Mus musculus

0 known processes

Ugt1a1

UDP glucuronosyltransferase 1 family, polypeptide A1

(Aliases: UGT1A01,Gnt1,Udpgt-1a,UDPGT 1-1,UgtBr1)

Ugt1a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.159
cellular lipid metabolic process GO:0044255 323 0.141
cellular amino acid metabolic process GO:0006520 103 0.081
monocarboxylic acid metabolic process GO:0032787 191 0.073
cation transport GO:0006812 399 0.071
organic hydroxy compound metabolic process GO:1901615 203 0.066
transmembrane transport GO:0055085 412 0.063
lipid biosynthetic process GO:0008610 179 0.060
ion transmembrane transport GO:0034220 361 0.057
cellular ketone metabolic process GO:0042180 84 0.054
fatty acid metabolic process GO:0006631 121 0.054
amine metabolic process GO:0009308 45 0.050
organic cyclic compound catabolic process GO:1901361 295 0.049
xenobiotic catabolic process GO:0042178 1 0.048
cofactor metabolic process GO:0051186 80 0.046
cellular amine metabolic process GO:0044106 44 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.044
response to organonitrogen compound GO:0010243 246 0.040
alcohol metabolic process GO:0006066 116 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
small molecule biosynthetic process GO:0044283 132 0.038
anion transport GO:0006820 177 0.038
glutathione metabolic process GO:0006749 16 0.037
aromatic compound catabolic process GO:0019439 286 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
steroid metabolic process GO:0008202 119 0.036
nitrogen compound transport GO:0071705 271 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
cellular modified amino acid metabolic process GO:0006575 63 0.034
carbohydrate metabolic process GO:0005975 230 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
response to acid chemical GO:0001101 111 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
nucleotide metabolic process GO:0009117 332 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
small molecule catabolic process GO:0044282 71 0.033
purine containing compound metabolic process GO:0072521 311 0.032
organic anion transport GO:0015711 137 0.031
cation transmembrane transport GO:0098655 266 0.031
response to organic cyclic compound GO:0014070 198 0.031
reactive nitrogen species metabolic process GO:2001057 0 0.030
cellular homeostasis GO:0019725 240 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
heterocycle catabolic process GO:0046700 280 0.030
sulfur compound metabolic process GO:0006790 100 0.030
cytokine production GO:0001816 319 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
regulation of hormone levels GO:0010817 211 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
defense response to bacterium GO:0042742 119 0.029
response to inorganic substance GO:0010035 96 0.027
isoprenoid metabolic process GO:0006720 29 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
glycerolipid metabolic process GO:0046486 122 0.025
cellular lipid catabolic process GO:0044242 52 0.025
defense response to other organism GO:0098542 197 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
negative regulation of molecular function GO:0044092 258 0.025
peptide metabolic process GO:0006518 46 0.025
glycosyl compound metabolic process GO:1901657 246 0.024
regulation of cytokine production GO:0001817 266 0.024
regulation of reactive oxygen species metabolic process GO:2000377 40 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
response to lipopolysaccharide GO:0032496 128 0.024
cellular chemical homeostasis GO:0055082 215 0.024
innate immune response GO:0045087 157 0.024
membrane organization GO:0061024 245 0.024
inorganic cation transmembrane transport GO:0098662 207 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
leukocyte differentiation GO:0002521 342 0.023
immune effector process GO:0002252 321 0.023
regulation of secretion GO:0051046 274 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
divalent inorganic cation transport GO:0072511 178 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
divalent metal ion transport GO:0070838 172 0.022
carboxylic acid biosynthetic process GO:0046394 86 0.022
cellular response to lipid GO:0071396 145 0.022
cytoplasmic transport GO:0016482 234 0.022
sensory perception GO:0007600 245 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
male gamete generation GO:0048232 285 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
carbohydrate homeostasis GO:0033500 128 0.021
organic acid biosynthetic process GO:0016053 86 0.021
nucleoside metabolic process GO:0009116 246 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.021
positive regulation of protein modification process GO:0031401 299 0.020
gland development GO:0048732 330 0.020
cell adhesion GO:0007155 329 0.020
regulation of defense response GO:0031347 233 0.020
peptidyl amino acid modification GO:0018193 336 0.020
t cell activation GO:0042110 289 0.020
macromolecule catabolic process GO:0009057 281 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
nucleoside catabolic process GO:0009164 206 0.020
spermatogenesis GO:0007283 284 0.020
cation homeostasis GO:0055080 212 0.019
lipid transport GO:0006869 98 0.019
lipid catabolic process GO:0016042 69 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
organic acid catabolic process GO:0016054 51 0.019
apoptotic signaling pathway GO:0097190 306 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
cellular alcohol biosynthetic process GO:0044108 3 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
nadph regeneration GO:0006740 2 0.019
cellular ion homeostasis GO:0006873 165 0.018
regulation of transferase activity GO:0051338 263 0.018
icosanoid metabolic process GO:0006690 33 0.018
mapk cascade GO:0000165 281 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
regulation of organelle organization GO:0033043 289 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
carboxylic acid transport GO:0046942 100 0.018
lipid localization GO:0010876 126 0.018
regulation of secretion by cell GO:1903530 249 0.018
positive regulation of cell death GO:0010942 224 0.018
organelle fission GO:0048285 170 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
positive regulation of immune effector process GO:0002699 107 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.017
calcitriol biosynthetic process from calciol GO:0036378 3 0.017
hormone metabolic process GO:0042445 86 0.017
muscle cell differentiation GO:0042692 261 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
regulation of hydrolase activity GO:0051336 246 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
response to extracellular stimulus GO:0009991 127 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
regulation of system process GO:0044057 200 0.017
metal ion homeostasis GO:0055065 189 0.017
organophosphate catabolic process GO:0046434 232 0.017
maintenance of location GO:0051235 89 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
purine containing compound catabolic process GO:0072523 213 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
regulation of membrane potential GO:0042391 192 0.017
skeletal system development GO:0001501 356 0.017
cell type specific apoptotic process GO:0097285 268 0.017
endocytosis GO:0006897 168 0.017
regulation of mapk cascade GO:0043408 248 0.017
regulation of ion transport GO:0043269 215 0.017
blood circulation GO:0008015 195 0.016
regulation of kinase activity GO:0043549 249 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
organic acid transport GO:0015849 101 0.016
protein maturation GO:0051604 176 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.016
angiogenesis GO:0001525 201 0.016
polyamine catabolic process GO:0006598 2 0.016
striated muscle tissue development GO:0014706 293 0.016
myeloid cell differentiation GO:0030099 233 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
retinoid metabolic process GO:0001523 24 0.016
leukocyte mediated immunity GO:0002443 174 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
regulation of cell activation GO:0050865 289 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
fat soluble vitamin biosynthetic process GO:0042362 4 0.016
inflammatory response GO:0006954 244 0.016
glucose homeostasis GO:0042593 128 0.016
negative regulation of immune system process GO:0002683 209 0.016
respiratory tube development GO:0030323 167 0.016
response to metal ion GO:0010038 47 0.016
response to nutrient levels GO:0031667 109 0.016
regulation of homeostatic process GO:0032844 182 0.016
regulation of body fluid levels GO:0050878 162 0.016
homeostasis of number of cells GO:0048872 210 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.015
blood vessel morphogenesis GO:0048514 285 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
meiotic cell cycle GO:0051321 122 0.015
muscle tissue development GO:0060537 308 0.015
cholesterol metabolic process GO:0008203 56 0.015
renal system development GO:0072001 225 0.015
vitamin d3 metabolic process GO:0070640 3 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
rho protein signal transduction GO:0007266 32 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
terpenoid metabolic process GO:0006721 25 0.015
diterpenoid metabolic process GO:0016101 24 0.015
anatomical structure homeostasis GO:0060249 145 0.015
amide transport GO:0042886 138 0.015
regulation of anatomical structure size GO:0090066 178 0.015
response to drug GO:0042493 75 0.015
intracellular protein transport GO:0006886 204 0.015
regulation of cell motility GO:2000145 236 0.015
urogenital system development GO:0001655 261 0.015
regulation of response to wounding GO:1903034 189 0.015
cellular alcohol metabolic process GO:0044107 3 0.015
regulation of lymphocyte activation GO:0051249 240 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
meiotic nuclear division GO:0007126 115 0.014
multi multicellular organism process GO:0044706 109 0.014
lymphocyte proliferation GO:0046651 164 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
nuclear division GO:0000280 158 0.014
endomembrane system organization GO:0010256 147 0.014
lymphocyte differentiation GO:0030098 242 0.014
cell activation involved in immune response GO:0002263 126 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
regulation of cell cycle GO:0051726 281 0.014
nitrobenzene metabolic process GO:0018916 1 0.014
response to oxidative stress GO:0006979 123 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
regulation of cell migration GO:0030334 219 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
circulatory system process GO:0003013 197 0.014
calcium ion transport GO:0006816 159 0.014
monosaccharide metabolic process GO:0005996 106 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
regulation of binding GO:0051098 111 0.014
epithelial cell proliferation GO:0050673 174 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
protein catabolic process GO:0030163 221 0.013
chemotaxis GO:0006935 247 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
interleukin 8 production GO:0032637 4 0.013
wound healing GO:0042060 157 0.013
cellular response to acid chemical GO:0071229 68 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
fatty acid derivative metabolic process GO:1901568 33 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
ras protein signal transduction GO:0007265 77 0.013
glycoprotein metabolic process GO:0009100 116 0.013
leukocyte proliferation GO:0070661 172 0.013
tissue homeostasis GO:0001894 115 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
dna metabolic process GO:0006259 303 0.013
acetate metabolic process GO:0006083 1 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
nucleotide catabolic process GO:0009166 217 0.013
forebrain development GO:0030900 302 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of proteolysis GO:0030162 164 0.013
respiratory system development GO:0060541 190 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
regulation of interleukin 8 production GO:0032677 3 0.012
regulation of intracellular transport GO:0032386 159 0.012
kidney development GO:0001822 213 0.012
regulation of neuron differentiation GO:0045664 281 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
cellular amide metabolic process GO:0043603 58 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
transmission of nerve impulse GO:0019226 76 0.012
regulation of blood pressure GO:0008217 93 0.012
coenzyme metabolic process GO:0006732 52 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
response to amino acid GO:0043200 37 0.012
monocarboxylic acid catabolic process GO:0072329 27 0.012
hormone secretion GO:0046879 128 0.012
alpha beta t cell activation GO:0046631 91 0.012
regulation of cellular response to stress GO:0080135 159 0.012
regulation of protein transport GO:0051223 163 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
positive regulation of transferase activity GO:0051347 167 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of protein localization GO:0032880 231 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
camera type eye development GO:0043010 266 0.012
multicellular organismal signaling GO:0035637 91 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
response to steroid hormone GO:0048545 56 0.012
protein localization to organelle GO:0033365 185 0.012
positive regulation of defense response GO:0031349 124 0.012
placenta development GO:0001890 140 0.012
adaptive immune response GO:0002250 155 0.012
cellular response to nutrient levels GO:0031669 64 0.012
organic hydroxy compound transport GO:0015850 93 0.011
lung development GO:0030324 164 0.011
regulation of transmembrane transport GO:0034762 128 0.011
interleukin 8 secretion GO:0072606 3 0.011
cell recognition GO:0008037 83 0.011
actin cytoskeleton organization GO:0030036 220 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
axonogenesis GO:0007409 274 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
muscle system process GO:0003012 141 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
regulation of interleukin 8 secretion GO:2000482 2 0.011
nuclear transport GO:0051169 139 0.011
response to peptide GO:1901652 136 0.011
sensory organ morphogenesis GO:0090596 242 0.011
skin development GO:0043588 220 0.011
t cell differentiation GO:0030217 174 0.011
regulation of t cell activation GO:0050863 170 0.011
ossification GO:0001503 216 0.011
plasma membrane organization GO:0007009 90 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
synaptic transmission GO:0007268 329 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
organelle localization GO:0051640 179 0.011
protein localization to membrane GO:0072657 108 0.011
neuron death GO:0070997 154 0.011
peptide transport GO:0015833 133 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
heart morphogenesis GO:0003007 178 0.011
cellular response to cadmium ion GO:0071276 3 0.011
developmental maturation GO:0021700 193 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
response to starvation GO:0042594 65 0.011
response to oxygen levels GO:0070482 62 0.011
regulation of feeding behavior GO:0060259 3 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
stem cell differentiation GO:0048863 268 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
atp metabolic process GO:0046034 75 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
lateral inhibition GO:0046331 1 0.010
calcium ion homeostasis GO:0055074 127 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
cellular response to external stimulus GO:0071496 88 0.010
methylation GO:0032259 134 0.010
leukocyte migration GO:0050900 124 0.010
single organism cell adhesion GO:0098602 156 0.010
microtubule based process GO:0007017 236 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
sequestering of calcium ion GO:0051208 18 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
mrna metabolic process GO:0016071 84 0.010
muscle contraction GO:0006936 101 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
skeletal muscle organ development GO:0060538 163 0.010
gonad development GO:0008406 141 0.010
transition metal ion transport GO:0000041 38 0.010
unsaturated fatty acid metabolic process GO:0033559 31 0.010
ear development GO:0043583 200 0.010

Ugt1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.060
inherited metabolic disorder DOID:655 0 0.060
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.049
sensory system disease DOID:0050155 0 0.021
immune system disease DOID:2914 0 0.016
cardiovascular system disease DOID:1287 0 0.016
musculoskeletal system disease DOID:17 0 0.016
central nervous system disease DOID:331 0 0.014
connective tissue disease DOID:65 0 0.013
hematopoietic system disease DOID:74 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
retinal disease DOID:5679 0 0.011
retinal degeneration DOID:8466 0 0.011
bone disease DOID:0080001 0 0.011
bone development disease DOID:0080006 0 0.011