Mus musculus

16 known processes

Adam3

a disintegrin and metallopeptidase domain 3 (cyritestin)

(Aliases: tMDC,Taz83,Cyrn1,MGC150317)

Adam3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.125
regulation of cellular amino acid metabolic process GO:0006521 5 0.121
response to organonitrogen compound GO:0010243 246 0.117
cellular amine metabolic process GO:0044106 44 0.115
regulation of hormone levels GO:0010817 211 0.097
regulation of cellular amine metabolic process GO:0033238 20 0.096
olfactory learning GO:0008355 2 0.088
response to testosterone GO:0033574 3 0.083
regulation of cell cycle GO:0051726 281 0.078
multicellular organismal homeostasis GO:0048871 164 0.074
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.068
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.066
regulation of cellular ketone metabolic process GO:0010565 66 0.065
peptide transport GO:0015833 133 0.063
insulin secretion GO:0030073 89 0.063
prevention of polyspermy GO:0060468 4 0.058
Mouse
cell cell recognition GO:0009988 44 0.058
peptide hormone secretion GO:0030072 109 0.057
negative regulation of immune system process GO:0002683 209 0.054
response to peptide hormone GO:0043434 127 0.054
amine metabolic process GO:0009308 45 0.053
single fertilization GO:0007338 82 0.053
response to peptide GO:1901652 136 0.050
neural precursor cell proliferation GO:0061351 121 0.049
cell type specific apoptotic process GO:0097285 268 0.049
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.048
hormone secretion GO:0046879 128 0.048
regulation of cellular catabolic process GO:0031329 242 0.046
Mouse
regulation of hormone secretion GO:0046883 88 0.045
g protein coupled receptor signaling pathway GO:0007186 243 0.045
positive regulation of cell development GO:0010720 237 0.045
anatomical structure homeostasis GO:0060249 145 0.042
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.042
regulation of mapk cascade GO:0043408 248 0.042
Mouse
spermatid differentiation GO:0048515 115 0.041
progesterone metabolic process GO:0042448 4 0.040
positive regulation of cell cycle process GO:0090068 61 0.039
oxidation reduction process GO:0055114 342 0.039
regulation of neuron differentiation GO:0045664 281 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
anion transport GO:0006820 177 0.038
peptidyl amino acid modification GO:0018193 336 0.037
male gamete generation GO:0048232 285 0.037
renal system development GO:0072001 225 0.037
forebrain development GO:0030900 302 0.037
regulation of cell cycle process GO:0010564 160 0.036
negative regulation of phosphorylation GO:0042326 166 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
axonogenesis GO:0007409 274 0.036
binding of sperm to zona pellucida GO:0007339 34 0.035
negative regulation of intracellular signal transduction GO:1902532 167 0.035
negative regulation of protein modification process GO:0031400 163 0.035
regulation of anatomical structure size GO:0090066 178 0.034
pigment metabolic process GO:0042440 32 0.034
sensory perception GO:0007600 245 0.033
cellular amino acid metabolic process GO:0006520 103 0.033
cation transport GO:0006812 399 0.031
positive regulation of protein modification process GO:0031401 299 0.031
Mouse
fat cell differentiation GO:0045444 160 0.031
positive regulation of cell cycle GO:0045787 92 0.030
synaptic transmission GO:0007268 329 0.030
negative regulation of nervous system development GO:0051961 156 0.030
tissue homeostasis GO:0001894 115 0.030
Mouse
nitrogen compound transport GO:0071705 271 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
small molecule biosynthetic process GO:0044283 132 0.030
monocarboxylic acid metabolic process GO:0032787 191 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
peptide secretion GO:0002790 114 0.028
cofactor metabolic process GO:0051186 80 0.028
positive regulation of keratinocyte proliferation GO:0010838 4 0.028
positive regulation of protein kinase b signaling GO:0051897 32 0.028
Mouse
activation of immune response GO:0002253 138 0.028
Mouse
second messenger mediated signaling GO:0019932 73 0.028
exocytosis GO:0006887 121 0.028
action potential GO:0001508 78 0.028
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.028
amide transport GO:0042886 138 0.028
organic hydroxy compound metabolic process GO:1901615 203 0.028
regulation of neuron apoptotic process GO:0043523 122 0.027
Mouse
germ cell development GO:0007281 185 0.027
determination of left right symmetry GO:0007368 80 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
histone modification GO:0016570 159 0.027
myeloid cell differentiation GO:0030099 233 0.027
regulation of mitotic cell cycle GO:0007346 126 0.027
homeostasis of number of cells GO:0048872 210 0.027
Mouse
telencephalon development GO:0021537 186 0.026
ion transmembrane transport GO:0034220 361 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
associative learning GO:0008306 61 0.025
Mouse
epidermis development GO:0008544 187 0.025
response to organic cyclic compound GO:0014070 198 0.024
Mouse
gliogenesis GO:0042063 141 0.024
Mouse
regulation of lymphocyte activation GO:0051249 240 0.024
Mouse
heart morphogenesis GO:0003007 178 0.024
Mouse
regulation of blood pressure GO:0008217 93 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
carbohydrate homeostasis GO:0033500 128 0.023
regulation of secretion GO:0051046 274 0.023
positive regulation of transferase activity GO:0051347 167 0.023
Mouse
epithelial tube morphogenesis GO:0060562 303 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
cell growth GO:0016049 130 0.023
negative regulation of cell development GO:0010721 169 0.023
neuron death GO:0070997 154 0.023
Mouse
transmembrane transport GO:0055085 412 0.022
digestive tract development GO:0048565 190 0.022
protein kinase b signaling GO:0043491 74 0.022
Mouse
intracellular protein transport GO:0006886 204 0.022
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.021
cellular homeostasis GO:0019725 240 0.021
fertilization GO:0009566 127 0.021
regulation of organelle organization GO:0033043 289 0.021
carbohydrate metabolic process GO:0005975 230 0.021
ear development GO:0043583 200 0.021
neuron apoptotic process GO:0051402 142 0.021
Mouse
leukocyte differentiation GO:0002521 342 0.021
Mouse
meiotic cell cycle GO:0051321 122 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
cerebral cortex development GO:0021987 86 0.020
regulation of multi organism process GO:0043900 111 0.020
Mouse
multicellular organism growth GO:0035264 161 0.020
dna metabolic process GO:0006259 303 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
regulation of histone modification GO:0031056 56 0.020
regulation of kinase activity GO:0043549 249 0.020
Mouse
phospholipid metabolic process GO:0006644 87 0.020
cell adhesion GO:0007155 329 0.020
Mouse
negative regulation of neuron death GO:1901215 98 0.020
Mouse
l amino acid transport GO:0015807 32 0.020
cellular response to glucose stimulus GO:0071333 45 0.020
gland development GO:0048732 330 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
calcium mediated signaling GO:0019722 46 0.019
negative regulation of cell cycle GO:0045786 123 0.019
regulation of fat cell differentiation GO:0045598 81 0.019
circadian rhythm GO:0007623 114 0.019
glial cell differentiation GO:0010001 131 0.019
Mouse
endodermal cell fate specification GO:0001714 4 0.019
astrocyte fate commitment GO:0060018 4 0.019
covalent chromatin modification GO:0016569 163 0.019
negative regulation of growth GO:0045926 99 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.019
regulation of interleukin 5 secretion GO:2000662 2 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
multicellular organismal signaling GO:0035637 91 0.018
Mouse
pigmentation GO:0043473 71 0.018
cation transmembrane transport GO:0098655 266 0.018
learning GO:0007612 98 0.018
Mouse
regulation of cell motility GO:2000145 236 0.018
Mouse
mapk cascade GO:0000165 281 0.018
Mouse
purine nucleotide metabolic process GO:0006163 302 0.018
response to insulin GO:0032868 100 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.018
Mouse
response to drug GO:0042493 75 0.018
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
kidney development GO:0001822 213 0.018
regulation of membrane potential GO:0042391 192 0.018
Mouse
neuronal action potential GO:0019228 54 0.018
Mouse
positive regulation of homeostatic process GO:0032846 64 0.017
Mouse
erk1 and erk2 cascade GO:0070371 77 0.017
nucleoside metabolic process GO:0009116 246 0.017
humoral immune response GO:0006959 57 0.017
cellular response to acid chemical GO:0071229 68 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
Mouse
response to monosaccharide GO:0034284 67 0.017
spermatid development GO:0007286 108 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
chromatin organization GO:0006325 206 0.017
neuromuscular process GO:0050905 99 0.017
sperm egg recognition GO:0035036 37 0.017
organelle fission GO:0048285 170 0.017
positive regulation of nervous system development GO:0051962 221 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
Mouse
temperature homeostasis GO:0001659 26 0.017
positive regulation of protein catabolic process GO:0045732 60 0.017
Mouse
regulation of cellular component size GO:0032535 121 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.016
stem cell differentiation GO:0048863 268 0.016
Mouse
carboxylic acid transport GO:0046942 100 0.016
germ line sex determination GO:0018992 3 0.016
cell maturation GO:0048469 127 0.016
regulation of neuron death GO:1901214 134 0.016
Mouse
response to steroid hormone GO:0048545 56 0.016
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.016
learning or memory GO:0007611 148 0.016
Mouse
cell division GO:0051301 120 0.016
response to histamine GO:0034776 1 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
Mouse
developmental maturation GO:0021700 193 0.016
cellular response to lipid GO:0071396 145 0.016
multicellular organismal response to stress GO:0033555 62 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
Mouse
compound eye development GO:0048749 1 0.016
spermatogenesis GO:0007283 284 0.016
cellular response to external stimulus GO:0071496 88 0.016
feeding behavior GO:0007631 62 0.016
regulation of b cell activation GO:0050864 81 0.015
sclerotome development GO:0061056 4 0.015
lymphocyte activation involved in immune response GO:0002285 93 0.015
pigment biosynthetic process GO:0046148 26 0.015
rna processing GO:0006396 105 0.015
phenol containing compound biosynthetic process GO:0046189 21 0.015
negative regulation of interleukin 13 production GO:0032696 2 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
Mouse
wnt signaling pathway GO:0016055 188 0.015
response to acid chemical GO:0001101 111 0.015
regulation of peptide transport GO:0090087 91 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
locomotory behavior GO:0007626 195 0.015
Mouse
regulation of cell activation GO:0050865 289 0.015
Mouse
regulation of lipid metabolic process GO:0019216 118 0.015
formation of primary germ layer GO:0001704 77 0.015
stem cell development GO:0048864 219 0.015
Mouse
lipid biosynthetic process GO:0008610 179 0.015
insulin receptor signaling pathway GO:0008286 49 0.015
glycoprotein metabolic process GO:0009100 116 0.015
regulation of system process GO:0044057 200 0.015
epithelial cell development GO:0002064 159 0.014
male meiosis GO:0007140 37 0.014
positive regulation of secretion GO:0051047 130 0.014
regulation of nuclear division GO:0051783 56 0.014
negative regulation of lymphocyte activation GO:0051250 91 0.014
histone methylation GO:0016571 71 0.014
ribonucleotide biosynthetic process GO:0009260 59 0.014
regulation of chromosome organization GO:0033044 83 0.014
neural tube development GO:0021915 160 0.014
single organism nuclear import GO:1902593 95 0.014
protein targeting GO:0006605 143 0.014
regulation of secretion by cell GO:1903530 249 0.014
cardiac muscle contraction GO:0060048 32 0.014
cellular response to carbohydrate stimulus GO:0071322 50 0.014
regulation of interleukin 13 secretion GO:2000665 2 0.014
nucleotide metabolic process GO:0009117 332 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
cognition GO:0050890 149 0.014
Mouse
aromatic compound catabolic process GO:0019439 286 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
alcohol metabolic process GO:0006066 116 0.014
blood circulation GO:0008015 195 0.013
protein localization to organelle GO:0033365 185 0.013
muscle system process GO:0003012 141 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
intestinal epithelial structure maintenance GO:0060729 4 0.013
negative regulation of t cell cytokine production GO:0002725 1 0.013
neuron projection guidance GO:0097485 141 0.013
glucose homeostasis GO:0042593 128 0.013
nuclear division GO:0000280 158 0.013
cyclic nucleotide biosynthetic process GO:0009190 44 0.013
immune effector process GO:0002252 321 0.013
cyclic purine nucleotide metabolic process GO:0052652 43 0.013
mitochondrion organization GO:0007005 134 0.013
regulation of cell division GO:0051302 76 0.013
viral process GO:0016032 41 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
muscle tissue development GO:0060537 308 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
protein localization to nucleus GO:0034504 121 0.012
regulation of saliva secretion GO:0046877 2 0.012
mitotic cell cycle GO:0000278 195 0.012
cellular response to peptide GO:1901653 92 0.012
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.012
cell fate commitment GO:0045165 210 0.012
regulation of defense response GO:0031347 233 0.012
Mouse
vitamin d biosynthetic process GO:0042368 3 0.012
anion transmembrane transport GO:0098656 71 0.012
regulation of erk1 and erk2 cascade GO:0070372 71 0.012
organic acid transport GO:0015849 101 0.012
astrocyte differentiation GO:0048708 43 0.012
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
carbohydrate transport GO:0008643 62 0.012
negative regulation of keratinocyte differentiation GO:0045617 4 0.012
purine containing compound catabolic process GO:0072523 213 0.012
urogenital system development GO:0001655 261 0.012
cardiocyte differentiation GO:0035051 87 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
regulation of body fluid levels GO:0050878 162 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
Mouse
regulation of chromatin organization GO:1902275 57 0.012
positive regulation of growth GO:0045927 104 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
pancreatic pp cell fate commitment GO:0003329 2 0.012
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
respiratory gaseous exchange GO:0007585 43 0.012
gonad development GO:0008406 141 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
bmp signaling pathway GO:0030509 93 0.011
negative regulation of glial cell proliferation GO:0060253 4 0.011
cellular glucose homeostasis GO:0001678 52 0.011
hexose transport GO:0008645 56 0.011
chromatin modification GO:0016568 187 0.011
c21 steroid hormone biosynthetic process GO:0006700 3 0.011
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
Mouse
mitral valve development GO:0003174 4 0.011
calcitriol biosynthetic process from calciol GO:0036378 3 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
microtubule based process GO:0007017 236 0.011
membrane organization GO:0061024 245 0.011
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.011
mesenchymal cell development GO:0014031 93 0.011
Mouse
glucose import GO:0046323 32 0.011
toxin transport GO:1901998 38 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of transmembrane transport GO:0034762 128 0.011
gastrulation GO:0007369 116 0.011
response to nutrient levels GO:0031667 109 0.011
negative regulation of cell motility GO:2000146 61 0.011
cellular response to gonadotropin stimulus GO:0071371 4 0.011
hexose metabolic process GO:0019318 98 0.011
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
negative regulation of interleukin 5 production GO:0032714 4 0.011
divalent inorganic cation transport GO:0072511 178 0.011
negative regulation of t cell activation GO:0050868 65 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
Mouse
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
rhythmic process GO:0048511 174 0.011
response to follicle stimulating hormone GO:0032354 1 0.011
connective tissue development GO:0061448 179 0.011
protein import into nucleus GO:0006606 95 0.011
cellular alcohol metabolic process GO:0044107 3 0.011
rna interference GO:0016246 2 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
cardiac muscle tissue development GO:0048738 130 0.010
metanephric nephron tubule formation GO:0072289 4 0.010
body fluid secretion GO:0007589 53 0.010
regulation of voltage gated calcium channel activity GO:1901385 4 0.010
regulation of peptide hormone secretion GO:0090276 75 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
endocrine process GO:0050886 39 0.010
regulation of homeostatic process GO:0032844 182 0.010
Mouse
purine containing compound metabolic process GO:0072521 311 0.010
regulation of neural retina development GO:0061074 3 0.010
cell activation involved in immune response GO:0002263 126 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
organophosphate catabolic process GO:0046434 232 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
mesoderm morphogenesis GO:0048332 64 0.010
regulation of gliogenesis GO:0014013 50 0.010
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.010
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.010
protein methylation GO:0006479 81 0.010
pancreatic a cell fate commitment GO:0003326 2 0.010

Adam3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028
inherited metabolic disorder DOID:655 0 0.028
bone disease DOID:0080001 0 0.015
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015