Mus musculus

0 known processes

Sec31a

Sec31 homolog A (S. cerevisiae)

(Aliases: HSPC275,1810024J13Rik,Sec31l1,AU042160,ABP125,ABP130)

Sec31a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.293
protein hydroxylation GO:0018126 4 0.221
peptidyl proline hydroxylation GO:0019511 3 0.220
copii coated vesicle budding GO:0090114 2 0.155
Yeast
endomembrane system organization GO:0010256 147 0.151
Zebrafish
negative regulation of synapse assembly GO:0051964 3 0.129
membrane organization GO:0061024 245 0.121
Yeast
spermatogenesis GO:0007283 284 0.117
response to endoplasmic reticulum stress GO:0034976 53 0.108
cellular amine metabolic process GO:0044106 44 0.106
maintenance of location GO:0051235 89 0.097
regulation of lipid storage GO:0010883 20 0.097
male gamete generation GO:0048232 285 0.095
fatty acid transmembrane transport GO:1902001 1 0.091
nucleobase containing small molecule metabolic process GO:0055086 352 0.085
cation transport GO:0006812 399 0.083
cellular amino acid metabolic process GO:0006520 103 0.069
cytoplasmic transport GO:0016482 234 0.069
Yeast
metal ion homeostasis GO:0055065 189 0.067
ion transmembrane transport GO:0034220 361 0.065
negative regulation of cell size GO:0045792 3 0.063
kidney development GO:0001822 213 0.062
regulation of ossification GO:0030278 112 0.059
modification dependent protein catabolic process GO:0019941 133 0.059
endocytosis GO:0006897 168 0.058
lipid localization GO:0010876 126 0.058
positive regulation of cell death GO:0010942 224 0.057
lipid storage GO:0019915 36 0.056
rna splicing GO:0008380 54 0.056
ribonucleotide catabolic process GO:0009261 208 0.056
establishment of protein localization to organelle GO:0072594 118 0.056
ribose phosphate metabolic process GO:0019693 291 0.055
modification dependent macromolecule catabolic process GO:0043632 133 0.054
wnt signaling pathway GO:0016055 188 0.054
cation transmembrane transport GO:0098655 266 0.051
protein modification by small protein conjugation or removal GO:0070647 207 0.051
connective tissue development GO:0061448 179 0.051
cation homeostasis GO:0055080 212 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
mrna metabolic process GO:0016071 84 0.048
regulation of protein stability GO:0031647 52 0.047
dna metabolic process GO:0006259 303 0.046
embryonic skeletal system development GO:0048706 120 0.045
amine metabolic process GO:0009308 45 0.044
regulation of cell activation GO:0050865 289 0.044
nucleotide metabolic process GO:0009117 332 0.044
renal system development GO:0072001 225 0.044
glycosyl compound metabolic process GO:1901657 246 0.044
sulfur compound biosynthetic process GO:0044272 37 0.043
purine containing compound metabolic process GO:0072521 311 0.043
cargo loading into vesicle GO:0035459 3 0.041
leukocyte differentiation GO:0002521 342 0.040
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.039
sulfur compound metabolic process GO:0006790 100 0.039
ossification GO:0001503 216 0.039
retina morphogenesis in camera type eye GO:0060042 45 0.038
nucleoside catabolic process GO:0009164 206 0.038
regulation of t cell activation GO:0050863 170 0.038
inorganic cation transmembrane transport GO:0098662 207 0.036
inorganic ion transmembrane transport GO:0098660 234 0.036
monocarboxylic acid metabolic process GO:0032787 191 0.035
protein localization to membrane GO:0072657 108 0.035
regulation of body fluid levels GO:0050878 162 0.034
regulation of neuron differentiation GO:0045664 281 0.034
ubiquitin dependent protein catabolic process GO:0006511 129 0.034
pancreatic juice secretion GO:0030157 4 0.034
cellular ion homeostasis GO:0006873 165 0.034
purine containing compound catabolic process GO:0072523 213 0.033
bone development GO:0060348 120 0.033
skeletal system development GO:0001501 356 0.033
lateral inhibition GO:0046331 1 0.032
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.032
cellular macromolecule catabolic process GO:0044265 206 0.032
cellular alcohol metabolic process GO:0044107 3 0.032
regulation of leukocyte differentiation GO:1902105 159 0.031
peptidyl amino acid modification GO:0018193 336 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
cellular homeostasis GO:0019725 240 0.031
ras protein signal transduction GO:0007265 77 0.030
er to golgi vesicle mediated transport GO:0006888 11 0.030
Yeast
rna processing GO:0006396 105 0.030
negative regulation of molecular function GO:0044092 258 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.029
cartilage development GO:0051216 140 0.029
dna alkylation GO:0006305 43 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
t cell activation GO:0042110 289 0.029
organic acid transport GO:0015849 101 0.028
chondrocyte differentiation GO:0002062 72 0.028
glycoprotein metabolic process GO:0009100 116 0.028
positive regulation of nucleotide catabolic process GO:0030813 88 0.028
divalent inorganic cation homeostasis GO:0072507 138 0.028
regulation of nucleotide metabolic process GO:0006140 169 0.027
cellular response to lipid GO:0071396 145 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
misfolded protein transport GO:0070843 1 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
posttranslational protein targeting to membrane GO:0006620 2 0.027
aromatic compound catabolic process GO:0019439 286 0.027
urogenital system development GO:0001655 261 0.027
adult behavior GO:0030534 135 0.027
regulation of myeloid leukocyte differentiation GO:0002761 58 0.026
transmembrane transport GO:0055085 412 0.026
protein import GO:0017038 101 0.026
photoreceptor cell differentiation GO:0046530 52 0.025
intra golgi vesicle mediated transport GO:0006891 1 0.025
oxidation reduction process GO:0055114 342 0.025
adult locomotory behavior GO:0008344 91 0.025
action potential GO:0001508 78 0.025
circadian rhythm GO:0007623 114 0.025
lymphocyte differentiation GO:0030098 242 0.024
regulation of hydrolase activity GO:0051336 246 0.024
phagocytosis GO:0006909 66 0.024
peptidyl proline modification GO:0018208 6 0.024
regulation of lymphocyte activation GO:0051249 240 0.024
regulation of lymphocyte differentiation GO:0045619 107 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.024
t cell differentiation GO:0030217 174 0.024
multicellular organism growth GO:0035264 161 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
skeletal system morphogenesis GO:0048705 203 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
phosphatidic acid biosynthetic process GO:0006654 2 0.023
gland development GO:0048732 330 0.023
Zebrafish
alpha beta t cell activation GO:0046631 91 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
mrna splicing via spliceosome GO:0000398 43 0.023
protein localization to nucleus GO:0034504 121 0.023
epithalamus development GO:0021538 2 0.023
regulation of cellular protein catabolic process GO:1903362 61 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
forebrain development GO:0030900 302 0.022
protein ubiquitination GO:0016567 171 0.022
protein catabolic process GO:0030163 221 0.022
anion transport GO:0006820 177 0.022
regulation of cell motility GO:2000145 236 0.022
embryonic organ morphogenesis GO:0048562 276 0.021
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.021
cellular chemical homeostasis GO:0055082 215 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
synaptic transmission GO:0007268 329 0.021
intracellular protein transport GO:0006886 204 0.021
organelle fission GO:0048285 170 0.021
alpha beta t cell differentiation GO:0046632 69 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
golgi vesicle transport GO:0048193 30 0.021
Yeast
nucleoside triphosphate catabolic process GO:0009143 205 0.021
phosphatidic acid metabolic process GO:0046473 2 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.020
skin development GO:0043588 220 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
negative regulation of fatty acid oxidation GO:0046322 5 0.020
positive regulation of organelle organization GO:0010638 128 0.020
locomotory behavior GO:0007626 195 0.020
response to uv GO:0009411 44 0.020
cellular response to peptide hormone stimulus GO:0071375 92 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
lymphocyte homeostasis GO:0002260 64 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
regulation of anatomical structure size GO:0090066 178 0.020
response to organonitrogen compound GO:0010243 246 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
protein localization to organelle GO:0033365 185 0.020
regulation of fatty acid beta oxidation GO:0031998 1 0.019
positive regulation of cellular component biogenesis GO:0044089 94 0.019
diencephalon development GO:0021536 63 0.019
rna splicing via transesterification reactions GO:0000375 43 0.019
single organism nuclear import GO:1902593 95 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
response to acid chemical GO:0001101 111 0.019
positive regulation of gtpase activity GO:0043547 85 0.018
gliogenesis GO:0042063 141 0.018
negative regulation of nervous system development GO:0051961 156 0.018
regulation of organelle organization GO:0033043 289 0.018
neural tube development GO:0021915 160 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
positive regulation of apoptotic cell clearance GO:2000427 3 0.018
regulation of chromatin modification GO:1903308 57 0.018
regulation of organ morphogenesis GO:2000027 144 0.018
glycosyl compound catabolic process GO:1901658 206 0.017
habenula development GO:0021986 2 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
sensory organ morphogenesis GO:0090596 242 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
protein import into nucleus GO:0006606 95 0.017
bone morphogenesis GO:0060349 78 0.017
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
cellular protein complex assembly GO:0043623 116 0.017
tube formation GO:0035148 140 0.017
positive regulation of interleukin 10 secretion GO:2001181 1 0.017
neural retina development GO:0003407 41 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
immune effector process GO:0002252 321 0.017
fat cell differentiation GO:0045444 160 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
regulation of protein complex assembly GO:0043254 83 0.016
cell growth GO:0016049 130 0.016
anion transmembrane transport GO:0098656 71 0.016
macromolecule catabolic process GO:0009057 281 0.016
organic anion transport GO:0015711 137 0.016
dendrite development GO:0016358 115 0.016
extracellular structure organization GO:0043062 148 0.016
cellular response to zinc ion starvation GO:0034224 2 0.016
negative regulation of growth GO:0045926 99 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
transmission of nerve impulse GO:0019226 76 0.015
positive regulation of interleukin 5 secretion GO:2000664 1 0.015
cell fate commitment GO:0045165 210 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
tube closure GO:0060606 91 0.015
vascular process in circulatory system GO:0003018 62 0.015
retrograde transport endosome to golgi GO:0042147 2 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
regulation of ral protein signal transduction GO:0032485 4 0.015
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.015
response to radiation GO:0009314 165 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
response to organic cyclic compound GO:0014070 198 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
localization within membrane GO:0051668 4 0.015
Yeast
purine nucleotide catabolic process GO:0006195 211 0.015
negative regulation of protein modification process GO:0031400 163 0.015
intracellular distribution of mitochondria GO:0048312 1 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
covalent chromatin modification GO:0016569 163 0.014
positive regulation of interleukin 13 secretion GO:2000667 1 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
regulation of alpha beta t cell activation GO:0046634 53 0.014
positive regulation of wnt signaling pathway GO:0030177 45 0.014
circadian regulation of gene expression GO:0032922 48 0.014
regulation of tor signaling GO:0032006 17 0.014
regulation of t cell differentiation GO:0045580 83 0.014
acetate ester transport GO:1901374 2 0.014
positive regulation of cell development GO:0010720 237 0.014
rhythmic process GO:0048511 174 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
chromatin organization GO:0006325 206 0.014
telencephalon development GO:0021537 186 0.014
divalent inorganic cation transport GO:0072511 178 0.014
regulation of metal ion transport GO:0010959 106 0.014
macromolecular complex disassembly GO:0032984 43 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
spermatid differentiation GO:0048515 115 0.014
regulation of homeostatic process GO:0032844 182 0.014
cellular protein catabolic process GO:0044257 155 0.014
protein maturation GO:0051604 176 0.014
ensheathment of neurons GO:0007272 76 0.014
regulation of cell projection organization GO:0031344 206 0.014
glucose homeostasis GO:0042593 128 0.014
actin cytoskeleton organization GO:0030036 220 0.014
vesicle localization GO:0051648 86 0.014
insulin receptor signaling pathway GO:0008286 49 0.014
plasma membrane organization GO:0007009 90 0.014
single fertilization GO:0007338 82 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.013
protein targeting GO:0006605 143 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
protein transport into membrane raft GO:0032596 4 0.013
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:1900740 3 0.013
defecation GO:0030421 1 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
biomineral tissue development GO:0031214 64 0.013
camera type eye photoreceptor cell differentiation GO:0060219 15 0.013
organic acid catabolic process GO:0016054 51 0.013
circulatory system process GO:0003013 197 0.013
epithelial tube formation GO:0072175 130 0.013
meiotic cell cycle process GO:1903046 77 0.013
cell type specific apoptotic process GO:0097285 268 0.013
nucleotide sugar metabolic process GO:0009225 4 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
regulation of actin filament based process GO:0032970 99 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
chromatin modification GO:0016568 187 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of transmembrane transport GO:0034762 128 0.013
sequestering of calcium ion GO:0051208 18 0.013
cell recognition GO:0008037 83 0.013
positive regulation of t helper 2 cell activation GO:2000570 2 0.013
stem cell differentiation GO:0048863 268 0.013
positive regulation of ion transport GO:0043270 65 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
establishment of protein localization to membrane GO:0090150 54 0.012
blood circulation GO:0008015 195 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
response to interleukin 15 GO:0070672 3 0.012
response to inorganic substance GO:0010035 96 0.012
Human
methylation GO:0032259 134 0.012
positive regulation of phospholipase activity GO:0010518 3 0.012
cellular protein complex disassembly GO:0043624 36 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
protein stabilization GO:0050821 25 0.012
sensory perception GO:0007600 245 0.012
epithelial cell development GO:0002064 159 0.012
stem cell development GO:0048864 219 0.012
glycogen cell differentiation involved in embryonic placenta development GO:0060709 1 0.012
macromolecule methylation GO:0043414 120 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
glial cell differentiation GO:0010001 131 0.012
nucleotide catabolic process GO:0009166 217 0.012
respiratory tube development GO:0030323 167 0.012
germ cell development GO:0007281 185 0.012
small molecule catabolic process GO:0044282 71 0.012
regulation of tube size GO:0035150 57 0.012
insulin like growth factor receptor signaling pathway GO:0048009 21 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
regulation of biomineral tissue development GO:0070167 33 0.012
fatty acid metabolic process GO:0006631 121 0.012
lung development GO:0030324 164 0.012
myeloid cell homeostasis GO:0002262 114 0.012
positive regulation of protein modification process GO:0031401 299 0.012
negative regulation of organelle organization GO:0010639 90 0.012
cellular response to hypoxia GO:0071456 17 0.012
regulation of cell adhesion GO:0030155 154 0.012
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.011
activation of phospholipase c activity GO:0007202 2 0.011
regulation of circadian rhythm GO:0042752 58 0.011
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
axis elongation involved in somitogenesis GO:0090245 4 0.011
regulation of cell migration GO:0030334 219 0.011
retina development in camera type eye GO:0060041 119 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
positive regulation of cholesterol biosynthetic process GO:0045542 3 0.011
vesicle organization GO:0016050 60 0.011
Yeast
receptor biosynthetic process GO:0032800 3 0.011
schwann cell differentiation GO:0014037 26 0.011
regulation of transferase activity GO:0051338 263 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
regulation of mrna metabolic process GO:1903311 43 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
cellular ketone metabolic process GO:0042180 84 0.011
eye photoreceptor cell differentiation GO:0001754 41 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
embryonic skeletal system morphogenesis GO:0048704 91 0.011
regulation of stress fiber assembly GO:0051492 15 0.011
atp metabolic process GO:0046034 75 0.011
schwann cell development GO:0014044 22 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
response to retinoic acid GO:0032526 56 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
actin filament bundle assembly GO:0051017 40 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of heart contraction GO:0008016 77 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
sodium ion transport GO:0006814 73 0.011
regulation of system process GO:0044057 200 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
positive regulation of cell activation GO:0050867 158 0.011
regulation of cellular component size GO:0032535 121 0.010
activation of adenylate cyclase activity GO:0007190 4 0.010
response to light stimulus GO:0009416 135 0.010
synapse organization GO:0050808 125 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
mrna processing GO:0006397 63 0.010
attachment of spindle microtubules to kinetochore GO:0008608 4 0.010
heterocycle catabolic process GO:0046700 280 0.010
lipid transport GO:0006869 98 0.010
compound eye development GO:0048749 1 0.010
forebrain generation of neurons GO:0021872 63 0.010
regionalization GO:0003002 337 0.010
rho protein signal transduction GO:0007266 32 0.010

Sec31a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.126
bone development disease DOID:0080006 0 0.126
bone disease DOID:0080001 0 0.126
disease of anatomical entity DOID:7 0 0.126
musculoskeletal system disease DOID:17 0 0.126
connective tissue disease DOID:65 0 0.126
retinal disease DOID:5679 0 0.085
retinal degeneration DOID:8466 0 0.085
sensory system disease DOID:0050155 0 0.085
eye and adnexa disease DOID:1492 0 0.085
nervous system disease DOID:863 0 0.085
eye disease DOID:5614 0 0.085
central nervous system disease DOID:331 0 0.038
osteogenesis imperfecta DOID:12347 0 0.033
retinitis pigmentosa DOID:10584 0 0.020
thoracic cancer DOID:5093 0 0.020
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
cardiovascular system disease DOID:1287 0 0.014
motor neuron disease DOID:231 0 0.014
amyotrophic lateral sclerosis DOID:332 0 0.014
neurodegenerative disease DOID:1289 0 0.014
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013
muscle tissue disease DOID:66 0 0.013
neuromuscular disease DOID:440 0 0.011
charcot marie tooth disease type 2 DOID:0050539 0 0.011
charcot marie tooth disease DOID:10595 0 0.011
neuropathy DOID:870 0 0.011
breast cancer DOID:1612 0 0.011