Mus musculus

72 known processes

Adam9

a disintegrin and metallopeptidase domain 9 (meltrin gamma)

(Aliases: Mltng,AU020942,MDC9,mKIAA0021)

Adam9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of apoptotic process GO:0043065 217 0.657
Mouse
activation of mapk activity involved in innate immune response GO:0035419 2 0.594
Mouse
cytokine production GO:0001816 319 0.583
Mouse
protein catabolic process GO:0030163 221 0.512
regulation of eosinophil migration GO:2000416 2 0.506
Mouse
organophosphate catabolic process GO:0046434 232 0.484
cellular response to growth factor stimulus GO:0071363 197 0.464
response to growth factor GO:0070848 198 0.445
positive regulation of cell death GO:0010942 224 0.444
Mouse
transmission of nerve impulse GO:0019226 76 0.430
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.429
Human Mouse
establishment of vesicle localization GO:0051650 81 0.414
positive regulation of cellular catabolic process GO:0031331 148 0.396
metal ion homeostasis GO:0055065 189 0.385
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.383
Mouse
prevention of polyspermy GO:0060468 4 0.377
Mouse
establishment of organelle localization GO:0051656 122 0.337
myelination GO:0042552 74 0.312
Mouse
blood vessel morphogenesis GO:0048514 285 0.305
Mouse
cytoplasmic transport GO:0016482 234 0.303
regulation of response to wounding GO:1903034 189 0.301
Mouse
positive regulation of cell migration GO:0030335 109 0.298
Human Mouse
regulation of multi organism process GO:0043900 111 0.294
Mouse
regulation of protein localization GO:0032880 231 0.292
Human
vesicle localization GO:0051648 86 0.274
response to endoplasmic reticulum stress GO:0034976 53 0.274
macromolecule catabolic process GO:0009057 281 0.266
positive regulation of cell motility GO:2000147 116 0.261
Human Mouse
cell adhesion GO:0007155 329 0.250
Human Mouse
regulation of organelle organization GO:0033043 289 0.249
single organismal cell cell adhesion GO:0016337 131 0.245
Human Mouse
regulation of cell migration GO:0030334 219 0.243
Human Mouse
regulation of mapk cascade GO:0043408 248 0.237
Human Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.229
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.227
regulation of thymocyte migration GO:2000410 2 0.219
Mouse
nucleotide catabolic process GO:0009166 217 0.218
response to organonitrogen compound GO:0010243 246 0.209
cation transport GO:0006812 399 0.206
intracellular protein transport GO:0006886 204 0.204
multicellular organismal signaling GO:0035637 91 0.198
Mouse
cellular ion homeostasis GO:0006873 165 0.197
ensheathment of neurons GO:0007272 76 0.193
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.191
cellular metal ion homeostasis GO:0006875 151 0.188
defense response to bacterium GO:0042742 119 0.177
membrane organization GO:0061024 245 0.176
lipid transport GO:0006869 98 0.172
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.168
Mouse
cellular chemical homeostasis GO:0055082 215 0.167
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.166
Human Mouse
nitrogen compound transport GO:0071705 271 0.165
positive regulation of proteolysis GO:0045862 85 0.158
positive regulation of protein modification process GO:0031401 299 0.158
Human Mouse
endomembrane system organization GO:0010256 147 0.156
small gtpase mediated signal transduction GO:0007264 97 0.154
regulation of secretion by cell GO:1903530 249 0.151
Human
regulation of cell activation GO:0050865 289 0.150
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.147
regulation of neuron apoptotic process GO:0043523 122 0.146
Mouse
neuronal action potential GO:0019228 54 0.145
Mouse
positive regulation of programmed cell death GO:0043068 218 0.143
Mouse
transmembrane transport GO:0055085 412 0.142
response to organic cyclic compound GO:0014070 198 0.139
single organism cell adhesion GO:0098602 156 0.138
Human Mouse
response to transforming growth factor beta GO:0071559 88 0.137
regulation of cell projection organization GO:0031344 206 0.136
regulation of membrane potential GO:0042391 192 0.136
Mouse
cation homeostasis GO:0055080 212 0.134
adaptive immune response GO:0002250 155 0.133
Mouse
action potential GO:0001508 78 0.133
Mouse
extracellular matrix dependent thymocyte migration GO:0072680 1 0.131
Mouse
cellular protein catabolic process GO:0044257 155 0.129
purine nucleoside metabolic process GO:0042278 241 0.129
cell junction organization GO:0034330 77 0.127
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.127
positive regulation of leukocyte apoptotic process GO:2000108 21 0.126
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.126
regulation of ion transport GO:0043269 215 0.125
cell recognition GO:0008037 83 0.124
Mouse
anion transport GO:0006820 177 0.122
regulation of neuron projection development GO:0010975 169 0.121
regulation of cytoskeleton organization GO:0051493 122 0.120
cellular homeostasis GO:0019725 240 0.119
regulation of cellular response to growth factor stimulus GO:0090287 82 0.118
Mouse
leukocyte homeostasis GO:0001776 79 0.116
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.116
homeostasis of number of cells GO:0048872 210 0.115
Mouse
regulation of neuron differentiation GO:0045664 281 0.113
positive regulation of defense response GO:0031349 124 0.112
Mouse
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.110
Mouse
leukocyte chemotaxis GO:0030595 69 0.110
Mouse
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.107
cellular calcium ion homeostasis GO:0006874 119 0.106
negative regulation of neuron apoptotic process GO:0043524 92 0.105
Mouse
lymphocyte differentiation GO:0030098 242 0.105
Mouse
myeloid cell apoptotic process GO:0033028 22 0.104
Mouse
cell growth GO:0016049 130 0.104
regulation of secretion GO:0051046 274 0.102
Human
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.102
Mouse
regulation of protein catabolic process GO:0042176 108 0.101
nucleoside metabolic process GO:0009116 246 0.097
axonogenesis GO:0007409 274 0.097
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.095
nucleoside phosphate metabolic process GO:0006753 338 0.095
glycoprotein catabolic process GO:0006516 5 0.094
guanosine containing compound metabolic process GO:1901068 144 0.094
regulation of leukocyte apoptotic process GO:2000106 56 0.093
Mouse
angiogenesis GO:0001525 201 0.093
Mouse
ion transmembrane transport GO:0034220 361 0.093
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.092
regulation of inflammatory response GO:0050727 147 0.091
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.091
synaptic vesicle recycling GO:0036465 19 0.091
fatty acid derivative transport GO:1901571 14 0.090
response to osmotic stress GO:0006970 21 0.087
response to peptide hormone GO:0043434 127 0.085
t cell differentiation GO:0030217 174 0.083
Mouse
blood coagulation GO:0007596 76 0.083
regulation of exocytosis GO:0017157 61 0.082
neuron death GO:0070997 154 0.081
Mouse
defense response to other organism GO:0098542 197 0.081
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.080
regulation of innate immune response GO:0045088 91 0.079
Mouse
regulation of defense response GO:0031347 233 0.077
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.077
regulation of t cell activation GO:0050863 170 0.076
Mouse
ceramide biosynthetic process GO:0046513 20 0.074
regulation of intracellular transport GO:0032386 159 0.074
gtp catabolic process GO:0006184 143 0.074
negative regulation of cellular component organization GO:0051129 194 0.074
positive regulation of cell development GO:0010720 237 0.073
positive regulation of cytokine production GO:0001819 174 0.073
Mouse
purine nucleotide metabolic process GO:0006163 302 0.072
wound healing GO:0042060 157 0.071
thymocyte migration GO:0072679 2 0.071
Mouse
regulation of cell adhesion GO:0030155 154 0.070
Human Mouse
neutrophil degranulation GO:0043312 6 0.070
retrograde transport endosome to golgi GO:0042147 2 0.069
organic anion transport GO:0015711 137 0.069
ribonucleoside triphosphate metabolic process GO:0009199 220 0.068
nucleoside catabolic process GO:0009164 206 0.068
response to ph GO:0009268 14 0.068
regulation of actin filament based process GO:0032970 99 0.068
fibronectin dependent thymocyte migration GO:0072681 1 0.068
Mouse
positive regulation of response to wounding GO:1903036 66 0.068
Mouse
cellular amino acid metabolic process GO:0006520 103 0.067
calcium ion homeostasis GO:0055074 127 0.067
regulation of cellular catabolic process GO:0031329 242 0.066
regulation of t cell differentiation GO:0045580 83 0.065
Mouse
myelination in peripheral nervous system GO:0022011 19 0.065
Mouse
protein processing GO:0016485 163 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.064
rac protein signal transduction GO:0016601 13 0.063
divalent metal ion transport GO:0070838 172 0.063
digestive system development GO:0055123 200 0.063
sequestering of calcium ion GO:0051208 18 0.062
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.061
Human Mouse
cell type specific apoptotic process GO:0097285 268 0.061
Mouse
positive regulation of sequestering of triglyceride GO:0010890 4 0.061
organelle localization GO:0051640 179 0.061
regulation of cell motility GO:2000145 236 0.061
Human Mouse
organic acid transport GO:0015849 101 0.061
mapk cascade GO:0000165 281 0.060
Human Mouse
purine nucleoside catabolic process GO:0006152 205 0.060
ubiquitin dependent protein catabolic process GO:0006511 129 0.060
oxygen homeostasis GO:0032364 2 0.060
skin development GO:0043588 220 0.059
Human
immune response regulating signaling pathway GO:0002764 125 0.058
Mouse
synaptic transmission GO:0007268 329 0.058
regulation of homeostatic process GO:0032844 182 0.058
Mouse
cell cell adhesion GO:0098609 41 0.058
visual behavior GO:0007632 45 0.058
Mouse
cell substrate adhesion GO:0031589 130 0.058
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.058
neurotransmitter secretion GO:0007269 62 0.057
protein localization to membrane GO:0072657 108 0.057
regulation of synaptic plasticity GO:0048167 87 0.057
positive regulation of lymphocyte activation GO:0051251 140 0.056
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.056
peptide secretion GO:0002790 114 0.056
leukocyte differentiation GO:0002521 342 0.056
Mouse
peptidyl amino acid modification GO:0018193 336 0.055
coagulation GO:0050817 78 0.055
regulation of cytoplasmic transport GO:1903649 112 0.054
hormone secretion GO:0046879 128 0.054
ras protein signal transduction GO:0007265 77 0.054
sphingolipid biosynthetic process GO:0030148 26 0.053
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.053
regionalization GO:0003002 337 0.053
response to peptide GO:1901652 136 0.053
axon ensheathment GO:0008366 76 0.053
Mouse
heart morphogenesis GO:0003007 178 0.053
Mouse
neuron apoptotic process GO:0051402 142 0.052
Mouse
regulation of neuronal synaptic plasticity GO:0048168 30 0.052
regulation of lymphocyte activation GO:0051249 240 0.052
Mouse
aromatic compound catabolic process GO:0019439 286 0.052
regulation of leukocyte differentiation GO:1902105 159 0.052
Mouse
actin polymerization or depolymerization GO:0008154 54 0.051
t cell apoptotic process GO:0070231 39 0.050
Mouse
positive regulation of kinase activity GO:0033674 155 0.050
Human Mouse
regulation of cytokine production GO:0001817 266 0.049
Mouse
regulation of cellular component size GO:0032535 121 0.048
positive regulation of cell projection organization GO:0031346 95 0.048
calcium ion transport GO:0006816 159 0.048
regulation of proteolysis GO:0030162 164 0.048
protein localization to plasma membrane GO:0072659 57 0.048
regulation of metal ion transport GO:0010959 106 0.048
anatomical structure homeostasis GO:0060249 145 0.047
Mouse
visual learning GO:0008542 44 0.047
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.047
glycoprotein metabolic process GO:0009100 116 0.047
icosanoid secretion GO:0032309 12 0.047
cellular macromolecule catabolic process GO:0044265 206 0.047
multi organism behavior GO:0051705 62 0.047
leukocyte migration GO:0050900 124 0.047
Mouse
divalent inorganic cation transport GO:0072511 178 0.046
inflammatory response GO:0006954 244 0.046
Mouse
regulation of receptor activity GO:0010469 41 0.046
cellular protein complex assembly GO:0043623 116 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
regulation of protein kinase activity GO:0045859 232 0.045
Human Mouse
chemotaxis GO:0006935 247 0.045
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.044
response to insulin GO:0032868 100 0.044
positive regulation of map kinase activity GO:0043406 84 0.044
Human Mouse
actin filament organization GO:0007015 113 0.044
sequestering of metal ion GO:0051238 19 0.043
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
positive regulation of cell adhesion GO:0045785 80 0.043
Human Mouse
epithelial cell migration GO:0010631 63 0.042
Human
positive regulation of mapk cascade GO:0043410 170 0.042
Human Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.042
Mouse
regulation of cell growth GO:0001558 91 0.041
establishment of protein localization to organelle GO:0072594 118 0.041
multi multicellular organism process GO:0044706 109 0.041
cellular divalent inorganic cation homeostasis GO:0072503 127 0.041
regulation of anatomical structure size GO:0090066 178 0.041
glycoprotein biosynthetic process GO:0009101 89 0.041
activation of immune response GO:0002253 138 0.040
Mouse
positive regulation of inflammatory response GO:0050729 47 0.040
Mouse
actin cytoskeleton organization GO:0030036 220 0.040
cellular response to hormone stimulus GO:0032870 150 0.040
cellular response to organonitrogen compound GO:0071417 145 0.040
sperm egg recognition GO:0035036 37 0.040
Mouse
negative regulation of growth GO:0045926 99 0.040
calcium ion dependent exocytosis GO:0017156 35 0.039
nucleoside phosphate catabolic process GO:1901292 222 0.039
immune effector process GO:0002252 321 0.039
exocytosis GO:0006887 121 0.039
regulation of hydrolase activity GO:0051336 246 0.039
positive regulation of protein kinase b signaling GO:0051897 32 0.039
Mouse
metanephric ascending thin limb development GO:0072218 2 0.039
positive regulation of transferase activity GO:0051347 167 0.039
Human Mouse
tissue homeostasis GO:0001894 115 0.039
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.038
fertilization GO:0009566 127 0.038
Mouse
positive regulation of t cell differentiation GO:0045582 52 0.038
Mouse
long term synaptic potentiation GO:0060291 25 0.038
cellular lipid metabolic process GO:0044255 323 0.038
response to acid chemical GO:0001101 111 0.038
germ cell development GO:0007281 185 0.037
stem cell development GO:0048864 219 0.037
Mouse
negative regulation of neuron death GO:1901215 98 0.037
Mouse
cellular response to acidic ph GO:0071468 4 0.037
endocytosis GO:0006897 168 0.036
circulatory system process GO:0003013 197 0.036
regulation of actin cytoskeleton organization GO:0032956 84 0.036
interleukin 8 secretion GO:0072606 3 0.036
biomineral tissue development GO:0031214 64 0.035
positive regulation of hydrolase activity GO:0051345 148 0.035
innate immune response GO:0045087 157 0.035
Mouse
granulocyte migration GO:0097530 43 0.035
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.035
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.035
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.035
Mouse
stem cell differentiation GO:0048863 268 0.034
Mouse
amine metabolic process GO:0009308 45 0.034
regulation of neuron death GO:1901214 134 0.034
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.034
purine containing compound metabolic process GO:0072521 311 0.034
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.033
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.033
negative regulation of molecular function GO:0044092 258 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
membrane protein proteolysis GO:0033619 10 0.033
regulation of protein transport GO:0051223 163 0.032
Human
ribonucleoside metabolic process GO:0009119 245 0.032
rab protein signal transduction GO:0032482 1 0.032
negative regulation of multi organism process GO:0043901 68 0.032
Mouse
microtubule based process GO:0007017 236 0.032
hemostasis GO:0007599 78 0.032
ameboidal type cell migration GO:0001667 128 0.032
Human
regulation of nucleocytoplasmic transport GO:0046822 73 0.031
regulation of lymphocyte differentiation GO:0045619 107 0.031
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
mitotic cell cycle process GO:1903047 159 0.031
positive regulation of neuron projection development GO:0010976 79 0.031
positive regulation of lymphocyte differentiation GO:0045621 61 0.031
Mouse
cellular response to insulin stimulus GO:0032869 78 0.031
single fertilization GO:0007338 82 0.030
Mouse
positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 12 0.030
Mouse
l amino acid transport GO:0015807 32 0.030
protein targeting GO:0006605 143 0.030
cell adhesion mediated by integrin GO:0033627 18 0.030
Human
gland development GO:0048732 330 0.030
interleukin 8 production GO:0032637 4 0.030
carbohydrate transport GO:0008643 62 0.030
regulation of map kinase activity GO:0043405 120 0.029
Human Mouse
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.029
positive regulation of cell cycle g1 s phase transition GO:1902808 9 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
regulation of muscle contraction GO:0006937 49 0.029
regulation of purine nucleotide metabolic process GO:1900542 169 0.029
cell chemotaxis GO:0060326 81 0.029
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.028
cell activation involved in immune response GO:0002263 126 0.028
positive regulation of homeostatic process GO:0032846 64 0.028
Mouse
microtubule based movement GO:0007018 84 0.028
synaptic vesicle transport GO:0048489 57 0.028
positive regulation of protein kinase activity GO:0045860 144 0.028
Human Mouse
oocyte construction GO:0007308 2 0.028
positive regulation of cell activation GO:0050867 158 0.028
Mouse
calcium ion transport into cytosol GO:0060402 48 0.028
gastrulation GO:0007369 116 0.028
negative regulation of exocytosis GO:0045920 12 0.028
regulation of tissue remodeling GO:0034103 38 0.027
Mouse
organelle assembly GO:0070925 177 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
sodium ion transport GO:0006814 73 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.027
Mouse
positive regulation of secretion by cell GO:1903532 114 0.027
Human
negative regulation of secretion GO:0051048 61 0.027
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.027
small molecule biosynthetic process GO:0044283 132 0.027
establishment of synaptic vesicle localization GO:0097480 57 0.027
positive regulation of cell cycle GO:0045787 92 0.026
b cell differentiation GO:0030183 78 0.026
Mouse
positive regulation of lipid storage GO:0010884 10 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
stress activated mapk cascade GO:0051403 80 0.026
regulation of intracellular protein transport GO:0033157 82 0.026
apoptotic signaling pathway GO:0097190 306 0.026
t cell activation GO:0042110 289 0.025
Mouse
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.025
lipid localization GO:0010876 126 0.025
negative regulation of ion transport GO:0043271 28 0.025
regulation of t cell differentiation in thymus GO:0033081 24 0.025
Mouse
cellular amine metabolic process GO:0044106 44 0.025
protein kinase b signaling GO:0043491 74 0.025
Mouse
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.025
positive regulation of dna templated transcription elongation GO:0032786 2 0.025
membrane fusion GO:0061025 38 0.025
regulation of ossification GO:0030278 112 0.025
carboxylic acid transport GO:0046942 100 0.025
endoplasmic reticulum unfolded protein response GO:0030968 19 0.025
negative regulation of cell growth GO:0030308 44 0.025
establishment of protein localization to membrane GO:0090150 54 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
organophosphate ester transport GO:0015748 28 0.025
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.025
Mouse
nucleotide metabolic process GO:0009117 332 0.024
positive regulation of leukocyte differentiation GO:1902107 86 0.024
Mouse
positive regulation of nervous system development GO:0051962 221 0.024
regulation of transporter activity GO:0032409 57 0.024
mesenchyme development GO:0060485 152 0.024
Mouse
superoxide metabolic process GO:0006801 27 0.024
regulation of ion transmembrane transporter activity GO:0032412 54 0.024
myeloid cell homeostasis GO:0002262 114 0.024
Mouse
substrate adhesion dependent cell spreading GO:0034446 30 0.024
cellular response to starvation GO:0009267 57 0.024
synapse organization GO:0050808 125 0.024
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.024
synaptic vesicle localization GO:0097479 59 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
odontogenesis GO:0042476 78 0.023
purine containing compound catabolic process GO:0072523 213 0.023
mesenchymal cell differentiation GO:0048762 107 0.023
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.023
Mouse
peptide hormone secretion GO:0030072 109 0.023
sterol metabolic process GO:0016125 58 0.023
protein localization to nucleus GO:0034504 121 0.023
actin filament polymerization GO:0030041 44 0.023
cation transmembrane transport GO:0098655 266 0.023
protein localization to organelle GO:0033365 185 0.023
vacuole organization GO:0007033 38 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.023
respiratory tube development GO:0030323 167 0.022
regulation of reproductive process GO:2000241 66 0.022
Mouse
membrane protein ectodomain proteolysis GO:0006509 7 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
regeneration GO:0031099 38 0.022
protein import into nucleus GO:0006606 95 0.022
positive regulation of t cell activation GO:0050870 101 0.022
Mouse
insulin secretion GO:0030073 89 0.022
axon target recognition GO:0007412 4 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
muscle system process GO:0003012 141 0.021
schwann cell differentiation GO:0014037 26 0.021
Mouse
negative regulation of protein transport GO:0051224 46 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.021
response to steroid hormone GO:0048545 56 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
cell cell recognition GO:0009988 44 0.021
Mouse
gliogenesis GO:0042063 141 0.020
Mouse
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.020
peptide metabolic process GO:0006518 46 0.020
synaptic vesicle endocytosis GO:0048488 19 0.020
tissue regeneration GO:0042246 22 0.020
single organism nuclear import GO:1902593 95 0.020
regulation of protein stability GO:0031647 52 0.020
maintenance of location GO:0051235 89 0.020
locomotory behavior GO:0007626 195 0.020
Mouse
regulation of t cell apoptotic process GO:0070232 28 0.020
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.020
positive regulation of secretion GO:0051047 130 0.020
Human
protein localization to vacuole GO:0072665 4 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
regulation of protein kinase b signaling GO:0051896 56 0.020
Mouse
er nucleus signaling pathway GO:0006984 27 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.019
mesodermal cell migration GO:0008078 4 0.019
schwann cell development GO:0014044 22 0.019
Mouse
positive regulation of phagocytosis engulfment GO:0060100 3 0.019
digestive tract morphogenesis GO:0048546 147 0.019
g1 s transition of mitotic cell cycle GO:0000082 57 0.019
phospholipid transport GO:0015914 21 0.019
regulation of calcium ion dependent exocytosis GO:0017158 16 0.019
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.019
Mouse
regulation of interleukin 8 secretion GO:2000482 2 0.019
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.019
regulation of protein import into nucleus GO:0042306 52 0.019
positive regulation of organelle organization GO:0010638 128 0.019
heterocycle catabolic process GO:0046700 280 0.019
regulation of cell cycle GO:0051726 281 0.019
segmentation GO:0035282 93 0.019
myeloid leukocyte mediated immunity GO:0002444 42 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
regulation of biomineral tissue development GO:0070167 33 0.019
gonad development GO:0008406 141 0.019
leukocyte migration involved in inflammatory response GO:0002523 7 0.019
Mouse
response to radiation GO:0009314 165 0.019
Mouse
ribose phosphate metabolic process GO:0019693 291 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
cell cell junction organization GO:0045216 72 0.018
negative regulation of response to wounding GO:1903035 77 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
axon guidance GO:0007411 141 0.018
regulation of lymphocyte apoptotic process GO:0070228 41 0.018
Mouse
regulation of cell cycle g1 s phase transition GO:1902806 35 0.018
cerebellar cortex morphogenesis GO:0021696 32 0.018
regulation of cell substrate adhesion GO:0010810 73 0.018
pigmentation GO:0043473 71 0.018
cellular response to acid chemical GO:0071229 68 0.018
regulation of body fluid levels GO:0050878 162 0.018
smoothened signaling pathway GO:0007224 105 0.018
regulation of membrane lipid distribution GO:0097035 16 0.018
myosin filament assembly GO:0031034 2 0.018
digestive tract development GO:0048565 190 0.018
vesicle organization GO:0016050 60 0.018
phospholipid translocation GO:0045332 9 0.018
amide transport GO:0042886 138 0.018
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.018
Mouse
epithelial cell development GO:0002064 159 0.018
acute inflammatory response GO:0002526 41 0.018
Mouse
glycerolipid metabolic process GO:0046486 122 0.017
regulation of cellular response to stress GO:0080135 159 0.017
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
response to nutrient levels GO:0031667 109 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
nuclear import GO:0051170 95 0.017
neuron projection extension GO:1990138 64 0.017
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.017
peptide transport GO:0015833 133 0.017
response to monosaccharide GO:0034284 67 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
positive regulation of cell cycle process GO:0090068 61 0.017
lymphocyte homeostasis GO:0002260 64 0.017
long chain fatty acid metabolic process GO:0001676 26 0.017
learning GO:0007612 98 0.017
Mouse
membrane lipid biosynthetic process GO:0046467 32 0.016
rap protein signal transduction GO:0032486 3 0.016
regulation of synaptic vesicle exocytosis GO:2000300 11 0.016
vascular process in circulatory system GO:0003018 62 0.016
negative regulation of calcium ion transmembrane transport GO:1903170 1 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
lipid biosynthetic process GO:0008610 179 0.016

Adam9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.501
inherited metabolic disorder DOID:655 0 0.501
lysosomal storage disease DOID:3211 0 0.031
lipid storage disease DOID:9455 0 0.018