Mus musculus

86 known processes

Lypla1

lysophospholipase 1

(Aliases: Pla1a)

Lypla1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein targeting to peroxisome GO:0006625 4 0.465
nucleotide metabolic process GO:0009117 332 0.154
peroxisome organization GO:0007031 7 0.131
protein import into peroxisome matrix GO:0016558 3 0.125
organophosphate ester transport GO:0015748 28 0.124
protein targeting GO:0006605 143 0.120
c21 steroid hormone biosynthetic process GO:0006700 3 0.114
nucleoside phosphate metabolic process GO:0006753 338 0.113
organic anion transport GO:0015711 137 0.111
membrane organization GO:0061024 245 0.110
alcohol metabolic process GO:0006066 116 0.108
oxidation reduction process GO:0055114 342 0.106
cytoplasmic transport GO:0016482 234 0.101
establishment of protein localization to peroxisome GO:0072663 4 0.099
establishment of protein localization to organelle GO:0072594 118 0.093
ribonucleotide metabolic process GO:0009259 291 0.093
nucleoside metabolic process GO:0009116 246 0.092
peroxisomal transport GO:0043574 4 0.086
alcohol biosynthetic process GO:0046165 43 0.086
intra golgi vesicle mediated transport GO:0006891 1 0.085
cellular homeostasis GO:0019725 240 0.080
ribonucleoside metabolic process GO:0009119 245 0.073
defecation GO:0030421 1 0.069
organonitrogen compound biosynthetic process GO:1901566 192 0.067
glycosyl compound metabolic process GO:1901657 246 0.066
nucleobase containing small molecule metabolic process GO:0055086 352 0.066
organic hydroxy compound metabolic process GO:1901615 203 0.063
purine containing compound metabolic process GO:0072521 311 0.063
protein localization to membrane GO:0072657 108 0.062
fatty acid oxidation GO:0019395 28 0.061
lipid catabolic process GO:0016042 69 0.060
carbohydrate metabolic process GO:0005975 230 0.060
response to light stimulus GO:0009416 135 0.059
cellular lipid metabolic process GO:0044255 323 0.056
negative regulation of phosphate metabolic process GO:0045936 184 0.055
ribose phosphate metabolic process GO:0019693 291 0.055
circulatory system process GO:0003013 197 0.055
reactive oxygen species metabolic process GO:0072593 84 0.055
negative regulation of protein metabolic process GO:0051248 282 0.053
protein localization to peroxisome GO:0072662 4 0.052
gonad development GO:0008406 141 0.052
intracellular protein transport GO:0006886 204 0.050
purine nucleotide metabolic process GO:0006163 302 0.050
interleukin 8 secretion GO:0072606 3 0.049
ribonucleoside triphosphate metabolic process GO:0009199 220 0.048
nitrogen compound transport GO:0071705 271 0.047
regulation of cellular component biogenesis GO:0044087 181 0.044
cellular metal ion homeostasis GO:0006875 151 0.044
monocarboxylic acid catabolic process GO:0072329 27 0.044
myeloid cell differentiation GO:0030099 233 0.044
forebrain development GO:0030900 302 0.043
aromatic compound catabolic process GO:0019439 286 0.043
protein localization to plasma membrane GO:0072659 57 0.042
anion transport GO:0006820 177 0.042
plasma membrane organization GO:0007009 90 0.042
regulation of apoptotic signaling pathway GO:2001233 197 0.041
purine ribonucleotide metabolic process GO:0009150 290 0.041
nucleoside phosphate biosynthetic process GO:1901293 79 0.041
cation homeostasis GO:0055080 212 0.041
cellular protein complex assembly GO:0043623 116 0.040
small molecule biosynthetic process GO:0044283 132 0.039
regulation of intracellular transport GO:0032386 159 0.039
negative regulation of phosphorylation GO:0042326 166 0.038
lipid modification GO:0030258 65 0.038
multicellular organism growth GO:0035264 161 0.038
steroid metabolic process GO:0008202 119 0.037
purine ribonucleoside metabolic process GO:0046128 241 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
small molecule catabolic process GO:0044282 71 0.036
cellular ketone metabolic process GO:0042180 84 0.036
regulation of cellular catabolic process GO:0031329 242 0.036
negative regulation of molecular function GO:0044092 258 0.035
lipid biosynthetic process GO:0008610 179 0.034
endomembrane system organization GO:0010256 147 0.034
locomotory behavior GO:0007626 195 0.033
regulation of protein transport GO:0051223 163 0.033
cofactor transport GO:0051181 4 0.033
protein localization to organelle GO:0033365 185 0.033
golgi vesicle transport GO:0048193 30 0.032
regulation of cytoplasmic transport GO:1903649 112 0.032
progesterone biosynthetic process GO:0006701 1 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
sphingolipid metabolic process GO:0006665 45 0.031
response to radiation GO:0009314 165 0.030
cellular chemical homeostasis GO:0055082 215 0.030
endocytosis GO:0006897 168 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
regulation of protein stability GO:0031647 52 0.029
ubiquitin dependent protein catabolic process GO:0006511 129 0.029
organelle localization GO:0051640 179 0.029
vesicle organization GO:0016050 60 0.029
chromatin modification GO:0016568 187 0.028
establishment of vesicle localization GO:0051650 81 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
gtp catabolic process GO:0006184 143 0.028
regulation of hormone levels GO:0010817 211 0.028
regulation of membrane potential GO:0042391 192 0.027
negative regulation of immune system process GO:0002683 209 0.027
protein catabolic process GO:0030163 221 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
guanosine containing compound metabolic process GO:1901068 144 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.026
amide transport GO:0042886 138 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
chromatin organization GO:0006325 206 0.026
positive regulation of protein transport GO:0051222 93 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
membrane fusion GO:0061025 38 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
histone modification GO:0016570 159 0.025
morphogenesis of embryonic epithelium GO:0016331 159 0.025
regulation of cell projection organization GO:0031344 206 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
heterocycle catabolic process GO:0046700 280 0.024
purine containing compound catabolic process GO:0072523 213 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
organophosphate catabolic process GO:0046434 232 0.024
lipid transport GO:0006869 98 0.023
response to oxidative stress GO:0006979 123 0.023
progesterone metabolic process GO:0042448 4 0.023
cellular calcium ion homeostasis GO:0006874 119 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
regulation of lipid metabolic process GO:0019216 118 0.022
macromolecule catabolic process GO:0009057 281 0.022
retrograde transport endosome to golgi GO:0042147 2 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
polyol metabolic process GO:0019751 26 0.022
axonogenesis GO:0007409 274 0.022
multicellular organismal homeostasis GO:0048871 164 0.021
dna metabolic process GO:0006259 303 0.021
negative regulation of cell cycle GO:0045786 123 0.021
regulation of cell cycle GO:0051726 281 0.021
positive regulation of nucleotide metabolic process GO:0045981 114 0.021
regulation of purine nucleotide catabolic process GO:0033121 122 0.021
positive regulation of secretion GO:0051047 130 0.021
steroid biosynthetic process GO:0006694 47 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
regulation of neuron differentiation GO:0045664 281 0.021
maintenance of location GO:0051235 89 0.021
protein maturation GO:0051604 176 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
camera type eye development GO:0043010 266 0.020
leukocyte differentiation GO:0002521 342 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
striated muscle tissue development GO:0014706 293 0.020
negative regulation of protein modification process GO:0031400 163 0.020
hormone secretion GO:0046879 128 0.019
inositol phosphate catabolic process GO:0071545 4 0.019
cellular amino acid metabolic process GO:0006520 103 0.019
nuclear transport GO:0051169 139 0.019
male gamete generation GO:0048232 285 0.019
gtp metabolic process GO:0046039 144 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
rho protein signal transduction GO:0007266 32 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
positive regulation of protein modification process GO:0031401 299 0.018
spermatid development GO:0007286 108 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
regulation of cell cycle process GO:0010564 160 0.018
regulation of kinase activity GO:0043549 249 0.018
cellular ion homeostasis GO:0006873 165 0.017
neuron migration GO:0001764 122 0.017
synaptic transmission GO:0007268 329 0.017
regulation of autophagic vacuole assembly GO:2000785 4 0.017
multi organism behavior GO:0051705 62 0.017
hormone metabolic process GO:0042445 86 0.017
calcium ion homeostasis GO:0055074 127 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
multi multicellular organism process GO:0044706 109 0.017
purine nucleotide biosynthetic process GO:0006164 65 0.017
alpha amino acid biosynthetic process GO:1901607 15 0.017
regulation of mapk cascade GO:0043408 248 0.017
anatomical structure homeostasis GO:0060249 145 0.017
protein transmembrane transport GO:0071806 8 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
blood circulation GO:0008015 195 0.017
positive regulation of growth GO:0045927 104 0.017
regulation of transferase activity GO:0051338 263 0.016
fatty acid metabolic process GO:0006631 121 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
establishment of protein localization to membrane GO:0090150 54 0.016
positive regulation of cell development GO:0010720 237 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
protein secretion GO:0009306 111 0.016
dendrite development GO:0016358 115 0.016
regulation of protein kinase activity GO:0045859 232 0.016
regulation of system process GO:0044057 200 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
developmental maturation GO:0021700 193 0.016
regulation of organelle organization GO:0033043 289 0.016
lymphocyte proliferation GO:0046651 164 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
cholesterol homeostasis GO:0042632 44 0.016
positive regulation of intracellular transport GO:0032388 70 0.015
purine ribonucleotide biosynthetic process GO:0009152 59 0.015
apoptotic signaling pathway GO:0097190 306 0.015
male gonad development GO:0008584 88 0.015
metal ion homeostasis GO:0055065 189 0.015
dephosphorylation GO:0016311 129 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
germ cell development GO:0007281 185 0.015
nucleoside catabolic process GO:0009164 206 0.015
regulation of cell size GO:0008361 72 0.015
negative regulation of cell size GO:0045792 3 0.015
rhythmic process GO:0048511 174 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
sterol metabolic process GO:0016125 58 0.015
interleukin 8 production GO:0032637 4 0.015
regulation of interferon beta biosynthetic process GO:0045357 4 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
sensory perception GO:0007600 245 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
extracellular matrix organization GO:0030198 147 0.015
cytokinesis GO:0000910 17 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
positive regulation of cholesterol transport GO:0032376 9 0.014
regulation of protein oligomerization GO:0032459 4 0.014
synaptic vesicle localization GO:0097479 59 0.014
pigment biosynthetic process GO:0046148 26 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
amp metabolic process GO:0046033 4 0.014
atp metabolic process GO:0046034 75 0.014
regulation of secretion by cell GO:1903530 249 0.014
regulation of gtp catabolic process GO:0033124 113 0.014
positive regulation of neuron projection development GO:0010976 79 0.014
amine metabolic process GO:0009308 45 0.014
divalent inorganic cation transport GO:0072511 178 0.014
vesicle localization GO:0051648 86 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
ribose phosphate biosynthetic process GO:0046390 59 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
purine containing compound biosynthetic process GO:0072522 70 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
heart process GO:0003015 94 0.014
lipid oxidation GO:0034440 29 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
intracellular sterol transport GO:0032366 3 0.014
regulation of neuron projection development GO:0010975 169 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
regulation of protein targeting GO:1903533 61 0.013
regulation of protein localization GO:0032880 231 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
cell type specific apoptotic process GO:0097285 268 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
mitochondrial transport GO:0006839 36 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
regulation of sphingolipid biosynthetic process GO:0090153 1 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
gland development GO:0048732 330 0.013
regulation of lipid transport GO:0032368 36 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
positive regulation of tor signaling GO:0032008 3 0.013
glutamate biosynthetic process GO:0006537 2 0.013
alpha amino acid metabolic process GO:1901605 59 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
angiogenesis GO:0001525 201 0.013
regulation of steroid biosynthetic process GO:0050810 26 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
ribonucleotide biosynthetic process GO:0009260 59 0.013
nucleotide catabolic process GO:0009166 217 0.013
cation transport GO:0006812 399 0.013
copii coated vesicle budding GO:0090114 2 0.013
ossification GO:0001503 216 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
male sex differentiation GO:0046661 109 0.012
regulation of vacuole organization GO:0044088 4 0.012
protein folding GO:0006457 28 0.012
regionalization GO:0003002 337 0.012
regulation of cell motility GO:2000145 236 0.012
protein ubiquitination GO:0016567 171 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
protein homooligomerization GO:0051260 43 0.012
localization within membrane GO:0051668 4 0.012
mitotic cell cycle GO:0000278 195 0.012
myeloid cell homeostasis GO:0002262 114 0.012
cellular amine metabolic process GO:0044106 44 0.012
defense response to other organism GO:0098542 197 0.012
meiotic cell cycle GO:0051321 122 0.012
positive regulation of nervous system development GO:0051962 221 0.012
covalent chromatin modification GO:0016569 163 0.012
phospholipid metabolic process GO:0006644 87 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
phospholipid transport GO:0015914 21 0.012
regulation of steroid metabolic process GO:0019218 39 0.012
intracellular lipid transport GO:0032365 3 0.012
cargo loading into vesicle GO:0035459 3 0.011
lipid localization GO:0010876 126 0.011
spermatid differentiation GO:0048515 115 0.011
muscle cell differentiation GO:0042692 261 0.011
female sex differentiation GO:0046660 84 0.011
regulation of response to wounding GO:1903034 189 0.011
neuronal action potential GO:0019228 54 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
neural tube development GO:0021915 160 0.011
meiotic cytokinesis GO:0033206 5 0.011
extracellular structure organization GO:0043062 148 0.011
telencephalon development GO:0021537 186 0.011
cell maturation GO:0048469 127 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
protein import into nucleus GO:0006606 95 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
regulation of cell adhesion GO:0030155 154 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
muscle tissue development GO:0060537 308 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of anatomical structure size GO:0090066 178 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
regulation of lipid biosynthetic process GO:0046890 54 0.011
tube formation GO:0035148 140 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
bone morphogenesis GO:0060349 78 0.011
cholesterol metabolic process GO:0008203 56 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
ceramide metabolic process GO:0006672 31 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
glycerolipid metabolic process GO:0046486 122 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
oocyte construction GO:0007308 2 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
neural tube formation GO:0001841 108 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
regulation of proteolysis GO:0030162 164 0.011
development of primary sexual characteristics GO:0045137 143 0.011
negative regulation of intracellular transport GO:0032387 38 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
divalent metal ion transport GO:0070838 172 0.010
mapk cascade GO:0000165 281 0.010
establishment of synaptic vesicle localization GO:0097480 57 0.010
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
response to nutrient levels GO:0031667 109 0.010
epithelial cell development GO:0002064 159 0.010
establishment of protein localization to vacuole GO:0072666 4 0.010
regulation of cell migration GO:0030334 219 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
organic acid biosynthetic process GO:0016053 86 0.010

Lypla1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.063
inherited metabolic disorder DOID:655 0 0.063
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
central nervous system disease DOID:331 0 0.015
neurodegenerative disease DOID:1289 0 0.015
immune system disease DOID:2914 0 0.011
blood coagulation disease DOID:1247 0 0.011
hematopoietic system disease DOID:74 0 0.011