Mus musculus

72 known processes

Spag8

sperm associated antigen 8

(Aliases: MH-SPAG8)

Spag8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mapk cascade GO:0000165 281 0.071
regulation of protein kinase activity GO:0045859 232 0.061
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.058
negative regulation of cell proliferation GO:0008285 296 0.058
positive regulation of mapk cascade GO:0043410 170 0.053
actin cytoskeleton organization GO:0030036 220 0.052
positive regulation of protein modification process GO:0031401 299 0.050
regulation of protein serine threonine kinase activity GO:0071900 157 0.047
regulation of mapk cascade GO:0043408 248 0.047
positive regulation of protein phosphorylation GO:0001934 242 0.046
single organismal cell cell adhesion GO:0016337 131 0.046
fat cell differentiation GO:0045444 160 0.041
gland development GO:0048732 330 0.041
peptidyl amino acid modification GO:0018193 336 0.038
morphogenesis of a branching structure GO:0001763 203 0.038
cell junction assembly GO:0034329 52 0.036
regulation of map kinase activity GO:0043405 120 0.036
epithelial tube morphogenesis GO:0060562 303 0.035
cell substrate adhesion GO:0031589 130 0.033
cell cell junction organization GO:0045216 72 0.033
regulation of transferase activity GO:0051338 263 0.031
positive regulation of protein kinase activity GO:0045860 144 0.031
neural precursor cell proliferation GO:0061351 121 0.030
morphogenesis of embryonic epithelium GO:0016331 159 0.030
activation of immune response GO:0002253 138 0.029
cell junction organization GO:0034330 77 0.028
immune response activating signal transduction GO:0002757 116 0.028
liver development GO:0001889 66 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
negative regulation of hepatocyte proliferation GO:2000346 3 0.027
transmembrane transport GO:0055085 412 0.027
regulation of cell adhesion GO:0030155 154 0.027
antigen receptor mediated signaling pathway GO:0050851 64 0.026
morphogenesis of a branching epithelium GO:0061138 193 0.026
cilium assembly GO:0042384 81 0.026
ras protein signal transduction GO:0007265 77 0.026
cell adhesion GO:0007155 329 0.025
regulation of organelle organization GO:0033043 289 0.025
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.024
cell matrix adhesion GO:0007160 68 0.024
cilium morphogenesis GO:0060271 102 0.024
hepaticobiliary system development GO:0061008 67 0.023
negative regulation of fat cell differentiation GO:0045599 36 0.023
cell fate commitment GO:0045165 210 0.023
male gamete generation GO:0048232 285 0.022
positive regulation of cilium movement GO:0003353 1 0.022
microtubule based process GO:0007017 236 0.022
sensory perception GO:0007600 245 0.022
response to growth factor GO:0070848 198 0.021
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.021
apoptotic signaling pathway GO:0097190 306 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
regulation of cell projection organization GO:0031344 206 0.021
macromolecule catabolic process GO:0009057 281 0.021
regulation of kinase activity GO:0043549 249 0.021
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.021
negative regulation of immune system process GO:0002683 209 0.020
positive regulation of map kinase activity GO:0043406 84 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
cellular ketone metabolic process GO:0042180 84 0.020
immune response regulating signaling pathway GO:0002764 125 0.020
membrane organization GO:0061024 245 0.020
regulation of hydrolase activity GO:0051336 246 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
regulation of proteolysis GO:0030162 164 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
sperm motility GO:0030317 47 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
integrin mediated signaling pathway GO:0007229 27 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
regulation of neural precursor cell proliferation GO:2000177 70 0.019
positive regulation of cell death GO:0010942 224 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
sequestering of calcium ion GO:0051208 18 0.019
cellular protein complex assembly GO:0043623 116 0.018
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.018
nucleotide metabolic process GO:0009117 332 0.018
regulation of cellular component size GO:0032535 121 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
purine containing compound catabolic process GO:0072523 213 0.018
negative regulation of neural precursor cell proliferation GO:2000178 18 0.018
organelle assembly GO:0070925 177 0.018
glycerolipid metabolic process GO:0046486 122 0.017
cytoplasmic transport GO:0016482 234 0.017
cell adhesion mediated by integrin GO:0033627 18 0.017
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.017
purine containing compound metabolic process GO:0072521 311 0.017
skeletal system development GO:0001501 356 0.017
cell type specific apoptotic process GO:0097285 268 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
cation transmembrane transport GO:0098655 266 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
cation transport GO:0006812 399 0.016
ossification GO:0001503 216 0.016
activation of mapk activity GO:0000187 59 0.016
regulation of fat cell differentiation GO:0045598 81 0.016
regulation of cell motility GO:2000145 236 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
regulation of anatomical structure size GO:0090066 178 0.015
cellular amine metabolic process GO:0044106 44 0.015
rho protein signal transduction GO:0007266 32 0.015
positive regulation of transferase activity GO:0051347 167 0.015
organelle fission GO:0048285 170 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
protein localization to organelle GO:0033365 185 0.015
lymphocyte proliferation GO:0046651 164 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
organophosphate catabolic process GO:0046434 232 0.015
regulation of cell size GO:0008361 72 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
positive regulation of kinase activity GO:0033674 155 0.015
b cell receptor signaling pathway GO:0050853 20 0.015
positive regulation of nervous system development GO:0051962 221 0.015
amine metabolic process GO:0009308 45 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
regulation of cell adhesion mediated by integrin GO:0033628 13 0.015
meiotic cell cycle GO:0051321 122 0.014
lateral inhibition GO:0046331 1 0.014
positive regulation of cell development GO:0010720 237 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
leukocyte differentiation GO:0002521 342 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
male gonad development GO:0008584 88 0.014
cellular lipid metabolic process GO:0044255 323 0.014
meiotic nuclear division GO:0007126 115 0.014
nitrogen compound transport GO:0071705 271 0.014
response to organonitrogen compound GO:0010243 246 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
oocyte axis specification GO:0007309 2 0.014
negative regulation of molecular function GO:0044092 258 0.014
immune effector process GO:0002252 321 0.014
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.014
nucleotide catabolic process GO:0009166 217 0.014
regulation of cell migration GO:0030334 219 0.014
divalent inorganic cation transport GO:0072511 178 0.014
mesodermal cell migration GO:0008078 4 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
protein catabolic process GO:0030163 221 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
negative regulation of antigen receptor mediated signaling pathway GO:0050858 16 0.013
negative regulation of cell development GO:0010721 169 0.013
spermatogenesis GO:0007283 284 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
oxidation reduction process GO:0055114 342 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
nuclear division GO:0000280 158 0.013
regulation of intracellular transport GO:0032386 159 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
ion transmembrane transport GO:0034220 361 0.013
organonitrogen compound catabolic process GO:1901565 264 0.012
male sex differentiation GO:0046661 109 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
divalent metal ion transport GO:0070838 172 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
regulation of neuron differentiation GO:0045664 281 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
positive regulation of organelle organization GO:0010638 128 0.012
protein localization to membrane GO:0072657 108 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
nucleoside metabolic process GO:0009116 246 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
regulation of cell cycle GO:0051726 281 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
cell killing GO:0001906 67 0.012
intracellular protein transport GO:0006886 204 0.012
spermatid differentiation GO:0048515 115 0.012
intracellular mrna localization GO:0008298 4 0.012
regulation of cell cycle process GO:0010564 160 0.012
response to acid chemical GO:0001101 111 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
exocytosis GO:0006887 121 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
leukocyte proliferation GO:0070661 172 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
striated muscle tissue development GO:0014706 293 0.011
cellular homeostasis GO:0019725 240 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
homeostasis of number of cells GO:0048872 210 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
substrate adhesion dependent cell spreading GO:0034446 30 0.011
cell growth GO:0016049 130 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
urogenital system development GO:0001655 261 0.011
protein maturation GO:0051604 176 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
sensory perception of sound GO:0007605 97 0.011
aromatic compound catabolic process GO:0019439 286 0.011
protein polyglycylation GO:0018094 3 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
macromolecule methylation GO:0043414 120 0.010
t cell activation GO:0042110 289 0.010
regulation of neuron projection development GO:0010975 169 0.010
cellularization GO:0007349 1 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
wnt signaling pathway GO:0016055 188 0.010
nuclear transport GO:0051169 139 0.010
carbohydrate metabolic process GO:0005975 230 0.010
sequestering of metal ion GO:0051238 19 0.010
adherens junction assembly GO:0034333 22 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
regulation of peptidase activity GO:0052547 96 0.010
fertilization GO:0009566 127 0.010
calcium ion homeostasis GO:0055074 127 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
forebrain development GO:0030900 302 0.010
response to organic cyclic compound GO:0014070 198 0.010
dna metabolic process GO:0006259 303 0.010
muscle cell differentiation GO:0042692 261 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
protein ubiquitination GO:0016567 171 0.010

Spag8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.013
sensory system disease DOID:0050155 0 0.012
disease of metabolism DOID:0014667 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
inherited metabolic disorder DOID:655 0 0.010