396 145 0.793
interferon beta production GO:0032608 16 0.780
apoptotic dna fragmentation GO:0006309 7 0.734
regulation of interleukin 8 production GO:0032677 3 0.721
activation of immune response GO:0002253 138 0.720
interspecies interaction between organisms GO:0044419 83 0.700
defense response to other organism GO:0098542 197 0.698
positive regulation of interleukin 8 secretion GO:2000484 1 0.693
positive regulation of interleukin 6 secretion GO:2000778 1 0.688
immune effector process GO:0002252 321 0.672
regulation of defense response to virus GO:0050688 18 0.666
response to lipopolysaccharide GO:0032496 128 0.656
positive regulation of apoptotic signaling pathway GO:2001235 95 0.653
cellular response to cytokine stimulus GO:0071345 189 0.637
negative regulation of phosphorus metabolic process GO:0010563 184 0.636
negative regulation of protein metabolic process GO:0051248 282 0.612
type i interferon production GO:0032606 29 0.611
defense response to bacterium GO:0042742 119 0.607
apoptotic nuclear changes GO:0030262 9 0.600
response to molecule of bacterial origin GO:0002237 143 0.592
innate immune response GO:0045087 157 0.592
regulation of multi organism process GO:0043900 111 0.589
cellularization GO:0007349 1 0.586
negative regulation of cellular protein metabolic process GO:0032269 247 0.586
regulation of cell activation GO:0050865 289 0.570
negative regulation of necroptotic process GO:0060546 9 0.567
dna catabolic process endonucleolytic GO:0000737 15 0.567
positive regulation of innate immune response GO:0045089 80 0.565
interleukin 1 alpha secretion GO:0050703 3 0.547
negative regulation of phosphate metabolic process GO:0045936 184 0.542
negative regulation of phosphorylation GO:0042326 166 0.540
defense response to virus GO:0051607 68 0.538
apoptotic mitochondrial changes GO:0008637 48 0.528
positive regulation of interleukin 1 alpha production GO:0032730 4 0.511
defense response to protozoan GO:0042832 25 0.509
regulation of interleukin 8 secretion GO:2000482 2 0.497
negative regulation of activated t cell proliferation GO:0046007 7 0.496
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.496
defense response to gram positive bacterium GO:0050830 50 0.492
mitochondrion organization GO:0007005 134 0.481
regulation of cytokine production GO:0001817 266 0.468
interleukin 10 secretion GO:0072608 4 0.457
regulation of apoptotic dna fragmentation GO:1902510 5 0.455
positive regulation of chemokine secretion GO:0090197 4 0.451
regulation of protein localization GO:0032880 231 0.450
cellular nitrogen compound catabolic process GO:0044270 280 0.445
heterocycle catabolic process GO:0046700 280 0.445
regulation of defense response GO:0031347 233 0.444
regulation of protein complex assembly GO:0043254 83 0.423
response to endoplasmic reticulum stress GO:0034976 53 0.415
regulation of protein kinase activity GO:0045859 232 0.410
mitochondrial depolarization GO:0051882 6 0.408
activation of innate immune response GO:0002218 56 0.407
t cell proliferation GO:0042098 120 0.396
negative regulation of cytokine production GO:0001818 84 0.395
regulation of chemokine secretion GO:0090196 4 0.395
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 4 0.392
cytokine production GO:0001816 319 0.390
regulation of hydrolase activity GO:0051336 246 0.385
negative regulation of kinase activity GO:0033673 81 0.383
regulation of establishment of protein localization GO:0070201 181 0.379
positive regulation of interleukin 10 secretion GO:2001181 1 0.367
regulation of secretion GO:0051046 274 0.364
lymphocyte proliferation GO:0046651 164 0.359
regulation of necroptotic process GO:0060544 10 0.357
interleukin 1 secretion GO:0050701 16 0.347
organic cyclic compound catabolic process GO:1901361 295 0.345
interleukin 6 secretion GO:0072604 3 0.344
negative regulation of protein phosphorylation GO:0001933 126 0.343
myeloid cell differentiation GO:0030099 233 0.330
interleukin 1 production GO:0032612 31 0.326
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.322
negative regulation of transferase activity GO:0051348 85 0.311
rac protein signal transduction GO:0016601 13 0.310
extrinsic apoptotic signaling pathway GO:0097191 126 0.309
leukocyte proliferation GO:0070661 172 0.308
regulation of lymphocyte proliferation GO:0050670 117 0.308
regulation of activated t cell proliferation GO:0046006 16 0.303
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 3 0.302
protein modification by small protein conjugation or removal GO:0070647 207 0.302
cellular response to interferon gamma GO:0071346 25 0.301
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.300
regulation of interferon alpha production GO:0032647 5 0.295
compound eye development GO:0048749 1 0.294
immune response activating signal transduction GO:0002757 116 0.292
regulation of leukocyte proliferation GO:0070663 121 0.292
guanosine containing compound metabolic process GO:1901068 144 0.289
regulation of protein transport GO:0051223 163 0.286
regulation of kinase activity GO:0043549 249 0.286
negative regulation of protein modification process GO:0031400 163 0.284
glial cell apoptotic process GO:0034349 3 0.281
cellular response to dna damage stimulus GO:0006974 207 0.276
regulation of lymphocyte activation GO:0051249 240 0.276
glycosyl compound catabolic process GO:1901658 206 0.273
aromatic compound catabolic process GO:0019439 286 0.272
positive regulation of interleukin 8 production GO:0032757 2 0.266
positive regulation of cytokine secretion GO:0050715 41 0.262
dna metabolic process GO:0006259 303 0.260
regulation of defense response to virus by host GO:0050691 8 0.260
regulation of necrotic cell death GO:0010939 13 0.259
antibacterial peptide production GO:0002778 2 0.259
toxin transport GO:1901998 38 0.259
spermatid development GO:0007286 108 0.257
regulation of inflammatory response GO:0050727 147 0.256
positive regulation of interleukin 1 beta secretion GO:0050718 14 0.255
negative regulation of interferon beta production GO:0032688 3 0.252
cellular amino acid metabolic process GO:0006520 103 0.250
inflammatory response GO:0006954 244 0.248
response to protozoan GO:0001562 28 0.242
positive regulation of lymphocyte proliferation GO:0050671 70 0.241
protein secretion GO:0009306 111 0.241
leukocyte activation involved in immune response GO:0002366 126 0.240
positive regulation of cytokine production GO:0001819 174 0.240
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.240
positive regulation of programmed cell death GO:0043068 218 0.236
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.235
negative regulation of cell activation GO:0050866 111 0.234
establishment of protein localization to organelle GO:0072594 118 0.233
regulation of execution phase of apoptosis GO:1900117 9 0.232
regulation of actin filament length GO:0030832 45 0.227
myeloid dendritic cell activation involved in immune response GO:0002277 2 0.226
single organism nuclear import GO:1902593 95 0.226
necroptotic process GO:0070266 21 0.225
regulation of type i interferon production GO:0032479 22 0.225
regulation of transferase activity GO:0051338 263 0.224
antibacterial peptide biosynthetic process GO:0002780 2 0.219
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.217
i kappab kinase nf kappab signaling GO:0007249 85 0.216
positive regulation of defense response to bacterium GO:1900426 1 0.216
regulation of interleukin 1 production GO:0032652 26 0.212
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.211
sperm individualization GO:0007291 1 0.209
positive regulation of lymphocyte activation GO:0051251 140 0.208
regulation of defense response to bacterium GO:1900424 3 0.207
regulation of antibacterial peptide production GO:0002786 1 0.207
interleukin 1 beta secretion GO:0050702 16 0.206
membrane depolarization GO:0051899 64 0.205
purine ribonucleotide metabolic process GO:0009150 290 0.205
positive regulation of interleukin 1 production GO:0032732 17 0.204
leukocyte differentiation GO:0002521 342 0.203
intrinsic apoptotic signaling pathway GO:0097193 132 0.202
regulation of protein localization to nucleus GO:1900180 60 0.201
nucleoside triphosphate metabolic process GO:0009141 230 0.199
regulation of b cell activation GO:0050864 81 0.196
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.194
positive regulation of antimicrobial peptide production GO:0002225 1 0.193
cytoplasmic transport GO:0016482 234 0.193
regulation of protein targeting GO:1903533 61 0.192
nucleoside metabolic process GO:0009116 246 0.191
myeloid leukocyte activation GO:0002274 83 0.189
regulation of interleukin 1 alpha production GO:0032650 4 0.188
regulation of nucleotide catabolic process GO:0030811 122 0.188
rho protein signal transduction GO:0007266 32 0.186
positive regulation of protein transport GO:0051222 93 0.185
response to atp GO:0033198 8 0.183
spermatid differentiation GO:0048515 115 0.183
positive regulation of secretion GO:0051047 130 0.182
cellular component disassembly involved in execution phase of apoptosis GO:0006921 9 0.178
antimicrobial peptide production GO:0002775 2 0.177
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.176
germ cell development GO:0007281 185 0.173
regulation of stress activated mapk cascade GO:0032872 69 0.171
mapk cascade GO:0000165 281 0.169
epidermis development GO:0008544 187 0.168
regulation of intracellular protein transport GO:0033157 82 0.167
organophosphate catabolic process GO:0046434 232 0.167
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.166
nucleocytoplasmic transport GO:0006913 139 0.166
regulation of apoptotic signaling pathway GO:2001233 197 0.165
actin polymerization or depolymerization GO:0008154 54 0.164
myeloid cell activation involved in immune response GO:0002275 34 0.160
negative regulation of immune system process GO:0002683 209 0.160
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.157
positive regulation of cell death GO:0010942 224 0.157
negative regulation of intracellular protein transport GO:0090317 27 0.154
skin development GO:0043588 220 0.152
interleukin 1 beta production GO:0032611 30 0.150
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.147
membrane hyperpolarization GO:0060081 21 0.146
interleukin 8 secretion GO:0072606 3 0.145
purine containing compound catabolic process GO:0072523 213 0.145
regulation of response to biotic stimulus GO:0002831 38 0.144
nucleoside triphosphate catabolic process GO:0009143 205 0.144
circadian sleep wake cycle non rem sleep GO:0042748 2 0.143
regulation of interleukin 18 production GO:0032661 3 0.142
adaptive immune response GO:0002250 155 0.141
positive regulation of jnk cascade GO:0046330 46 0.140
regulation of response to wounding GO:1903034 189 0.139
protein processing GO:0016485 163 0.138
apoptotic signaling pathway GO:0097190 306 0.138
gtp metabolic process GO:0046039 144 0.137
ribonucleotide catabolic process GO:0009261 208 0.135
regulation of cell cycle GO:0051726 281 0.135
positive regulation of apoptotic process GO:0043065 217 0.134
positive regulation of stress activated mapk cascade GO:0032874 48 0.133
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.133
necrotic cell death GO:0070265 30 0.132
regulation of nucleoside metabolic process GO:0009118 130 0.131
tumor necrosis factor production GO:0032640 50 0.130
negative regulation of b cell proliferation GO:0030889 13 0.128
secondary metabolic process GO:0019748 18 0.124
lymphocyte migration GO:0072676 26 0.123
purine nucleoside triphosphate metabolic process GO:0009144 226 0.123
positive regulation of secretion by cell GO:1903532 114 0.122
developmental maturation GO:0021700 193 0.121
interferon beta biosynthetic process GO:0045350 4 0.120
jnk cascade GO:0007254 72 0.120
toll like receptor signaling pathway GO:0002224 38 0.118
positive regulation of mitochondrion organization GO:0010822 17 0.118
keratinocyte differentiation GO:0030216 48 0.115
purine nucleoside catabolic process GO:0006152 205 0.115
b cell proliferation GO:0042100 53 0.114
antimicrobial peptide biosynthetic process GO:0002777 2 0.114
negative regulation of cell cycle GO:0045786 123 0.113
positive regulation of interleukin 6 production GO:0032755 37 0.113
positive regulation of interleukin 1 beta production GO:0032731 16 0.112
epithelial tube morphogenesis GO:0060562 303 0.112
intestinal epithelial structure maintenance GO:0060729 4 0.112
positive regulation of immune effector process GO:0002699 107 0.110
nucleobase containing small molecule metabolic process GO:0055086 352 0.110
response to interleukin 1 GO:0070555 11 0.109
negative regulation of protein localization to nucleus GO:1900181 23 0.109
er nucleus signaling pathway GO:0006984 27 0.108
protein autoprocessing GO:0016540 2 0.108
homeostasis of number of cells GO:0048872 210 0.108
regulation of cellular ketone metabolic process GO:0010565 66 0.107
negative regulation of protein ubiquitination GO:0031397 19 0.107
endocytosis GO:0006897 168 0.106
cellular response to hormone stimulus GO:0032870 150 0.106
regulation of actin cytoskeleton organization GO:0032956 84 0.106
purine containing compound metabolic process GO:0072521 311 0.105
zymogen activation GO:0031638 41 0.103
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.103
protein localization to nucleus GO:0034504 121 0.103
thymocyte apoptotic process GO:0070242 19 0.103
positive regulation of actin filament polymerization GO:0030838 26 0.103
autophagy GO:0006914 45 0.102
regulation of intracellular transport GO:0032386 159 0.102
regulation of membrane potential GO:0042391 192 0.101
cellular amine metabolic process GO:0044106 44 0.099
t cell activation GO:0042110 289 0.099
regulation of gtp catabolic process GO:0033124 113 0.099
regulation of neuron death GO:1901214 134 0.099
pattern recognition receptor signaling pathway GO:0002221 47 0.098
cellular response to external stimulus GO:0071496 88 0.097
ras protein signal transduction GO:0007265 77 0.097
nucleoside catabolic process GO:0009164 206 0.095
spermatogenesis GO:0007283 284 0.095
regulation of cytoskeleton organization GO:0051493 122 0.095
male gamete generation GO:0048232 285 0.094
antibacterial humoral response GO:0019731 8 0.094
macromolecule catabolic process GO:0009057 281 0.093
negative regulation of cytoplasmic transport GO:1903650 29 0.093
cellular amide metabolic process GO:0043603 58 0.093
negative regulation of molecular function GO:0044092 258 0.093
positive regulation of t cell proliferation GO:0042102 52 0.092
regulation of cellular component size GO:0032535 121 0.092
negative regulation of leukocyte proliferation GO:0070664 46 0.091
regulation of t cell activation GO:0050863 170 0.091
negative regulation of lymphocyte activation GO:0051250 91 0.090
positive regulation of leukocyte proliferation GO:0070665 73 0.090
neural tube development GO:0021915 160 0.089
protein catabolic process GO:0030163 221 0.088
myeloid leukocyte differentiation GO:0002573 119 0.088
purine nucleotide catabolic process GO:0006195 211 0.088
positive regulation of hydrolase activity GO:0051345 148 0.087
regulation of cellular catabolic process GO:0031329 242 0.086
negative regulation of lymphocyte proliferation GO:0050672 45 0.086
positive regulation of interleukin 18 production GO:0032741 2 0.085
ribonucleoside catabolic process GO:0042454 206 0.085
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.085
regulation of tumor necrosis factor production GO:0032680 49 0.084
interferon alpha production GO:0032607 7 0.084
protein ubiquitination GO:0016567 171 0.083
positive regulation of antibacterial peptide production GO:0002803 1 0.083
regulation of actin polymerization or depolymerization GO:0008064 45 0.082
positive regulation of peptidase activity GO:0010952 49 0.082
positive regulation of t cell activation GO:0050870 101 0.082
protein localization to organelle GO:0033365 185 0.081
response to interferon gamma GO:0034341 34 0.081
protein modification by small protein conjugation GO:0032446 187 0.081
negative regulation of nik nf kappab signaling GO:1901223 2 0.081
cell type specific apoptotic process GO:0097285 268 0.080
negative regulation of protein import into nucleus GO:0042308 21 0.079
negative regulation of interferon alpha production GO:0032687 1 0.079
b cell activation GO:0042113 161 0.079
regulation of autophagy GO:0010506 30 0.079
rhythmic process GO:0048511 174 0.078
ribonucleoside triphosphate catabolic process GO:0009203 199 0.077
membrane organization GO:0061024 245 0.077
cellular response to organonitrogen compound GO:0071417 145 0.076
embryonic epithelial tube formation GO:0001838 130 0.076
regulation of nucleocytoplasmic transport GO:0046822 73 0.075
cellular response to corticosteroid stimulus GO:0071384 13 0.075
positive regulation of antimicrobial humoral response GO:0002760 2 0.074
leukocyte homeostasis GO:0001776 79 0.072
regulation of endopeptidase activity GO:0052548 89 0.072
interleukin 18 production GO:0032621 4 0.071
angiogenesis GO:0001525 201 0.070
phagocytosis GO:0006909 66 0.070
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.069
gtp catabolic process GO:0006184 143 0.069
regulation of t cell proliferation GO:0042129 92 0.069
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.068
defense response to gram negative bacterium GO:0050829 28 0.068
nucleotide metabolic process GO:0009117 332 0.068
regulation of interleukin 10 production GO:0032653 21 0.067
positive regulation of cellular component biogenesis GO:0044089 94 0.066
adhesion of symbiont to host GO:0044406 8 0.066
neural tube formation GO:0001841 108 0.065
wound healing GO:0042060 157 0.065
lung development GO:0030324 164 0.065
positive regulation of endopeptidase activity GO:0010950 43 0.064
regulation of jnk cascade GO:0046328 62 0.064
macropinocytosis GO:0044351 4 0.063
regulation of body fluid levels GO:0050878 162 0.062
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.062
erk1 and erk2 cascade GO:0070371 77 0.061
positive regulation of mapk cascade GO:0043410 170 0.061
regulation of organelle organization GO:0033043 289 0.061
regulation of nucleotide metabolic process GO:0006140 169 0.061
negative regulation of cell proliferation GO:0008285 296 0.060
cell activation involved in immune response GO:0002263 126 0.060
nucleoside phosphate metabolic process GO:0006753 338 0.060
respiratory tube development GO:0030323 167 0.059
regulation of interferon beta production GO:0032648 13 0.059
regulation of mapk cascade GO:0043408 248 0.059
engulfment of apoptotic cell GO:0043652 3 0.058
detection of molecule of bacterial origin GO:0032490 2 0.057
production of molecular mediator of immune response GO:0002440 103 0.057
protein oligomerization GO:0051259 67 0.057
positive regulation of proteolysis GO:0045862 85 0.057
organonitrogen compound catabolic process GO:1901565 264 0.056
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.055
regulation of interleukin 1 beta production GO:0032651 25 0.055
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.055
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.055
signal transduction in absence of ligand GO:0038034 55 0.054
nuclear import GO:0051170 95 0.054
regulation of cysteine type endopeptidase activity GO:2000116 65 0.054
response to light stimulus GO:0009416 135 0.054
pigment metabolic process GO:0042440 32 0.053
reactive oxygen species metabolic process GO:0072593 84 0.053
regulation of ras protein signal transduction GO:0046578 114 0.053
regulation of chemokine production GO:0032642 30 0.053
protein import into nucleus GO:0006606 95 0.053
purine ribonucleoside metabolic process GO:0046128 241 0.052
cell maturation GO:0048469 127 0.052
regulation of secretion by cell GO:1903530 249 0.051
female gamete generation GO:0007292 74 0.051
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.051
regulation of cytoplasmic transport GO:1903649 112 0.051
cellular response to glucocorticoid stimulus GO:0071385 13 0.050
regulation of cellular response to stress GO:0080135 159 0.050
regulation of protein serine threonine kinase activity GO:0071900 157 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.049
small gtpase mediated signal transduction GO:0007264 97 0.049
response to uv GO:0009411 44 0.049
regulation of response to cytokine stimulus GO:0060759 23 0.048
response to peptide GO:1901652 136 0.048
protein maturation GO:0051604 176 0.048
lymphocyte homeostasis GO:0002260 64 0.048
cellular response to topologically incorrect protein GO:0035967 25 0.048
tube formation GO:0035148 140 0.048
purine ribonucleoside catabolic process GO:0046130 205 0.048
digestive tract development GO:0048565 190 0.048
response to dexamethasone GO:0071548 8 0.047
regulation of hormone levels GO:0010817 211 0.047
response to organonitrogen compound GO:0010243 246 0.047
phenol containing compound metabolic process GO:0018958 60 0.047
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
protein import GO:0017038 101 0.046
positive regulation of protein secretion GO:0050714 52 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.046
hematopoietic progenitor cell differentiation GO:0002244 143 0.046
amine metabolic process GO:0009308 45 0.046
reactive oxygen species biosynthetic process GO:1903409 8 0.045
response to purine containing compound GO:0014074 28 0.045
nucleotide catabolic process GO:0009166 217 0.045
regulation of cytokine secretion GO:0050707 61 0.044
cytokine secretion GO:0050663 72 0.044
regulation of interleukin 6 production GO:0032675 55 0.044
positive regulation of protein complex assembly GO:0031334 45 0.044
cognition GO:0050890 149 0.044
neuron apoptotic process GO:0051402 142 0.043
actin filament polymerization GO:0030041 44 0.043
protein heterooligomerization GO:0051291 14 0.043
morphogenesis of embryonic epithelium GO:0016331 159 0.042
response to drug GO:0042493 75 0.042
nuclear transport GO:0051169 139 0.042
peripheral nervous system development GO:0007422 53 0.041
regulation of circadian sleep wake cycle GO:0042749 3 0.041
cellular ketone metabolic process GO:0042180 84 0.041
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.041
macrophage differentiation GO:0030225 20 0.040
chemokine production GO:0032602 34 0.040
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.040
peptide metabolic process GO:0006518 46 0.040
neuron death GO:0070997 154 0.040
apoptotic process involved in development GO:1902742 28 0.040
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.039
interleukin 1 alpha production GO:0032610 5 0.039
regulation of cell migration GO:0030334 219 0.039
regulation of rac protein signal transduction GO:0035020 19 0.039
regulation of b cell proliferation GO:0030888 39 0.039
syncytium formation GO:0006949 43 0.039
purine ribonucleotide catabolic process GO:0009154 208 0.039
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.039
posttranscriptional regulation of gene expression GO:0010608 155 0.039
stress activated protein kinase signaling cascade GO:0031098 81 0.038
positive regulation of protein phosphorylation GO:0001934 242 0.038
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
lymphocyte apoptotic process GO:0070227 54 0.038
response to organophosphorus GO:0046683 22 0.037
intracellular protein transport GO:0006886 204 0.037
negative regulation of t cell activation GO:0050868 65 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
regulation of ras gtpase activity GO:0032318 88 0.037
regulation of endocytosis GO:0030100 69 0.037
ribonucleoside metabolic process GO:0009119 245 0.037
peptide transport GO:0015833 133 0.037
ribose phosphate metabolic process GO:0019693 291 0.036
g protein coupled receptor signaling pathway GO:0007186 243 0.036
peripheral nervous system neuron differentiation GO:0048934 9 0.036
purine nucleoside metabolic process GO:0042278 241 0.036
regulation of t cell apoptotic process GO:0070232 28 0.036
interleukin 6 production GO:0032635 58 0.036
peripheral nervous system neuron development GO:0048935 9 0.035
negative regulation of mapk cascade GO:0043409 65 0.035
regulation of thymocyte apoptotic process GO:0070243 14 0.035
gland development GO:0048732 330 0.035
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.034
regulation of peptidase activity GO:0052547 96 0.034
positive regulation of protein modification process GO:0031401 299 0.034
t cell homeostasis GO:0043029 35 0.033
peptide biosynthetic process GO:0043043 11 0.033
circadian sleep wake cycle GO:0042745 5 0.033
pinocytosis GO:0006907 6 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.033
cellular response to peptidoglycan GO:0071224 4 0.033
regulation of antimicrobial humoral response GO:0002759 3 0.033
positive regulation of interferon gamma production GO:0032729 39 0.033
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.033
growth of symbiont in host GO:0044117 23 0.033
negative regulation of growth GO:0045926 99 0.032
regulation of protein ubiquitination GO:0031396 52 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
sensory perception of mechanical stimulus GO:0050954 107 0.032
lymphocyte activation involved in immune response GO:0002285 93 0.032
stress activated mapk cascade GO:0051403 80 0.032
actin filament organization GO:0007015 113 0.032
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 6 0.032
response to organic cyclic compound GO:0014070 198 0.032
cellular response to organic cyclic compound GO:0071407 87 0.031
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 6 0.031
antigen processing and presentation of peptide antigen GO:0048002 29 0.031
response to oxygen levels GO:0070482 62 0.031
neuron maturation GO:0042551 29 0.031
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.031
regulation of adaptive immune response GO:0002819 90 0.031
myeloid dendritic cell activation GO:0001773 25 0.030
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.030
regulation of cellular component biogenesis GO:0044087 181 0.030
positive regulation of kinase activity GO:0033674 155 0.030
interleukin 8 production GO:0032637 4 0.030
muscle cell differentiation GO:0042692 261 0.030
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.029
cellular response to abiotic stimulus GO:0071214 56 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
cell fate commitment GO:0045165 210 0.029
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
reactive nitrogen species metabolic process GO:2001057 0 0.028
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 17 0.028
positive regulation of cell adhesion GO:0045785 80 0.028
sensory perception of sound GO:0007605 97 0.028
response to bacterial lipopeptide GO:0070339 3 0.028
regulation of vesicle mediated transport GO:0060627 139 0.028
programmed necrotic cell death GO:0097300 28 0.028
regulation of leukocyte differentiation GO:1902105 159 0.028
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.028
cellular protein complex assembly GO:0043623 116 0.027
signal transduction by p53 class mediator GO:0072331 51 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
regulation of leukocyte apoptotic process GO:2000106 56 0.027
immune response regulating signaling pathway GO:0002764 125 0.027
transmembrane transport GO:0055085 412 0.027
negative regulation of b cell activation GO:0050869 27 0.027

Aim2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org