|
|
cation transport
|
GO:0006812 |
399 |
0.496
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.462
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.374
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.302
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.272
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.258
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.253
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.244
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.242
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.229
|
Fly |
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.220
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.212
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.209
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.204
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.204
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.202
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.187
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.176
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.175
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.173
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.173
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.166
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.165
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.159
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.159
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.158
|
Worm |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.155
|
Worm |
|
|
exocytosis
|
GO:0006887 |
121 |
0.151
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.140
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.139
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.136
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.136
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.125
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.124
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.123
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.121
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.120
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.120
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.116
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.116
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.115
|
Worm |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.115
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.114
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.113
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.113
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.112
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.111
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.110
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.110
|
Fly |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.108
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.107
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.107
|
Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.103
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.103
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.103
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.100
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.100
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.098
|
Mouse Fly |
|
|
vesicle organization
|
GO:0016050 |
60 |
0.098
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.097
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.097
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.096
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.095
|
|
|
|
synaptic vesicle fusion to presynaptic membrane
|
GO:0031629 |
3 |
0.095
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.095
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.094
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.094
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.094
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.093
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.093
|
|
|
|
learning
|
GO:0007612 |
98 |
0.093
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.092
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.091
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.090
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.088
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.088
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.086
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.086
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.085
|
Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.085
|
Mouse |
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.085
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.084
|
Fly |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.084
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.083
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.082
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.080
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.080
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.079
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.078
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.078
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.078
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.076
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.076
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.076
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.075
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.075
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.074
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.074
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.074
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.074
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.073
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.073
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.073
|
Fly |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.072
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.072
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.072
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.071
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.071
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.071
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.071
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.071
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.069
|
Mouse Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.068
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.068
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.067
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.066
|
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.065
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.065
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.065
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.064
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.062
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.062
|
Fly |
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.062
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.061
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.060
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.060
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.059
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.057
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.056
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.055
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.055
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.054
|
Mouse |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.054
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.054
|
Yeast Worm Fly |
|
|
heart process
|
GO:0003015 |
94 |
0.053
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.053
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.052
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.051
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.051
|
Mouse |
|
|
neuron death
|
GO:0070997 |
154 |
0.051
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.050
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.049
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.049
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.049
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.048
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.048
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.047
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.047
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.047
|
|
|
|
male meiosis
|
GO:0007140 |
37 |
0.046
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.045
|
Fly |
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.045
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.045
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.044
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.044
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.044
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.044
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.044
|
Fly |
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.044
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.044
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.044
|
|
|
|
synaptic vesicle priming
|
GO:0016082 |
8 |
0.043
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.043
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.042
|
Mouse Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.042
|
Fly |
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.042
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.042
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
71 |
0.042
|
|
|
|
relaxation of muscle
|
GO:0090075 |
18 |
0.042
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.042
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.041
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.041
|
Worm |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.041
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.041
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.040
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.040
|
Fly |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.040
|
Mouse |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.039
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.039
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.038
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.038
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.038
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.037
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.037
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.037
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.037
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.036
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.036
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.036
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.036
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.035
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.035
|
Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.035
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.035
|
Fly |
|
|
sensory perception of light stimulus
|
GO:0050953 |
54 |
0.035
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.034
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.034
|
|
|
|
activation of meiosis involved in egg activation
|
GO:0060466 |
2 |
0.034
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.034
|
Mouse |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.034
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.034
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.034
|
Mouse |
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.033
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.033
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.033
|
Mouse |
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.033
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.032
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.032
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.032
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.032
|
Fly |
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.031
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.031
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.031
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.031
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.030
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.030
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.030
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.030
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.030
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.029
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.029
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.029
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.029
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.029
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.029
|
|
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.029
|
|
|
|
response to calcium ion
|
GO:0051592 |
20 |
0.029
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.028
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.028
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.028
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.028
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.028
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.028
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.028
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.028
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.027
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.027
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.027
|
Fly |
|
|
cell maturation
|
GO:0048469 |
127 |
0.027
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.027
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.027
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.026
|
Worm |
|
|
melanin metabolic process
|
GO:0006582 |
12 |
0.026
|
Fly |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.026
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.026
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.026
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.026
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.026
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.026
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.026
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.025
|
|
|
|
organelle fusion
|
GO:0048284 |
28 |
0.025
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.025
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.025
|
Mouse |
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.025
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.025
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.025
|
|
|
|
potassium ion homeostasis
|
GO:0055075 |
4 |
0.025
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.025
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.025
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.024
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.024
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.024
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.024
|
Mouse |
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.024
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.024
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.024
|
Fly |
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.024
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.024
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.024
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.023
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.023
|
Mouse |
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.023
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.023
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.023
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.023
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.023
|
|
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.023
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.023
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.023
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.022
|
Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.022
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
3 |
0.022
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.022
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.022
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.022
|
Mouse |
|
|
organic anion transport
|
GO:0015711 |
137 |
0.022
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
35 |
0.022
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.022
|
|
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.022
|
Fly |
|
|
behavioral defense response
|
GO:0002209 |
28 |
0.021
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.021
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.021
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.021
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.021
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.021
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.021
|
|
|
|
mating
|
GO:0007618 |
27 |
0.021
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.021
|
|
|
|
positive regulation of schwann cell proliferation
|
GO:0010625 |
1 |
0.021
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.021
|
Fly |
|
|
ossification
|
GO:0001503 |
216 |
0.020
|
Mouse |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.020
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.020
|
|
|
|
neurofilament cytoskeleton organization
|
GO:0060052 |
10 |
0.020
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.020
|
|
|
|
sa node cell to atrial cardiac muscle cell signalling
|
GO:0086018 |
4 |
0.020
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.020
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.020
|
Fly |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.020
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.020
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.020
|
Mouse |
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.020
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.020
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.020
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.020
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.020
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.019
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.019
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.019
|
Mouse |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.019
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.019
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.019
|
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.019
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.019
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.019
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.019
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.019
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.019
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.019
|
|
|
|
sa node cell action potential
|
GO:0086015 |
4 |
0.019
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.019
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.019
|
|
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
23 |
0.019
|
|
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
2 |
0.019
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.019
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.018
|
|
|
|
response to heat
|
GO:0009408 |
27 |
0.018
|
Yeast Worm Fly |
|
|
innate immune response
|
GO:0045087 |
157 |
0.018
|
Fly |
|
|
establishment of glial blood brain barrier
|
GO:0060857 |
2 |
0.018
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.018
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.018
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.018
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.018
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.018
|
Mouse |
|
|
methylation
|
GO:0032259 |
134 |
0.018
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.018
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.018
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.018
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.018
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.018
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.018
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.018
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.018
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.017
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.017
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.017
|
Yeast |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.017
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.017
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.017
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.017
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.017
|
Yeast |
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.017
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.017
|
Mouse |
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.017
|
|
|
|
regulation of neurotransmitter uptake
|
GO:0051580 |
6 |
0.017
|
|
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.017
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.017
|
Fly |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.017
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.017
|
Mouse |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.017
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.017
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.017
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.017
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.017
|
Fly |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.017
|
Mouse |
|
|
snare complex disassembly
|
GO:0035494 |
2 |
0.017
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.017
|
Zebrafish |
|
|
cell growth
|
GO:0016049 |
130 |
0.016
|
Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.016
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.016
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.016
|
Mouse |
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.016
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.016
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.016
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.016
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.016
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.016
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.016
|
Mouse |
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.016
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.016
|
Mouse |
|
|
courtship behavior
|
GO:0007619 |
5 |
0.016
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
43 |
0.016
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.016
|
Fly |
|
|
positive regulation of cardiac muscle contraction
|
GO:0060452 |
2 |
0.016
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.016
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.016
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.016
|
|
|
|
directional locomotion
|
GO:0033058 |
3 |
0.016
|
|
|
|
regulation of cell projection size
|
GO:0032536 |
6 |
0.016
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
32 |
0.016
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.016
|
Mouse |
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.016
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.016
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.015
|
Fly |
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.015
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.015
|
|
|
|
chloride transmembrane transport
|
GO:1902476 |
24 |
0.015
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.015
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.015
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.015
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.015
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.015
|
Mouse |
|
|
neurotransmitter uptake
|
GO:0001504 |
14 |
0.015
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.015
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.015
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.015
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.015
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.015
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.015
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.015
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.015
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.015
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.015
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.015
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.015
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.015
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.015
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.015
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.015
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.015
|
|
|
|
negative regulation of synapse maturation
|
GO:2000297 |
2 |
0.015
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.015
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.015
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.015
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.014
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.014
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.014
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.014
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.014
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.014
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.014
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.014
|
|
|
|
localization within membrane
|
GO:0051668 |
4 |
0.014
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.014
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.014
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.014
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.014
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.014
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.014
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.014
|
Mouse |
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.014
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.014
|
|
|
|
intermediate filament bundle assembly
|
GO:0045110 |
3 |
0.014
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.014
|
|
|
|
regulation of rac protein signal transduction
|
GO:0035020 |
19 |
0.014
|
|
|
|
membrane tubulation
|
GO:0097320 |
4 |
0.014
|
|
|
|
negative regulation of rac protein signal transduction
|
GO:0035021 |
4 |
0.014
|
|
|
|
response to histamine
|
GO:0034776 |
1 |
0.014
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.014
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.014
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.014
|
|
|
|
membrane depolarization during sa node cell action potential
|
GO:0086046 |
2 |
0.014
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.014
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.014
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.013
|
Yeast |
|
|
autophagy
|
GO:0006914 |
45 |
0.013
|
Fly |
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.013
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.013
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.013
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
57 |
0.013
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.013
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.013
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.013
|
Mouse |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.013
|
|
|
|
microtubule polymerization
|
GO:0046785 |
12 |
0.013
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.013
|
Yeast Worm |
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
29 |
0.013
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.013
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.013
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.013
|
Fly |
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.013
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
4 |
0.013
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.013
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
25 |
0.013
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.013
|
|
|
|
regulation of synaptic vesicle priming
|
GO:0010807 |
4 |
0.013
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.013
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.013
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.013
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.013
|
Mouse |
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.013
|
|
|
|
ribonucleoprotein complex disassembly
|
GO:0032988 |
3 |
0.013
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.013
|
|
