Mus musculus

0 known processes

Defb35

defensin beta 35

(Aliases: BD-35)

Defb35 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.257
regulation of cellular ketone metabolic process GO:0010565 66 0.176
carbohydrate metabolic process GO:0005975 230 0.120
cellular amino acid metabolic process GO:0006520 103 0.116
cell type specific apoptotic process GO:0097285 268 0.105
apoptotic signaling pathway GO:0097190 306 0.102
regulation of cellular amino acid metabolic process GO:0006521 5 0.101
regulation of cellular amine metabolic process GO:0033238 20 0.097
cellular response to cytokine stimulus GO:0071345 189 0.095
regulation of cell cycle GO:0051726 281 0.080
cellular amine metabolic process GO:0044106 44 0.078
neuromuscular process GO:0050905 99 0.074
immune effector process GO:0002252 321 0.062
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
epithelial cell development GO:0002064 159 0.054
camera type eye development GO:0043010 266 0.053
regulation of homeostatic process GO:0032844 182 0.050
regulation of neuron differentiation GO:0045664 281 0.050
regulation of hydrolase activity GO:0051336 246 0.047
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.045
transmembrane transport GO:0055085 412 0.044
amine metabolic process GO:0009308 45 0.044
regulation of secretion by cell GO:1903530 249 0.041
macromolecule catabolic process GO:0009057 281 0.041
positive regulation of neuron differentiation GO:0045666 141 0.039
regulation of metal ion transport GO:0010959 106 0.039
sequestering of calcium ion GO:0051208 18 0.039
leukocyte differentiation GO:0002521 342 0.039
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.039
extrinsic apoptotic signaling pathway GO:0097191 126 0.037
cell growth GO:0016049 130 0.037
insulin secretion GO:0030073 89 0.037
regulation of proteolysis GO:0030162 164 0.037
peptidyl amino acid modification GO:0018193 336 0.036
mitotic cell cycle GO:0000278 195 0.036
cellular response to lipid GO:0071396 145 0.035
intrinsic apoptotic signaling pathway GO:0097193 132 0.034
axonogenesis GO:0007409 274 0.034
canonical wnt signaling pathway GO:0060070 130 0.034
developmental growth involved in morphogenesis GO:0060560 138 0.033
cellular lipid metabolic process GO:0044255 323 0.031
embryonic placenta development GO:0001892 98 0.031
protein modification by small protein conjugation or removal GO:0070647 207 0.030
cytoplasmic transport GO:0016482 234 0.030
regulation of lymphocyte mediated immunity GO:0002706 84 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
gliogenesis GO:0042063 141 0.030
regulation of binding GO:0051098 111 0.030
regulation of protein localization GO:0032880 231 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
circadian rhythm GO:0007623 114 0.028
cellular response to external stimulus GO:0071496 88 0.028
regulation of cell projection organization GO:0031344 206 0.028
negative regulation of immune system process GO:0002683 209 0.028
muscle tissue development GO:0060537 308 0.028
striated muscle tissue development GO:0014706 293 0.028
defense response to bacterium GO:0042742 119 0.028
inflammatory response GO:0006954 244 0.028
male anatomical structure morphogenesis GO:0090598 4 0.028
positive regulation of cytokine production GO:0001819 174 0.027
negative regulation of molecular function GO:0044092 258 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
heterocycle catabolic process GO:0046700 280 0.026
glycoprotein biosynthetic process GO:0009101 89 0.026
cellular response to steroid hormone stimulus GO:0071383 33 0.026
placenta development GO:0001890 140 0.026
adaptive immune response GO:0002250 155 0.026
calcium ion transport GO:0006816 159 0.026
negative regulation of cell fate specification GO:0009996 4 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
inorganic cation transmembrane transport GO:0098662 207 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.024
regulation of anatomical structure size GO:0090066 178 0.024
regulation of system process GO:0044057 200 0.024
peptidyl tyrosine modification GO:0018212 145 0.024
regulation of t cell activation GO:0050863 170 0.023
regulation of mapk cascade GO:0043408 248 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
synaptic transmission GO:0007268 329 0.023
lymphocyte differentiation GO:0030098 242 0.023
cation transmembrane transport GO:0098655 266 0.022
regulation of ion transport GO:0043269 215 0.022
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.022
wnt signaling pathway GO:0016055 188 0.022
regulation of transmembrane transport GO:0034762 128 0.022
ossification GO:0001503 216 0.022
chromatin modification GO:0016568 187 0.022
negative regulation of cell activation GO:0050866 111 0.022
sequestering of metal ion GO:0051238 19 0.022
organic cyclic compound catabolic process GO:1901361 295 0.021
chromatin organization GO:0006325 206 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
rac protein signal transduction GO:0016601 13 0.021
regulation of leukocyte differentiation GO:1902105 159 0.021
regulation of cell activation GO:0050865 289 0.021
nitrogen compound transport GO:0071705 271 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
membrane lipid metabolic process GO:0006643 53 0.020
stem cell maintenance GO:0019827 130 0.020
sensory perception of sound GO:0007605 97 0.020
establishment of neuroblast polarity GO:0045200 1 0.020
compound eye development GO:0048749 1 0.020
respiratory system development GO:0060541 190 0.020
aromatic compound catabolic process GO:0019439 286 0.020
neuron death GO:0070997 154 0.020
locomotory behavior GO:0007626 195 0.020
ras protein signal transduction GO:0007265 77 0.020
nuclear division GO:0000280 158 0.019
smoothened signaling pathway GO:0007224 105 0.019
regulation of protein kinase activity GO:0045859 232 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
appendage development GO:0048736 166 0.019
protein polymerization GO:0051258 57 0.019
calcium ion transmembrane transport GO:0070588 85 0.019
glial cell differentiation GO:0010001 131 0.019
asymmetric stem cell division GO:0098722 3 0.019
positive regulation of cell development GO:0010720 237 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
meiotic cell cycle process GO:1903046 77 0.019
negative regulation of organelle organization GO:0010639 90 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
regulation of secretion GO:0051046 274 0.018
regulation of ion homeostasis GO:2000021 64 0.018
sphingolipid metabolic process GO:0006665 45 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
learning or memory GO:0007611 148 0.018
establishment or maintenance of neuroblast polarity GO:0045196 1 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
epidermis development GO:0008544 187 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
regulation of t cell proliferation GO:0042129 92 0.018
intracellular protein transport GO:0006886 204 0.018
regulation of neuron projection development GO:0010975 169 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.017
protein localization to organelle GO:0033365 185 0.017
positive regulation of nervous system development GO:0051962 221 0.017
wound healing GO:0042060 157 0.017
appendage morphogenesis GO:0035107 149 0.017
ear development GO:0043583 200 0.017
organelle localization GO:0051640 179 0.017
cerebral cortex development GO:0021987 86 0.017
neuron projection extension GO:1990138 64 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
dendrite development GO:0016358 115 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
cellular chemical homeostasis GO:0055082 215 0.017
regulation of cellular component size GO:0032535 121 0.017
membrane lipid biosynthetic process GO:0046467 32 0.017
nucleotide catabolic process GO:0009166 217 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
sensory perception GO:0007600 245 0.017
regulation of extent of cell growth GO:0061387 52 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
mapk cascade GO:0000165 281 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
cytokine production GO:0001816 319 0.016
response to inorganic substance GO:0010035 96 0.016
regulation of organelle organization GO:0033043 289 0.016
regulation of peptidase activity GO:0052547 96 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
nuclear transport GO:0051169 139 0.016
protein catabolic process GO:0030163 221 0.016
maintenance of location GO:0051235 89 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
urogenital system development GO:0001655 261 0.015
nucleotide metabolic process GO:0009117 332 0.015
organelle fission GO:0048285 170 0.015
cell adhesion GO:0007155 329 0.015
nucleoside metabolic process GO:0009116 246 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
oxidation reduction process GO:0055114 342 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
carbohydrate homeostasis GO:0033500 128 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
embryonic genitalia morphogenesis GO:0030538 4 0.015
cognition GO:0050890 149 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
divalent inorganic cation transport GO:0072511 178 0.015
connective tissue development GO:0061448 179 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
regulation of cell cycle process GO:0010564 160 0.014
lipid localization GO:0010876 126 0.014
positive regulation of map kinase activity GO:0043406 84 0.014
retina development in camera type eye GO:0060041 119 0.014
regulation of cell size GO:0008361 72 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
asymmetric neuroblast division GO:0055059 1 0.014
nucleoside catabolic process GO:0009164 206 0.014
membrane organization GO:0061024 245 0.014
response to monosaccharide GO:0034284 67 0.014
organophosphate catabolic process GO:0046434 232 0.014
skeletal system morphogenesis GO:0048705 203 0.014
meiotic nuclear division GO:0007126 115 0.014
sensory perception of mechanical stimulus GO:0050954 107 0.014
skeletal system development GO:0001501 356 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of cell growth GO:0001558 91 0.014
neuron apoptotic process GO:0051402 142 0.014
digestive system development GO:0055123 200 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
stem cell development GO:0048864 219 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
negative regulation of cell cycle GO:0045786 123 0.013
response to epidermal growth factor GO:0070849 4 0.013
regulation of protein complex assembly GO:0043254 83 0.013
cation transport GO:0006812 399 0.013
peptidyl lysine modification GO:0018205 77 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
positive regulation of cell cycle GO:0045787 92 0.013
regulation of actin filament based process GO:0032970 99 0.013
myeloid cell differentiation GO:0030099 233 0.013
intestinal epithelial structure maintenance GO:0060729 4 0.013
neural precursor cell proliferation GO:0061351 121 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
single organism cell adhesion GO:0098602 156 0.013
purine containing compound catabolic process GO:0072523 213 0.013
leukocyte mediated immunity GO:0002443 174 0.013
lipid transport GO:0006869 98 0.013
tissue homeostasis GO:0001894 115 0.013
regulation of response to wounding GO:1903034 189 0.013
positive regulation of protein modification process GO:0031401 299 0.013
ion transmembrane transport GO:0034220 361 0.013
calcium ion homeostasis GO:0055074 127 0.013
glycerolipid metabolic process GO:0046486 122 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
regulation of hormone levels GO:0010817 211 0.013
developmental cell growth GO:0048588 84 0.013
homeostasis of number of cells GO:0048872 210 0.013
axon guidance GO:0007411 141 0.013
response to organic cyclic compound GO:0014070 198 0.012
molting cycle GO:0042303 90 0.012
t cell activation GO:0042110 289 0.012
negative regulation of protein complex disassembly GO:0043242 22 0.012
cell fate commitment GO:0045165 210 0.012
male genitalia morphogenesis GO:0048808 4 0.012
covalent chromatin modification GO:0016569 163 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
meiotic cell cycle GO:0051321 122 0.012
kidney development GO:0001822 213 0.012
lens development in camera type eye GO:0002088 62 0.012
response to metal ion GO:0010038 47 0.012
fat cell differentiation GO:0045444 160 0.012
rhythmic process GO:0048511 174 0.012
alcohol metabolic process GO:0006066 116 0.012
purine containing compound metabolic process GO:0072521 311 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
regulation of feeding behavior GO:0060259 3 0.012
mitotic cell cycle process GO:1903047 159 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.012
lymphocyte proliferation GO:0046651 164 0.012
digestive tract morphogenesis GO:0048546 147 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
sulfur compound metabolic process GO:0006790 100 0.012
learning GO:0007612 98 0.012
protein ubiquitination GO:0016567 171 0.012
regulation of protein processing GO:0070613 96 0.012
cell cell signaling involved in lung development GO:0060495 1 0.012
pancreas development GO:0031016 57 0.012
regulation of phospholipid biosynthetic process GO:0071071 3 0.012
notch signaling pathway GO:0007219 71 0.011
macromolecular complex disassembly GO:0032984 43 0.011
regulation of adaptive immune response GO:0002819 90 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
protein localization to membrane GO:0072657 108 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
response to acid chemical GO:0001101 111 0.011
glial cell development GO:0021782 54 0.011
b cell activation GO:0042113 161 0.011
regulation of canonical wnt signaling pathway GO:0060828 82 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of map kinase activity GO:0043405 120 0.011
histone modification GO:0016570 159 0.011
cation homeostasis GO:0055080 212 0.011
positive regulation of proteolysis GO:0045862 85 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
macromolecule methylation GO:0043414 120 0.011
actin cytoskeleton organization GO:0030036 220 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
negative regulation of mesodermal cell fate specification GO:0042662 3 0.011
mesodermal cell migration GO:0008078 4 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
epithelial tube formation GO:0072175 130 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
cellular homeostasis GO:0019725 240 0.011
negative regulation of cell development GO:0010721 169 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
digestive tract development GO:0048565 190 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of auditory receptor cell differentiation GO:0045607 4 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
regulation of neuron death GO:1901214 134 0.011
respiratory tube development GO:0030323 167 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
negative regulation of t cell activation GO:0050868 65 0.010
adult locomotory behavior GO:0008344 91 0.010
protein localization to nucleus GO:0034504 121 0.010
regulation of protein depolymerization GO:1901879 26 0.010
regulation of muscle tissue development GO:1901861 97 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
chromosome segregation GO:0007059 48 0.010
rho protein signal transduction GO:0007266 32 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
regulation of protein transport GO:0051223 163 0.010
organic anion transport GO:0015711 137 0.010
endodermal cell fate specification GO:0001714 4 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
regulation of cell division GO:0051302 76 0.010
ribose phosphate metabolic process GO:0019693 291 0.010
developmental maturation GO:0021700 193 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
submandibular salivary gland formation GO:0060661 1 0.010

Defb35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
musculoskeletal system disease DOID:17 0 0.012
disease of metabolism DOID:0014667 0 0.012