Mus musculus

121 known processes

Hmgcr

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

(Aliases: HMG-CoAR,MGC103269,Red)

Hmgcr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular alcohol biosynthetic process GO:0044108 3 0.607
lipid biosynthetic process GO:0008610 179 0.293
cellular alcohol metabolic process GO:0044107 3 0.212
sterol metabolic process GO:0016125 58 0.209
cellular lipid metabolic process GO:0044255 323 0.145
steroid metabolic process GO:0008202 119 0.128
alcohol metabolic process GO:0006066 116 0.122
organic hydroxy compound metabolic process GO:1901615 203 0.082
alcohol biosynthetic process GO:0046165 43 0.066
oxidation reduction process GO:0055114 342 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.061
cellular amine metabolic process GO:0044106 44 0.060
cellular amino acid metabolic process GO:0006520 103 0.058
small molecule biosynthetic process GO:0044283 132 0.057
cellular ketone metabolic process GO:0042180 84 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.055
transmembrane transport GO:0055085 412 0.053
cholesterol metabolic process GO:0008203 56 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
organic hydroxy compound biosynthetic process GO:1901617 77 0.047
negative regulation of cellular protein metabolic process GO:0032269 247 0.046
amine metabolic process GO:0009308 45 0.042
cholesterol biosynthetic process GO:0006695 15 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
ion transmembrane transport GO:0034220 361 0.038
synaptic transmission GO:0007268 329 0.037
male gamete generation GO:0048232 285 0.037
organonitrogen compound biosynthetic process GO:1901566 192 0.037
anion transport GO:0006820 177 0.037
cell adhesion GO:0007155 329 0.036
negative regulation of molecular function GO:0044092 258 0.036
negative regulation of protein metabolic process GO:0051248 282 0.034
regulation of transferase activity GO:0051338 263 0.034
sterol biosynthetic process GO:0016126 17 0.033
organelle assembly GO:0070925 177 0.032
cilium morphogenesis GO:0060271 102 0.031
positive regulation of protein modification process GO:0031401 299 0.031
protein catabolic process GO:0030163 221 0.031
nitrogen compound transport GO:0071705 271 0.030
regulation of organelle organization GO:0033043 289 0.030
regulation of secretion GO:0051046 274 0.029
cellular component assembly involved in morphogenesis GO:0010927 139 0.029
spermatogenesis GO:0007283 284 0.029
sensory perception GO:0007600 245 0.029
cellular chemical homeostasis GO:0055082 215 0.029
lipid transport GO:0006869 98 0.028
protein maturation GO:0051604 176 0.028
cellular homeostasis GO:0019725 240 0.028
monocarboxylic acid metabolic process GO:0032787 191 0.027
regulation of protein kinase activity GO:0045859 232 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
response to light stimulus GO:0009416 135 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
response to organonitrogen compound GO:0010243 246 0.026
skin development GO:0043588 220 0.026
peptidyl amino acid modification GO:0018193 336 0.026
microtubule based process GO:0007017 236 0.026
t cell activation GO:0042110 289 0.026
organic anion transport GO:0015711 137 0.026
macromolecule catabolic process GO:0009057 281 0.026
cation transmembrane transport GO:0098655 266 0.025
mapk cascade GO:0000165 281 0.025
response to radiation GO:0009314 165 0.025
response to peptide GO:1901652 136 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
steroid biosynthetic process GO:0006694 47 0.025
chemotaxis GO:0006935 247 0.025
regulation of membrane potential GO:0042391 192 0.024
organic acid transport GO:0015849 101 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
positive regulation of cell development GO:0010720 237 0.024
neuron death GO:0070997 154 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
aromatic compound catabolic process GO:0019439 286 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
actin cytoskeleton organization GO:0030036 220 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
cell type specific apoptotic process GO:0097285 268 0.023
cytoplasmic transport GO:0016482 234 0.023
apoptotic signaling pathway GO:0097190 306 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
cellular response to dna damage stimulus GO:0006974 207 0.022
response to extracellular stimulus GO:0009991 127 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
regulation of cell projection organization GO:0031344 206 0.022
nucleotide metabolic process GO:0009117 332 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
leukocyte differentiation GO:0002521 342 0.021
regulation of secretion by cell GO:1903530 249 0.021
digestive system development GO:0055123 200 0.021
heterocycle catabolic process GO:0046700 280 0.021
regulation of system process GO:0044057 200 0.021
protein processing GO:0016485 163 0.021
cation transport GO:0006812 399 0.021
epidermis development GO:0008544 187 0.021
mitochondrion organization GO:0007005 134 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
regulation of lipid metabolic process GO:0019216 118 0.020
regulation of cell adhesion GO:0030155 154 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
endocytosis GO:0006897 168 0.020
Worm
regulation of cell activation GO:0050865 289 0.020
sensory organ morphogenesis GO:0090596 242 0.020
axonogenesis GO:0007409 274 0.020
carbohydrate metabolic process GO:0005975 230 0.020
regulation of proteolysis GO:0030162 164 0.019
cellular biogenic amine metabolic process GO:0006576 28 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
glycerolipid metabolic process GO:0046486 122 0.019
positive regulation of transferase activity GO:0051347 167 0.019
regulation of ion transport GO:0043269 215 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
sterol transmembrane transport GO:0035382 2 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
gland development GO:0048732 330 0.019
lipid localization GO:0010876 126 0.019
Worm
posttranscriptional regulation of gene expression GO:0010608 155 0.019
ras protein signal transduction GO:0007265 77 0.019
Fly
regulation of kinase activity GO:0043549 249 0.019
regulation of hormone levels GO:0010817 211 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
compound eye development GO:0048749 1 0.018
circadian rhythm GO:0007623 114 0.018
nucleoside metabolic process GO:0009116 246 0.018
locomotory behavior GO:0007626 195 0.018
Fly
purine containing compound metabolic process GO:0072521 311 0.018
forebrain development GO:0030900 302 0.018
rhodopsin mediated signaling pathway GO:0016056 4 0.018
organophosphate catabolic process GO:0046434 232 0.018
regulation of neuron projection development GO:0010975 169 0.018
organelle fission GO:0048285 170 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
regulation of cellular response to stress GO:0080135 159 0.018
membrane organization GO:0061024 245 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
hormone secretion GO:0046879 128 0.018
dna metabolic process GO:0006259 303 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
epithelial cell development GO:0002064 159 0.018
camera type eye development GO:0043010 266 0.018
multicellular organism growth GO:0035264 161 0.018
cilium assembly GO:0042384 81 0.018
maintenance of location GO:0051235 89 0.017
Worm
skeletal system development GO:0001501 356 0.017
regulation of neuron differentiation GO:0045664 281 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of cell cycle GO:0051726 281 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
response to nutrient levels GO:0031667 109 0.017
regulation of hydrolase activity GO:0051336 246 0.017
multicellular organismal signaling GO:0035637 91 0.017
regulation of mapk cascade GO:0043408 248 0.017
regulation of homeostatic process GO:0032844 182 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
stem cell differentiation GO:0048863 268 0.017
sequestering of calcium ion GO:0051208 18 0.017
response to acid chemical GO:0001101 111 0.017
rhythmic process GO:0048511 174 0.017
translation GO:0006412 93 0.017
protein ubiquitination GO:0016567 171 0.017
carboxylic acid transport GO:0046942 100 0.017
regulation of neuron death GO:1901214 134 0.017
carbohydrate homeostasis GO:0033500 128 0.017
peptide transport GO:0015833 133 0.017
spermatid differentiation GO:0048515 115 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
positive regulation of organelle organization GO:0010638 128 0.017
glucose homeostasis GO:0042593 128 0.017
smoothened signaling pathway GO:0007224 105 0.017
cellular ion homeostasis GO:0006873 165 0.017
action potential GO:0001508 78 0.016
myeloid cell differentiation GO:0030099 233 0.016
homeostasis of number of cells GO:0048872 210 0.016
respiratory system development GO:0060541 190 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
innate immune response GO:0045087 157 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
kidney development GO:0001822 213 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
inflammatory response GO:0006954 244 0.016
germ cell development GO:0007281 185 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
positive regulation of nervous system development GO:0051962 221 0.016
lung development GO:0030324 164 0.016
response to peptide hormone GO:0043434 127 0.016
neuronal action potential GO:0019228 54 0.016
sphingolipid metabolic process GO:0006665 45 0.016
muscle cell differentiation GO:0042692 261 0.016
striated muscle tissue development GO:0014706 293 0.016
mitotic cell cycle process GO:1903047 159 0.016
urogenital system development GO:0001655 261 0.016
amide transport GO:0042886 138 0.015
neural tube development GO:0021915 160 0.015
mrna metabolic process GO:0016071 84 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
nuclear division GO:0000280 158 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
protein palmitoylation GO:0018345 14 0.015
chromatin organization GO:0006325 206 0.015
divalent inorganic cation transport GO:0072511 178 0.015
positive regulation of secretion GO:0051047 130 0.015
chromatin modification GO:0016568 187 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
response to insulin GO:0032868 100 0.015
ear development GO:0043583 200 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
peptide secretion GO:0002790 114 0.015
anion transmembrane transport GO:0098656 71 0.015
blood vessel morphogenesis GO:0048514 285 0.015
glycoprotein metabolic process GO:0009100 116 0.015
transmission of nerve impulse GO:0019226 76 0.015
positive regulation of cell death GO:0010942 224 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.015
respiratory tube development GO:0030323 167 0.014
male sex differentiation GO:0046661 109 0.014
membrane lipid metabolic process GO:0006643 53 0.014
leukocyte proliferation GO:0070661 172 0.014
rho protein signal transduction GO:0007266 32 0.014
fatty acid metabolic process GO:0006631 121 0.014
spermatid development GO:0007286 108 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
regulation of response to wounding GO:1903034 189 0.014
single organism cell adhesion GO:0098602 156 0.014
metal ion homeostasis GO:0055065 189 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
stem cell development GO:0048864 219 0.014
detection of abiotic stimulus GO:0009582 60 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of cell migration GO:0030334 219 0.014
purine containing compound catabolic process GO:0072523 213 0.014
cell substrate adhesion GO:0031589 130 0.014
wnt signaling pathway GO:0016055 188 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
cellular response to lipid GO:0071396 145 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of protein processing GO:0070613 96 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
lipoprotein metabolic process GO:0042157 43 0.014
oocyte construction GO:0007308 2 0.014
cytokine production GO:0001816 319 0.014
anatomical structure homeostasis GO:0060249 145 0.014
renal system development GO:0072001 225 0.014
regulation of cell motility GO:2000145 236 0.014
learning or memory GO:0007611 148 0.014
muscle tissue development GO:0060537 308 0.014
divalent metal ion transport GO:0070838 172 0.014
placenta development GO:0001890 140 0.014
telencephalon development GO:0021537 186 0.014
cellular protein catabolic process GO:0044257 155 0.014
lateral inhibition GO:0046331 1 0.014
muscle system process GO:0003012 141 0.014
developmental maturation GO:0021700 193 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
intracellular protein transport GO:0006886 204 0.013
regulation of anatomical structure size GO:0090066 178 0.013
negative regulation of protein modification process GO:0031400 163 0.013
cell growth GO:0016049 130 0.013
negative regulation of neuron death GO:1901215 98 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
neuron apoptotic process GO:0051402 142 0.013
negative regulation of protein processing GO:0010955 79 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
sequestering of metal ion GO:0051238 19 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of defense response GO:0031347 233 0.013
epithelial tube formation GO:0072175 130 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
macromolecule glycosylation GO:0043413 55 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
digestive tract morphogenesis GO:0048546 147 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
angiogenesis GO:0001525 201 0.013
response to organic cyclic compound GO:0014070 198 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
demethylation GO:0070988 23 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
cellular protein complex assembly GO:0043623 116 0.013
neural tube formation GO:0001841 108 0.013
lymphocyte proliferation GO:0046651 164 0.013
dephosphorylation GO:0016311 129 0.013
immune effector process GO:0002252 321 0.013
tissue homeostasis GO:0001894 115 0.013
digestive tract development GO:0048565 190 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
positive regulation of kinase activity GO:0033674 155 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
myosin filament assembly GO:0031034 2 0.013
endomembrane system organization GO:0010256 147 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
b cell activation GO:0042113 161 0.013
organelle localization GO:0051640 179 0.013
epithelial cell proliferation GO:0050673 174 0.012
mitotic cell cycle GO:0000278 195 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
regulation of protein localization GO:0032880 231 0.012
peptide hormone secretion GO:0030072 109 0.012
rna processing GO:0006396 105 0.012
cation homeostasis GO:0055080 212 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
fat cell differentiation GO:0045444 160 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
blood circulation GO:0008015 195 0.012
detection of stimulus GO:0051606 84 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
response to growth factor GO:0070848 198 0.012
response to oxidative stress GO:0006979 123 0.012
extracellular structure organization GO:0043062 148 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
leukocyte homeostasis GO:0001776 79 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
skeletal muscle organ development GO:0060538 163 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
Fly
regulation of vesicle mediated transport GO:0060627 139 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
lymphocyte differentiation GO:0030098 242 0.012
liver development GO:0001889 66 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
circulatory system process GO:0003013 197 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
regulation of body fluid levels GO:0050878 162 0.012
ossification GO:0001503 216 0.012
response to monosaccharide GO:0034284 67 0.012
cellular response to peptide GO:1901653 92 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
meiotic nuclear division GO:0007126 115 0.012
regionalization GO:0003002 337 0.012
regulation of intracellular transport GO:0032386 159 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
heart morphogenesis GO:0003007 178 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
dendrite development GO:0016358 115 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
regulation of peptidase activity GO:0052547 96 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
histone modification GO:0016570 159 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
myosin filament organization GO:0031033 3 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
negative regulation of nervous system development GO:0051961 156 0.011
sulfur compound metabolic process GO:0006790 100 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
positive regulation of cell activation GO:0050867 158 0.011
phospholipid metabolic process GO:0006644 87 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
regulation of hormone secretion GO:0046883 88 0.011
response to inorganic substance GO:0010035 96 0.011
amino acid transport GO:0006865 61 0.011
covalent chromatin modification GO:0016569 163 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
regulation of cytokine production GO:0001817 266 0.011
defense response to bacterium GO:0042742 119 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
cellular response to external stimulus GO:0071496 88 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of protein transport GO:0051223 163 0.011
cellular response to nutrient levels GO:0031669 64 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
regulation of translation GO:0006417 71 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
positive regulation of growth GO:0045927 104 0.011
dna repair GO:0006281 107 0.011
calcium ion homeostasis GO:0055074 127 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
cognition GO:0050890 149 0.011
negative regulation of protein maturation GO:1903318 79 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
methylation GO:0032259 134 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
ameboidal type cell migration GO:0001667 128 0.011
intracellular mrna localization GO:0008298 4 0.011
insulin secretion GO:0030073 89 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
positive regulation of cytokine production GO:0001819 174 0.011
cell activation involved in immune response GO:0002263 126 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
negative regulation of proteolysis GO:0045861 74 0.011
nuclear transport GO:0051169 139 0.011
carbohydrate transport GO:0008643 62 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
cell matrix adhesion GO:0007160 68 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
negative regulation of immune system process GO:0002683 209 0.011
establishment of blood nerve barrier GO:0008065 3 0.011
gliogenesis GO:0042063 141 0.011
asymmetric stem cell division GO:0098722 3 0.011
regulation of metal ion transport GO:0010959 106 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
Fly
meiotic cell cycle GO:0051321 122 0.011
tube formation GO:0035148 140 0.011
negative regulation of phosphorylation GO:0042326 166 0.010
negative regulation of organelle organization GO:0010639 90 0.010
organic acid biosynthetic process GO:0016053 86 0.010
cellularization GO:0007349 1 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.010
embryonic placenta development GO:0001892 98 0.010
negative regulation of cell development GO:0010721 169 0.010
macromolecule methylation GO:0043414 120 0.010
t cell proliferation GO:0042098 120 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
regulation of transmembrane transport GO:0034762 128 0.010
isoprenoid metabolic process GO:0006720 29 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
neuron projection guidance GO:0097485 141 0.010
positive regulation of neuron projection development GO:0010976 79 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
muscle contraction GO:0006936 101 0.010
neural precursor cell proliferation GO:0061351 121 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
sterol transport GO:0015918 38 0.010
glycerolipid biosynthetic process GO:0045017 50 0.010
calcium ion transport GO:0006816 159 0.010
limb development GO:0060173 166 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
protein glycosylation GO:0006486 55 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
protein targeting GO:0006605 143 0.010
wound healing GO:0042060 157 0.010
actin filament organization GO:0007015 113 0.010

Hmgcr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
disease of metabolism DOID:0014667 0 0.024
inherited metabolic disorder DOID:655 0 0.024
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.017
cancer DOID:162 0 0.017
central nervous system disease DOID:331 0 0.016
immune system disease DOID:2914 0 0.010