|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.108
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.056
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.051
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.050
|
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.048
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.037
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.037
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.037
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.036
|
|
|
ripoptosome assembly involved in necroptotic process
|
GO:1901026 |
6 |
0.036
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.035
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.035
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.034
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.034
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.034
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.033
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.032
|
|
|
protein processing
|
GO:0016485 |
163 |
0.032
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.031
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.030
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.030
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.030
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.029
|
|
|
negative regulation of nlrp3 inflammasome complex assembly
|
GO:1900226 |
2 |
0.029
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.029
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.028
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.025
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.025
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.025
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.024
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.024
|
|
|
methylation
|
GO:0032259 |
134 |
0.024
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.024
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.023
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.023
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.023
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.022
|
|
|
positive regulation of viral entry into host cell
|
GO:0046598 |
3 |
0.022
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.021
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.021
|
|
|
neuron death
|
GO:0070997 |
154 |
0.021
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.021
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.021
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.021
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.021
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.020
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.020
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.020
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.019
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.019
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.019
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.019
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.019
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.019
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.019
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.019
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.019
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.019
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.019
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.018
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.018
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.018
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.018
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.018
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.018
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.018
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.018
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.018
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.018
|
|
|
gland development
|
GO:0048732 |
330 |
0.018
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.018
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.018
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.018
|
|
|
rna processing
|
GO:0006396 |
105 |
0.018
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.017
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.017
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.017
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.017
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.017
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.017
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.017
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.017
|
|
|
regulation of nlrp3 inflammasome complex assembly
|
GO:1900225 |
4 |
0.017
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.017
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.017
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.017
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.017
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.017
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.017
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.017
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
3 |
0.017
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.017
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.016
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.016
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.016
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.016
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.016
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.016
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.016
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.016
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.016
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.016
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.016
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.016
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.015
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.015
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.015
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.015
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.015
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.015
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.015
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.015
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.015
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.014
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.014
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.014
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.014
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.014
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.014
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.014
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.014
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.014
|
|
|
zymogen inhibition
|
GO:0097341 |
1 |
0.014
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.014
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.013
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.013
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.013
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.013
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.013
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.013
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.013
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.013
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.013
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.013
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.013
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.013
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.013
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.013
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.013
|
|
|
protein localization to vacuole
|
GO:0072665 |
4 |
0.013
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.013
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.013
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.013
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.013
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.013
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.013
|
|
|
viral gene expression
|
GO:0019080 |
3 |
0.013
|
|
|
cellular response to estrogen stimulus
|
GO:0071391 |
12 |
0.013
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.013
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.013
|
|
|
dna modification
|
GO:0006304 |
50 |
0.013
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.013
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.013
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.012
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.012
|
|
|
cell division
|
GO:0051301 |
120 |
0.012
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.012
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.012
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.012
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.012
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.012
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.012
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.012
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.012
|
|
|
ossification
|
GO:0001503 |
216 |
0.012
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.012
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.012
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.012
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.012
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.012
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.012
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.012
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.012
|
|
|
cation transport
|
GO:0006812 |
399 |
0.012
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.012
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.012
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.012
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.012
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.012
|
|
|
regulation of viral transcription
|
GO:0046782 |
3 |
0.012
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.012
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.011
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.011
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.011
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.011
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.011
|
|
|
viral transcription
|
GO:0019083 |
3 |
0.011
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.011
|
|
|
detection of other organism
|
GO:0098543 |
8 |
0.011
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.011
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.011
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.011
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.011
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.011
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.011
|
|
|
positive regulation of viral genome replication
|
GO:0045070 |
2 |
0.011
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.011
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.011
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.011
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.011
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.011
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.011
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.011
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.011
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.011
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.011
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.011
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.011
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.010
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.010
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.010
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.010
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.010
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.010
|
|
|
male genitalia morphogenesis
|
GO:0048808 |
4 |
0.010
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.010
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.010
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.010
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.010
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.010
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.010
|
|
|
inhibition of cysteine type endopeptidase activity involved in apoptotic process
|
GO:1990001 |
1 |
0.010
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.010
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.010
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.010
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.010
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.010
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.010
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.010
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.010
|
|