Mus musculus

67 known processes

Pde1b

phosphodiesterase 1B, Ca2+-calmodulin dependent

(Aliases: 63kDa,Pde1b1)

Pde1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine nucleotide metabolic process GO:0006163 302 0.807
Mouse Rat
nucleotide metabolic process GO:0009117 332 0.778
Mouse Rat
carbohydrate derivative catabolic process GO:1901136 231 0.719
Mouse Rat
ribonucleotide catabolic process GO:0009261 208 0.657
Mouse Rat
purine ribonucleotide metabolic process GO:0009150 290 0.655
Mouse Rat
regulation of cell projection organization GO:0031344 206 0.651
nucleoside phosphate metabolic process GO:0006753 338 0.649
Mouse Rat
guanosine containing compound metabolic process GO:1901068 144 0.607
ribonucleoside triphosphate catabolic process GO:0009203 199 0.583
nucleoside metabolic process GO:0009116 246 0.571
synaptic transmission GO:0007268 329 0.565
ras protein signal transduction GO:0007265 77 0.558
regulation of nucleoside metabolic process GO:0009118 130 0.546
purine nucleotide catabolic process GO:0006195 211 0.544
Mouse Rat
positive regulation of gtp catabolic process GO:0033126 85 0.539
purine nucleoside metabolic process GO:0042278 241 0.519
nucleobase containing small molecule metabolic process GO:0055086 352 0.513
Mouse Rat
regulation of ras gtpase activity GO:0032318 88 0.477
nucleoside triphosphate catabolic process GO:0009143 205 0.476
axonogenesis GO:0007409 274 0.474
positive regulation of cellular catabolic process GO:0031331 148 0.470
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.457
organonitrogen compound catabolic process GO:1901565 264 0.452
Mouse Rat
regulation of cellular catabolic process GO:0031329 242 0.439
glycosyl compound catabolic process GO:1901658 206 0.433
regulation of cellular amine metabolic process GO:0033238 20 0.432
ion transmembrane transport GO:0034220 361 0.429
Mouse
amine metabolic process GO:0009308 45 0.417
aromatic compound catabolic process GO:0019439 286 0.414
Mouse Rat
regulation of purine nucleotide catabolic process GO:0033121 122 0.409
purine ribonucleoside catabolic process GO:0046130 205 0.409
positive regulation of nucleoside metabolic process GO:0045979 91 0.402
regulation of vesicle mediated transport GO:0060627 139 0.396
positive regulation of nucleotide catabolic process GO:0030813 88 0.393
purine ribonucleoside metabolic process GO:0046128 241 0.377
positive regulation of gtpase activity GO:0043547 85 0.375
small gtpase mediated signal transduction GO:0007264 97 0.374
ribonucleoside metabolic process GO:0009119 245 0.369
cellular amine metabolic process GO:0044106 44 0.368
guanosine containing compound catabolic process GO:1901069 144 0.363
gtp metabolic process GO:0046039 144 0.351
nucleotide catabolic process GO:0009166 217 0.343
Mouse Rat
nucleoside triphosphate metabolic process GO:0009141 230 0.335
nucleoside phosphate catabolic process GO:1901292 222 0.335
Mouse Rat
actin cytoskeleton organization GO:0030036 220 0.323
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.322
purine containing compound metabolic process GO:0072521 311 0.305
Mouse Rat
ribonucleoside catabolic process GO:0042454 206 0.302
purine nucleoside catabolic process GO:0006152 205 0.295
gtp catabolic process GO:0006184 143 0.294
nucleoside catabolic process GO:0009164 206 0.289
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.289
regulation of membrane potential GO:0042391 192 0.282
regulation of purine nucleotide metabolic process GO:1900542 169 0.281
visual behavior GO:0007632 45 0.279
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.278
ribonucleotide metabolic process GO:0009259 291 0.275
Mouse Rat
regulation of cell motility GO:2000145 236 0.274
purine nucleoside triphosphate catabolic process GO:0009146 203 0.274
neuron projection extension GO:1990138 64 0.274
purine nucleoside triphosphate metabolic process GO:0009144 226 0.266
organophosphate catabolic process GO:0046434 232 0.258
Mouse Rat
regulation of transmembrane transport GO:0034762 128 0.253
Mouse
regulation of neuron differentiation GO:0045664 281 0.253
regulation of neuron projection development GO:0010975 169 0.250
regulation of nucleotide metabolic process GO:0006140 169 0.248
regulation of rho gtpase activity GO:0032319 58 0.245
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.243
purine containing compound catabolic process GO:0072523 213 0.241
Mouse Rat
regulation of protein kinase activity GO:0045859 232 0.232
regulation of gtp catabolic process GO:0033124 113 0.229
positive regulation of ras gtpase activity GO:0032320 65 0.228
positive regulation of rho gtpase activity GO:0032321 41 0.226
asymmetric neuroblast division GO:0055059 1 0.214
inorganic ion transmembrane transport GO:0098660 234 0.213
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.208
Mouse
glycosyl compound metabolic process GO:1901657 246 0.207
ribonucleoside triphosphate metabolic process GO:0009199 220 0.204
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.204
regulation of ras protein signal transduction GO:0046578 114 0.197
microtubule based movement GO:0007018 84 0.197
establishment of vesicle localization GO:0051650 81 0.194
regulation of kinase activity GO:0043549 249 0.191
myelination in peripheral nervous system GO:0022011 19 0.188
negative regulation of protein metabolic process GO:0051248 282 0.185
Mouse
cation transmembrane transport GO:0098655 266 0.180
Mouse
regulation of hydrolase activity GO:0051336 246 0.175
positive regulation of cell migration GO:0030335 109 0.175
membrane tubulation GO:0097320 4 0.173
organic cyclic compound catabolic process GO:1901361 295 0.171
Mouse Rat
positive regulation of nucleotide metabolic process GO:0045981 114 0.167
regulation of transferase activity GO:0051338 263 0.164
cognition GO:0050890 149 0.163
asymmetric stem cell division GO:0098722 3 0.162
rho protein signal transduction GO:0007266 32 0.161
cell division GO:0051301 120 0.161
regulation of transporter activity GO:0032409 57 0.157
Mouse
circulatory system process GO:0003013 197 0.156
Mouse
leukocyte migration GO:0050900 124 0.155
Mouse
positive regulation of neuron projection development GO:0010976 79 0.155
response to radiation GO:0009314 165 0.149
locomotory behavior GO:0007626 195 0.149
negative regulation of molecular function GO:0044092 258 0.149
vesicle transport along microtubule GO:0047496 9 0.148
cellular nitrogen compound catabolic process GO:0044270 280 0.145
Mouse Rat
regulation of nucleotide catabolic process GO:0030811 122 0.144
negative regulation of phosphate metabolic process GO:0045936 184 0.144
Mouse
nitrogen compound transport GO:0071705 271 0.143
negative regulation of cellular protein metabolic process GO:0032269 247 0.142
Mouse
cellular metal ion homeostasis GO:0006875 151 0.138
Mouse
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.133
t cell activation GO:0042110 289 0.132
neuron projection guidance GO:0097485 141 0.132
multicellular organismal signaling GO:0035637 91 0.131
regulation of cell activation GO:0050865 289 0.131
regulation of mapk cascade GO:0043408 248 0.129
cell growth GO:0016049 130 0.129
positive regulation of protein modification process GO:0031401 299 0.128
vesicle localization GO:0051648 86 0.128
regulation of heart contraction GO:0008016 77 0.127
Mouse
regulation of anatomical structure size GO:0090066 178 0.127
regulation of secretion GO:0051046 274 0.124
negative regulation of protein phosphorylation GO:0001933 126 0.123
Mouse
memory GO:0007613 58 0.120
transmembrane transport GO:0055085 412 0.120
Mouse
negative regulation of cell motility GO:2000146 61 0.118
regulation of lymphocyte activation GO:0051249 240 0.117
inorganic cation transmembrane transport GO:0098662 207 0.115
Mouse
inflammatory response GO:0006954 244 0.115
negative regulation of protein modification process GO:0031400 163 0.114
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.113
central nervous system neuron differentiation GO:0021953 162 0.112
axon guidance GO:0007411 141 0.112
positive regulation of cell activation GO:0050867 158 0.111
positive regulation of lymphocyte activation GO:0051251 140 0.107
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.106
cellular ketone metabolic process GO:0042180 84 0.106
positive regulation of secretion GO:0051047 130 0.105
negative regulation of neuron death GO:1901215 98 0.104
cellular amino acid metabolic process GO:0006520 103 0.103
g protein coupled receptor signaling pathway GO:0007186 243 0.101
blood circulation GO:0008015 195 0.100
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.100
Mouse Rat
response to growth factor GO:0070848 198 0.099
glial cell development GO:0021782 54 0.099
developmental maturation GO:0021700 193 0.099
regulation of defense response GO:0031347 233 0.098
schwann cell development GO:0014044 22 0.098
nucleoside phosphate biosynthetic process GO:1901293 79 0.097
membrane organization GO:0061024 245 0.096
positive regulation of cell motility GO:2000147 116 0.094
cation transport GO:0006812 399 0.092
Mouse
developmental cell growth GO:0048588 84 0.092
negative regulation of neuron projection development GO:0010977 50 0.091
negative regulation of neuron apoptotic process GO:0043524 92 0.090
lymphocyte differentiation GO:0030098 242 0.089
protein kinase b signaling GO:0043491 74 0.088
exocytosis GO:0006887 121 0.088
adult locomotory behavior GO:0008344 91 0.088
myeloid leukocyte activation GO:0002274 83 0.087
cerebellar granule cell precursor tangential migration GO:0021935 1 0.086
positive regulation of secretion by cell GO:1903532 114 0.085
organelle localization GO:0051640 179 0.085
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.085
carbohydrate metabolic process GO:0005975 230 0.084
immune effector process GO:0002252 321 0.083
endocytosis GO:0006897 168 0.082
regulation of ion transport GO:0043269 215 0.082
Mouse
angiogenesis GO:0001525 201 0.082
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.082
neural precursor cell proliferation GO:0061351 121 0.081
epidermis development GO:0008544 187 0.081
regulation of neuron apoptotic process GO:0043523 122 0.081
regulation of ion transmembrane transport GO:0034765 119 0.081
Mouse
muscle cell differentiation GO:0042692 261 0.081
regulation of inflammatory response GO:0050727 147 0.081
regulation of cellular amino acid metabolic process GO:0006521 5 0.080
regulation of exocytosis GO:0017157 61 0.079
mapk cascade GO:0000165 281 0.079
actin filament organization GO:0007015 113 0.079
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.078
positive regulation of protein kinase b signaling GO:0051897 32 0.078
positive regulation of cellular amine metabolic process GO:0033240 5 0.078
regulation of rho protein signal transduction GO:0035023 71 0.077
regulation of cell migration GO:0030334 219 0.076
cellular chemical homeostasis GO:0055082 215 0.076
Mouse
organophosphate biosynthetic process GO:0090407 122 0.075
cation homeostasis GO:0055080 212 0.074
Mouse
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.074
gland development GO:0048732 330 0.074
negative regulation of cellular component organization GO:0051129 194 0.074
positive regulation of cell development GO:0010720 237 0.073
regulation of receptor activity GO:0010469 41 0.073
regulation of cell shape GO:0008360 39 0.072
cell chemotaxis GO:0060326 81 0.072
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.071
negative regulation of cell development GO:0010721 169 0.071
positive regulation of nervous system development GO:0051962 221 0.070
ribose phosphate metabolic process GO:0019693 291 0.070
Mouse Rat
positive regulation of neuron differentiation GO:0045666 141 0.069
cyclic nucleotide biosynthetic process GO:0009190 44 0.069
organonitrogen compound biosynthetic process GO:1901566 192 0.068
regulation of cellular component biogenesis GO:0044087 181 0.068
regulation of vasculature development GO:1901342 88 0.068
germ cell development GO:0007281 185 0.068
regulation of protein kinase b signaling GO:0051896 56 0.067
ribose phosphate biosynthetic process GO:0046390 59 0.066
cell adhesion GO:0007155 329 0.066
cellular response to growth factor stimulus GO:0071363 197 0.066
thymocyte migration GO:0072679 2 0.066
cellular homeostasis GO:0019725 240 0.066
Mouse
establishment of organelle localization GO:0051656 122 0.066
acetate ester transport GO:1901374 2 0.065
actin polymerization or depolymerization GO:0008154 54 0.065
neuron migration GO:0001764 122 0.065
regulation of intracellular transport GO:0032386 159 0.064
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.064
positive regulation of cell death GO:0010942 224 0.064
neurotransmitter secretion GO:0007269 62 0.064
negative regulation of intracellular signal transduction GO:1902532 167 0.063
positive regulation of protein phosphorylation GO:0001934 242 0.063
muscle tissue development GO:0060537 308 0.063
plasma membrane organization GO:0007009 90 0.063
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.063
chemotaxis GO:0006935 247 0.062
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.062
visual learning GO:0008542 44 0.062
lymphocyte proliferation GO:0046651 164 0.061
female gamete generation GO:0007292 74 0.061
regulation of cell adhesion GO:0030155 154 0.061
neurotransmitter transport GO:0006836 76 0.060
regulation of neurotransmitter levels GO:0001505 87 0.059
heterocycle catabolic process GO:0046700 280 0.059
Mouse Rat
regulation of neuron death GO:1901214 134 0.059
cyclic purine nucleotide metabolic process GO:0052652 43 0.059
granulocyte migration GO:0097530 43 0.059
Mouse
protein processing GO:0016485 163 0.059
membrane depolarization GO:0051899 64 0.059
positive regulation of growth GO:0045927 104 0.059
learning or memory GO:0007611 148 0.058
negative regulation of phosphorylation GO:0042326 166 0.058
Mouse
regulation of organelle organization GO:0033043 289 0.058
axonal fasciculation GO:0007413 15 0.058
regulation of protein serine threonine kinase activity GO:0071900 157 0.058
transmission of nerve impulse GO:0019226 76 0.057
activation of mapk activity involved in innate immune response GO:0035419 2 0.057
cellular ion homeostasis GO:0006873 165 0.057
Mouse
positive regulation of thymocyte migration GO:2000412 2 0.057
telencephalon cell migration GO:0022029 55 0.057
peptide transport GO:0015833 133 0.057
leukocyte differentiation GO:0002521 342 0.057
neuron neuron synaptic transmission GO:0007270 69 0.056
negative regulation of cell proliferation GO:0008285 296 0.056
anatomical structure maturation GO:0071695 49 0.056
blood vessel morphogenesis GO:0048514 285 0.056
regulation of blood circulation GO:1903522 93 0.055
Mouse
negative regulation of nervous system development GO:0051961 156 0.055
nuclear division GO:0000280 158 0.055
t cell proliferation GO:0042098 120 0.055
positive regulation of cytoskeleton organization GO:0051495 49 0.055
anion transport GO:0006820 177 0.054
hematopoietic progenitor cell differentiation GO:0002244 143 0.054
microtubule based process GO:0007017 236 0.053
negative regulation of cell migration GO:0030336 59 0.053
detection of stimulus GO:0051606 84 0.052
positive regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000309 1 0.052
cytoplasmic transport GO:0016482 234 0.050
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
regulation of eosinophil migration GO:2000416 2 0.050
myeloid cell activation involved in immune response GO:0002275 34 0.050
negative regulation of transferase activity GO:0051348 85 0.049
synaptic vesicle transport GO:0048489 57 0.049
lipid catabolic process GO:0016042 69 0.049
neuron apoptotic process GO:0051402 142 0.049
regulation of secretion by cell GO:1903530 249 0.048
neuromuscular process controlling balance GO:0050885 59 0.048
oocyte differentiation GO:0009994 35 0.048
multi multicellular organism process GO:0044706 109 0.048
schwann cell differentiation GO:0014037 26 0.047
purine containing compound biosynthetic process GO:0072522 70 0.047
regulation of actin filament based process GO:0032970 99 0.047
Mouse
peripheral nervous system development GO:0007422 53 0.046
regulation of map kinase activity GO:0043405 120 0.046
positive regulation of eosinophil migration GO:2000418 2 0.046
amino acid transport GO:0006865 61 0.046
amide transport GO:0042886 138 0.045
conditioned taste aversion GO:0001661 4 0.045
peptidyl tyrosine phosphorylation GO:0018108 143 0.045
single organismal cell cell adhesion GO:0016337 131 0.045
skin development GO:0043588 220 0.045
positive regulation of programmed cell death GO:0043068 218 0.044
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.044
positive regulation of organelle organization GO:0010638 128 0.044
cell activation involved in immune response GO:0002263 126 0.044
adult behavior GO:0030534 135 0.044
bone resorption GO:0045453 38 0.044
positive regulation of protein kinase activity GO:0045860 144 0.044
regulation of cytokine production GO:0001817 266 0.044
nucleotide biosynthetic process GO:0009165 78 0.044
carboxylic acid transport GO:0046942 100 0.043
heart process GO:0003015 94 0.043
Mouse
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.043
action potential GO:0001508 78 0.043
clathrin coat assembly GO:0048268 2 0.043
behavioral response to nutrient GO:0051780 1 0.042
actin filament polymerization GO:0030041 44 0.042
clathrin mediated endocytosis GO:0072583 7 0.042
g protein coupled receptor internalization GO:0002031 3 0.042
negative regulation of immune system process GO:0002683 209 0.041
protein localization to plasma membrane GO:0072659 57 0.041
dopamine secretion GO:0014046 9 0.040
regulation of ral gtpase activity GO:0032315 4 0.040
acetylcholine secretion neurotransmission GO:0014055 2 0.040
purine ribonucleotide biosynthetic process GO:0009152 59 0.040
tissue homeostasis GO:0001894 115 0.040
regulation of cell growth GO:0001558 91 0.040
cellular response to lipid GO:0071396 145 0.040
Mouse
histone modification GO:0016570 159 0.040
positive regulation of cell adhesion GO:0045785 80 0.039
sensory organ morphogenesis GO:0090596 242 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.039
regulation of multi organism process GO:0043900 111 0.039
divalent inorganic cation homeostasis GO:0072507 138 0.039
Mouse
synaptic vesicle localization GO:0097479 59 0.039
negative regulation of kinase activity GO:0033673 81 0.038
regulation of peptide transport GO:0090087 91 0.038
activation of immune response GO:0002253 138 0.038
regulation of postsynaptic membrane potential GO:0060078 48 0.037
regulation of asymmetric cell division GO:0009786 4 0.037
synapse organization GO:0050808 125 0.037
regulation of system process GO:0044057 200 0.037
Mouse
leukocyte chemotaxis GO:0030595 69 0.037
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.037
positive regulation of t cell differentiation GO:0045582 52 0.037
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.036
negative regulation of synapse assembly GO:0051964 3 0.036
epithelial cell migration GO:0010631 63 0.036
organic acid transport GO:0015849 101 0.036
regulation of neurotransmitter secretion GO:0046928 29 0.036
meiotic nuclear division GO:0007126 115 0.036
regulation of cellular ketone metabolic process GO:0010565 66 0.035
neuron death GO:0070997 154 0.035
cell recognition GO:0008037 83 0.035
cell type specific apoptotic process GO:0097285 268 0.035
regulation of synaptic plasticity GO:0048167 87 0.035
cellular protein complex assembly GO:0043623 116 0.035
forebrain cell migration GO:0021885 58 0.035
positive regulation of rac gtpase activity GO:0032855 14 0.035
regulation of metal ion transport GO:0010959 106 0.035
Mouse
organic anion transport GO:0015711 137 0.034
regulation of thymocyte migration GO:2000410 2 0.034
positive regulation of actin filament polymerization GO:0030838 26 0.034
regulation of actin cytoskeleton organization GO:0032956 84 0.034
regulation of axon extension GO:0030516 43 0.034
regulation of t cell activation GO:0050863 170 0.034
protein catabolic process GO:0030163 221 0.034
response to light stimulus GO:0009416 135 0.034
hemostasis GO:0007599 78 0.034
cyclic nucleotide metabolic process GO:0009187 59 0.034
Mouse Rat
peptidyl amino acid modification GO:0018193 336 0.034
Mouse
cytokine production GO:0001816 319 0.034
fibronectin dependent thymocyte migration GO:0072681 1 0.034
rap protein signal transduction GO:0032486 3 0.034
hypothalamus cell differentiation GO:0021979 8 0.033
associative learning GO:0008306 61 0.033
detection of external stimulus GO:0009581 61 0.033
multi organism behavior GO:0051705 62 0.033
organic hydroxy compound biosynthetic process GO:1901617 77 0.033
sperm motility GO:0030317 47 0.033
homeostasis of number of cells GO:0048872 210 0.032
Mouse
regulation of feeding behavior GO:0060259 3 0.032
extracellular matrix dependent thymocyte migration GO:0072680 1 0.032
positive regulation of homeostatic process GO:0032846 64 0.032
prevention of polyspermy GO:0060468 4 0.032
regulation of extent of cell growth GO:0061387 52 0.032
leukocyte activation involved in immune response GO:0002366 126 0.032
camp biosynthetic process GO:0006171 31 0.032
peptidyl tyrosine modification GO:0018212 145 0.031
t cell differentiation GO:0030217 174 0.031
negative regulation of mapk cascade GO:0043409 65 0.031
stem cell proliferation GO:0072089 117 0.031
positive regulation of apoptotic process GO:0043065 217 0.031
sensory perception GO:0007600 245 0.031
Mouse
phospholipid metabolic process GO:0006644 87 0.031
regulation of proteolysis GO:0030162 164 0.031
oogenesis GO:0048477 56 0.031
neuroblast division GO:0055057 10 0.031
positive regulation of leukocyte differentiation GO:1902107 86 0.031
regulation of cell division GO:0051302 76 0.030
peptide secretion GO:0002790 114 0.030
vesicle organization GO:0016050 60 0.030
meiotic cell cycle GO:0051321 122 0.030
central nervous system neuron development GO:0021954 67 0.030
negative regulation of cell projection organization GO:0031345 56 0.030
negative regulation of growth GO:0045926 99 0.030
learning GO:0007612 98 0.030
regulation of reproductive process GO:2000241 66 0.030
neural tube formation GO:0001841 108 0.029
muscle contraction GO:0006936 101 0.029
Mouse
toxin transport GO:1901998 38 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.029
leukocyte homeostasis GO:0001776 79 0.029
Mouse
retina development in camera type eye GO:0060041 119 0.029
calcium ion transmembrane transport GO:0070588 85 0.029
Mouse
positive regulation of endocytosis GO:0045807 42 0.029
peptide hormone secretion GO:0030072 109 0.029
regulation of actin filament length GO:0030832 45 0.029
regulation of response to wounding GO:1903034 189 0.029
acetylcholine transport GO:0015870 2 0.029
oocyte construction GO:0007308 2 0.029
protein polymerization GO:0051258 57 0.028
organelle fission GO:0048285 170 0.028
eosinophil migration GO:0072677 3 0.028
skeletal system development GO:0001501 356 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
muscle system process GO:0003012 141 0.028
Mouse
regulation of body fluid levels GO:0050878 162 0.028
alpha beta t cell differentiation GO:0046632 69 0.028
alcohol metabolic process GO:0006066 116 0.028
purine nucleotide biosynthetic process GO:0006164 65 0.028
engulfment of apoptotic cell GO:0043652 3 0.028
regulation of muscle system process GO:0090257 80 0.027
Mouse
potassium ion transport GO:0006813 52 0.027
b cell activation GO:0042113 161 0.027
regulation of erk1 and erk2 cascade GO:0070372 71 0.027
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.027
regulation of dopamine secretion GO:0014059 9 0.027
endomembrane system organization GO:0010256 147 0.027
response to oxidative stress GO:0006979 123 0.027
detection of abiotic stimulus GO:0009582 60 0.026
small molecule catabolic process GO:0044282 71 0.026
regulation of amine transport GO:0051952 21 0.026
leukocyte degranulation GO:0043299 27 0.026
positive regulation of t cell activation GO:0050870 101 0.026
response to extracellular stimulus GO:0009991 127 0.026
carbohydrate homeostasis GO:0033500 128 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.026
mitotic cell cycle GO:0000278 195 0.026
protein maturation GO:0051604 176 0.026
negative regulation of axon extension GO:0030517 19 0.026
negative regulation of serotonin secretion GO:0014063 2 0.026
regulation of fibronectin dependent thymocyte migration GO:2000413 1 0.026
molting cycle GO:0042303 90 0.026
peptidyl serine phosphorylation GO:0018105 74 0.026
Mouse
establishment of synaptic vesicle localization GO:0097480 57 0.026
regulation of endocytosis GO:0030100 69 0.025
activation of ras gtpase activity GO:0032856 11 0.025
regulation of catecholamine secretion GO:0050433 12 0.025
long term synaptic potentiation GO:0060291 25 0.025
positive regulation of striated muscle contraction GO:0045989 3 0.025
glial cell differentiation GO:0010001 131 0.025
regulation of angiogenesis GO:0045765 81 0.025
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.025
positive regulation of transferase activity GO:0051347 167 0.025
negative regulation of organelle organization GO:0010639 90 0.025
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.025
bone development GO:0060348 120 0.025
positive regulation of protein transport GO:0051222 93 0.025
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.024
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.024
lipid modification GO:0030258 65 0.024
negative regulation of cell activation GO:0050866 111 0.024
eye photoreceptor cell differentiation GO:0001754 41 0.024
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.024
cranial nerve development GO:0021545 41 0.024
digestive tract morphogenesis GO:0048546 147 0.024
intracellular protein transport GO:0006886 204 0.024
interleukin 12 production GO:0032615 32 0.024
defecation GO:0030421 1 0.024
smooth muscle contraction GO:0006939 44 0.024
Mouse
metal ion homeostasis GO:0055065 189 0.024
Mouse
regulation of nucleotide biosynthetic process GO:0030808 34 0.024
stem cell development GO:0048864 219 0.024
blood coagulation GO:0007596 76 0.024
cell matrix adhesion GO:0007160 68 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.023
stem cell differentiation GO:0048863 268 0.023
divalent metal ion transport GO:0070838 172 0.023
Mouse
glycerophospholipid metabolic process GO:0006650 71 0.023
protein localization to organelle GO:0033365 185 0.023
response to transforming growth factor beta GO:0071559 88 0.023
regulation of muscle contraction GO:0006937 49 0.023
Mouse
actin filament bundle assembly GO:0051017 40 0.023
reproductive behavior GO:0019098 32 0.023
peptidyl serine modification GO:0018209 83 0.023
Mouse
response to oxygen levels GO:0070482 62 0.023
regulation of calcium ion dependent exocytosis GO:0017158 16 0.023
neural tube closure GO:0001843 90 0.023
nerve development GO:0021675 67 0.023
insulin secretion GO:0030073 89 0.023
mitotic cytokinesis GO:0000281 4 0.022
camera type eye development GO:0043010 266 0.022
regulation of circadian sleep wake cycle GO:0042749 3 0.022
response to temperature stimulus GO:0009266 55 0.022
compound eye development GO:0048749 1 0.022
developmental growth involved in morphogenesis GO:0060560 138 0.022

Pde1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.049