Mus musculus

11 known processes

Txndc2

thioredoxin domain containing 2 (spermatozoa)

(Aliases: Sptrx-1,AU021712,Trx4,Sptrx1)

Txndc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.078
cellular amino acid metabolic process GO:0006520 103 0.061
spermatogenesis GO:0007283 284 0.058
lipid biosynthetic process GO:0008610 179 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.042
response to peptide hormone GO:0043434 127 0.040
male gamete generation GO:0048232 285 0.040
cellular amine metabolic process GO:0044106 44 0.039
amine metabolic process GO:0009308 45 0.037
peptidyl amino acid modification GO:0018193 336 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
organic hydroxy compound metabolic process GO:1901615 203 0.032
urogenital system development GO:0001655 261 0.030
response to peptide GO:1901652 136 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
cellular lipid metabolic process GO:0044255 323 0.028
germ cell development GO:0007281 185 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.026
development of primary sexual characteristics GO:0045137 143 0.025
cellular response to extracellular stimulus GO:0031668 81 0.025
positive regulation of mapk cascade GO:0043410 170 0.025
mapk cascade GO:0000165 281 0.025
oxidation reduction process GO:0055114 342 0.024
Human
sensory perception GO:0007600 245 0.024
rhythmic process GO:0048511 174 0.024
regulation of organelle organization GO:0033043 289 0.023
dna metabolic process GO:0006259 303 0.023
regulation of hormone levels GO:0010817 211 0.023
cellular homeostasis GO:0019725 240 0.022
regulation of mapk cascade GO:0043408 248 0.022
lipid transport GO:0006869 98 0.021
response to testosterone GO:0033574 3 0.021
heart morphogenesis GO:0003007 178 0.021
protein catabolic process GO:0030163 221 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
regulation of protein kinase activity GO:0045859 232 0.020
positive regulation of protein modification process GO:0031401 299 0.020
response to nutrient levels GO:0031667 109 0.020
mitotic cell cycle GO:0000278 195 0.020
kidney development GO:0001822 213 0.020
membrane organization GO:0061024 245 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.019
multi multicellular organism process GO:0044706 109 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
apoptotic signaling pathway GO:0097190 306 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
spermatid differentiation GO:0048515 115 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
fertilization GO:0009566 127 0.019
camera type eye development GO:0043010 266 0.019
cellular response to lipid GO:0071396 145 0.019
regulation of cell cycle GO:0051726 281 0.019
cellular response to cytokine stimulus GO:0071345 189 0.018
gonad development GO:0008406 141 0.018
immune effector process GO:0002252 321 0.018
intracellular protein transport GO:0006886 204 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
macromolecule catabolic process GO:0009057 281 0.018
lipid localization GO:0010876 126 0.018
steroid metabolic process GO:0008202 119 0.018
response to acid chemical GO:0001101 111 0.018
protein maturation GO:0051604 176 0.018
tissue homeostasis GO:0001894 115 0.017
nucleotide metabolic process GO:0009117 332 0.017
female gonad development GO:0008585 71 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
skin development GO:0043588 220 0.017
purine containing compound metabolic process GO:0072521 311 0.017
transmembrane transport GO:0055085 412 0.017
cell adhesion GO:0007155 329 0.016
response to organonitrogen compound GO:0010243 246 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
inflammatory response GO:0006954 244 0.016
response to extracellular stimulus GO:0009991 127 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
regulation of neuron differentiation GO:0045664 281 0.016
positive regulation of transferase activity GO:0051347 167 0.016
multicellular organism growth GO:0035264 161 0.016
female sex differentiation GO:0046660 84 0.016
regulation of anatomical structure size GO:0090066 178 0.016
cellular response to peptide GO:1901653 92 0.016
sperm motility GO:0030317 47 0.016
hormone metabolic process GO:0042445 86 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.015
regulation of protein kinase b signaling GO:0051896 56 0.015
monosaccharide metabolic process GO:0005996 106 0.015
negative regulation of nervous system development GO:0051961 156 0.015
maintenance of location GO:0051235 89 0.015
carbohydrate homeostasis GO:0033500 128 0.015
glycerolipid metabolic process GO:0046486 122 0.015
response to organic cyclic compound GO:0014070 198 0.015
organophosphate catabolic process GO:0046434 232 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
carbohydrate metabolic process GO:0005975 230 0.014
purine containing compound catabolic process GO:0072523 213 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
homeostasis of number of cells GO:0048872 210 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
nucleoside metabolic process GO:0009116 246 0.014
insulin secretion GO:0030073 89 0.014
innate immune response GO:0045087 157 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
protein processing GO:0016485 163 0.014
protein kinase b signaling GO:0043491 74 0.014
regulation of protein processing GO:0070613 96 0.014
cation transmembrane transport GO:0098655 266 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
cellular response to external stimulus GO:0071496 88 0.014
negative regulation of molecular function GO:0044092 258 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
lung development GO:0030324 164 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
regulation of homeostatic process GO:0032844 182 0.013
nitrogen compound transport GO:0071705 271 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
regulation of cell adhesion GO:0030155 154 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
microtubule based process GO:0007017 236 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
negative regulation of defense response GO:0031348 77 0.013
epidermis development GO:0008544 187 0.013
stem cell development GO:0048864 219 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
axonogenesis GO:0007409 274 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
mitotic cell cycle process GO:1903047 159 0.012
divalent metal ion transport GO:0070838 172 0.012
nucleoside catabolic process GO:0009164 206 0.012
regulation of protein maturation GO:1903317 96 0.012
mrna metabolic process GO:0016071 84 0.012
epithelial cell development GO:0002064 159 0.012
nuclear division GO:0000280 158 0.012
regulation of intracellular transport GO:0032386 159 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
renal system development GO:0072001 225 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
establishment of organelle localization GO:0051656 122 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
regulation of cell cycle process GO:0010564 160 0.012
respiratory system development GO:0060541 190 0.012
cellular chemical homeostasis GO:0055082 215 0.012
negative regulation of immune system process GO:0002683 209 0.012
wnt signaling pathway GO:0016055 188 0.012
extracellular matrix organization GO:0030198 147 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
response to monosaccharide GO:0034284 67 0.012
meiotic nuclear division GO:0007126 115 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
cognition GO:0050890 149 0.011
nucleotide catabolic process GO:0009166 217 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of protein localization GO:0032880 231 0.011
protein localization to organelle GO:0033365 185 0.011
chromatin organization GO:0006325 206 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
single organism cell adhesion GO:0098602 156 0.011
anion transport GO:0006820 177 0.011
rna processing GO:0006396 105 0.011
macromolecule methylation GO:0043414 120 0.011
endocytosis GO:0006897 168 0.011
glucose homeostasis GO:0042593 128 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
cell type specific apoptotic process GO:0097285 268 0.011
regulation of proteolysis GO:0030162 164 0.011
organic acid transport GO:0015849 101 0.011
defense response to other organism GO:0098542 197 0.011
circulatory system process GO:0003013 197 0.011
cellular response to testosterone stimulus GO:0071394 1 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
glycoprotein metabolic process GO:0009100 116 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
positive regulation of cell death GO:0010942 224 0.011
mesodermal cell migration GO:0008078 4 0.011
protein ubiquitination GO:0016567 171 0.011
peptide transport GO:0015833 133 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
cation transport GO:0006812 399 0.011
regulation of ion transport GO:0043269 215 0.011
myeloid cell differentiation GO:0030099 233 0.011
chromatin modification GO:0016568 187 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
locomotory behavior GO:0007626 195 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
cytokine production GO:0001816 319 0.011
heterocycle catabolic process GO:0046700 280 0.011
regulation of defense response GO:0031347 233 0.010
adult behavior GO:0030534 135 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
negative regulation of cell cycle GO:0045786 123 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
cellular response to starvation GO:0009267 57 0.010
muscle tissue development GO:0060537 308 0.010
tissue remodeling GO:0048771 102 0.010
protein localization to nucleus GO:0034504 121 0.010
gliogenesis GO:0042063 141 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
organelle localization GO:0051640 179 0.010
response to inorganic substance GO:0010035 96 0.010
response to starvation GO:0042594 65 0.010
monocarboxylic acid transport GO:0015718 44 0.010
ear development GO:0043583 200 0.010
cellular response to nutrient levels GO:0031669 64 0.010
anatomical structure homeostasis GO:0060249 145 0.010

Txndc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.014
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010