|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.998
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.994
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.988
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.986
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.973
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.962
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.955
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.930
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.927
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.927
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.910
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.905
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.896
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.892
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.889
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.881
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.872
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.868
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.864
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.858
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.857
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.851
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.848
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.833
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.817
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.814
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.787
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.781
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.777
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.767
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.767
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.757
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.756
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.747
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.744
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.712
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.707
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.705
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.697
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.684
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.664
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.656
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.651
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.633
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.628
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
4 |
0.625
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.616
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.615
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.610
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.610
|
|
|
|
icosanoid biosynthetic process
|
GO:0046456 |
15 |
0.608
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.605
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.594
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.594
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.592
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.576
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.575
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.574
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.558
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.553
|
|
|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.551
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.550
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.546
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.541
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.532
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.531
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.529
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.528
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.525
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.525
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.518
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.517
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.514
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.510
|
|
|
|
granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0042253 |
2 |
0.510
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.497
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.495
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.491
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.490
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.484
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.480
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.473
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045423 |
2 |
0.472
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.471
|
|
|
|
leukotriene biosynthetic process
|
GO:0019370 |
5 |
0.468
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.467
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.465
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.465
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.457
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.448
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.448
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.445
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.443
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032645 |
3 |
0.441
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.437
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.427
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.421
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.421
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.414
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.401
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.398
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.394
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.394
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.394
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.393
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.386
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.375
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.372
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.368
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.367
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.365
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.362
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.354
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.353
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.352
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.347
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.343
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.341
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.340
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.335
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.334
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.333
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.331
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.327
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.325
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.324
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.323
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.321
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.318
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
6 |
0.318
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.314
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.314
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.314
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.311
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.307
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.307
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.303
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.300
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.300
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.298
|
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.296
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.295
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.294
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.294
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.293
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.292
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.292
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.291
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.290
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.287
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.284
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.283
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.280
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.279
|
Mouse |
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.276
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.274
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.274
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.273
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.272
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.269
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.268
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.267
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.266
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.266
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.263
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.258
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.258
|
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
7 |
0.257
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.253
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.250
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.247
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.246
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
13 |
0.245
|
|
|
|
positive regulation of bone remodeling
|
GO:0046852 |
13 |
0.244
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.244
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.238
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.236
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.235
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.233
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.233
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.231
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.230
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.228
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.226
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.226
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.224
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.224
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.222
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.221
|
|
|
|
positive regulation of type ii hypersensitivity
|
GO:0002894 |
4 |
0.220
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.220
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.220
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.220
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.219
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.219
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.216
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.214
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.214
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.214
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.212
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
9 |
0.212
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.212
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.209
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.207
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.206
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.204
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.202
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.201
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.201
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.199
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.195
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.194
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.193
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.193
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.192
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.191
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.187
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.186
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.184
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.184
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.183
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.183
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.182
|
|
|
|
negative regulation of antigen receptor mediated signaling pathway
|
GO:0050858 |
16 |
0.182
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.180
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.175
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.173
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.173
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.170
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.170
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.169
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.167
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.166
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.166
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.164
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.164
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.163
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.163
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
31 |
0.161
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.161
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.160
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.160
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.158
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.158
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.158
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.156
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.154
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.154
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.153
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.153
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.149
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.148
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.148
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.147
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.146
|
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.146
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.145
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.145
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.144
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.144
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.143
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.142
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.142
|
|
|
|
b 1a b cell differentiation
|
GO:0002337 |
2 |
0.142
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.142
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.141
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.141
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.141
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.139
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.139
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.139
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.139
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.138
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.137
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.137
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.137
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.137
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.137
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.137
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.136
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.136
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.135
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.135
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.134
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
18 |
0.133
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.133
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.131
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.131
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.131
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.130
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.130
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.129
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.129
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.129
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.128
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.126
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.126
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.126
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.125
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.124
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.123
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.123
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.122
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.121
|
|
|
|
positive regulation of cd24 biosynthetic process
|
GO:2000560 |
1 |
0.120
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.120
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032725 |
3 |
0.120
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.119
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.119
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.118
|
|
|
|
complement receptor mediated signaling pathway
|
GO:0002430 |
1 |
0.118
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.117
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.117
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.117
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.116
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.115
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.115
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.113
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.113
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.113
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.113
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.113
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.112
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.112
|
|
|
|
negative regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002924 |
3 |
0.111
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.111
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.110
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.110
|
|
|
|
interleukin 3 production
|
GO:0032632 |
3 |
0.109
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.109
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.109
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.108
|
|
|
|
cd24 biosynthetic process
|
GO:0035724 |
1 |
0.108
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.108
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.107
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.107
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.106
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.106
|
|
|
|
filtration diaphragm assembly
|
GO:0036058 |
1 |
0.105
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.105
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.105
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.104
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.104
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.104
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.103
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.103
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.102
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.101
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.101
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.099
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.099
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.098
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.097
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.097
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.097
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.096
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.096
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
45 |
0.095
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.094
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.094
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.093
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.093
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.092
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.092
|
|
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.092
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.091
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.091
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.091
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.090
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.089
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.089
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.089
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.087
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.087
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.086
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.086
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.086
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.085
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.085
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.084
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.084
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.084
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.084
|
|
|
|
positive regulation of oligodendrocyte differentiation
|
GO:0048714 |
9 |
0.083
|
|
|
|
granulocyte macrophage colony stimulating factor production
|
GO:0032604 |
3 |
0.083
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.082
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.081
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.081
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.081
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.080
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.080
|
|
|
|
regulation of cd24 biosynthetic process
|
GO:2000559 |
1 |
0.080
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.080
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.079
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.079
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.078
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.078
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.078
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.077
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.077
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.077
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.077
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.076
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.076
|
|
|
|
b 1 b cell differentiation
|
GO:0001923 |
3 |
0.076
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.076
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.075
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.075
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.075
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
1 |
0.075
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.075
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.075
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.074
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.074
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.074
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.074
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.074
|
|
|
|
negative regulation of notch signaling pathway
|
GO:0045746 |
14 |
0.074
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.073
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.072
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.072
|
Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.071
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.071
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.071
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.071
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
12 |
0.070
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.070
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.070
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.070
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.070
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.069
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.069
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.068
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.068
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.067
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
6 |
0.067
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.067
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.067
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.067
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.067
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.066
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.066
|
|
|
|
b cell proliferation involved in immune response
|
GO:0002322 |
5 |
0.066
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.066
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.065
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.065
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.065
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.065
|
|
|
|
serotonin secretion
|
GO:0001820 |
8 |
0.065
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.064
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.064
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.064
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.064
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.064
|
|
|
|
regulation of type iia hypersensitivity
|
GO:0001796 |
4 |
0.063
|
|
|
|
positive regulation of interferon gamma biosynthetic process
|
GO:0045078 |
4 |
0.063
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.062
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.062
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.062
|
|
|
|
leukotriene metabolic process
|
GO:0006691 |
7 |
0.062
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.062
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.062
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.061
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.061
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.061
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.061
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.061
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.061
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.061
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.061
|
|
|
|
regulation of bone resorption
|
GO:0045124 |
24 |
0.061
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.060
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.060
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.060
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.060
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.060
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.060
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.060
|
|
|
|
response to platelet derived growth factor
|
GO:0036119 |
6 |
0.060
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.059
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.059
|
Mouse |
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.059
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.059
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.059
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.059
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.058
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.058
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.058
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.058
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.058
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.058
|
|
