Mus musculus

0 known processes

Psmd8

proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

(Aliases: AL033291,6720456J22Rik,AL033322,AL033323,C76433,AA407360)

Psmd8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.493
modification dependent macromolecule catabolic process GO:0043632 133 0.431
cellular protein catabolic process GO:0044257 155 0.358
ubiquitin dependent protein catabolic process GO:0006511 129 0.291
cellular response to dna damage stimulus GO:0006974 207 0.222
modification dependent protein catabolic process GO:0019941 133 0.216
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.210
proteasomal protein catabolic process GO:0010498 98 0.203
protein catabolic process GO:0030163 221 0.169
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.167
regulation of cell cycle process GO:0010564 160 0.111
cellular macromolecule catabolic process GO:0044265 206 0.098
protein modification by small protein conjugation GO:0032446 187 0.096
regulation of cell cycle GO:0051726 281 0.091
regulation of nucleotide metabolic process GO:0006140 169 0.091
positive regulation of nucleoside metabolic process GO:0045979 91 0.085
protein modification by small protein conjugation or removal GO:0070647 207 0.084
nucleoside triphosphate metabolic process GO:0009141 230 0.084
nucleoside metabolic process GO:0009116 246 0.078
regulation of nucleoside metabolic process GO:0009118 130 0.077
positive regulation of gtpase activity GO:0043547 85 0.075
macromolecule catabolic process GO:0009057 281 0.073
negative regulation of organelle organization GO:0010639 90 0.072
vesicle organization GO:0016050 60 0.069
metal ion homeostasis GO:0055065 189 0.068
mitotic cell cycle GO:0000278 195 0.068
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.066
negative regulation of cellular component organization GO:0051129 194 0.065
microtubule based process GO:0007017 236 0.062
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.060
cellular chemical homeostasis GO:0055082 215 0.059
rna interference GO:0016246 2 0.057
regulation of gtp catabolic process GO:0033124 113 0.055
small gtpase mediated signal transduction GO:0007264 97 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.053
purine ribonucleoside metabolic process GO:0046128 241 0.052
positive regulation of cellular catabolic process GO:0031331 148 0.051
cellular homeostasis GO:0019725 240 0.051
positive regulation of nucleotide catabolic process GO:0030813 88 0.051
male gamete generation GO:0048232 285 0.050
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.050
gene silencing by rna GO:0031047 19 0.049
t cell activation GO:0042110 289 0.049
regulation of cell division GO:0051302 76 0.048
positive regulation of hydrolase activity GO:0051345 148 0.048
cell division GO:0051301 120 0.048
mitotic cell cycle process GO:1903047 159 0.047
cellular response to glucose stimulus GO:0071333 45 0.047
intracellular protein transport GO:0006886 204 0.046
ribonucleoside metabolic process GO:0009119 245 0.046
spermatogenesis GO:0007283 284 0.045
positive regulation of gtp catabolic process GO:0033126 85 0.045
protein ubiquitination GO:0016567 171 0.045
epithelial tube morphogenesis GO:0060562 303 0.044
cellular ion homeostasis GO:0006873 165 0.044
posttranscriptional gene silencing GO:0016441 10 0.043
regulation of cytoskeleton organization GO:0051493 122 0.042
photoreceptor cell development GO:0042461 40 0.040
regulation of organelle organization GO:0033043 289 0.039
regulation of anatomical structure size GO:0090066 178 0.039
cellular protein complex assembly GO:0043623 116 0.039
positive regulation of nucleotide metabolic process GO:0045981 114 0.039
extracellular matrix organization GO:0030198 147 0.038
cation homeostasis GO:0055080 212 0.037
purine ribonucleotide metabolic process GO:0009150 290 0.036
posttranscriptional gene silencing by rna GO:0035194 10 0.036
regulation of cellular component size GO:0032535 121 0.035
synaptic transmission GO:0007268 329 0.035
trna wobble uridine modification GO:0002098 2 0.035
mitotic cytokinesis GO:0000281 4 0.034
meiotic nuclear division GO:0007126 115 0.034
ras protein signal transduction GO:0007265 77 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.032
endocytosis GO:0006897 168 0.032
negative regulation of intracellular signal transduction GO:1902532 167 0.032
cation transport GO:0006812 399 0.031
camera type eye development GO:0043010 266 0.031
extracellular structure organization GO:0043062 148 0.031
dephosphorylation GO:0016311 129 0.031
guanosine containing compound metabolic process GO:1901068 144 0.030
cellular amino acid metabolic process GO:0006520 103 0.030
localization within membrane GO:0051668 4 0.030
exocytosis GO:0006887 121 0.029
microtubule cytoskeleton organization GO:0000226 157 0.029
histone modification GO:0016570 159 0.029
protein import GO:0017038 101 0.028
stem cell differentiation GO:0048863 268 0.028
gene silencing GO:0016458 38 0.027
iron sulfur cluster assembly GO:0016226 3 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
purine nucleotide metabolic process GO:0006163 302 0.026
rhythmic process GO:0048511 174 0.026
transition metal ion homeostasis GO:0055076 54 0.025
cytoplasmic transport GO:0016482 234 0.025
ameboidal type cell migration GO:0001667 128 0.025
nuclear import GO:0051170 95 0.025
metallo sulfur cluster assembly GO:0031163 3 0.024
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
chromatin organization GO:0006325 206 0.024
membrane organization GO:0061024 245 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.023
gliogenesis GO:0042063 141 0.023
regulation of actin cytoskeleton organization GO:0032956 84 0.023
meiotic cell cycle process GO:1903046 77 0.023
organophosphate catabolic process GO:0046434 232 0.023
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.023
regulation of cellular component biogenesis GO:0044087 181 0.022
single organism nuclear import GO:1902593 95 0.022
heterocycle catabolic process GO:0046700 280 0.022
organism emergence from protective structure GO:0071684 4 0.021
body morphogenesis GO:0010171 45 0.021
spindle organization GO:0007051 28 0.021
centrosome organization GO:0051297 26 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
regulation of hydrolase activity GO:0051336 246 0.021
cellular amine metabolic process GO:0044106 44 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
protein polymerization GO:0051258 57 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
chromosome segregation GO:0007059 48 0.021
glycerolipid metabolic process GO:0046486 122 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
apoptotic signaling pathway GO:0097190 306 0.020
positive regulation of protein modification process GO:0031401 299 0.020
actin cytoskeleton organization GO:0030036 220 0.020
nitrogen compound transport GO:0071705 271 0.019
positive regulation of cell cycle GO:0045787 92 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
sensory organ morphogenesis GO:0090596 242 0.019
striated muscle myosin thick filament assembly GO:0071688 1 0.019
receptor mediated endocytosis GO:0006898 51 0.018
trna wobble base modification GO:0002097 2 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
positive regulation of mitotic cell cycle GO:0045931 41 0.018
organelle localization GO:0051640 179 0.018
negative regulation of cell motility GO:2000146 61 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
positive regulation of proteolysis GO:0045862 85 0.018
cellular transition metal ion homeostasis GO:0046916 32 0.018
protein neddylation GO:0045116 1 0.018
positive regulation of cell cycle process GO:0090068 61 0.018
cellular ketone metabolic process GO:0042180 84 0.017
regulation of cellular amine metabolic process GO:0033238 20 0.017
protein import into nucleus GO:0006606 95 0.017
muscle cell development GO:0055001 133 0.017
protein targeting GO:0006605 143 0.017
phospholipid metabolic process GO:0006644 87 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
lymphocyte differentiation GO:0030098 242 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
endomembrane system organization GO:0010256 147 0.017
actin filament organization GO:0007015 113 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
meiotic cell cycle GO:0051321 122 0.017
immune effector process GO:0002252 321 0.016
response to organonitrogen compound GO:0010243 246 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
multi multicellular organism process GO:0044706 109 0.016
myeloid cell differentiation GO:0030099 233 0.016
maintenance of location GO:0051235 89 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
gtp metabolic process GO:0046039 144 0.016
purine ribonucleotide biosynthetic process GO:0009152 59 0.016
cytokinetic process GO:0032506 2 0.016
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
response to organic cyclic compound GO:0014070 198 0.015
carbohydrate homeostasis GO:0033500 128 0.015
dna recombination GO:0006310 92 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
regulation of protein complex assembly GO:0043254 83 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
positive regulation of organelle organization GO:0010638 128 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
regulation of microtubule cytoskeleton organization GO:0070507 37 0.015
negative regulation of cell cycle process GO:0010948 69 0.014
regulation of microtubule based process GO:0032886 52 0.014
regulation of cell activation GO:0050865 289 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
regulation of protein targeting GO:1903533 61 0.014
regulation of protein ubiquitination GO:0031396 52 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of protein catabolic process GO:0042176 108 0.014
multicellular organismal aging GO:0010259 24 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
hydrogen transport GO:0006818 35 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
positive regulation of cell adhesion GO:0045785 80 0.014
proteasome assembly GO:0043248 1 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
purine containing compound metabolic process GO:0072521 311 0.014
retina morphogenesis in camera type eye GO:0060042 45 0.014
hepaticobiliary system development GO:0061008 67 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
protein maturation GO:0051604 176 0.014
ion transmembrane transport GO:0034220 361 0.014
regulation of cellular ketone metabolic process GO:0010565 66 0.014
positive regulation of protein complex assembly GO:0031334 45 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
regulation of actin filament based process GO:0032970 99 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
cell adhesion GO:0007155 329 0.013
cartilage development GO:0051216 140 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
stem cell development GO:0048864 219 0.013
cellular response to hexose stimulus GO:0071331 47 0.013
viral budding GO:0046755 1 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
response to growth factor GO:0070848 198 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
nucleus organization GO:0006997 45 0.013
nucleotide metabolic process GO:0009117 332 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
nucleoside catabolic process GO:0009164 206 0.012
divalent inorganic cation transport GO:0072511 178 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
organelle fission GO:0048285 170 0.012
dna metabolic process GO:0006259 303 0.012
mapk cascade GO:0000165 281 0.012
respiratory tube development GO:0030323 167 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
calcium ion transport GO:0006816 159 0.012
aromatic compound catabolic process GO:0019439 286 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
virion assembly GO:0019068 1 0.012
copii coated vesicle budding GO:0090114 2 0.012
actin filament polymerization GO:0030041 44 0.012
sulfur compound metabolic process GO:0006790 100 0.012
negative regulation of cell cycle GO:0045786 123 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
regulation of cell motility GO:2000145 236 0.012
blood vessel morphogenesis GO:0048514 285 0.012
retina development in camera type eye GO:0060041 119 0.012
regulation of proteolysis GO:0030162 164 0.012
muscle cell differentiation GO:0042692 261 0.012
actin polymerization or depolymerization GO:0008154 54 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.011
respiratory system development GO:0060541 190 0.011
regulation of protein maturation GO:1903317 96 0.011
negative regulation of protein processing GO:0010955 79 0.011
regulation of transferase activity GO:0051338 263 0.011
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
organelle fusion GO:0048284 28 0.011
locomotory behavior GO:0007626 195 0.011
regulation of homeostatic process GO:0032844 182 0.011
ovarian follicle development GO:0001541 40 0.011
ribose phosphate biosynthetic process GO:0046390 59 0.011
regulation of glycogen catabolic process GO:0005981 2 0.011
protein localization to organelle GO:0033365 185 0.011
oocyte construction GO:0007308 2 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
leukocyte differentiation GO:0002521 342 0.011
regulation of cell adhesion GO:0030155 154 0.011
chromatin modification GO:0016568 187 0.011
negative regulation of cellular protein catabolic process GO:1903363 22 0.011
cellular response to lipid GO:0071396 145 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
neural precursor cell proliferation GO:0061351 121 0.011
purine nucleoside catabolic process GO:0006152 205 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
circadian rhythm GO:0007623 114 0.010
protein localization to nucleus GO:0034504 121 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
eye photoreceptor cell differentiation GO:0001754 41 0.010
alpha beta t cell activation GO:0046631 91 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
rho protein signal transduction GO:0007266 32 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
phosphatidylglycerol metabolic process GO:0046471 3 0.010
amine metabolic process GO:0009308 45 0.010

Psmd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016