Mus musculus

0 known processes

Psmd3

proteasome (prosome, macropain) 26S subunit, non-ATPase, 3

(Aliases: AI255837,Psd3,Tstap91a,AntP91a,D11Bwg1349e)

Psmd3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 133 0.908
modification dependent macromolecule catabolic process GO:0043632 133 0.572
ubiquitin dependent protein catabolic process GO:0006511 129 0.536
protein modification by small protein conjugation GO:0032446 187 0.460
proteasomal protein catabolic process GO:0010498 98 0.424
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.370
t cell differentiation GO:0030217 174 0.350
macromolecule catabolic process GO:0009057 281 0.321
cellular protein catabolic process GO:0044257 155 0.297
protein catabolic process GO:0030163 221 0.270
protein modification by small protein conjugation or removal GO:0070647 207 0.244
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.211
cellular response to topologically incorrect protein GO:0035967 25 0.207
protein ubiquitination GO:0016567 171 0.196
cellular macromolecule catabolic process GO:0044265 206 0.190
rna interference GO:0016246 2 0.182
spermatogenesis GO:0007283 284 0.171
development of primary sexual characteristics GO:0045137 143 0.156
purine ribonucleoside metabolic process GO:0046128 241 0.116
ovarian follicle development GO:0001541 40 0.114
male gamete generation GO:0048232 285 0.108
gonad development GO:0008406 141 0.106
response to nutrient levels GO:0031667 109 0.104
response to organonitrogen compound GO:0010243 246 0.095
oogenesis GO:0048477 56 0.091
regulation of glucose metabolic process GO:0010906 60 0.090
ribonucleotide metabolic process GO:0009259 291 0.089
skin development GO:0043588 220 0.088
nucleotide metabolic process GO:0009117 332 0.087
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.085
inclusion body assembly GO:0070841 3 0.085
cytoplasmic transport GO:0016482 234 0.083
response to topologically incorrect protein GO:0035966 25 0.083
intracellular protein transport GO:0006886 204 0.083
posttranscriptional regulation of gene expression GO:0010608 155 0.082
retrograde transport endosome to golgi GO:0042147 2 0.079
purine nucleoside triphosphate metabolic process GO:0009144 226 0.075
purine ribonucleoside catabolic process GO:0046130 205 0.074
regulation of peptidase activity GO:0052547 96 0.072
positive regulation of growth hormone receptor signaling pathway GO:0060399 3 0.072
t cell differentiation in thymus GO:0033077 77 0.071
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.069
cellular response to dna damage stimulus GO:0006974 207 0.069
ribonucleotide catabolic process GO:0009261 208 0.068
negative regulation of protein metabolic process GO:0051248 282 0.065
regulation of protein catabolic process GO:0042176 108 0.065
purine containing compound metabolic process GO:0072521 311 0.064
purine nucleoside catabolic process GO:0006152 205 0.064
organic cyclic compound catabolic process GO:1901361 295 0.063
negative regulation of molecular function GO:0044092 258 0.063
purine nucleoside monophosphate catabolic process GO:0009128 58 0.063
purine nucleoside metabolic process GO:0042278 241 0.062
ras protein signal transduction GO:0007265 77 0.062
response to endoplasmic reticulum stress GO:0034976 53 0.061
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.060
protein targeting GO:0006605 143 0.060
ribose phosphate metabolic process GO:0019693 291 0.059
lymphocyte differentiation GO:0030098 242 0.058
aromatic compound catabolic process GO:0019439 286 0.058
small gtpase mediated signal transduction GO:0007264 97 0.057
spermatid differentiation GO:0048515 115 0.057
ribonucleoside triphosphate metabolic process GO:0009199 220 0.056
cellular nitrogen compound catabolic process GO:0044270 280 0.056
regulation of hydrolase activity GO:0051336 246 0.054
rhythmic process GO:0048511 174 0.053
leukocyte differentiation GO:0002521 342 0.052
ovulation cycle GO:0042698 59 0.052
regulation of cell cycle process GO:0010564 160 0.051
regulation of translational initiation GO:0006446 15 0.050
cellular carbohydrate metabolic process GO:0044262 119 0.050
mitotic cell cycle GO:0000278 195 0.050
purine nucleoside triphosphate catabolic process GO:0009146 203 0.050
oocyte construction GO:0007308 2 0.049
regulation of carbohydrate biosynthetic process GO:0043255 40 0.048
cellular response to nutrient levels GO:0031669 64 0.047
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.047
organophosphate catabolic process GO:0046434 232 0.047
compound eye development GO:0048749 1 0.047
aggresome assembly GO:0070842 2 0.046
positive regulation of endopeptidase activity GO:0010950 43 0.046
nucleotide catabolic process GO:0009166 217 0.046
regulation of proteolysis GO:0030162 164 0.046
cellular response to misfolded protein GO:0071218 5 0.046
rna catabolic process GO:0006401 29 0.045
ribonucleoside monophosphate catabolic process GO:0009158 57 0.045
hexose metabolic process GO:0019318 98 0.045
mesenchymal cell differentiation GO:0048762 107 0.044
er nucleus signaling pathway GO:0006984 27 0.044
oocyte axis specification GO:0007309 2 0.043
purine containing compound catabolic process GO:0072523 213 0.041
germ cell development GO:0007281 185 0.041
ribonucleoside triphosphate catabolic process GO:0009203 199 0.041
purine ribonucleotide catabolic process GO:0009154 208 0.040
female gamete generation GO:0007292 74 0.040
regulation of t cell activation GO:0050863 170 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
posttranscriptional gene silencing GO:0016441 10 0.039
attachment of spindle microtubules to kinetochore GO:0008608 4 0.039
nucleoside monophosphate metabolic process GO:0009123 85 0.038
positive regulation of proteolysis GO:0045862 85 0.038
negative regulation of camp mediated signaling GO:0043951 3 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.037
purine nucleotide metabolic process GO:0006163 302 0.036
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.036
positive regulation of peptidase activity GO:0010952 49 0.036
glycosyl compound catabolic process GO:1901658 206 0.035
glycosyl compound metabolic process GO:1901657 246 0.035
molting cycle GO:0042303 90 0.035
protein localization to organelle GO:0033365 185 0.035
response to misfolded protein GO:0051788 5 0.035
regulation of lymphocyte differentiation GO:0045619 107 0.034
multicellular organismal aging GO:0010259 24 0.034
regulation of proteasomal protein catabolic process GO:0061136 46 0.034
t cell activation GO:0042110 289 0.034
organonitrogen compound catabolic process GO:1901565 264 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
dephosphorylation GO:0016311 129 0.033
hexose biosynthetic process GO:0019319 39 0.033
epidermis development GO:0008544 187 0.033
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.033
positive regulation of hydrolase activity GO:0051345 148 0.032
gene silencing by rna GO:0031047 19 0.032
positive regulation of gtpase activity GO:0043547 85 0.032
regulation of t cell differentiation GO:0045580 83 0.032
cellular amine metabolic process GO:0044106 44 0.031
proteasome assembly GO:0043248 1 0.031
cellular response to extracellular stimulus GO:0031668 81 0.030
cellular protein complex assembly GO:0043623 116 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
heterocycle catabolic process GO:0046700 280 0.029
spermatid development GO:0007286 108 0.029
mitochondrion organization GO:0007005 134 0.029
positive regulation of cellular catabolic process GO:0031331 148 0.029
glucose metabolic process GO:0006006 92 0.028
regulation of rna splicing GO:0043484 37 0.028
regulation of cell activation GO:0050865 289 0.028
endoplasmic reticulum unfolded protein response GO:0030968 19 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
female gonad development GO:0008585 71 0.028
multicellular organism growth GO:0035264 161 0.028
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.027
cellular ketone metabolic process GO:0042180 84 0.027
vesicle localization GO:0051648 86 0.027
posttranscriptional gene silencing by rna GO:0035194 10 0.027
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.027
regulation of protein localization GO:0032880 231 0.027
carbohydrate metabolic process GO:0005975 230 0.027
transmembrane transport GO:0055085 412 0.027
stem cell differentiation GO:0048863 268 0.027
response to unfolded protein GO:0006986 21 0.026
monosaccharide metabolic process GO:0005996 106 0.026
carbohydrate biosynthetic process GO:0016051 74 0.026
dna metabolic process GO:0006259 303 0.026
regulation of growth hormone receptor signaling pathway GO:0060398 3 0.026
gland development GO:0048732 330 0.026
ribonucleoside metabolic process GO:0009119 245 0.025
positive regulation of cell death GO:0010942 224 0.025
female sex differentiation GO:0046660 84 0.025
mitochondrial fusion GO:0008053 9 0.025
establishment of protein localization to organelle GO:0072594 118 0.025
meiotic nuclear division GO:0007126 115 0.024
positive regulation of protein modification process GO:0031401 299 0.024
positive regulation of secretion GO:0051047 130 0.024
glycogen cell differentiation involved in embryonic placenta development GO:0060709 1 0.024
negative regulation of neuron death GO:1901215 98 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
ribonucleoside monophosphate metabolic process GO:0009161 80 0.023
alpha beta t cell activation GO:0046631 91 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
neuron migration GO:0001764 122 0.023
regulation of protein maturation GO:1903317 96 0.022
development of primary female sexual characteristics GO:0046545 73 0.022
atp catabolic process GO:0006200 55 0.022
rna processing GO:0006396 105 0.022
autophagy GO:0006914 45 0.022
response to starvation GO:0042594 65 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
response to acid chemical GO:0001101 111 0.022
glucose homeostasis GO:0042593 128 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
carboxylic acid transport GO:0046942 100 0.021
protein maturation GO:0051604 176 0.021
t cell activation involved in immune response GO:0002286 43 0.021
regulation of translation GO:0006417 71 0.021
protein oligomerization GO:0051259 67 0.021
response to reactive oxygen species GO:0000302 56 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.021
regulation of fat cell differentiation GO:0045598 81 0.021
negative regulation of protein maturation GO:1903318 79 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
labyrinthine layer development GO:0060711 49 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.020
regulation of secretion by cell GO:1903530 249 0.020
response to decreased oxygen levels GO:0036293 59 0.020
defecation GO:0030421 1 0.020
gene silencing GO:0016458 38 0.019
anion transport GO:0006820 177 0.019
response to temperature stimulus GO:0009266 55 0.019
mesenchymal cell development GO:0014031 93 0.019
embryonic placenta development GO:0001892 98 0.019
placenta development GO:0001890 140 0.019
rho protein signal transduction GO:0007266 32 0.019
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.019
negative regulation of protein modification process GO:0031400 163 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
regulation of secretion GO:0051046 274 0.019
response to light stimulus GO:0009416 135 0.018
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.018
development of primary male sexual characteristics GO:0046546 88 0.018
nucleoside monophosphate catabolic process GO:0009125 59 0.018
sertoli cell differentiation GO:0060008 18 0.018
stem cell proliferation GO:0072089 117 0.018
negative regulation of fatty acid transport GO:2000192 1 0.018
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.018
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.018
regulation of gluconeogenesis GO:0006111 30 0.018
regulation of cell cycle GO:0051726 281 0.018
ear development GO:0043583 200 0.018
organic acid transport GO:0015849 101 0.018
response to organic cyclic compound GO:0014070 198 0.018
male sex differentiation GO:0046661 109 0.017
protein processing GO:0016485 163 0.017
cellular amino acid metabolic process GO:0006520 103 0.017
carbohydrate homeostasis GO:0033500 128 0.017
wnt signaling pathway GO:0016055 188 0.017
ribosomal small subunit biogenesis GO:0042274 4 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.017
negative regulation of translational initiation GO:0045947 4 0.016
positive regulation of interleukin 13 secretion GO:2000667 1 0.016
glycogen metabolic process GO:0005977 32 0.016
response to inorganic substance GO:0010035 96 0.016
negative regulation of mitochondrion organization GO:0010823 9 0.016
response to oxidative stress GO:0006979 123 0.016
negative regulation of nucleoside metabolic process GO:0045978 11 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
protein polyubiquitination GO:0000209 33 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
cell type specific apoptotic process GO:0097285 268 0.016
photoreceptor cell differentiation GO:0046530 52 0.016
negative regulation of organelle organization GO:0010639 90 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
amine metabolic process GO:0009308 45 0.016
gliogenesis GO:0042063 141 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
mitotic cell cycle process GO:1903047 159 0.016
rna splicing GO:0008380 54 0.015
response to peptide hormone GO:0043434 127 0.015
neuronal action potential GO:0019228 54 0.015
ncrna processing GO:0034470 26 0.015
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.015
epithelial cell proliferation GO:0050673 174 0.015
apoptotic signaling pathway GO:0097190 306 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
cytoplasmic mrna processing body assembly GO:0033962 6 0.015
regulation of protein kinase activity GO:0045859 232 0.014
regulation of t cell differentiation in thymus GO:0033081 24 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
response to peptide GO:1901652 136 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
epithelial cell development GO:0002064 159 0.014
positive regulation of protein catabolic process GO:0045732 60 0.014
multicellular organismal signaling GO:0035637 91 0.014
sensory organ morphogenesis GO:0090596 242 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
hair cycle GO:0042633 90 0.014
positive regulation of cell motility GO:2000147 116 0.014
organ growth GO:0035265 117 0.014
negative regulation of proteolysis GO:0045861 74 0.014
atp metabolic process GO:0046034 75 0.013
macromolecular complex disassembly GO:0032984 43 0.013
mapk cascade GO:0000165 281 0.013
regulation of actin filament based process GO:0032970 99 0.013
positive regulation of ruffle assembly GO:1900029 1 0.013
response to radiation GO:0009314 165 0.013
locomotory behavior GO:0007626 195 0.013
regulation of protein transport GO:0051223 163 0.013
regulation of feeding behavior GO:0060259 3 0.013
determination of adult lifespan GO:0008340 11 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
regulation of protein secretion GO:0050708 82 0.013
positive regulation of wnt signaling pathway GO:0030177 45 0.013
cellular response to external stimulus GO:0071496 88 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
regulation of cell motility GO:2000145 236 0.013
nuclear transport GO:0051169 139 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.012
protein k63 linked ubiquitination GO:0070534 6 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
homeostasis of number of cells GO:0048872 210 0.012
organelle localization GO:0051640 179 0.012
stem cell development GO:0048864 219 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
positive regulation of interleukin 13 production GO:0032736 4 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
organic anion transport GO:0015711 137 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
brain segmentation GO:0035284 3 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
synaptic transmission GO:0007268 329 0.012
nucleoside metabolic process GO:0009116 246 0.012
fertilization GO:0009566 127 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
regulation of organelle organization GO:0033043 289 0.012
cellular response to oxidative stress GO:0034599 76 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
response to amino acid GO:0043200 37 0.012
regulation of organ growth GO:0046620 61 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
maintenance of location GO:0051235 89 0.011
histone h4 k16 acetylation GO:0043984 3 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
positive regulation of interleukin 5 secretion GO:2000664 1 0.011
response to extracellular stimulus GO:0009991 127 0.011
single organism nuclear import GO:1902593 95 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of jnk cascade GO:0046328 62 0.011
male gonad development GO:0008584 88 0.011
gluconeogenesis GO:0006094 39 0.011
cellular homeostasis GO:0019725 240 0.011
cellular response to starvation GO:0009267 57 0.011
protein localization to membrane GO:0072657 108 0.011
protein import into nucleus GO:0006606 95 0.011
metencephalon development GO:0022037 89 0.011
interleukin 5 secretion GO:0072603 2 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
inflammatory response GO:0006954 244 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
meiotic cell cycle GO:0051321 122 0.011
cell maturation GO:0048469 127 0.011
negative regulation of ion transport GO:0043271 28 0.011
activation of ral gtpase activity GO:0032859 3 0.011
amino acid transport GO:0006865 61 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
rna modification GO:0009451 20 0.011
cyclic purine nucleotide metabolic process GO:0052652 43 0.010
protein localization to nucleus GO:0034504 121 0.010
hindbrain development GO:0030902 128 0.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.010
alpha beta t cell differentiation GO:0046632 69 0.010
spindle organization GO:0007051 28 0.010
hatching GO:0035188 4 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
microtubule based process GO:0007017 236 0.010
follicle stimulating hormone signaling pathway GO:0042699 3 0.010
positive regulation of cell migration GO:0030335 109 0.010
positive regulation of cell activation GO:0050867 158 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
cell activation involved in immune response GO:0002263 126 0.010
mesenchyme development GO:0060485 152 0.010
activation of adenylate cyclase activity GO:0007190 4 0.010
hair follicle development GO:0001942 85 0.010
skeletal muscle cell differentiation GO:0035914 66 0.010

Psmd3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.019
charcot marie tooth disease type 2 DOID:0050539 0 0.019
disease of anatomical entity DOID:7 0 0.019
charcot marie tooth disease DOID:10595 0 0.019
nervous system disease DOID:863 0 0.019
neuropathy DOID:870 0 0.019
central nervous system disease DOID:331 0 0.016