Mus musculus

15 known processes

Enam

enamelin

Enam biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myeloid cell differentiation GO:0030099 233 0.664
biomineral tissue development GO:0031214 64 0.162
ossification GO:0001503 216 0.141
negative regulation of protein metabolic process GO:0051248 282 0.132
lymphocyte mediated immunity GO:0002449 139 0.123
amine metabolic process GO:0009308 45 0.123
defense response to other organism GO:0098542 197 0.121
monocarboxylic acid metabolic process GO:0032787 191 0.119
response to organonitrogen compound GO:0010243 246 0.109
regulation of reactive oxygen species metabolic process GO:2000377 40 0.104
reactive oxygen species metabolic process GO:0072593 84 0.104
cellular amino acid metabolic process GO:0006520 103 0.100
ion transmembrane transport GO:0034220 361 0.094
leukocyte differentiation GO:0002521 342 0.088
protein maturation GO:0051604 176 0.088
regulation of cellular amino acid metabolic process GO:0006521 5 0.083
protein processing GO:0016485 163 0.082
forebrain development GO:0030900 302 0.080
cartilage development GO:0051216 140 0.078
regulation of cellular ketone metabolic process GO:0010565 66 0.077
lipid biosynthetic process GO:0008610 179 0.076
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.076
positive regulation of cell death GO:0010942 224 0.075
morphogenesis of a branching structure GO:0001763 203 0.073
oxidation reduction process GO:0055114 342 0.073
defense response to gram positive bacterium GO:0050830 50 0.072
fatty acid metabolic process GO:0006631 121 0.072
response to organic cyclic compound GO:0014070 198 0.071
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.070
positive regulation of apoptotic process GO:0043065 217 0.069
bone mineralization GO:0030282 54 0.069
cytokine production GO:0001816 319 0.066
regulation of lipid metabolic process GO:0019216 118 0.065
defense response to bacterium GO:0042742 119 0.065
fat cell differentiation GO:0045444 160 0.064
cellular response to organonitrogen compound GO:0071417 145 0.063
immune effector process GO:0002252 321 0.062
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.061
serotonin receptor signaling pathway GO:0007210 8 0.058
response to molecule of bacterial origin GO:0002237 143 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
regulation of angiotensin levels in blood GO:0002002 4 0.056
negative regulation of growth GO:0045926 99 0.056
negative regulation of apoptotic signaling pathway GO:2001234 104 0.056
regulation of leukocyte mediated immunity GO:0002703 104 0.055
regulation of cell cycle GO:0051726 281 0.055
positive regulation of programmed cell death GO:0043068 218 0.055
response to drug GO:0042493 75 0.052
neuronal action potential GO:0019228 54 0.052
odontogenesis GO:0042476 78 0.052
cellular lipid metabolic process GO:0044255 323 0.051
cellular ketone metabolic process GO:0042180 84 0.049
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
nucleotide metabolic process GO:0009117 332 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.047
regulation of cell motility GO:2000145 236 0.046
small molecule biosynthetic process GO:0044283 132 0.046
transmembrane transport GO:0055085 412 0.046
leukocyte mediated immunity GO:0002443 174 0.045
cellular amine metabolic process GO:0044106 44 0.044
reactive oxygen species biosynthetic process GO:1903409 8 0.043
innate immune response GO:0045087 157 0.042
regulation of establishment of protein localization GO:0070201 181 0.042
blood vessel morphogenesis GO:0048514 285 0.042
cell killing GO:0001906 67 0.042
humoral immune response GO:0006959 57 0.041
regulation of hydrolase activity GO:0051336 246 0.041
negative regulation of molecular function GO:0044092 258 0.041
response to stilbenoid GO:0035634 22 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
carboxylic acid biosynthetic process GO:0046394 86 0.041
carbohydrate derivative biosynthetic process GO:1901137 183 0.040
negative regulation of endothelial cell migration GO:0010596 4 0.040
regulation of membrane potential GO:0042391 192 0.040
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.039
response to nutrient levels GO:0031667 109 0.039
positive regulation of immunological synapse formation GO:2000522 1 0.039
regulation of myeloid cell differentiation GO:0045637 96 0.038
bone development GO:0060348 120 0.038
regulation of hormone levels GO:0010817 211 0.037
anatomical structure homeostasis GO:0060249 145 0.037
receptor mediated endocytosis GO:0006898 51 0.037
response to lipopolysaccharide GO:0032496 128 0.037
striated muscle tissue development GO:0014706 293 0.036
endocrine process GO:0050886 39 0.036
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.036
regulation of blood pressure GO:0008217 93 0.036
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.035
glial cell differentiation GO:0010001 131 0.035
morphogenesis of a branching epithelium GO:0061138 193 0.035
epithelial tube morphogenesis GO:0060562 303 0.034
regulation of peptidase activity GO:0052547 96 0.034
camera type eye development GO:0043010 266 0.033
digestive system development GO:0055123 200 0.033
regulation of dendritic cell chemotaxis GO:2000508 1 0.033
regulation of secretion by cell GO:1903530 249 0.033
disruption of cells of other organism GO:0044364 13 0.033
positive regulation of steroid hormone secretion GO:2000833 2 0.033
regulation of defense response GO:0031347 233 0.033
dibenzo p dioxin metabolic process GO:0018894 1 0.033
regulation of erk1 and erk2 cascade GO:0070372 71 0.033
leukocyte mediated cytotoxicity GO:0001909 62 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.031
positive regulation of cytokine production GO:0001819 174 0.031
regulation of secretion GO:0051046 274 0.031
regulation of protein processing GO:0070613 96 0.031
sensory perception GO:0007600 245 0.031
organ growth GO:0035265 117 0.031
positive regulation of defense response GO:0031349 124 0.031
multicellular organismal signaling GO:0035637 91 0.031
regulation of epithelial cell proliferation GO:0050678 141 0.030
cation transport GO:0006812 399 0.030
epithelial cell proliferation GO:0050673 174 0.029
carbohydrate metabolic process GO:0005975 230 0.029
extracellular matrix organization GO:0030198 147 0.029
histamine induced gastric acid secretion GO:0001697 1 0.029
negative regulation of protein processing GO:0010955 79 0.028
hormone metabolic process GO:0042445 86 0.028
regulation of fat cell differentiation GO:0045598 81 0.028
urogenital system development GO:0001655 261 0.028
cellular carbohydrate metabolic process GO:0044262 119 0.028
response to inorganic substance GO:0010035 96 0.028
endocytosis GO:0006897 168 0.028
negative regulation of adenylate cyclase activity GO:0007194 1 0.028
regulation of wnt signaling pathway GO:0030111 123 0.027
single fertilization GO:0007338 82 0.027
homeostasis of number of cells GO:0048872 210 0.027
positive regulation of epithelial cell proliferation GO:0050679 68 0.027
response to extracellular stimulus GO:0009991 127 0.027
regulation of endocytosis GO:0030100 69 0.026
connective tissue development GO:0061448 179 0.026
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.026
digestive tract development GO:0048565 190 0.026
protein secretion GO:0009306 111 0.026
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.026
fertilization GO:0009566 127 0.025
g protein coupled receptor internalization GO:0002031 3 0.025
regulation of monocyte chemotaxis GO:0090025 3 0.025
regulation of lymphocyte activation GO:0051249 240 0.025
negative regulation of proteolysis GO:0045861 74 0.025
cellular response to amino acid stimulus GO:0071230 29 0.025
activation of membrane attack complex GO:0001905 4 0.025
action potential GO:0001508 78 0.025
ras protein signal transduction GO:0007265 77 0.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.025
negative regulation of cell migration GO:0030336 59 0.024
regulation of leukocyte differentiation GO:1902105 159 0.024
unsaturated fatty acid metabolic process GO:0033559 31 0.024
stem cell differentiation GO:0048863 268 0.024
regulation of angiotensin metabolic process GO:0060177 4 0.024
cardiac muscle tissue development GO:0048738 130 0.024
t helper 17 cell chemotaxis GO:0035705 1 0.024
nitrogen compound transport GO:0071705 271 0.023
cellular response to biotic stimulus GO:0071216 92 0.023
cell adhesion GO:0007155 329 0.023
cellular response to temperature stimulus GO:0071502 2 0.023
cellular response to starvation GO:0009267 57 0.023
organic hydroxy compound transport GO:0015850 93 0.023
cellular response to extracellular stimulus GO:0031668 81 0.023
cellular response to cadmium ion GO:0071276 3 0.023
regulation of protein secretion GO:0050708 82 0.023
divalent metal ion transport GO:0070838 172 0.023
regulation of cell division GO:0051302 76 0.022
hematopoietic stem cell migration GO:0035701 1 0.022
positive regulation of endocytosis GO:0045807 42 0.022
regulation of ion transport GO:0043269 215 0.022
positive regulation of glycolytic process GO:0045821 4 0.022
regulation of body fluid levels GO:0050878 162 0.022
transmission of nerve impulse GO:0019226 76 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.022
immune complex clearance GO:0002434 2 0.021
fatty acid derivative metabolic process GO:1901568 33 0.021
skeletal system development GO:0001501 356 0.021
negative regulation of immune system process GO:0002683 209 0.021
amino acid transmembrane transport GO:0003333 37 0.021
apoptotic signaling pathway GO:0097190 306 0.021
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
response to amino acid GO:0043200 37 0.020
spermatogenesis GO:0007283 284 0.020
endothelial cell migration GO:0043542 44 0.020
regulation of phospholipase c activity GO:1900274 3 0.020
regulation of proteolysis GO:0030162 164 0.020
adaptive immune response GO:0002250 155 0.020
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
cell cell recognition GO:0009988 44 0.020
regulation of microvillus organization GO:0032530 3 0.020
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.020
positive regulation of stem cell proliferation GO:2000648 59 0.020
negative regulation of protein maturation GO:1903318 79 0.020
tissue migration GO:0090130 68 0.020
cellular ion homeostasis GO:0006873 165 0.019
angiogenesis GO:0001525 201 0.019
odontogenesis of dentin containing tooth GO:0042475 66 0.019
ameboidal type cell migration GO:0001667 128 0.019
bone morphogenesis GO:0060349 78 0.019
cellular chemical homeostasis GO:0055082 215 0.019
cellular response to external stimulus GO:0071496 88 0.019
leukocyte migration GO:0050900 124 0.019
positive regulation of t cell costimulation GO:2000525 2 0.019
neuromuscular process GO:0050905 99 0.019
cytokine mediated signaling pathway GO:0019221 115 0.019
peptidyl amino acid modification GO:0018193 336 0.019
response to phenylpropanoid GO:0080184 22 0.019
multi multicellular organism process GO:0044706 109 0.019
telencephalon development GO:0021537 186 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
visual perception GO:0007601 52 0.018
myeloid cell homeostasis GO:0002262 114 0.018
interleukin 12 secretion GO:0072610 3 0.018
multicellular organism growth GO:0035264 161 0.018
ear development GO:0043583 200 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
cellular homeostasis GO:0019725 240 0.018
pallium development GO:0021543 120 0.018
gonad development GO:0008406 141 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
gastrin induced gastric acid secretion GO:0001698 1 0.017
regulation of cell migration GO:0030334 219 0.017
endochondral bone morphogenesis GO:0060350 50 0.017
mitral valve morphogenesis GO:0003183 4 0.017
t cell extravasation GO:0072683 4 0.017
monocarboxylic acid biosynthetic process GO:0072330 61 0.017
somatic stem cell maintenance GO:0035019 47 0.017
negative regulation of angiogenesis GO:0016525 25 0.017
regulation of hematopoietic stem cell migration GO:2000471 1 0.017
progesterone metabolic process GO:0042448 4 0.017
cation homeostasis GO:0055080 212 0.017
sa node cell action potential GO:0086015 4 0.016
response to starvation GO:0042594 65 0.016
cell activation involved in immune response GO:0002263 126 0.016
cell chemotaxis GO:0060326 81 0.016
epithelium migration GO:0090132 63 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
tissue homeostasis GO:0001894 115 0.016
regulation of type 2 immune response GO:0002828 18 0.016
regulation of tube size GO:0035150 57 0.016
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.016
regulation of kinase activity GO:0043549 249 0.016
epithelial cell migration GO:0010631 63 0.016
positive regulation of endothelial cell proliferation GO:0001938 17 0.016
cellular response to lipid GO:0071396 145 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
l amino acid transport GO:0015807 32 0.016
icosanoid metabolic process GO:0006690 33 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
regulation of bone mineralization GO:0030500 31 0.016
regulation of immunological synapse formation GO:2000520 2 0.016
negative regulation of t cell cytokine production GO:0002725 1 0.016
regulation of microvillus assembly GO:0032534 3 0.016
cell recognition GO:0008037 83 0.015
interspecies interaction between organisms GO:0044419 83 0.015
stem cell proliferation GO:0072089 117 0.015
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.015
gland development GO:0048732 330 0.015
interleukin 13 secretion GO:0072611 2 0.015
regulation of innate immune response GO:0045088 91 0.015
striated muscle cell development GO:0055002 125 0.015
negative regulation of interleukin 5 production GO:0032714 4 0.015
inflammatory response GO:0006954 244 0.015
positive regulation of keratinocyte proliferation GO:0010838 4 0.015
natural killer cell activation GO:0030101 44 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
cellular response to acid chemical GO:0071229 68 0.015
vitamin d biosynthetic process GO:0042368 3 0.015
myeloid leukocyte mediated immunity GO:0002444 42 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
protein localization to organelle GO:0033365 185 0.014
macromolecule catabolic process GO:0009057 281 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
catecholamine uptake GO:0090493 4 0.014
cellular response to insulin stimulus GO:0032869 78 0.014
fatty acid biosynthetic process GO:0006633 41 0.014
germ cell development GO:0007281 185 0.014
regulation of mapk cascade GO:0043408 248 0.014
plasma membrane organization GO:0007009 90 0.014
anion transmembrane transport GO:0098656 71 0.014
cofactor metabolic process GO:0051186 80 0.014
cellular response to antibiotic GO:0071236 4 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
t helper 2 cell cytokine production GO:0035745 4 0.014
response to corticosterone GO:0051412 1 0.014
activation of immune response GO:0002253 138 0.014
regulation of nuclear division GO:0051783 56 0.014
lymphocyte differentiation GO:0030098 242 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.014
regulation of phagocytosis GO:0050764 33 0.014
extracellular structure organization GO:0043062 148 0.014
wound healing GO:0042060 157 0.014
positive regulation of cell cycle GO:0045787 92 0.014
muscle cell differentiation GO:0042692 261 0.014
negative regulation of interleukin 13 secretion GO:2000666 1 0.013
regulation of protein maturation GO:1903317 96 0.013
regulation of homeostatic process GO:0032844 182 0.013
stem cell development GO:0048864 219 0.013
protein oligomerization GO:0051259 67 0.013
epithelial cell development GO:0002064 159 0.013
maintenance of location GO:0051235 89 0.013
glycoprotein metabolic process GO:0009100 116 0.013
nucleosome positioning GO:0016584 4 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.013
positive regulation of phospholipase c activity GO:0010863 2 0.013
positive regulation of phagocytosis GO:0050766 26 0.013
negative regulation of type 2 immune response GO:0002829 8 0.013
response to acid chemical GO:0001101 111 0.013
sperm ejaculation GO:0042713 1 0.013
skeletal muscle organ development GO:0060538 163 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of vasculature development GO:1901342 88 0.013
axon ensheathment GO:0008366 76 0.013
cell type specific apoptotic process GO:0097285 268 0.013
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 2 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
positive regulation of protein modification process GO:0031401 299 0.013
palate development GO:0060021 76 0.012
cytoplasmic transport GO:0016482 234 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
porphyrin containing compound metabolic process GO:0006778 22 0.012
cellular response to ammonium ion GO:0071242 2 0.012
appendage development GO:0048736 166 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
negative regulation of cyclase activity GO:0031280 1 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
digestive tract morphogenesis GO:0048546 147 0.012
cellular glucose homeostasis GO:0001678 52 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
chloride transmembrane transport GO:1902476 24 0.012
negative regulation of cell cycle GO:0045786 123 0.012
myelination GO:0042552 74 0.012
positive regulation of ossification GO:0045778 47 0.012
monoamine transport GO:0015844 33 0.012
cellular response to nutrient levels GO:0031669 64 0.012
regulation of muscle tissue development GO:1901861 97 0.012
long chain fatty acid metabolic process GO:0001676 26 0.012
organic acid biosynthetic process GO:0016053 86 0.012
endocrine system development GO:0035270 98 0.012
synaptic transmission glycinergic GO:0060012 2 0.012
regulation of endothelial cell proliferation GO:0001936 23 0.012
response to steroid hormone GO:0048545 56 0.012
proprioception GO:0019230 4 0.012
regulation of angiogenesis GO:0045765 81 0.012
tetrapyrrole metabolic process GO:0033013 22 0.012
response to iron ion GO:0010039 4 0.012
response to peptide hormone GO:0043434 127 0.012
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.012
muscle tissue development GO:0060537 308 0.012
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.012
cellular response to oxidative stress GO:0034599 76 0.012
t cell mediated immunity GO:0002456 50 0.012
regulation of t cell activation GO:0050863 170 0.012
negative regulation of leukocyte mediated immunity GO:0002704 29 0.012
regulation of cell killing GO:0031341 40 0.012
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.011
leukocyte chemotaxis GO:0030595 69 0.011
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
positive regulation of leukocyte differentiation GO:1902107 86 0.011
positive regulation of kinase activity GO:0033674 155 0.011
endomembrane system organization GO:0010256 147 0.011
mapk cascade GO:0000165 281 0.011
positive regulation of nervous system development GO:0051962 221 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
positive regulation of transferase activity GO:0051347 167 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
linoleic acid metabolic process GO:0043651 6 0.011
development of primary sexual characteristics GO:0045137 143 0.011
positive regulation of innate immune response GO:0045089 80 0.011
retina development in camera type eye GO:0060041 119 0.011
sensory perception of light stimulus GO:0050953 54 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
exogenous drug catabolic process GO:0042738 1 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
neutrophil mediated immunity GO:0002446 19 0.011
positive regulation of monocyte extravasation GO:2000439 1 0.011
immune response activating signal transduction GO:0002757 116 0.011
glycerolipid metabolic process GO:0046486 122 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
sensitization GO:0046960 2 0.011
positive regulation of lipid metabolic process GO:0045834 40 0.011
myeloid leukocyte migration GO:0097529 57 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
positive regulation of gliogenesis GO:0014015 27 0.011
response to growth factor GO:0070848 198 0.010
cardiac chamber morphogenesis GO:0003206 93 0.010
regulation of system process GO:0044057 200 0.010
response to histamine GO:0034776 1 0.010
regulation of protein transport GO:0051223 163 0.010
eosinophil activation GO:0043307 1 0.010
respiratory system development GO:0060541 190 0.010
regulation of ossification GO:0030278 112 0.010
exocytosis GO:0006887 121 0.010
positive regulation of cell motility GO:2000147 116 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
regulation of renal sodium excretion GO:0035813 3 0.010
negative regulation of lyase activity GO:0051350 1 0.010
regulation of receptor activity GO:0010469 41 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.010
interaction with symbiont GO:0051702 14 0.010
response to mineralocorticoid GO:0051385 1 0.010
glucose homeostasis GO:0042593 128 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
myotube differentiation GO:0014902 105 0.010
negative regulation of leukocyte apoptotic process GO:2000107 31 0.010
heart trabecula morphogenesis GO:0061384 26 0.010

Enam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.040
inherited metabolic disorder DOID:655 0 0.040
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018