Mus musculus

51 known processes

Pdcd1lg2

programmed cell death 1 ligand 2

(Aliases: F730015O22Rik,PD-L2,MGC124039,Btdc,MGC124040,B7-DC)

Pdcd1lg2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of defense response GO:0031347 233 0.861
Mouse
defense response to other organism GO:0098542 197 0.784
Mouse
regulation of innate immune response GO:0045088 91 0.744
Mouse
cytokine production GO:0001816 319 0.727
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.605
cytokine secretion GO:0050663 72 0.592
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.584
response to molecule of bacterial origin GO:0002237 143 0.576
adaptive immune response GO:0002250 155 0.563
immune effector process GO:0002252 321 0.548
Mouse
regulation of cytokine production GO:0001817 266 0.521
Mouse
lymphocyte differentiation GO:0030098 242 0.510
Mouse
regulation of secretion GO:0051046 274 0.495
Mouse
inflammatory response GO:0006954 244 0.494
Mouse
regulation of cell activation GO:0050865 289 0.479
positive regulation of defense response GO:0031349 124 0.478
Mouse
regulation of inflammatory response GO:0050727 147 0.456
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.440
leukocyte mediated immunity GO:0002443 174 0.437
leukocyte activation involved in immune response GO:0002366 126 0.423
t cell proliferation GO:0042098 120 0.419
immune response activating signal transduction GO:0002757 116 0.417
Mouse
t cell activation GO:0042110 289 0.409
response to lipopolysaccharide GO:0032496 128 0.396
regulation of protein secretion GO:0050708 82 0.377
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.370
positive regulation of secretion GO:0051047 130 0.368
Mouse
cytokine production involved in immune response GO:0002367 34 0.365
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.356
lymphocyte proliferation GO:0046651 164 0.347
interleukin 12 secretion GO:0072610 3 0.337
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.333
positive regulation of cell activation GO:0050867 158 0.324
cellular amino acid metabolic process GO:0006520 103 0.319
regulation of leukocyte mediated immunity GO:0002703 104 0.318
regulation of cytokine secretion GO:0050707 61 0.314
Mouse
t cell differentiation GO:0030217 174 0.304
Mouse
regulation of t cell activation GO:0050863 170 0.296
production of molecular mediator of immune response GO:0002440 103 0.291
cell activation involved in immune response GO:0002263 126 0.283
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.280
Mouse
negative regulation of immune system process GO:0002683 209 0.271
leukocyte differentiation GO:0002521 342 0.263
Mouse
regulation of protein localization GO:0032880 231 0.262
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.256
regulation of cellular amine metabolic process GO:0033238 20 0.251
regulation of secretion by cell GO:1903530 249 0.250
Mouse
cellular response to biotic stimulus GO:0071216 92 0.243
regulation of leukocyte differentiation GO:1902105 159 0.242
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.242
leukocyte proliferation GO:0070661 172 0.238
positive regulation of t cell activation GO:0050870 101 0.237
protein secretion GO:0009306 111 0.236
Mouse
positive regulation of immune effector process GO:0002699 107 0.235
regulation of t cell proliferation GO:0042129 92 0.229
mature dendritic cell differentiation GO:0097029 3 0.229
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.215
immune response regulating signaling pathway GO:0002764 125 0.213
Mouse
regulation of adaptive immune response GO:0002819 90 0.211
leukocyte migration GO:0050900 124 0.209
positive regulation of innate immune response GO:0045089 80 0.201
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.190
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.188
Mouse
regulation of response to wounding GO:1903034 189 0.182
Mouse
positive regulation of t cell proliferation GO:0042102 52 0.179
regulation of establishment of protein localization GO:0070201 181 0.176
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.176
regulation of b cell proliferation GO:0030888 39 0.175
regulation of cell migration GO:0030334 219 0.174
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.172
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.165
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.161
regulation of protein transport GO:0051223 163 0.161
Mouse
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.160
positive regulation of monocyte chemotaxis GO:0090026 2 0.160
alpha beta t cell activation GO:0046631 91 0.156
sequestering of metal ion GO:0051238 19 0.154
regulation of natural killer cell activation GO:0032814 22 0.152
dna recombination GO:0006310 92 0.151
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.151
activation of immune response GO:0002253 138 0.149
Mouse
regulation of transferase activity GO:0051338 263 0.147
positive regulation of cytokine production GO:0001819 174 0.146
Mouse
leukocyte apoptotic process GO:0071887 71 0.144
detection of molecule of bacterial origin GO:0032490 2 0.142
lymphocyte activation involved in immune response GO:0002285 93 0.141
regulation of monocyte chemotaxis GO:0090025 3 0.141
divalent inorganic cation transport GO:0072511 178 0.141
cellular response to lipid GO:0071396 145 0.138
positive regulation of t cell costimulation GO:2000525 2 0.132
defense response to bacterium GO:0042742 119 0.131
positive regulation of mapk cascade GO:0043410 170 0.129
regulation of immunoglobulin production GO:0002637 42 0.125
regulation of lymphocyte mediated immunity GO:0002706 84 0.125
chemotaxis GO:0006935 247 0.124
myeloid leukocyte activation GO:0002274 83 0.123
positive regulation of leukocyte proliferation GO:0070665 73 0.122
regulation of t cell differentiation GO:0045580 83 0.122
Mouse
negative regulation of molecular function GO:0044092 258 0.122
amine metabolic process GO:0009308 45 0.121
positive regulation of response to wounding GO:1903036 66 0.119
cellular ketone metabolic process GO:0042180 84 0.118
regulation of b cell activation GO:0050864 81 0.117
regulation of interleukin 10 secretion GO:2001179 4 0.117
regulation of lymphocyte activation GO:0051249 240 0.117
negative regulation of phosphate metabolic process GO:0045936 184 0.114
Mouse
regulation of production of molecular mediator of immune response GO:0002700 65 0.114
cellular amine metabolic process GO:0044106 44 0.113
negative regulation of macrophage apoptotic process GO:2000110 3 0.113
positive regulation of programmed cell death GO:0043068 218 0.108
positive regulation of cell death GO:0010942 224 0.108
positive regulation of leukocyte differentiation GO:1902107 86 0.107
Mouse
positive regulation of cell migration GO:0030335 109 0.106
negative regulation of cytokine production GO:0001818 84 0.105
Mouse
sequestering of calcium ion GO:0051208 18 0.104
defense response to gram positive bacterium GO:0050830 50 0.101
positive regulation of protein transport GO:0051222 93 0.101
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.101
b cell activation GO:0042113 161 0.101
Mouse
metal ion homeostasis GO:0055065 189 0.100
positive regulation of thymocyte migration GO:2000412 2 0.100
t helper 1 type immune response GO:0042088 25 0.100
cell chemotaxis GO:0060326 81 0.099
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.099
immunoglobulin production GO:0002377 73 0.099
ras protein signal transduction GO:0007265 77 0.097
regulation of cell motility GO:2000145 236 0.096
toll like receptor signaling pathway GO:0002224 38 0.096
Mouse
t cell activation involved in immune response GO:0002286 43 0.096
mapk cascade GO:0000165 281 0.096
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.094
Mouse
t cell mediated immunity GO:0002456 50 0.094
divalent inorganic cation homeostasis GO:0072507 138 0.094
innate immune response activating signal transduction GO:0002758 50 0.093
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.093
peptidyl amino acid modification GO:0018193 336 0.093
regulation of lymphocyte differentiation GO:0045619 107 0.092
Mouse
response to organic cyclic compound GO:0014070 198 0.091
regulation of leukocyte apoptotic process GO:2000106 56 0.091
positive regulation of leukocyte mediated immunity GO:0002705 70 0.090
membrane organization GO:0061024 245 0.089
calcium ion homeostasis GO:0055074 127 0.088
positive regulation of secretion by cell GO:1903532 114 0.087
Mouse
interleukin 10 secretion GO:0072608 4 0.087
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.086
organ or tissue specific immune response GO:0002251 13 0.086
tumor necrosis factor production GO:0032640 50 0.085
regulation of vesicle mediated transport GO:0060627 139 0.085
innate immune response GO:0045087 157 0.084
Mouse
regulation of t cell costimulation GO:2000523 2 0.084
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.084
cellular divalent inorganic cation homeostasis GO:0072503 127 0.083
positive regulation of b cell activation GO:0050871 49 0.082
cellular calcium ion homeostasis GO:0006874 119 0.082
regulation of immunological synapse formation GO:2000520 2 0.082
lymphocyte mediated immunity GO:0002449 139 0.082
interleukin 2 production GO:0032623 33 0.082
Mouse
negative regulation of phosphorylation GO:0042326 166 0.081
Mouse
regulation of interferon gamma production GO:0032649 57 0.081
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.079
Mouse
regulation of cytokine production involved in immune response GO:0002718 26 0.078
neutrophil migration GO:1990266 37 0.078
apoptotic signaling pathway GO:0097190 306 0.077
cellular metal ion homeostasis GO:0006875 151 0.076
regulation of alpha beta t cell proliferation GO:0046640 18 0.076
purine containing compound metabolic process GO:0072521 311 0.076
natural killer cell activation GO:0030101 44 0.075
regulation of interleukin 2 production GO:0032663 28 0.075
Mouse
activation of innate immune response GO:0002218 56 0.073
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.073
regulation of interleukin 1 production GO:0032652 26 0.072
positive regulation of protein secretion GO:0050714 52 0.071
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.071
regulation of membrane potential GO:0042391 192 0.070
negative regulation of growth GO:0045926 99 0.070
homeostasis of number of cells GO:0048872 210 0.069
myeloid cell differentiation GO:0030099 233 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.069
leukocyte chemotaxis GO:0030595 69 0.069
t cell receptor signaling pathway GO:0050852 46 0.069
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.068
antigen receptor mediated signaling pathway GO:0050851 64 0.068
Mouse
regulation of mapk cascade GO:0043408 248 0.067
Mouse
endocytosis GO:0006897 168 0.066
cellular chemical homeostasis GO:0055082 215 0.066
interleukin 1 production GO:0032612 31 0.066
regulation of kinase activity GO:0043549 249 0.064
extrinsic apoptotic signaling pathway GO:0097191 126 0.064
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.064
peptidyl tyrosine modification GO:0018212 145 0.064
thymocyte migration GO:0072679 2 0.064
negative regulation of protein secretion GO:0050709 20 0.064
Mouse
gland development GO:0048732 330 0.064
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.064
cellular homeostasis GO:0019725 240 0.063
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.063
myeloid cell apoptotic process GO:0033028 22 0.063
myeloid leukocyte migration GO:0097529 57 0.062
glycoprotein biosynthetic process GO:0009101 89 0.062
cell type specific apoptotic process GO:0097285 268 0.062
negative regulation of t cell activation GO:0050868 65 0.061
myeloid leukocyte differentiation GO:0002573 119 0.061
t helper cell differentiation GO:0042093 28 0.061
negative regulation of phosphorus metabolic process GO:0010563 184 0.061
Mouse
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.061
regulation of b cell mediated immunity GO:0002712 37 0.061
alpha beta t cell proliferation GO:0046633 21 0.060
cation homeostasis GO:0055080 212 0.060
positive regulation of cytokine production involved in immune response GO:0002720 19 0.060
positive regulation of eosinophil migration GO:2000418 2 0.059
t cell differentiation involved in immune response GO:0002292 30 0.058
nucleotide catabolic process GO:0009166 217 0.058
regulation of cellular component biogenesis GO:0044087 181 0.058
defense response to virus GO:0051607 68 0.058
Mouse
regulation of cellular catabolic process GO:0031329 242 0.058
eosinophil activation GO:0043307 1 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.057
immunoglobulin mediated immune response GO:0016064 69 0.057
cytokine metabolic process GO:0042107 71 0.057
Mouse
nucleotide metabolic process GO:0009117 332 0.057
isotype switching GO:0045190 36 0.057
regulation of cellular ketone metabolic process GO:0010565 66 0.057
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.056
positive regulation of cytokine secretion GO:0050715 41 0.056
Mouse
positive regulation of protein modification process GO:0031401 299 0.056
lymphocyte costimulation GO:0031294 15 0.055
b cell proliferation GO:0042100 53 0.055
cellular ion homeostasis GO:0006873 165 0.055
type 2 immune response GO:0042092 23 0.055
regulation of protein kinase activity GO:0045859 232 0.054
negative regulation of secretion GO:0051048 61 0.054
Mouse
heterocycle catabolic process GO:0046700 280 0.054
interferon gamma production GO:0032609 67 0.053
Mouse
t helper 1 cell cytokine production GO:0035744 1 0.053
regulation of tumor necrosis factor production GO:0032680 49 0.053
anion transport GO:0006820 177 0.052
nuclear transport GO:0051169 139 0.052
regulation of protein serine threonine kinase activity GO:0071900 157 0.052
granulocyte migration GO:0097530 43 0.052
positive regulation of inflammatory response GO:0050729 47 0.051
regulation of multi organism process GO:0043900 111 0.051
macromolecule catabolic process GO:0009057 281 0.051
regulation of t cell extravasation GO:2000407 3 0.051
cytoplasmic transport GO:0016482 234 0.051
organic hydroxy compound metabolic process GO:1901615 203 0.051
cdc42 protein signal transduction GO:0032488 0 0.051
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.051
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.051
nucleoside phosphate metabolic process GO:0006753 338 0.050
neutrophil chemotaxis GO:0030593 36 0.050
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.050
glycoprotein metabolic process GO:0009100 116 0.050
carbohydrate derivative biosynthetic process GO:1901137 183 0.049
regulation of reactive oxygen species metabolic process GO:2000377 40 0.049
positive regulation of protein phosphorylation GO:0001934 242 0.049
regulation of thymocyte migration GO:2000410 2 0.048
monocyte extravasation GO:0035696 2 0.048
peptidyl tyrosine phosphorylation GO:0018108 143 0.048
eosinophil degranulation GO:0043308 1 0.048
regulation of ion homeostasis GO:2000021 64 0.047
regulation of eosinophil migration GO:2000416 2 0.047
aromatic compound catabolic process GO:0019439 286 0.047
angiogenesis GO:0001525 201 0.046
positive regulation of interferon gamma production GO:0032729 39 0.046
positive regulation of t cell differentiation GO:0045582 52 0.046
Mouse
immune complex clearance GO:0002434 2 0.046
positive regulation of immunological synapse formation GO:2000522 1 0.046
positive regulation of cellular catabolic process GO:0031331 148 0.045
alpha beta t cell activation involved in immune response GO:0002287 31 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.045
negative regulation of immune effector process GO:0002698 55 0.044
regulation of body fluid levels GO:0050878 162 0.044
regulation of system process GO:0044057 200 0.044
somatic cell dna recombination GO:0016444 51 0.044
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.044
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.044
cytokine mediated signaling pathway GO:0019221 115 0.043
eosinophil migration GO:0072677 3 0.043
regulation of t helper 1 type immune response GO:0002825 17 0.043
negative regulation of serotonin secretion GO:0014063 2 0.043
positive regulation of lymphocyte migration GO:2000403 11 0.043
regulation of organelle organization GO:0033043 289 0.042
rho protein signal transduction GO:0007266 32 0.042
positive regulation of apoptotic process GO:0043065 217 0.042
eosinophil activation involved in immune response GO:0002278 1 0.042
protein localization to nucleus GO:0034504 121 0.042
divalent metal ion transport GO:0070838 172 0.041
cation transport GO:0006812 399 0.041
exocytosis GO:0006887 121 0.041
blood vessel morphogenesis GO:0048514 285 0.041
positive regulation of adaptive immune response GO:0002821 61 0.041
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.041
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.041
regulation of acute inflammatory response GO:0002673 27 0.040
organonitrogen compound catabolic process GO:1901565 264 0.040
b cell activation involved in immune response GO:0002312 50 0.040
negative regulation of defense response GO:0031348 77 0.040
Mouse
protein localization to organelle GO:0033365 185 0.040
regulation of homeostatic process GO:0032844 182 0.040
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.040
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.040
cytokine biosynthetic process GO:0042089 68 0.040
Mouse
t helper 17 cell chemotaxis GO:0035705 1 0.040
negative regulation of lymphocyte activation GO:0051250 91 0.040
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.039
action potential GO:0001508 78 0.039
positive regulation of t cell extravasation GO:2000409 2 0.039
interleukin 12 production GO:0032615 32 0.039
cellular modified amino acid metabolic process GO:0006575 63 0.039
glycosyl compound catabolic process GO:1901658 206 0.039
transepithelial chloride transport GO:0030321 4 0.039
t cell costimulation GO:0031295 14 0.039
i kappab kinase nf kappab signaling GO:0007249 85 0.039
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.039
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.038
lymphocyte migration GO:0072676 26 0.038
positive regulation of alpha beta t cell activation GO:0046635 39 0.038
helper t cell chemotaxis GO:0035704 1 0.037
detection of stimulus GO:0051606 84 0.037
jnk cascade GO:0007254 72 0.037
dendritic cell antigen processing and presentation GO:0002468 7 0.037
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
negative regulation of eosinophil degranulation GO:0043310 1 0.037
stress activated mapk cascade GO:0051403 80 0.037
mast cell activation GO:0045576 27 0.037
negative regulation of interferon gamma production GO:0032689 18 0.036
Mouse
negative regulation of secretion by cell GO:1903531 54 0.036
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.036
Mouse
regulation of t helper 2 cell cytokine production GO:2000551 3 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
regulation of immunoglobulin mediated immune response GO:0002889 37 0.036
negative regulation of protein transport GO:0051224 46 0.036
Mouse
b cell mediated immunity GO:0019724 71 0.036
interleukin 18 production GO:0032621 4 0.035
inflammatory cell apoptotic process GO:0006925 11 0.035
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.035
positive regulation of immunoglobulin production GO:0002639 28 0.035
purine nucleotide catabolic process GO:0006195 211 0.035
negative regulation of multi organism process GO:0043901 68 0.035
multicellular organismal homeostasis GO:0048871 164 0.035
response to interferon gamma GO:0034341 34 0.034
purine nucleoside triphosphate metabolic process GO:0009144 226 0.034
regulation of interleukin 12 production GO:0032655 30 0.034
regulation of stress activated mapk cascade GO:0032872 69 0.034
positive regulation of hydrolase activity GO:0051345 148 0.033
regulation of eosinophil degranulation GO:0043309 1 0.033
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.033
ribonucleoside metabolic process GO:0009119 245 0.032
multicellular organismal signaling GO:0035637 91 0.032
muscle cell differentiation GO:0042692 261 0.032
activation of mapk activity GO:0000187 59 0.032
regulation of interleukin 10 production GO:0032653 21 0.032
negative regulation of cell activation GO:0050866 111 0.032
positive regulation of cell development GO:0010720 237 0.032
t cell extravasation GO:0072683 4 0.032
somatic diversification of immune receptors GO:0002200 53 0.032
growth of symbiont involved in interaction with host GO:0044116 23 0.032
regulation of jnk cascade GO:0046328 62 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
granulocyte chemotaxis GO:0071621 39 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.031
positive regulation of nervous system development GO:0051962 221 0.031
detection of fungus GO:0016046 2 0.031
regulation of apoptotic signaling pathway GO:2001233 197 0.031
cell recognition GO:0008037 83 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.031
morphogenesis of a branching structure GO:0001763 203 0.030
positive regulation of t cell migration GO:2000406 10 0.030
positive regulation of map kinase activity GO:0043406 84 0.030
regulation of dendritic cell chemotaxis GO:2000508 1 0.030
intracellular protein transport GO:0006886 204 0.030
acute inflammatory response GO:0002526 41 0.030
alpha beta t cell differentiation GO:0046632 69 0.030
natural killer cell chemotaxis GO:0035747 1 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
coagulation GO:0050817 78 0.030
positive regulation of cytokine biosynthetic process GO:0042108 40 0.030
Mouse
regulation of cellular response to stress GO:0080135 159 0.029
body fluid secretion GO:0007589 53 0.029
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.029
negative regulation of homeostatic process GO:0032845 71 0.029
regulation of cell adhesion GO:0030155 154 0.029
regulation of cell projection organization GO:0031344 206 0.029
erythrocyte differentiation GO:0030218 88 0.029
regulation of type 2 immune response GO:0002828 18 0.029
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.029
necroptotic process GO:0070266 21 0.029
germ cell development GO:0007281 185 0.029
positive regulation of kinase activity GO:0033674 155 0.029
regulation of exocytosis GO:0017157 61 0.028
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
positive regulation of transferase activity GO:0051347 167 0.028
necrotic cell death GO:0070265 30 0.028
positive regulation of monocyte extravasation GO:2000439 1 0.028
positive regulation of acute inflammatory response GO:0002675 16 0.028
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.028
dendritic cell differentiation GO:0097028 26 0.028
positive regulation of neutrophil migration GO:1902624 12 0.028
regulation of ion transport GO:0043269 215 0.028
cell cell recognition GO:0009988 44 0.028
microglial cell activation involved in immune response GO:0002282 1 0.028
neuron death GO:0070997 154 0.028
positive regulation of epithelial cell proliferation GO:0050679 68 0.027
protein catabolic process GO:0030163 221 0.027
regulation of alpha beta t cell differentiation GO:0046637 35 0.027
negative regulation of leukocyte differentiation GO:1902106 51 0.027
jak stat cascade GO:0007259 42 0.027
regulation of erk1 and erk2 cascade GO:0070372 71 0.027
Mouse
anatomical structure homeostasis GO:0060249 145 0.027
regulation of jun kinase activity GO:0043506 40 0.027
cell fate commitment GO:0045165 210 0.027
glial cell differentiation GO:0010001 131 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
Mouse
sensory perception GO:0007600 245 0.027
regulation of myeloid cell differentiation GO:0045637 96 0.026
regulation of hydrolase activity GO:0051336 246 0.026
interleukin 1 beta production GO:0032611 30 0.026
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.026
regulation of neutrophil migration GO:1902622 14 0.026
circulatory system process GO:0003013 197 0.026
positive regulation of chemotaxis GO:0050921 38 0.026
positive regulation of interleukin 12 production GO:0032735 21 0.026
epithelial cell proliferation GO:0050673 174 0.026
regulation of ras gtpase activity GO:0032318 88 0.026
regulation of lymphocyte apoptotic process GO:0070228 41 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of calcium mediated signaling GO:0050848 19 0.026
t cell selection GO:0045058 34 0.025
neuron apoptotic process GO:0051402 142 0.025
fat cell differentiation GO:0045444 160 0.025
regulation of cell cycle GO:0051726 281 0.025
Mouse
regulation of protein complex assembly GO:0043254 83 0.025
carboxylic acid transport GO:0046942 100 0.025
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.025
regulation of map kinase activity GO:0043405 120 0.025
reactive nitrogen species metabolic process GO:2001057 0 0.025
leukocyte degranulation GO:0043299 27 0.025
t cell differentiation in thymus GO:0033077 77 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
regulation of interleukin 6 production GO:0032675 55 0.025
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.025
positive regulation of cell motility GO:2000147 116 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.024
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.024
cytosolic calcium ion transport GO:0060401 48 0.024
fertilization GO:0009566 127 0.024
inflammatory response to antigenic stimulus GO:0002437 30 0.024
positive regulation of cell adhesion GO:0045785 80 0.024
blood circulation GO:0008015 195 0.024
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.024
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.024
protein import into nucleus GO:0006606 95 0.024
immune complex clearance by monocytes and macrophages GO:0002436 2 0.024
calcium ion transport into cytosol GO:0060402 48 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.023
telencephalon development GO:0021537 186 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
stress activated protein kinase signaling cascade GO:0031098 81 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
leukocyte mediated cytotoxicity GO:0001909 62 0.023
positive regulation of neutrophil chemotaxis GO:0090023 12 0.023
calcium ion transport GO:0006816 159 0.023
interspecies interaction between organisms GO:0044419 83 0.023
myotube differentiation GO:0014902 105 0.023
regulation of cell killing GO:0031341 40 0.023
cytosolic calcium ion homeostasis GO:0051480 70 0.023
positive regulation of behavior GO:0048520 40 0.023
nuclear import GO:0051170 95 0.023
mature natural killer cell chemotaxis GO:0035782 1 0.023
cell adhesion GO:0007155 329 0.023
positive regulation of tumor necrosis factor production GO:0032760 30 0.023
regulation of osteoclast differentiation GO:0045670 36 0.023
interferon beta biosynthetic process GO:0045350 4 0.023
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.022
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.022
positive regulation of t helper 1 type immune response GO:0002827 12 0.022
myeloid cell activation involved in immune response GO:0002275 34 0.022
negative regulation of leukocyte apoptotic process GO:2000107 31 0.022
regulation of rho protein signal transduction GO:0035023 71 0.022
positive regulation of jnk cascade GO:0046330 46 0.022
regulation of hormone levels GO:0010817 211 0.022
regulation of t helper 1 cell cytokine production GO:2000554 1 0.022
maintenance of location GO:0051235 89 0.022
negative regulation of mapk cascade GO:0043409 65 0.022
Mouse
organophosphate catabolic process GO:0046434 232 0.022
negative regulation of interleukin 10 secretion GO:2001180 2 0.022

Pdcd1lg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org