Mus musculus

202 known processes

Nr1h2

nuclear receptor subfamily 1, group H, member 2

(Aliases: Unr,OR-1,LXRbeta,NER1,AI194859,UR,RIP15,LXRB,Unr2,LXR)

Nr1h2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.210
Human
cellular response to hormone stimulus GO:0032870 150 0.188
glycerolipid metabolic process GO:0046486 122 0.181
Human
nitrogen compound transport GO:0071705 271 0.154
negative regulation of molecular function GO:0044092 258 0.134
regulation of cellular amino acid metabolic process GO:0006521 5 0.117
cellular lipid metabolic process GO:0044255 323 0.116
negative regulation of protein metabolic process GO:0051248 282 0.115
regulation of cellular ketone metabolic process GO:0010565 66 0.115
Human
regulation of hydrolase activity GO:0051336 246 0.113
Human
cellular response to peptide GO:1901653 92 0.101
regulation of lipid metabolic process GO:0019216 118 0.092
Human
protein maturation GO:0051604 176 0.089
cellular amine metabolic process GO:0044106 44 0.088
negative regulation of cellular protein metabolic process GO:0032269 247 0.088
regulation of protein localization GO:0032880 231 0.085
regulation of hormone levels GO:0010817 211 0.084
cellular amino acid metabolic process GO:0006520 103 0.082
amide transport GO:0042886 138 0.079
innate immune response GO:0045087 157 0.078
endocytosis GO:0006897 168 0.078
Human
cellular response to cytokine stimulus GO:0071345 189 0.078
anion transport GO:0006820 177 0.078
microtubule based process GO:0007017 236 0.077
negative regulation of defense response GO:0031348 77 0.075
Mouse
amine metabolic process GO:0009308 45 0.074
regulation of intracellular transport GO:0032386 159 0.073
protein localization to membrane GO:0072657 108 0.072
response to molecule of bacterial origin GO:0002237 143 0.071
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.071
positive regulation of mapk cascade GO:0043410 170 0.070
monocarboxylic acid metabolic process GO:0032787 191 0.069
Human
mapk cascade GO:0000165 281 0.069
positive regulation of cell death GO:0010942 224 0.068
apoptotic signaling pathway GO:0097190 306 0.067
negative regulation of phosphorylation GO:0042326 166 0.066
response to organonitrogen compound GO:0010243 246 0.065
protein processing GO:0016485 163 0.065
regulation of homeostatic process GO:0032844 182 0.064
carbohydrate homeostasis GO:0033500 128 0.063
regulation of establishment of protein localization GO:0070201 181 0.060
membrane organization GO:0061024 245 0.060
cellular response to biotic stimulus GO:0071216 92 0.060
Mouse
lipid localization GO:0010876 126 0.060
protein ubiquitination GO:0016567 171 0.059
regulation of organelle organization GO:0033043 289 0.059
negative regulation of phosphate metabolic process GO:0045936 184 0.059
response to peptide GO:1901652 136 0.058
protein modification by small protein conjugation GO:0032446 187 0.056
positive regulation of cell development GO:0010720 237 0.055
positive regulation of protein modification process GO:0031401 299 0.053
intracellular protein transport GO:0006886 204 0.053
negative regulation of pancreatic juice secretion GO:0090188 3 0.052
Mouse
glucose homeostasis GO:0042593 128 0.052
plasma membrane organization GO:0007009 90 0.052
peptide transport GO:0015833 133 0.052
cellular response to peptide hormone stimulus GO:0071375 92 0.051
response to nutrient levels GO:0031667 109 0.051
lipid biosynthetic process GO:0008610 179 0.050
Human
macromolecule catabolic process GO:0009057 281 0.050
response to peptide hormone GO:0043434 127 0.050
purine nucleoside triphosphate catabolic process GO:0009146 203 0.049
organic anion transport GO:0015711 137 0.048
lipid homeostasis GO:0055088 63 0.048
i kappab kinase nf kappab signaling GO:0007249 85 0.048
regulation of vacuole organization GO:0044088 4 0.048
vacuole organization GO:0007033 38 0.047
cell adhesion GO:0007155 329 0.047
regulation of inflammatory response GO:0050727 147 0.047
Mouse
protein catabolic process GO:0030163 221 0.047
fatty acid metabolic process GO:0006631 121 0.047
Human
negative regulation of immune system process GO:0002683 209 0.047
Mouse
endomembrane system organization GO:0010256 147 0.047
multi organism behavior GO:0051705 62 0.046
Worm
protein localization to organelle GO:0033365 185 0.045
glycoprotein metabolic process GO:0009100 116 0.045
ras protein signal transduction GO:0007265 77 0.045
phospholipid metabolic process GO:0006644 87 0.045
regulation of cholesterol homeostasis GO:2000188 9 0.045
glycerolipid biosynthetic process GO:0045017 50 0.045
Human
cytoplasmic transport GO:0016482 234 0.045
regulation of apoptotic signaling pathway GO:2001233 197 0.044
cellular response to lipid GO:0071396 145 0.043
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.043
skeletal system morphogenesis GO:0048705 203 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.043
regulation of cell cycle GO:0051726 281 0.043
cellular response to salt stress GO:0071472 1 0.042
negative regulation of cellular component organization GO:0051129 194 0.042
Human
actin cytoskeleton organization GO:0030036 220 0.041
regulation of defense response GO:0031347 233 0.041
Mouse
regulation of mapk cascade GO:0043408 248 0.040
positive regulation of apoptotic process GO:0043065 217 0.040
positive regulation of programmed cell death GO:0043068 218 0.040
regulation of protein transport GO:0051223 163 0.040
wnt signaling pathway GO:0016055 188 0.040
regulation of proteolysis GO:0030162 164 0.039
cellular response to organonitrogen compound GO:0071417 145 0.039
regulation of multi organism process GO:0043900 111 0.038
phosphatidic acid biosynthetic process GO:0006654 2 0.038
posttranscriptional regulation of gene expression GO:0010608 155 0.037
locomotory behavior GO:0007626 195 0.037
germ cell development GO:0007281 185 0.037
cellular response to dna damage stimulus GO:0006974 207 0.037
regulation of cellular component biogenesis GO:0044087 181 0.036
regulation of autophagy GO:0010506 30 0.036
microtubule cytoskeleton organization GO:0000226 157 0.036
macroautophagy GO:0016236 21 0.036
maintenance of location GO:0051235 89 0.036
protein targeting GO:0006605 143 0.035
regulation of peptide transport GO:0090087 91 0.035
body morphogenesis GO:0010171 45 0.034
Worm
cellular protein catabolic process GO:0044257 155 0.034
cation homeostasis GO:0055080 212 0.034
skin development GO:0043588 220 0.033
multi multicellular organism process GO:0044706 109 0.033
Worm
dna metabolic process GO:0006259 303 0.033
cellular ion homeostasis GO:0006873 165 0.033
blood vessel morphogenesis GO:0048514 285 0.033
regulation of cellular catabolic process GO:0031329 242 0.032
positive regulation of growth GO:0045927 104 0.032
regulation of response to wounding GO:1903034 189 0.032
Mouse
carbohydrate metabolic process GO:0005975 230 0.032
regulation of peptide secretion GO:0002791 77 0.032
response to organic cyclic compound GO:0014070 198 0.032
positive regulation of apoptotic signaling pathway GO:2001235 95 0.032
cellularization GO:0007349 1 0.032
spermatogenesis GO:0007283 284 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
organelle assembly GO:0070925 177 0.032
regulation of reproductive process GO:2000241 66 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
urogenital system development GO:0001655 261 0.032
establishment of protein localization to membrane GO:0090150 54 0.032
nucleoside metabolic process GO:0009116 246 0.031
response to acid chemical GO:0001101 111 0.031
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.031
neural tube development GO:0021915 160 0.031
cellular response to molecule of bacterial origin GO:0071219 83 0.031
Mouse
muscle cell differentiation GO:0042692 261 0.030
heterocycle catabolic process GO:0046700 280 0.030
multicellular organism growth GO:0035264 161 0.030
cation transport GO:0006812 399 0.030
peptide secretion GO:0002790 114 0.030
negative regulation of nervous system development GO:0051961 156 0.030
peptidyl serine modification GO:0018209 83 0.030
insulin secretion GO:0030073 89 0.030
positive regulation of neuron differentiation GO:0045666 141 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.029
nuclear import GO:0051170 95 0.029
protein localization to nucleus GO:0034504 121 0.029
cellular chemical homeostasis GO:0055082 215 0.029
vesicle localization GO:0051648 86 0.029
cellular response to lipopolysaccharide GO:0071222 77 0.029
Mouse
divalent inorganic cation transport GO:0072511 178 0.029
ribonucleoside metabolic process GO:0009119 245 0.028
insulin receptor signaling pathway GO:0008286 49 0.028
sensory perception GO:0007600 245 0.028
regulation of cellular response to stress GO:0080135 159 0.028
morphogenesis of a polarized epithelium GO:0001738 37 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
immune response regulating signaling pathway GO:0002764 125 0.028
dna recombination GO:0006310 92 0.028
spermatid development GO:0007286 108 0.028
regulation of cell migration GO:0030334 219 0.028
regulation of endocytosis GO:0030100 69 0.028
Human
regulation of innate immune response GO:0045088 91 0.028
positive regulation of homeostatic process GO:0032846 64 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.027
negative regulation of homeostatic process GO:0032845 71 0.027
neuron death GO:0070997 154 0.027
actin filament organization GO:0007015 113 0.027
epidermis development GO:0008544 187 0.027
regulation of protein maturation GO:1903317 96 0.027
regulation of protein processing GO:0070613 96 0.027
negative regulation of mapk cascade GO:0043409 65 0.027
regulation of kinase activity GO:0043549 249 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
regulation of neuron differentiation GO:0045664 281 0.026
engulfment of apoptotic cell GO:0043652 3 0.026
regulation of cell adhesion GO:0030155 154 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
hormone secretion GO:0046879 128 0.026
regulation of ion transport GO:0043269 215 0.026
cellular response to starvation GO:0009267 57 0.026
positive regulation of innate immune response GO:0045089 80 0.026
translation GO:0006412 93 0.026
defense response to other organism GO:0098542 197 0.025
cellular metal ion homeostasis GO:0006875 151 0.025
glycerophospholipid metabolic process GO:0006650 71 0.025
modification dependent macromolecule catabolic process GO:0043632 133 0.025
peptide hormone secretion GO:0030072 109 0.025
regulation of cell activation GO:0050865 289 0.025
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.025
cognition GO:0050890 149 0.025
organic acid transport GO:0015849 101 0.025
regulation of feeding behavior GO:0060259 3 0.024
Worm
spermatid differentiation GO:0048515 115 0.024
regulation of intracellular protein transport GO:0033157 82 0.024
cellular homeostasis GO:0019725 240 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
regulation of body fluid levels GO:0050878 162 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
learning or memory GO:0007611 148 0.024
purine containing compound catabolic process GO:0072523 213 0.024
regulation of lymphocyte proliferation GO:0050670 117 0.024
single organism nuclear import GO:1902593 95 0.024
skeletal muscle organ development GO:0060538 163 0.024
t cell activation GO:0042110 289 0.023
blood circulation GO:0008015 195 0.023
regulation of protein kinase activity GO:0045859 232 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
positive regulation of cell activation GO:0050867 158 0.023
establishment of organelle localization GO:0051656 122 0.023
protein kinase b signaling GO:0043491 74 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
nuclear transport GO:0051169 139 0.023
calcium ion transport GO:0006816 159 0.023
metal ion homeostasis GO:0055065 189 0.023
phosphatidic acid metabolic process GO:0046473 2 0.023
regulation of cytoplasmic transport GO:1903649 112 0.023
establishment of protein localization to organelle GO:0072594 118 0.022
sterol homeostasis GO:0055092 45 0.022
organelle localization GO:0051640 179 0.022
negative regulation of protein modification process GO:0031400 163 0.022
necrotic cell death GO:0070265 30 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
striated muscle tissue development GO:0014706 293 0.022
response to extracellular stimulus GO:0009991 127 0.022
cell type specific apoptotic process GO:0097285 268 0.022
camera type eye development GO:0043010 266 0.022
ameboidal type cell migration GO:0001667 128 0.022
lipid transport GO:0006869 98 0.022
angiogenesis GO:0001525 201 0.022
tissue homeostasis GO:0001894 115 0.022
peptidyl amino acid modification GO:0018193 336 0.021
feeding behavior GO:0007631 62 0.021
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
regulation of peptide hormone secretion GO:0090276 75 0.021
extrinsic apoptotic signaling pathway GO:0097191 126 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
rho protein signal transduction GO:0007266 32 0.021
autophagy GO:0006914 45 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
immune response activating signal transduction GO:0002757 116 0.021
regulation of cell projection organization GO:0031344 206 0.021
muscle tissue development GO:0060537 308 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
phagocytosis GO:0006909 66 0.021
positive regulation of defense response GO:0031349 124 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
positive regulation of hydrolase activity GO:0051345 148 0.020
Human
t cell differentiation GO:0030217 174 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
histone modification GO:0016570 159 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
organic hydroxy compound transport GO:0015850 93 0.020
negative regulation of proteolysis GO:0045861 74 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
cellular response to insulin stimulus GO:0032869 78 0.020
regulation of transferase activity GO:0051338 263 0.020
response to growth factor GO:0070848 198 0.020
response to radiation GO:0009314 165 0.020
protein import into nucleus GO:0006606 95 0.020
appendage development GO:0048736 166 0.020
myeloid cell differentiation GO:0030099 233 0.019
neuron apoptotic process GO:0051402 142 0.019
sequestering of metal ion GO:0051238 19 0.019
telencephalon development GO:0021537 186 0.019
rab protein signal transduction GO:0032482 1 0.019
myosin filament organization GO:0031033 3 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
regulation of cytokine production GO:0001817 266 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
meiotic nuclear division GO:0007126 115 0.019
negative regulation of cell development GO:0010721 169 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
sequestering of calcium ion GO:0051208 18 0.019
forebrain development GO:0030900 302 0.019
positive regulation of intracellular transport GO:0032388 70 0.019
regulation of anatomical structure size GO:0090066 178 0.019
acid secretion GO:0046717 33 0.018
response to starvation GO:0042594 65 0.018
regulation of triglyceride biosynthetic process GO:0010866 10 0.018
Human
cell substrate adhesion GO:0031589 130 0.018
development of primary sexual characteristics GO:0045137 143 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
response to insulin GO:0032868 100 0.018
regulation of protein import into nucleus GO:0042306 52 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
anatomical structure homeostasis GO:0060249 145 0.018
lymphocyte differentiation GO:0030098 242 0.018
regulation of protein catabolic process GO:0042176 108 0.018
positive regulation of cellular component biogenesis GO:0044089 94 0.018
cellular response to glucose stimulus GO:0071333 45 0.018
retrograde transport endosome to golgi GO:0042147 2 0.018
monosaccharide transport GO:0015749 58 0.018
organelle fission GO:0048285 170 0.018
cerebral cortex development GO:0021987 86 0.017
nuclear division GO:0000280 158 0.017
transcription factor import into nucleus GO:0042991 26 0.017
peptidyl lysine modification GO:0018205 77 0.017
negative regulation of protein processing GO:0010955 79 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
regulation of lipoprotein lipase activity GO:0051004 4 0.017
Human
protein localization to plasma membrane GO:0072659 57 0.017
memory GO:0007613 58 0.017
regulation of protein sumoylation GO:0033233 4 0.017
mrna metabolic process GO:0016071 84 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
ear development GO:0043583 200 0.017
cellular response to nutrient levels GO:0031669 64 0.017
immunoglobulin production GO:0002377 73 0.017
steroid metabolic process GO:0008202 119 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
adult behavior GO:0030534 135 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
cellular response to extracellular stimulus GO:0031668 81 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
regulation of secretion by cell GO:1903530 249 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
mitochondrion organization GO:0007005 134 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
intracellular receptor signaling pathway GO:0030522 74 0.016
adiponectin activated signaling pathway GO:0033211 4 0.016
stem cell differentiation GO:0048863 268 0.016
neural precursor cell proliferation GO:0061351 121 0.016
cellular response to acid chemical GO:0071229 68 0.016
regulation of vasculature development GO:1901342 88 0.016
transmission of nerve impulse GO:0019226 76 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
response to lipopolysaccharide GO:0032496 128 0.016
Mouse
male gamete generation GO:0048232 285 0.016
aromatic compound catabolic process GO:0019439 286 0.016
bone development GO:0060348 120 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
ribonucleoprotein complex disassembly GO:0032988 3 0.016
cellular glucose homeostasis GO:0001678 52 0.016
synaptonemal complex organization GO:0070193 15 0.016
regulation of t cell activation GO:0050863 170 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
cytokine production GO:0001816 319 0.015
regulation of membrane potential GO:0042391 192 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.015
lung development GO:0030324 164 0.015
regulation of map kinase activity GO:0043405 120 0.015
respiratory system development GO:0060541 190 0.015
sensory organ morphogenesis GO:0090596 242 0.015
nucleoside catabolic process GO:0009164 206 0.015
membrane tubulation GO:0097320 4 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
dephosphorylation GO:0016311 129 0.015
response to light stimulus GO:0009416 135 0.015
ossification GO:0001503 216 0.015
leukocyte proliferation GO:0070661 172 0.015
negative regulation of response to wounding GO:1903035 77 0.015
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.015
regulation of actin filament based process GO:0032970 99 0.014
limb morphogenesis GO:0035108 149 0.014
adaptive immune response GO:0002250 155 0.014
adherens junction maintenance GO:0034334 1 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
regulation of protein targeting GO:1903533 61 0.014
immune effector process GO:0002252 321 0.014
cytosolic calcium ion transport GO:0060401 48 0.014
b cell activation GO:0042113 161 0.014
nucleotide metabolic process GO:0009117 332 0.014
regulation of cell motility GO:2000145 236 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
divalent metal ion transport GO:0070838 172 0.014
oxidation reduction process GO:0055114 342 0.014
rna processing GO:0006396 105 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.014
toxin transport GO:1901998 38 0.014
regionalization GO:0003002 337 0.014
positive regulation of protein transport GO:0051222 93 0.014
limb development GO:0060173 166 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
Human
negative regulation of organelle organization GO:0010639 90 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
body fluid secretion GO:0007589 53 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
glycerophospholipid biosynthetic process GO:0046474 32 0.014
positive regulation of proteolysis GO:0045862 85 0.014
cellular response to oxidative stress GO:0034599 76 0.014
cholesterol efflux GO:0033344 24 0.014
cell division GO:0051301 120 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
execution phase of apoptosis GO:0097194 19 0.014
response to decreased oxygen levels GO:0036293 59 0.013
regulation of secretion GO:0051046 274 0.013
regulation of lipid biosynthetic process GO:0046890 54 0.013
Human
carbohydrate derivative catabolic process GO:1901136 231 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
positive regulation of cytoskeleton organization GO:0051495 49 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
chondrocyte differentiation GO:0002062 72 0.013
regulation of metal ion transport GO:0010959 106 0.013
compound eye development GO:0048749 1 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
fatty acid biosynthetic process GO:0006633 41 0.013
Human
organ growth GO:0035265 117 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
neutral lipid metabolic process GO:0006638 57 0.013
Human
cell fate commitment GO:0045165 210 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
gtp metabolic process GO:0046039 144 0.013
cellular response to external stimulus GO:0071496 88 0.013
regulation of autophagic vacuole assembly GO:2000785 4 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
rhythmic process GO:0048511 174 0.013
small molecule biosynthetic process GO:0044283 132 0.013
Human
nucleotide catabolic process GO:0009166 217 0.013
regulation of lipase activity GO:0060191 15 0.013
Human
positive regulation of organelle organization GO:0010638 128 0.013
skeletal system development GO:0001501 356 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
positive regulation of cholesterol homeostasis GO:2000189 2 0.013
protein lipid complex subunit organization GO:0071825 12 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
negative regulation of transferase activity GO:0051348 85 0.013
gland development GO:0048732 330 0.013
programmed necrotic cell death GO:0097300 28 0.012
chromatin modification GO:0016568 187 0.012
synapsis GO:0007129 34 0.012
response to monosaccharide GO:0034284 67 0.012
developmental maturation GO:0021700 193 0.012
regulation of neuron projection development GO:0010975 169 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
positive regulation of lipid transport GO:0032370 22 0.012
protein import GO:0017038 101 0.012
cartilage development GO:0051216 140 0.012
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
asymmetric neuroblast division GO:0055059 1 0.012
regulation of peptidase activity GO:0052547 96 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
negative regulation of protein transport GO:0051224 46 0.012
Mouse
pallium development GO:0021543 120 0.012
b cell differentiation GO:0030183 78 0.012
negative regulation of cell cycle GO:0045786 123 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
chemotaxis GO:0006935 247 0.012
positive regulation of lipid biosynthetic process GO:0046889 18 0.012
Human
multicellular organismal aging GO:0010259 24 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
regulation of transcription factor import into nucleus GO:0042990 24 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
carbohydrate transport GO:0008643 62 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
positive regulation of ion transport GO:0043270 65 0.012
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.012
acylglycerol biosynthetic process GO:0046463 18 0.012
Human
regulation of lipid transport GO:0032368 36 0.012
release of sequestered calcium ion into cytosol GO:0051209 42 0.012
regulation of system process GO:0044057 200 0.012
cellular protein complex assembly GO:0043623 116 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
neuronal action potential GO:0019228 54 0.012
sperm individualization GO:0007291 1 0.012
response to temperature stimulus GO:0009266 55 0.012
positive regulation of immune effector process GO:0002699 107 0.012
embryonic placenta development GO:0001892 98 0.012
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
circulatory system process GO:0003013 197 0.011
negative regulation of kinase activity GO:0033673 81 0.011
macromolecule methylation GO:0043414 120 0.011
regulation of hormone secretion GO:0046883 88 0.011
activation of innate immune response GO:0002218 56 0.011
cellular response to gonadotropin stimulus GO:0071371 4 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
calcium ion homeostasis GO:0055074 127 0.011

Nr1h2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
immune system disease DOID:2914 0 0.043
hematopoietic system disease DOID:74 0 0.014
neuromuscular disease DOID:440 0 0.013
neuropathy DOID:870 0 0.013
disease of cellular proliferation DOID:14566 0 0.011